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Gene: Cptp (ceramide-1-phosphate transfer protein) Rattus norvegicus

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Symbol:

Cptp

Name:

ceramide-1-phosphate transfer protein

RGD ID:

1359656

Description:

Predicted to enable ceramide 1-phosphate binding activity and ceramide 1-phosphate transfer activity. Predicted to be involved in several processes, including ceramide 1-phosphate transport; negative regulation of NLRP3 inflammasome complex assembly; and negative regulation of metabolic process. Predicted to be located in Golgi apparatus; bounding membrane of organelle; and plasma membrane. Predicted to be active in cytosol. Orthologous to human CPTP (ceramide-1-phosphate transfer protein); INTERACTS WITH bisphenol A; gentamycin; paracetamol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Gltpd1; glycolipid transfer protein domain containing 1; glycolipid transfer protein domain-containing protein 1; MGC94339; similar to BC002216 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CPTP (ceramide-1-phosphate transfer protein)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cptp (ceramide-1-phosphate transfer protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cptp (ceramide-1-phosphate transfer protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CPTP (ceramide-1-phosphate transfer protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CPTP (ceramide-1-phosphate transfer protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cptp (ceramide-1-phosphate transfer protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CPTP (ceramide-1-phosphate transfer protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CPTP (ceramide-1-phosphate transfer protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cptp (ceramide-1-phosphate transfer protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cptp (ceramide-1-phosphate transfer protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DCPH1 (damage control phosphatase 1)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Cptp (ceramide-1-phosphate transfer protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CPTP (ceramide-1-phosphate transfer protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cptp (ceramide-1-phosphate transfer protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cptp (ceramide-1-phosphate transfer protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG30392	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	K08E4.2	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tag-296	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cptp	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cptp	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Related Pseudogenes:

Cptp-ps1

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	171,757,181 - 171,761,271 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	171,757,181 - 171,761,266 (-)	Ensembl				GRCr8
mRatBN7.2	5	166,474,947 - 166,479,103 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	166,474,966 - 166,479,017 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	169,179,617 - 169,183,722 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	171,001,038 - 171,005,143 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	170,963,569 - 170,967,674 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	173,314,219 - 173,318,384 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	173,314,228 - 173,318,313 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	176,789,844 - 176,794,000 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	172,723,909 - 172,727,994 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	164,675,665 - 164,679,750 (-)	NCBI		Celera
RGSC_v3.1	5	172,734,403 - 172,738,489 (-)	NCBI
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,4'-trichlorobiphenyl (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

cobalt dichloride (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibenz[a,h]anthracene (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

gentamycin (EXP)

indometacin (ISO)

iron dichloride (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

metformin (ISO)

methamphetamine (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

potassium chromate (ISO)

resveratrol (ISO)

rotenone (ISO)

sodium arsenite (ISO)

Soman (EXP)

sunitinib (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (EXP)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ceramide 1-phosphate transport (ISO,ISS)

ceramide transport (IBA)

glycolipid transport (ISO)

intermembrane lipid transfer (IBA,IEA)

lipid transport (IEA)

negative regulation of autophagy (ISO,ISS)

negative regulation of interleukin-1 beta production (IEA,ISO,ISS)

negative regulation of NLRP3 inflammasome complex assembly (ISO,ISS)

Cellular Component

cytoplasm (IEA)

cytosol (IBA,IEA,ISO)

endosome membrane (IEA)

Golgi apparatus (IEA)

nuclear outer membrane (IEA)

plasma membrane (IEA)

trans-Golgi network membrane (ISO)

Molecular Function

ceramide 1-phosphate binding (IBA,ISO,ISS)

ceramide 1-phosphate transfer activity (IBA,ISO,ISS)

lipid binding (IEA)

lipid transfer activity (IEA)

phospholipid binding (ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:23863933	PMID:29164996

Genomics

Comparative Map Data

Cptp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	171,757,181 - 171,761,271 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	171,757,181 - 171,761,266 (-)	Ensembl				GRCr8
mRatBN7.2	5	166,474,947 - 166,479,103 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	166,474,966 - 166,479,017 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	169,179,617 - 169,183,722 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	171,001,038 - 171,005,143 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	170,963,569 - 170,967,674 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	173,314,219 - 173,318,384 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	173,314,228 - 173,318,313 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	176,789,844 - 176,794,000 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	172,723,909 - 172,727,994 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	164,675,665 - 164,679,750 (-)	NCBI		Celera
RGSC_v3.1	5	172,734,403 - 172,738,489 (-)	NCBI
Cytogenetic Map	5	q36	NCBI

