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Gene: Dnajb12 (DnaJ heat shock protein family (Hsp40) member B12) Rattus norvegicus

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Symbol:

Dnajb12

Name:

DnaJ heat shock protein family (Hsp40) member B12

RGD ID:

1359677

Description:

Predicted to enable Hsp70 protein binding activity. Predicted to be involved in several processes, including ERAD pathway; cellular response to misfolded protein; and protein folding. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

DnaJ (Hsp40) homolog, subfamily B, member 12; dnaJ homolog subfamily B member 12; LOC100362018; LOC294513; MGC94679; similar to DnaJ (Hsp40) homolog, subfamily B, member 12

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Mus musculus (house mouse):	Dnajb12 (DnaJ heat shock protein family (Hsp40) member B12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dnajb12 (DnaJ heat shock protein family (Hsp40) member B12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dnajb12 (DnaJ heat shock protein family (Hsp40) member B12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dnajb12 (DnaJ heat shock protein family (Hsp40) member B12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Dnajb12 (DnaJ heat shock protein family (Hsp40) member B12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dnajb12 (DnaJ heat shock protein family (Hsp40) member B12)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dnajb12a (DnaJ heat shock protein family (Hsp40) member B12a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dnajb12b (DnaJ heat shock protein family (Hsp40) member B12b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	HLJ1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	HLJ1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG3061	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG3061	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	dnj-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	dnj-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	dnajb12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	dnajb12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	28,371,180 - 28,389,390 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	28,371,199 - 28,389,389 (+)	Ensembl				GRCr8
mRatBN7.2	20	27,828,216 - 27,846,428 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	27,828,235 - 27,846,427 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	28,839,821 - 28,858,023 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	28,226,094 - 28,244,296 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	28,968,945 - 28,987,131 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	29,445,510 - 29,463,739 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	29,445,510 - 29,463,738 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	31,249,072 - 31,266,938 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	27,188,065 - 27,206,148 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	29,269,844 - 29,288,037 (+)	NCBI		Celera
RGSC_v3.1	20	27,201,864 - 27,219,947 (+)	NCBI
Cytogenetic Map	20	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

actinomycin D (ISO)

aflatoxin B1 (ISO)

amiodarone (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

Brodifacoum (EXP)

butanal (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

Dibutyl phosphate (ISO)

entinostat (ISO)

finasteride (EXP)

flutamide (EXP)

GSK-J4 (ISO)

leflunomide (EXP)

methimazole (EXP)

nefazodone (EXP)

Nutlin-3 (ISO)

ozone (EXP)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

pirinixic acid (ISO)

piroxicam (ISO)

sodium arsenite (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

Triptolide (EXP)

triticonazole (EXP)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to misfolded protein (IBA,IEA,ISO)

ERAD pathway (IEA,ISO)

protein folding (IBA,IEA,ISO)

protein-containing complex assembly (IEA,ISO)

Cellular Component

endoplasmic reticulum (IEA,ISO)

endoplasmic reticulum membrane (IBA,IEA,ISO)

nuclear membrane (IEA,ISO)

Molecular Function

Hsp70 protein binding (IBA,IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Endoplasmic Reticulum-associated degradation pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:19946888	PMID:21148293	PMID:21150129	PMID:27916661

Genomics

Comparative Map Data

Dnajb12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	28,371,180 - 28,389,390 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	28,371,199 - 28,389,389 (+)	Ensembl				GRCr8
mRatBN7.2	20	27,828,216 - 27,846,428 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	27,828,235 - 27,846,427 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	28,839,821 - 28,858,023 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	28,226,094 - 28,244,296 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	28,968,945 - 28,987,131 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	29,445,510 - 29,463,739 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	29,445,510 - 29,463,738 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	31,249,072 - 31,266,938 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	27,188,065 - 27,206,148 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	29,269,844 - 29,288,037 (+)	NCBI		Celera
RGSC_v3.1	20	27,201,864 - 27,219,947 (+)	NCBI
Cytogenetic Map	20	q11	NCBI

