Dusp13b (dual specificity phosphatase 13B)

Gene: Dusp13b (dual specificity phosphatase 13B) Rattus norvegicus

Analyze

Symbol:

Dusp13b (Ensembl: LOC108348213)

Name:

dual specificity phosphatase 13B (Ensembl:dual specificity protein phosphatase 13)

RGD ID:

1359712

Description:

Predicted to enable MAP kinase phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in dephosphorylation and negative regulation of MAPK cascade. Predicted to be active in cytoplasm. Orthologous to human DUSP13B (dual specificity phosphatase 13B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-amino-4,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

dual specificity phosphatase 13; dual specificity protein phosphatase 13; Dusp13; LOC108348179; MGC94474; muscle-restricted dual specificity phosphatase; testis and skeletal muscle-specific dual specificity phosphatase

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	2,616,761 - 2,624,434 (+)	NCBI		GRCr8
mRatBN7.2	15	2,567,432 - 2,575,105 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	2,533,547 - 2,575,539 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	2,566,457 - 2,581,840 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	3,952,903 - 3,968,286 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	2,565,257 - 2,580,640 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	2,524,435 - 2,541,734 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	2,734,068 - 2,748,466 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	15	2,733,114 - 2,735,730 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	15	2,526,368 - 2,541,732 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	15	2,526,368 - 2,541,729 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	2,714,150 - 2,729,517 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	2,614,864 - 2,630,230 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	2,622,556 - 2,630,228 (+)	NCBI
Celera	15	2,008,057 - 2,023,408 (-)	NCBI		Celera
Cytogenetic Map	15	p16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Genitopatellar Syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3-dimethoxynaphthalene-1,4-dione (ISO)

2,4-dinitrotoluene (EXP)

2-amino-4,6-dinitrotoluene (EXP)

4-amino-2,6-dinitrotoluene (EXP)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP,ISO)

aflatoxin B1 (EXP,ISO)

aldehydo-D-glucose (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (EXP)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

formaldehyde (ISO)

fucoxanthin (ISO)

gentamycin (EXP)

glucose (ISO)

graphite (EXP)

indole-3-methanol (EXP)

lipopolysaccharide (ISO)

manganese(II) chloride (EXP)

methapyrilene (ISO)

methyl methanesulfonate (ISO)

N-nitrosodiethylamine (EXP)

N-nitrosodimethylamine (ISO)

orphenadrine (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phorbol 13-acetate 12-myristate (ISO)

pirinixic acid (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

tetrachloromethane (EXP)

tributylstannane (EXP)

trichloroethene (EXP)

triptonide (ISO)

tris(2-butoxyethyl) phosphate (ISO)

triticonazole (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of MAPK cascade (IBA)

Cellular Component

cytoplasm (IBA,ISO)

Molecular Function

MAP kinase phosphatase activity (IBA)

myosin phosphatase activity (IEA)

phosphatase activity (ISO)

protein binding (ISO)

protein tyrosine/serine/threonine phosphatase activity (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Molecular cloning and characterization of a novel dual-specificity protein phosphatase possibly involved in spermatogenesis.	Nakamura K, etal., Biochem J 1999 Dec 15;344 Pt 3:819-25.
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11432789	PMID:15252030	PMID:24531476

Genomics

Comparative Map Data

Dusp13b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	2,616,761 - 2,624,434 (+)	NCBI		GRCr8
mRatBN7.2	15	2,567,432 - 2,575,105 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	2,533,547 - 2,575,539 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	2,566,457 - 2,581,840 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	3,952,903 - 3,968,286 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	2,565,257 - 2,580,640 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	2,524,435 - 2,541,734 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	2,734,068 - 2,748,466 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	15	2,733,114 - 2,735,730 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	15	2,526,368 - 2,541,732 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	15	2,526,368 - 2,541,729 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	2,714,150 - 2,729,517 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	2,614,864 - 2,630,230 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	2,622,556 - 2,630,228 (+)	NCBI
Celera	15	2,008,057 - 2,023,408 (-)	NCBI		Celera
Cytogenetic Map	15	p16	NCBI

DUSP13B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	75,094,434 - 75,109,191 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	75,094,432 - 75,109,206 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p14 Ensembl	10	75,094,432 - 75,106,499 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	76,854,192 - 76,868,949 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	76,524,196 - 76,538,976 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	76,524,198 - 76,529,254	NCBI
Celera	10	70,142,445 - 70,157,225 (-)	NCBI		Celera
Cytogenetic Map	10	q22.2	NCBI
HuRef	10	70,852,719 - 70,867,439 (-)	NCBI		HuRef
CHM1_1	10	77,135,938 - 77,150,718 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	75,967,932 - 75,982,690 (-)	NCBI		T2T-CHM13v2.0