CPTP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	1,324,802 - 1,328,896 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	1,324,756 - 1,328,897 (+)	Ensembl			hg38	GRCh38
GRCh37	1	1,260,182 - 1,264,276 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	1,250,006 - 1,254,139 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	1,316,866 - 1,320,999 (-)	NCBI		Celera
Cytogenetic Map	1	p36.33	NCBI
HuRef	1	531,348 - 535,481 (+)	NCBI		HuRef
CHM1_1	1	1,247,171 - 1,251,304 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	756,387 - 760,481 (+)	NCBI		T2T-CHM13v2.0

Cptp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	155,949,180 - 155,953,897 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	155,949,180 - 155,953,897 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	155,864,723 - 155,869,440 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	155,864,723 - 155,869,440 (-)	Ensembl			mm10	GRCm38
MGSCv37	4	155,238,832 - 155,243,549 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	154,708,523 - 154,713,240 (-)	NCBI		MGSCv36	mm8
Celera	4	158,135,645 - 158,140,363 (-)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	87.66	NCBI

Cptp
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	9,475,520 - 9,478,925 (-)	Ensembl
ChiLan1.0	NW_004955486	9,475,520 - 9,478,925 (-)	NCBI	ChiLan1.0	ChiLan1.0

CPTP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	226,895,838 - 226,899,917 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	225,594,379 - 225,598,298 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	81,942 - 86,035 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	1,281,504 - 1,285,620 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	1,281,979 - 1,285,620 (+)	Ensembl			panPan2	panpan1.1

CPTP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	56,498,163 - 56,501,918 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	56,498,207 - 56,500,845 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	56,574,487 - 56,578,246 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	56,700,384 - 56,704,143 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	56,700,409 - 56,705,741 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	56,691,124 - 56,694,883 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	56,583,408 - 56,587,167 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	56,973,645 - 56,977,405 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cptp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	27,645,591 - 27,649,487 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936737	1,816,475 - 1,820,320 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936737	1,816,461 - 1,820,353 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CPTP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	6	63,607,991 - 63,612,325 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	58,106,067 - 58,110,399 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CPTP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	130,124,705 - 130,128,745 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	130,125,790 - 130,126,711 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666054	34,688,042 - 34,692,100 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cptp
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	8,283,926 - 8,287,274 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624818	8,283,925 - 8,287,410 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cptp
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	4,760,161 - 4,764,350 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	488
Count of miRNA genes:	253
Interacting mature miRNAs:	300
Transcripts:	ENSRNOT00000039117
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	130249266	172190305	Rat
1354583	Despr3	Despair related QTL3	4.98	0.0002	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	5	132930505	172190305	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	141212838	172190305	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	131708216	172190305	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	133789363	172190305	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	134369199	172190305	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136631198	172190305	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	156396728	172190305	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133081618	172190305	Rat
1581505	Rf54	Renal function QTL 54			kidney physiology trait (VT:0002136)	kidney 20-HETE level (CMO:0001854)	5	133270647	172190305	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	160071170	172129029	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	141764300	172190305	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133081618	172190305	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	133789363	172190305	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	148093485	172129029	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125969677	172190305	Rat

Markers in Region

RH129679

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	166,475,009 - 166,475,206 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	173,314,291 - 173,314,487	NCBI	Rnor6.0
Rnor_5.0	5	176,789,907 - 176,790,103	UniSTS	Rnor5.0
RGSC_v3.4	5	172,723,972 - 172,724,168	UniSTS	RGSC3.4
Celera	5	164,675,728 - 164,675,924	UniSTS
RH 3.4 Map	5	1175.0	UniSTS
Cytogenetic Map	5	q36	UniSTS

BF386962

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	166,475,504 - 166,475,694 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	173,314,786 - 173,314,975	NCBI	Rnor6.0
Rnor_5.0	5	176,790,402 - 176,790,591	UniSTS	Rnor5.0
RGSC_v3.4	5	172,724,467 - 172,724,656	UniSTS	RGSC3.4
Celera	5	164,676,223 - 164,676,412	UniSTS
RH 3.4 Map	5	1175.0	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	90	59	6	354	190	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001007703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001436897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001436898	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC126156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083599	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000039117 ⟹ ENSRNOP00000034006

