Wdr45 (WD repeat domain 45) - Rat Genome Database

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Gene: Wdr45 (WD repeat domain 45) Rattus norvegicus
Analyze
Symbol: Wdr45
Name: WD repeat domain 45
RGD ID: 1359718
Description: Predicted to enable phosphatidylinositol phosphate binding activity; protein kinase binding activity; and protein-macromolecule adaptor activity. Predicted to be involved in several processes, including autophagy of mitochondrion; macroautophagy; and positive regulation of autophagosome assembly. Predicted to be located in phagophore assembly site. Predicted to be active in cytosol and phagophore assembly site membrane. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation 5. Orthologous to human WDR45 (WD repeat domain 45); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC302559; similar to DNA segment, Chr X, Immunex 38, expressed; WD repeat domain phosphoinositide-interacting protein 4; WD repeat-containing protein 45; WIPI-4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,448,195 - 17,454,117 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX17,448,207 - 17,454,117 (-)EnsemblGRCr8
mRatBN7.2X14,776,280 - 14,782,202 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,776,293 - 14,782,202 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX19,590,311 - 19,596,220 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,486,896 - 20,492,805 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X16,752,063 - 16,757,972 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,621,249 - 15,627,159 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,621,209 - 15,627,235 (-)Ensemblrn6Rnor6.0
Rnor_5.0X16,402,686 - 16,408,439 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X26,816,610 - 26,822,245 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX14,860,493 - 14,866,128 (-)NCBICelera
RGSC_v3.1X26,870,079 - 26,875,714 (-)NCBI
Cytogenetic MapXq12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. null JRS Domain-based curation
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:23435086   PMID:28561066  


Genomics

Comparative Map Data
Wdr45
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,448,195 - 17,454,117 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX17,448,207 - 17,454,117 (-)EnsemblGRCr8
mRatBN7.2X14,776,280 - 14,782,202 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,776,293 - 14,782,202 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX19,590,311 - 19,596,220 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,486,896 - 20,492,805 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X16,752,063 - 16,757,972 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,621,249 - 15,627,159 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,621,209 - 15,627,235 (-)Ensemblrn6Rnor6.0
Rnor_5.0X16,402,686 - 16,408,439 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X26,816,610 - 26,822,245 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX14,860,493 - 14,866,128 (-)NCBICelera
RGSC_v3.1X26,870,079 - 26,875,714 (-)NCBI
Cytogenetic MapXq12NCBI
WDR45
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X49,074,442 - 49,101,178 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX49,074,433 - 49,101,203 (-)Ensemblhg38GRCh38
GRCh37X48,932,101 - 48,958,116 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,819,036 - 48,845,003 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X48,688,548 - 48,714,308NCBI
CeleraX52,706,432 - 52,732,399 (+)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,588,725 - 46,614,834 (-)NCBIHuRef
CHM1_1X48,963,413 - 48,989,776 (-)NCBICHM1_1
T2T-CHM13v2.0X48,486,169 - 48,512,926 (-)NCBIT2T-CHM13v2.0
Wdr45
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,588,212 - 7,594,439 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,580,572 - 7,594,445 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X7,721,987 - 7,728,201 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX7,714,333 - 7,728,206 (+)Ensemblmm10GRCm38
MGSCv37X7,299,375 - 7,305,327 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X6,879,208 - 6,885,160 (+)NCBIMGSCv36mm8
CeleraX3,742,357 - 3,748,359 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.48NCBI
Wdr45
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543597,814 - 603,963 (-)Ensembl
ChiLan1.0NW_004955543597,796 - 604,163 (-)NCBIChiLan1.0ChiLan1.0
WDR45
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,564,448 - 50,592,163 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,567,827 - 50,595,542 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X41,372,722 - 41,400,441 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X49,228,153 - 49,233,960 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX49,224,864 - 49,233,960 (-)EnsemblpanPan2panpan1.1
WDR45