DNAJB12
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	72,332,863 - 72,354,919 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	72,332,830 - 72,355,167 (-)	Ensembl			hg38	GRCh38
GRCh37	10	74,092,621 - 74,114,677 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	73,762,594 - 73,784,875 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	10	73,762,593 - 73,784,875	NCBI
Celera	10	67,379,461 - 67,399,258 (-)	NCBI		Celera
Cytogenetic Map	10	q22.1	NCBI
HuRef	10	68,086,789 - 68,109,106 (-)	NCBI		HuRef
CHM1_1	10	74,374,374 - 74,396,719 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	73,203,895 - 73,225,949 (-)	NCBI		T2T-CHM13v2.0

Dnajb12
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	59,715,405 - 59,735,118 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	59,715,378 - 59,735,124 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	59,879,583 - 59,899,296 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	59,879,556 - 59,899,302 (+)	Ensembl			mm10	GRCm38
MGSCv37	10	59,342,339 - 59,360,764 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	59,274,948 - 59,293,373 (+)	NCBI		MGSCv36	mm8
Celera	10	60,977,044 - 60,995,371 (+)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI
cM Map	10	29.64	NCBI

Dnajb12
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	19,266,206 - 19,288,854 (+)	Ensembl
ChiLan1.0	NW_004955437	19,266,206 - 19,285,654 (+)	NCBI	ChiLan1.0	ChiLan1.0

DNAJB12
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	84,480,641 - 84,503,970 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	84,485,962 - 84,508,244 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	68,852,913 - 68,875,307 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	71,319,836 - 71,341,876 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	71,319,836 - 71,341,789 (-)	Ensembl			panPan2	panpan1.1

DNAJB12
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	22,964,098 - 22,980,291 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	22,965,967 - 22,980,292 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	23,102,398 - 23,118,625 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	23,243,979 - 23,261,880 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	23,245,766 - 23,261,871 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	23,145,129 - 23,163,017 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	23,345,955 - 23,363,911 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	23,699,654 - 23,717,628 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Dnajb12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	58,091,183 - 58,113,019 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	6,583,908 - 6,607,628 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	6,583,828 - 6,605,744 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DNAJB12
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	75,169,077 - 75,189,883 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	75,169,076 - 75,190,109 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	81,218,690 - 81,239,723 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DNAJB12
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	58,954,908 - 58,976,453 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	58,955,201 - 58,976,943 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666048	19,568,334 - 19,592,009 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dnajb12
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	6,131,271 - 6,149,522 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624754	6,131,180 - 6,149,597 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Dnajb12
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	18	25,714,865 - 25,733,278 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Dnajb12
118 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	262
Count of miRNA genes:	160
Interacting mature miRNAs:	198
Transcripts:	ENSRNOT00000044805
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	4189476	49189476	Rat
2303587	Bw93	Body weight QTL 93	13		body mass (VT:0001259)	body weight (CMO:0000012)	20	26689362	56021148	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1	33724594	Rat
4889870	Pur30	Proteinuria QTL 30	19	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	8043920	29865039	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600300	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1533083	46533083	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	1	34066551	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29193376	Rat
2303626	Vencon10	Ventilatory control QTL 10		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	20	20745585	56021148	Rat
1598869	Memor6	Memory QTL 6	3.1		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	20	26689362	56021148	Rat
1598870	Bp289	Blood pressure QTL 289	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	8216359	53216359	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29193376	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29193376	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29193376	Rat
1598858	Cm61	Cardiac mass QTL 61	3.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	20	8216359	53216359	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29193376	Rat
1331747	Hrtrt16	Heart rate QTL 16	3.163		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	20	26792353	56021148	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	12243242	49189476	Rat
2303578	Gluco50	Glucose level QTL 50	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	20	26689362	56021148	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578510	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600300	Rat
2300188	Bmd68	Bone mineral density QTL 68	6.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	20	26689362	56021148	Rat

Markers in Region

RH141822

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	27,846,086 - 27,846,305 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	29,463,399 - 29,463,616	NCBI	Rnor6.0
Rnor_5.0	20	31,266,598 - 31,266,815	UniSTS	Rnor5.0
RGSC_v3.4	20	27,205,808 - 27,206,025	UniSTS	RGSC3.4
Celera	20	29,287,697 - 29,287,914	UniSTS
Cytogenetic Map	20	q11	UniSTS