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	171,757,181 - 171,761,266 (-)	Ensembl
mRatBN7.2 Ensembl	5	166,474,966 - 166,479,017 (-)	Ensembl
Rnor_6.0 Ensembl	5	173,314,228 - 173,318,313 (-)	Ensembl

RefSeq Acc Id:

NM_001007703 ⟹ NP_001007704

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	171,757,181 - 171,761,266 (-)	NCBI
mRatBN7.2	5	166,474,947 - 166,479,032 (-)	NCBI
Rnor_6.0	5	173,314,228 - 173,318,313 (-)	NCBI
Rnor_5.0	5	176,789,844 - 176,794,000 (-)	NCBI
RGSC_v3.4	5	172,723,909 - 172,727,994 (-)	RGD
Celera	5	164,675,665 - 164,679,750 (-)	RGD

Sequence:

show sequence

GGCTGGGCTTTAGGTGGCAGCTCAAGGTTTCTTCCCAACCGCAGGCTGCGAGCTTGGGGGAAAG
CATAGGGATGGGAGCTCTTACCTGACAGTGAACTAGGCAGCAGAGCCATGCCTCTGTAGACCAC
CGGAACGGAGGGCAAAGATTCGTCACCCACAGCAGCCTAATTATAGCTTTGATCAACCCCCCCC
ATCACTGACCTTCCCTGCACCCTTTGCCCTCCGCGGGAGTAAAGAACCACCACTCACCCCCCAC
CGGAACCCGTCTCAGTTCGTGTTGGAAGATGGATGGCCCAGAGAGAGATTTCAACCTTAAGGTT
GTCCTGATCAGCTTCAAGAAGTGTCTCACTGACAAGGGAGAGGTGCTGCTGGACCACTATACTG
CCAGCTGGAAGGGGCTTGTCAGGTTTCTGAACAGCCTAGGGGCTGTCTTTTCATTCATCTCCAA
GGATGTGGTCTCAAAGCTTCAGATTATGGAGCATCTGAGAAGTGGCCCACAGTCTGAACACTAC
ATTAGCTTGCAATCCATGGTAGCCTACGAGGTGAGCAACAAGCTGGTGGACAGAGACAGCCGCT
CACGTCCCCGACACCCTAACTCAGGCTGCCGGACTGTGCTGCGCCTACACCGTGCTCTGCATTG
GCTACAGCTGTTCCTGGAAGGCCTGCGCACCAGCTCTGAGGATGCTCGTACCTCCACCCTCTGC
AGTGAGGCCTACAATGCCACACTGGCTGCCTATCACTCCTGGATAGTACGTCAAGCTGTCAATG
TGGCCTTCCATGCCTTGCCCCCACGCAAGGTCTTCCTTGAGGCCATGAATATGGGGTCCTCTGA
GCAAGCAGTGGAGATGCTGGGAGAGGCCCTGCCCTTCATTGAGCAAGTGTATGACATCTCCCAG
AAGCTCTATGCTGAACATTCCCTGCTAGACCTGCCCTAGTAGTGGTAACCATACTGTGTGGACT
TCCCCTGCTCAGAACTGGGTTTGGGCAATCTAGGGCTACTCCCACAGCAGGGCTTTCTGGAAAC
TACTGTCACCCCTGTAAGCTGAACTGGTGGAAAGCCAGTCTGTGAAAAGAAAGGTCGTGGGCAG
CTGAACCAAGAAAGGTGAATGCTAGTCATCCTCTTGGTTCAGGATGAGACAGTTGAACTCCAGT
TTTGCCCTCCACTTCAGTCATGTGTTCAGTCAGGCTTGATTGAAGTGCAGATGGAAAATGGAGA
AGTGGGGGGCGGTGTCATGTATCTGCAACAACCCAAGGTTGCTCTACCTCTCCTGTATAGAATC
TGAAATGGTATAAGGACCCAGGACCCAGGAGCTGTCTTCCCTACAGCCAACATGCCCAGCCAAT
GTGTATCCTACATGTCTGGGGCCCCTTCATATTCCAAAAGCTGTAACATGGGTAACATGAAGTT
CCTCTGGCAGTGGCATGAGTCCCTGCCCTTCACCTGCTTCCTTGTTAGTCTCTCTGCATACCAA
ACAGGCCCTTGCCTCCTTGGAAATGGAAACTGTATGAAACCAATAGCTGAGGCTTCTCTAAGAA
AGCCTGCCCTGGTCAGTGCAGCCTGTTCCACAGCTTCTCCAGTATAGTACCGTCAGCCTTCTGA
AGGTGGCTTCTTACAACACATGTACCCCCAGGATTCTAAGATGTCAATACTAACTGGCCAAACC
ATACCTCTCTCTAGCCAGCCCTGCTGCTCCTGTTGCCATAATACGCAGATGACTTAGGACATGA
CTTGTGGGAGGAGACTAGGCCCCTTTGTCTGACAGATGGCCATACCTAGCATGGCTAATACCCA
GTGTATAAGACCATAAGCTTTCCCACTGGGTCTTAATGTTAAACCCGAGGACAATGCCCTCAGC
GTAGCTGATGTGTGCAAATGCAAACTTTGGGGGGCACATCTCTTTCCTTAAGAATTGTGATCTA
TGTATTTCCAACATAAATAAATTACACCTACATGATTGGGTATAGCACTCTGGAAAAAAAAAAA
AAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006239576 ⟹ XP_006239638