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X42,221,261 - 42,237,535 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX42,218,046 - 42,226,422 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX16,596,869 - 16,613,180 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,357,475 - 42,373,725 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,357,480 - 42,363,342 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,343,804 - 42,360,115 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,331,450 - 42,347,770 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,426,205 - 42,442,519 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Wdr45
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,734,724 - 34,740,594 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721975,104 - 981,731 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936721975,113 - 981,149 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR45
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX43,147,477 - 43,156,234 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X43,150,691 - 43,155,981 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X47,998,631 - 48,003,934 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WDR45
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X46,183,278 - 46,188,564 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX46,183,443 - 46,188,536 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607611,748,609 - 11,754,464 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr45
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893845,701 - 852,244 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624893845,689 - 852,221 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Wdr45
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X14,402,887 - 14,407,021 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Wdr45
19 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:64
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000013369
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X400149344939387Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X197044046970440Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X811148653111486Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X400149324470521Rat

Markers in Region
MARC_3991-3992:996679250:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X14,778,482 - 14,779,975 (+)MAPPERmRatBN7.2
Rnor_6.0X15,623,440 - 15,624,932NCBIRnor6.0
Rnor_5.0X16,404,889 - 16,406,381UniSTSRnor5.0
RGSC_v3.4X26,818,801 - 26,820,293UniSTSRGSC3.4
CeleraX14,862,684 - 14,864,176UniSTS
Cytogenetic MapXq13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001013958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001398795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC130624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000013369   ⟹   ENSRNOP00000013369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX17,448,207 - 17,454,117 (-)Ensembl
mRatBN7.2 EnsemblX14,776,295 - 14,782,202 (-)Ensembl
Rnor_6.0 EnsemblX15,621,209 - 15,627,235 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099569   ⟹   ENSRNOP00000089374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX14,776,293 - 14,781,927 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100366   ⟹   ENSRNOP00000081313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX17,448,207 - 17,454,117 (-)Ensembl
mRatBN7.2 EnsemblX14,776,295 - 14,782,202 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101997   ⟹   ENSRNOP00000088610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX17,448,207 - 17,454,117 (-)Ensembl
mRatBN7.2 EnsemblX14,776,295 - 14,782,202 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118193   ⟹   ENSRNOP00000094004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX17,448,207 - 17,454,117 (-)Ensembl
mRatBN7.2 EnsemblX14,776,295 - 14,782,202 (-)Ensembl
RefSeq Acc Id: NM_001013958   ⟹   NP_001013980
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,207 - 17,453,866 (-)NCBI
mRatBN7.2X14,776,292 - 14,781,951 (-)NCBI
Rnor_6.0X15,621,249 - 15,626,884 (-)NCBI
Rnor_5.0X16,402,686 - 16,408,439 (-)NCBI
RGSC_v3.4X26,816,610 - 26,822,245 (-)RGD
CeleraX14,860,493 - 14,866,128 (-)RGD
Sequence:
RefSeq Acc Id: NM_001398793   ⟹   NP_001385722
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,207 - 17,454,117 (-)NCBI
mRatBN7.2X14,776,292 - 14,782,202 (-)NCBI
RefSeq Acc Id: NM_001398794   ⟹   NP_001385723
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,207 - 17,454,117 (-)NCBI
mRatBN7.2X14,776,292 - 14,782,202 (-)NCBI
RefSeq Acc Id: NM_001398795   ⟹   NP_001385724
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,207 - 17,453,866 (-)NCBI
mRatBN7.2X14,776,292 - 14,781,951 (-)NCBI
RefSeq Acc Id: XM_006256710   ⟹   XP_006256772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,195 - 17,453,872 (-)NCBI
mRatBN7.2X14,776,280 - 14,781,939 (-)NCBI