UniSTS:236356

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	27,845,481 - 27,845,675 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	29,462,794 - 29,462,987	NCBI	Rnor6.0
Rnor_5.0	20	31,265,993 - 31,266,186	UniSTS	Rnor5.0
RGSC_v3.4	20	27,205,203 - 27,205,396	UniSTS	RGSC3.4
Celera	20	29,287,092 - 29,287,285	UniSTS
Cytogenetic Map	20	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC096404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC090076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223748	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000044805 ⟹ ENSRNOP00000049600

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	28,371,199 - 28,389,389 (+)	Ensembl
mRatBN7.2 Ensembl	20	27,828,235 - 27,846,427 (+)	Ensembl
Rnor_6.0 Ensembl	20	29,445,510 - 29,463,738 (+)	Ensembl

RefSeq Acc Id:

NM_001013907 ⟹ NP_001013929

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	28,371,180 - 28,389,390 (+)	NCBI
mRatBN7.2	20	27,828,216 - 27,846,428 (+)	NCBI
Rnor_6.0	20	29,445,510 - 29,463,739 (+)	NCBI
Rnor_5.0	20	31,249,072 - 31,266,938 (+)	NCBI
RGSC_v3.4	20	27,188,065 - 27,206,148 (+)	RGD
Celera	20	29,269,844 - 29,288,037 (+)	RGD

Sequence:

show sequence

GAAGGAGGGGCGGAGGGTTATGTCATCCTTCCGCGCCGGCCTGCCCCGCGACGCGCCGGCGGCT
GGCGCAGCCCTTCGCTCGCCCGGCCTCCCCCTCCCTGGTTCCGTGCTCGGGTTCCGCCATGGAA
TCCAACAAGGATGAAGCCGAGCGCTGTATCAGCATCGCCCTCAAGGCCATCCAAAGCAACCAGC
CCGACCGGGCGCTGCGCTTCCTGGAGAAGGCGCAGCGGCTGTACCCGACGCCAAGAGTCACCGC
TCTGATCGAGTCCCTCAACCAAAAATCACAGTCCGCCGGTGATCAATCTCAACCCACAGACACA
ACCCATACCACCACCAGGAAGACAAGCGGGACCGAAACCCCCTCAGCCAACGGTGAGGCAGGAG
GAGGAGAGAGCACCAAGGGCTATACTTCAGAGCAGGTGGCAGCTGTGAAAAGGGTCAAGCAGTG
TAAAGATTACTATGAGATCCTTGGGGTAAGCAGAAGCGCCTCAGACGAGGACCTGAAGAAGGCC
TACCGCAAACTGGCCCTCAAATTCCATCCAGACAAGAACCACGCGCCTGGGGCCACCGAAGCTT
TCAAAGCCATTGGCACAGCATATGCCGTCCTCAGCAACCCGGAGAAAAGGAAACAGTACGACCA
GTTTGGTGATGACAAGAACCAGGCTGCCCGGCACGGCCATAGCCACGGGGACTTCCACCGAGGC
TTTGAAGCCGACATCTCCCCAGAAGACCTCTTTAACATGTTCTTTGGTGGTGGCTTTCCTTCCA
GTAACGTCCATGTCTACAGCAATGGCCGAATGCGATACACCTACCAGCAGAGACAGGACCGCAG
AGACAACCAGGGTGATGGCGGGCTAGGAGTATTCGTCCAGCTGATGCCCATCCTCATCCTCATC
CTCGTGTCGGCGCTCAGCCAGCTCATGGTGTCCAGTCCACCCTACAGCCTGAGCCCCAGACCGT
CAGTGGGCCATATCCACAAGCGAGTCACTGACCACCTGAACGTCGCGTACTACGTGGCAGACAC
CTTCTCTGAAGAGTACACAGGCTCTAGCCTCAAAACAGTTGAACGGAATGTGGAAGACGATTAT
ATCGCCAACCTCCGAAACAACTGCTGGAAGGAAAAGCAACAGAAGGAAGGCTTGCTGTACCGAG
CCCGATACTTTGGTGACACAGACATGTACCACAGAGCACAGAAGATGAGCACCCCGAGTTGCAG
TCGGCTGTCAGAGACTATGAAATCCCTGGAGAATTTTTGGTGACACACACTGAGCCAGCCAAGG
TGATGGACTATATATTTAAGTAAAGACATGCACAGAAAAAATTAAAATGGACTGGAGGCCGAAC
ACCGCACAACCGTCCTCTCTCAGCCCGTGAATGCGGAAAGCTCTTAGGACGGACAGAAAGCCTG
CCTGGGGCTGCTTCCTCCTCTCCCAGGGCTGGCAAGAAGCTCTGCATCGCCGGCTCCTAGGATA
CCGAAACCATGGCAACGAAAGTAGAATGTAAAACTTGCAGCAAATGTCTGTGGGGAAGGACTGG
GGGAGGGGATGCCCCACTGTCTCTCCTCCCCCTCCCTGGAGCTGCCACCAGTCACTCCCAGGAG
AAACCAGGCAGAGGCATGGGCCAAGGAACAGAGGAGAAAATTCCAGAGAACATAACTTAGAAAT
GCGTACGTATGTATATATATCTATTTATATGTAAATAGACATATATAAAGATATATATATATAT
ATAAAGTCTTTTAAAACTATGCAGGGATTGGATTAAGATGTTCAGCTGACTTGCTCCATACTTT
AGAAAACCGGGCCTGTTTGGGAAGGCGGCCTGGCTTTCAAAAGCTTGACAGTAACTGTAGCCGA
CAGCATAGGGAAAGTCAGATCAGACACTGTTAGTGTTGCCCTTAGCCCCAGCCTGACTGATGGC
AGCAGTAATCATGGTGGTACAAATCCATAGAAAACTCCCAAAGGTCTCCAGGCTTATGGCTAAG
GTGGGGGAGCAAGCTGGGGGCAGGAACGGTGCCTGCCCCTGGAGATAGCTGCTCAGTATTGGGC
CATAGCAGAGATCTCAGACAAGGCCCGCTGGGAAGAGGCCTGCTCCTCACGCTGCCTCCTCCTT
GGCCAGCCTCAGGTGGGCTCTCTGCCCTAATGCCCAGGAGCCCTGCAGCCACTCCCCTGCCCAT
ACCTCTTCCCCACCCAAGTCCCCAGGTGGGTTTGCCTTACAGGTGCCACAGGGCACAGCTTCAC
CATTGCCAACAGGTTTTCTCTAAGTTGTGCACCAAGGACTCCAGAAGGCTCTTCCTCCAAAAGC
TGAACCAGGACCTGAGTGCAGCCCAGCTTGTGGAGAACCAGGGCTGCAAGTGCCTGTCTTCTCC
ACAGTGGGCCCACTGGGTTCCACTCGTTGGATGGAGGATCCACCACGACCAGAATGGCTTCCCC
CTTCAGATGAGGACGGTTTACCCTCCTCCCACGTCTATAATGGGCCTTTGGGGACTGCTGTCCC
CTAGTTTTCCTATGGCCGTGGGTGTGCTCTTGCACCTGCTGACTTCCAAAGCCTTACTTCCCCA
AGCTGCCAGCCCAGAGGTCGGAACTGTCCCCCCAGGGTCTCTCTCTCTCTCTCTCTTTTTTTTT
TTAATACAACCCCCTAACAGATAGGGTGCTGGGAAAGGAAGCTTGGTTAGGAATTGTCAAATCT
GTTGGTTTTTTTTTTTTTTTTTTTTTTAAACAAAGTCCCACCCTGCAATGAAGTGGCCACCCTG
GCCTAGAGAGATAATAACTGGATGCAGGCCAGAGTACCCCACCCACAGTGGCCTGGTGCTCTGC
CTCCCACCACCCCAACTGTCTGGTCTTGGTAGCTGTCCCTAGAGGGGCTGAGCCATGTGCAATA
AGAACACAGATCCTAAAGGATCCCTGAGAAGCTGTATTTCTTGAATTAGAACTCTGATATTGTA
CATCTATAAATATATGTTTATTATGTGATTGGCAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039098616 ⟹ XP_038954544