Dusp13b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	21,783,463 - 21,792,947 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	21,783,462 - 21,792,947 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	21,733,395 - 21,748,651 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	21,733,394 - 21,751,181 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	22,552,617 - 22,567,844 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	20,521,947 - 20,537,174 (-)	NCBI		MGSCv36	mm8
Celera	14	18,116,274 - 18,131,815 (-)	NCBI		Celera
Cytogenetic Map	14	A3	NCBI
cM Map	14	11.85	NCBI

DUSP13B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	87,251,181 - 87,263,568 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	87,256,506 - 87,266,166 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	71,623,286 - 71,638,049 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	74,287,734 - 74,302,527 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	74,287,734 - 74,302,503 (-)	Ensembl	panpan1.1		panPan2

Dusp13b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	55,739,914 - 55,743,734 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	4,232,565 - 4,245,323 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	4,232,678 - 4,245,199 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DUSP13B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	14	77,660,124 - 77,677,713 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	83,790,369 - 83,804,190 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103215967
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	56,261,811 - 56,276,861 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	56,267,491 - 56,276,844 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	16,755,029 - 16,764,386 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dusp13b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	8,446,329 - 8,457,628 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	8,446,376 - 8,457,678 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Dusp13b
31 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	196
Count of miRNA genes:	104
Interacting mature miRNAs:	109
Transcripts:	ENSRNOT00000017663, ENSRNOT00000067781, ENSRNOT00000074545, ENSRNOT00000074803
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354657	Despr13	Despair related QTL 13		0.0022	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	15	1	29912054	Rat
8552920	Pigfal8	Plasma insulin-like growth factor 1 level QTL 8	3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	15	1	34723002	Rat
8694361	Abfw6	Abdominal fat weight QTL 6	10.2	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	15	1	34723002	Rat
9589149	Insul29	Insulin level QTL 29	9.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	15	1	34723002	Rat
731170	Pur3	Proteinuria QTL 3	2.3	0.0005	urine protein amount (VT:0005160)	urine protein excretion rate (CMO:0000759)	15	1	41686771	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	42356671	Rat
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	55302115	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	306329	45306329	Rat
5684946	Bss98	Bone structure and strength QTL 98	3.9	0.0026	tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	15	1058250	14481294	Rat
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	colorectal tumor number (CMO:0001794)	15	2266368	22711984	Rat
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	15	2266368	22711984	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2266368	46921453	Rat

Markers in Region

RH94133

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	2,574,665 - 2,574,820 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	2,541,295 - 2,541,449	NCBI	Rnor6.0
Rnor_6.0	15	2,748,018 - 2,748,172	NCBI	Rnor6.0
Rnor_5.0	15	2,523,052 - 2,523,206	UniSTS	Rnor5.0
Rnor_5.0	15	2,729,076 - 2,729,230	UniSTS	Rnor5.0
RGSC_v3.4	15	2,629,791 - 2,629,945	UniSTS	RGSC3.4
Celera	15	2,008,342 - 2,008,496	UniSTS
Cytogenetic Map	15	p16	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	circulatory system	endocrine system	hemolymphoid system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	appendage
High
Medium							7
Low				8	11		1		8
Below cutoff	9	6	2			3	13	5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001007006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003751425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003751426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599731	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC083646	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000017663 ⟹ ENSRNOP00000017663

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	2,559,763 - 2,575,539 (+)	Ensembl
Rnor_6.0 Ensembl	15	2,734,068 - 2,748,466 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000048713 ⟹ ENSRNOP00000051508

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	2,559,737 - 2,575,100 (+)	Ensembl
Rnor_6.0 Ensembl	15	2,526,368 - 2,541,729 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000067781 ⟹ ENSRNOP00000058941

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	2,567,432 - 2,575,098 (+)	Ensembl
Rnor_6.0 Ensembl	15	2,740,784 - 2,748,450 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000074545 ⟹ ENSRNOP00000064546

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	15	2,733,114 - 2,735,730 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000074803 ⟹ ENSRNOP00000066962

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	2,533,547 - 2,575,539 (+)	Ensembl
Rnor_6.0 Ensembl	15	2,526,368 - 2,541,729 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089013 ⟹ ENSRNOP00000075061

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	2,563,139 - 2,575,539 (+)	Ensembl
Rnor_6.0 Ensembl	15	2,527,343 - 2,541,732 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000101834 ⟹ ENSRNOP00000080776