Rnor_6.0X15,621,249 - 15,626,900 (-)NCBI
Rnor_5.0X16,402,686 - 16,408,439 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256712   ⟹   XP_006256774
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,195 - 17,454,108 (-)NCBI
mRatBN7.2X14,776,280 - 14,782,181 (-)NCBI
Rnor_6.0X15,621,249 - 15,627,159 (-)NCBI
Rnor_5.0X16,402,686 - 16,408,439 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099632   ⟹   XP_038955560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,195 - 17,453,856 (-)NCBI
mRatBN7.2X14,776,280 - 14,781,935 (-)NCBI
RefSeq Acc Id: XM_039099634   ⟹   XP_038955562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,195 - 17,453,755 (-)NCBI
mRatBN7.2X14,776,280 - 14,781,885 (-)NCBI
RefSeq Acc Id: XM_063279923   ⟹   XP_063135993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,195 - 17,452,840 (-)NCBI
RefSeq Acc Id: XM_063279924   ⟹   XP_063135994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,195 - 17,453,870 (-)NCBI
RefSeq Acc Id: XM_063279925   ⟹   XP_063135995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,195 - 17,453,844 (-)NCBI
RefSeq Acc Id: XM_063279926   ⟹   XP_063135996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,448,195 - 17,453,868 (-)NCBI
RefSeq Acc Id: NP_001013980   ⟸   NM_001013958
- Peptide Label: isoform 2
- UniProtKB: Q5U2Y0 (UniProtKB/Swiss-Prot),   A0A8I6AA46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256774   ⟸   XM_006256712
- Peptide Label: isoform X1
- UniProtKB: A0A140TAA5 (UniProtKB/TrEMBL),   A6KP86 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256772   ⟸   XM_006256710
- Peptide Label: isoform X1
- UniProtKB: A0A140TAA5 (UniProtKB/TrEMBL),   A6KP86 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013369   ⟸   ENSRNOT00000013369
RefSeq Acc Id: XP_038955560   ⟸   XM_039099632
- Peptide Label: isoform X1
- UniProtKB: A0A140TAA5 (UniProtKB/TrEMBL),   A6KP86 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955562   ⟸   XM_039099634
- Peptide Label: isoform X1
- UniProtKB: A0A140TAA5 (UniProtKB/TrEMBL),   A6KP86 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000089374   ⟸   ENSRNOT00000099569
Ensembl Acc Id: ENSRNOP00000081313   ⟸   ENSRNOT00000100366
Ensembl Acc Id: ENSRNOP00000088610   ⟸   ENSRNOT00000101997
Ensembl Acc Id: ENSRNOP00000094004   ⟸   ENSRNOT00000118193
RefSeq Acc Id: NP_001385723   ⟸   NM_001398794
- Peptide Label: isoform 1
- UniProtKB: A6KP86 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001385722   ⟸   NM_001398793
- Peptide Label: isoform 1
- UniProtKB: A6KP86 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001385724   ⟸   NM_001398795
- Peptide Label: isoform 1
- UniProtKB: A6KP86 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135994   ⟸   XM_063279924
- Peptide Label: isoform X2
- UniProtKB: A6KP86 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135996   ⟸   XM_063279926
- Peptide Label: isoform X2
- UniProtKB: A6KP86 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135995   ⟸   XM_063279925
- Peptide Label: isoform X2
- UniProtKB: A6KP86 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135993   ⟸   XM_063279923
- Peptide Label: isoform X2
- UniProtKB: A6KP86 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2Y0-F1-model_v2 AlphaFold Q5U2Y0 1-309 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701745
Promoter ID:EPDNEW_R12269
Type:single initiation site
Name:Wdr45_1
Description:WD repeat domain 45
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X15,627,152 - 15,627,212EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359718 AgrOrtholog
BioCyc Gene G2FUF-2914 BioCyc
Ensembl Genes ENSRNOG00000009749 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013369 ENTREZGENE
  ENSRNOT00000099569.1 UniProtKB/Swiss-Prot
  ENSRNOT00000101997 ENTREZGENE
  ENSRNOT00000118193 ENTREZGENE
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7123612 IMAGE-MGC_LOAD
InterPro PROPPIN UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:302559 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94061 IMAGE-MGC_LOAD
NCBI Gene 302559 ENTREZGENE
PANTHER WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED UniProtKB/Swiss-Prot
Pfam WD40 UniProtKB/Swiss-Prot
PhenoGen Wdr45 PhenoGen
RatGTEx ENSRNOG00000009749 RatGTEx
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A140TAA5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZRQ8_RAT UniProtKB/TrEMBL
  A0A8I6AA46 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AL72_RAT UniProtKB/TrEMBL
  A6KP86 ENTREZGENE, UniProtKB/TrEMBL
  Q5U2Y0 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Wdr45  WD repeat domain 45  LOC302559  similar to DNA segment, Chr X, Immunex 38, expressed  Symbol and Name updated 1299863 APPROVED
2005-07-29 LOC302559  similar to DNA segment, Chr X, Immunex 38, expressed      Symbol and Name status set to provisional 70820 PROVISIONAL