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	28,371,219 - 28,389,390 (+)	NCBI
mRatBN7.2	20	27,828,218 - 27,846,428 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001013929	(Get FASTA)	NCBI Sequence Viewer
	XP_038954544	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH90076	(Get FASTA)	NCBI Sequence Viewer
	EDL93065	(Get FASTA)	NCBI Sequence Viewer
	EDL93067	(Get FASTA)	NCBI Sequence Viewer
	EDL93068	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000049600
	ENSRNOP00000049600.4

RefSeq Acc Id:

NP_001013929 ⟸ NM_001013907

- UniProtKB:

Q5FVC4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MESNKDEAERCISIALKAIQSNQPDRALRFLEKAQRLYPTPRVTALIESLNQKSQSAGDQSQPT
DTTHTTTRKTSGTETPSANGEAGGGESTKGYTSEQVAAVKRVKQCKDYYEILGVSRSASDEDLK
KAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKNQAARHGHSHGDFH
RGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILI
LILVSALSQLMVSSPPYSLSPRPSVGHIHKRVTDHLNVAYYVADTFSEEYTGSSLKTVERNVED
DYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMSTPSCSRLSETMKSLENFW

hide sequence

Ensembl Acc Id:

ENSRNOP00000049600 ⟸ ENSRNOT00000044805

RefSeq Acc Id:	XP_038954544 ⟸ XM_039098616
- Peptide Label:	isoform X1
- UniProtKB:	F7F4L4 (UniProtKB/TrEMBL), A6K3V6 (UniProtKB/TrEMBL)

Protein Domains

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5FVC4-F1-model_v2	AlphaFold	Q5FVC4	1-378	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701593

Promoter ID:

EPDNEW_R12116

Type:

initiation region

Name:

Dnajb12_1

Description:

DnaJ heat shock protein family member B12

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	29,445,537 - 29,445,597	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359677	AgrOrtholog
BioCyc Gene	G2FUF-3758	BioCyc
Ensembl Genes	ENSRNOG00000030408	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000044805	ENTREZGENE
	ENSRNOT00000044805.5	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.110	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7192431	IMAGE-MGC_LOAD
InterPro	DnaJ_dom_sf	UniProtKB/TrEMBL
	DnaJ_N	UniProtKB/TrEMBL
	DnaJ_subfamily_B/C	UniProtKB/TrEMBL
	DUF1977_DnaJ-like	UniProtKB/TrEMBL
	Heat_shock_DnaJ_CS	UniProtKB/TrEMBL
KEGG Report	rno:294513	UniProtKB/TrEMBL
MGC_CLONE	MGC:94679	IMAGE-MGC_LOAD
NCBI Gene	294513	ENTREZGENE
PANTHER	AT29763P-RELATED	UniProtKB/TrEMBL
	DNAJ HOMOLOG SUBFAMILY B MEMBER 12	UniProtKB/TrEMBL
Pfam	DnaJ	UniProtKB/TrEMBL
	DUF1977	UniProtKB/TrEMBL
PhenoGen	Dnajb12	PhenoGen
PRINTS	DNAJPROTEIN	UniProtKB/TrEMBL
PROSITE	DNAJ_1	UniProtKB/TrEMBL
	DNAJ_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000030408	RatGTEx
SMART	DnaJ	UniProtKB/TrEMBL
Superfamily-SCOP	DnaJ_N	UniProtKB/TrEMBL
UniProt	A6K3V6	ENTREZGENE, UniProtKB/TrEMBL
	F7F4L4	ENTREZGENE, UniProtKB/TrEMBL
	Q5FVC4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-25	Dnajb12	DnaJ heat shock protein family (Hsp40) member B12	Dnajb12	DnaJ (Hsp40) homolog, subfamily B, member 12	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-07-29	Dnajb12	DnaJ (Hsp40) homolog, subfamily B, member 12	LOC100362018	DnaJ (Hsp40) homolog, subfamily B, member 12	Data merged from RGD:2318962	737654	PROVISIONAL
2010-05-05	LOC100362018	DnaJ (Hsp40) homolog, subfamily B, member 12			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-03-04	Dnajb12	DnaJ (Hsp40) homolog, subfamily B, member 12	LOC294513	similar to DnaJ (Hsp40) homolog, subfamily B, member 12	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-29	LOC294513	similar to DnaJ (Hsp40) homolog, subfamily B, member 12			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)