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	2,563,139 - 2,575,539 (+)	Ensembl

RefSeq Acc Id:

NM_001007006 ⟹ NP_001007007

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	2,616,761 - 2,624,434 (+)	NCBI
mRatBN7.2	15	2,567,432 - 2,575,105 (+)	NCBI
Rnor_6.0	15	2,534,061 - 2,541,734 (+)	NCBI
Rnor_5.0	15	2,714,150 - 2,729,517 (+)	NCBI
RGSC_v3.4	15	2,614,864 - 2,630,230 (+)	RGD
Celera	15	2,008,057 - 2,015,722 (-)	NCBI

Sequence:

show sequence

TCCTGGCCCCAGACCATGCCCTAGGTAGGGGGCAGGCCACTCAGCCTGCCAGAGAGGTCACAGA
GGGGGATGAGGGAGAAAGGCCGGTCCTCCCTTCCGTTCAACTCACCATCCACTCGCTGGGTGAG
TGTGGCCAAGCCAGTGGCCTCCTGGGTGCCGGTTTCTTTTTCTGGTCTTGGCAATGCCTACCAG
AGGGAAAAGATGCTCTACCCAGTCTGTACCTTCTCTAGTTACTCCTTGAGGGAACCAGGGGCAG
TTGGCCAAGGTAGGTCCCTCTTCCCTCTAAGGCACCAGGCCCGGGTTCTGGTGCCTCTGACACC
TCAGTTCTGCAAGGTCCCGGATGGCCTGAGCCAGCTGACTCCAGACACAACTCACTCCATCCCA
GTGAGGCCTGCACAGATGCACTGGCCTGAACCACAAGGGATGGACTCGCTGCAGAAGCAGGAAC
TCCGGAAGCCAAAGATTCATGGGGCAGTCCAGGTGTCCCCGTACCAGCCACCCACGCTGGCCTC
ACTACAGCGATTGCTGTGGGTCCGTCGGACCTCCACGCTGACCCACATCAATGAAGTCTGGCCC
AACCTTTTCTTGGGAGATGCGTATGCTGCCAGAGACAAGAGCCGTCTAATCCAGCTGGGCATTA
CCCATGTCGTAAATGTTGCTGCGGGCAAGTTTCAGGTGGACACAGGCGCCAAGTTTTACCGTGG
AACACCCGTGGAGTACTATGGCATTGAGGCCGATGATAACCCCTTCTTTGACCTCAGTGTCTAC
TTTCTGCCTGTTGCTCGTTACATCAGAGATGCCCTCAATACTCCCCGAAGCCGAGTGCTGGTCC
ACTGCGCCATGGGGGTAAGCCGCTCTGCTACAATTGTCCTGGCCTTCCTCATGATCTTCGAGAA
TATGACACTGGTAGACGCCATCCAGACGGTGCAGGCCCACCGAGATATCTGTCCCAACTCAGGC
TTCCTCCGACAGCTCCAGGTTCTGGACAATAGGCTGAGGCGGGAAACAGGGAGACTCTGAATTA
GGGAGCACTTGAAGCCCTGACTCCTCCATCCAGCGTGGCCTAACCTGACTTACCTGGCCCTGGG
AATGGCAGCCTTGGCTGTTTCCAGAGTCCCTGAGATGGCACCAGCAAGTCAGGGCTCCGCTGAA
GCAGAGGCAGGGTGGGCTGGGTGGCAGCCCTCAACAAGTGGAGTCCCCTGACACAGCAGAGAAA
TTCTTTATGCAGAAGAAATTTCAGACTGTCTCTATAATAAAAGGTTCATCATAATAAAAAAAAA
AAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001007007	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83646	(Get FASTA)	NCBI Sequence Viewer
	AAI66532	(Get FASTA)	NCBI Sequence Viewer
	EDL86271	(Get FASTA)	NCBI Sequence Viewer
	EDL86272	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017663.5
	ENSRNOP00000058941.2
	ENSRNOP00000066962.3
	ENSRNOP00000075061.2
	ENSRNOP00000080776.1

RefSeq Acc Id:

NP_001007007 ⟸ NM_001007006

- UniProtKB:

Q5XIN2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDSLQKQELRKPKIHGAVQVSPYQPPTLASLQRLLWVRRTSTLTHINEVWPNLFLGDAYAARDK
SRLIQLGITHVVNVAAGKFQVDTGAKFYRGTPVEYYGIEADDNPFFDLSVYFLPVARYIRDALN
TPRSRVLVHCAMGVSRSATIVLAFLMIFENMTLVDAIQTVQAHRDICPNSGFLRQLQVLDNRLR
RETGRL

hide sequence

RefSeq Acc Id:

ENSRNOP00000058941 ⟸ ENSRNOT00000067781

RefSeq Acc Id:

ENSRNOP00000075061 ⟸ ENSRNOT00000089013

RefSeq Acc Id:

ENSRNOP00000051508 ⟸ ENSRNOT00000048713

RefSeq Acc Id:

ENSRNOP00000066962 ⟸ ENSRNOT00000074803

RefSeq Acc Id:

ENSRNOP00000017663 ⟸ ENSRNOT00000017663

RefSeq Acc Id:

ENSRNOP00000064546 ⟸ ENSRNOT00000074545

RefSeq Acc Id:

ENSRNOP00000080776 ⟸ ENSRNOT00000101834

Protein Domains

Tyrosine specific protein phosphatases Tyrosine-protein phosphatase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0R587-F1-model_v2	AlphaFold	M0R587	1-188	view protein structure
AF-A0A0G2K9N1-F1-model_v2	AlphaFold	A0A0G2K9N1	1-304	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359712	AgrOrtholog
BioCyc Gene	G2FUF-14599	BioCyc
Ensembl Genes	ENSRNOG00000013112	Ensembl
	ENSRNOG00000048428	Ensembl
	ENSRNOG00000057795	Ensembl
	ENSRNOG00000060401	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000017663.7	UniProtKB/TrEMBL
	ENSRNOT00000067781.2	UniProtKB/TrEMBL
	ENSRNOT00000074803.3	UniProtKB/TrEMBL
	ENSRNOT00000089013.2	UniProtKB/TrEMBL
	ENSRNOT00000101834.1	UniProtKB/TrEMBL
Gene3D-CATH	3.90.190.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7135038	IMAGE-MGC_LOAD
	IMAGE:7190084	IMAGE-MGC_LOAD
InterPro	Dual-sp/Tyr_phosphatase	UniProtKB/TrEMBL
	Dual-sp_phosphatase_cat-dom	UniProtKB/TrEMBL
	Dual-sp_phosphatase_famA	UniProtKB/TrEMBL
	Dual-sp_phosphatase_subgr_cat	UniProtKB/TrEMBL
	Prot-tyrosine_phosphatase-like	UniProtKB/TrEMBL
	Tyr_Pase_AS	UniProtKB/TrEMBL
KEGG Report	rno:361002	UniProtKB/TrEMBL
MGC_CLONE	MGC:188125	IMAGE-MGC_LOAD
	MGC:94474	IMAGE-MGC_LOAD
NCBI Gene	361002	ENTREZGENE
PANTHER	DUAL SPECIFICITY PROTEIN PHOSPHATASE	UniProtKB/TrEMBL
	DUAL SPECIFICITY PROTEIN PHOSPHATASE 13 ISOFORM B	UniProtKB/TrEMBL
	PTHR45682	UniProtKB/TrEMBL
Pfam	DSPc	UniProtKB/TrEMBL
PhenoGen	Dusp13b	PhenoGen
PRINTS	ADSPHPHTASE	UniProtKB/TrEMBL
	ADSPHPHTASEA	UniProtKB/TrEMBL
PROSITE	TYR_PHOSPHATASE_1	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_2	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_DUAL	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013112	RatGTEx
	ENSRNOG00000048428	RatGTEx
	ENSRNOG00000057795	RatGTEx
	ENSRNOG00000060401	RatGTEx
SMART	DSPc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52799	UniProtKB/TrEMBL
UniProt	A0A0G2K9N1_RAT	UniProtKB/TrEMBL
	A0A8I6G515_RAT	UniProtKB/TrEMBL
	F6Z8N5_RAT	UniProtKB/TrEMBL
	F7EXD6_RAT	UniProtKB/TrEMBL
	M0RBM2_RAT	UniProtKB/TrEMBL
	Q5XIN2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-05-11	Dusp13b	dual specificity phosphatase 13B	Dusp13	dual specificity phosphatase 13	Name and Symbol changed	629549	APPROVED
2021-03-09	Dusp13	dual specificity phosphatase 13	LOC108348179	dual specificity protein phosphatase 13	Data merged from RGD:11502706	737654	PROVISIONAL
2016-08-02	LOC108348179	dual specificity protein phosphatase 13			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-07-29	Dusp13	dual specificity phosphatase 13			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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