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	171,757,199 - 171,761,222 (-)	NCBI
mRatBN7.2	5	166,474,948 - 166,479,103 (-)	NCBI
Rnor_6.0	5	173,314,219 - 173,318,384 (-)	NCBI
Rnor_5.0	5	176,789,844 - 176,794,000 (-)	NCBI

Sequence:

show sequence

CCGATATGTCGAGTTCTAATTGGATGATCAGCAACCAATTGGGATGGCGTGGCAGCAAAGGGCG
GGGCAGAGGCTGGGCTTTAGGTGGCAGCTCAAGGTTTCTTCCCAACCGCAGGCTGCGAGCTTGG
GGGAAAGCATAGGGATGGGAGCTCTTACCTGACAGTGAACTAGGCAGCAGAGCCATGCCTCTGT
AGACCACCGGAACGGAGGGCAAAGATTCGTCACCCACAGCAGCCTAATTATAGCTTTGATCAAC
CCCCCCCATCACTGACCTTCCCTGCACCCTTTGCCCTCCGCGGGAGTAAAGAACCACCACTCAC
CCCCCACCGGAACCCGTCTCAGATCTTCTTCCCAATCACTTCCTGAGAAAATGAACCACAGAAT
GAGCTAATTCAGCATGGCGGCTACAAGTTCTGTGTGAAACTATTTCAGTTCGTGTTGGAAGATG
GATGGCCCAGAGAGAGATTTCAACCTTAAGGTTGTCCTGATCAGCTTCAAGAAGTGTCTCACTG
ACAAGGGAGAGGTGCTGCTGGACCACTATACTGCCAGCTGGAAGGGGCTTGTCAGGTTTCTGAA
CAGCCTAGGGGCTGTCTTTTCATTCATCTCCAAGGATGTGGTCTCAAAGCTTCAGATTATGGAG
CATCTGAGAAGTGGCCCACAGTCTGAACACTACATTAGCTTGCAATCCATGGTAGCCTACGAGG
TGAGCAACAAGCTGGTGGACAGAGACAGCCGCTCACGTCCCCGACACCCTAACTCAGGCTGCCG
GACTGTGCTGCGCCTACACCGTGCTCTGCATTGGCTACAGCTGTTCCTGGAAGGCCTGCGCACC
AGCTCTGAGGATGCTCGTACCTCCACCCTCTGCAGTGAGGCCTACAATGCCACACTGGCTGCCT
ATCACTCCTGGATAGTACGTCAAGCTGTCAATGTGGCCTTCCATGCCTTGCCCCCACGCAAGGT
CTTCCTTGAGGCCATGAATATGGGGTCCTCTGAGCAAGCAGTGGAGATGCTGGGAGAGGCCCTG
CCCTTCATTGAGCAAGTGTATGACATCTCCCAGAAGCTCTATGCTGAACATTCCCTGCTAGACC
TGCCCTAGTAGTGGTAACCATACTGTGTGGACTTCCCCTGCTCAGAACTGGGTTTGGGCAATCT
AGGGCTACTCCCACAGCAGGGCTTTCTGGAAACTACTGTCACCCCTGTAAGCTGAACTGGTGGA
AAGCCAGTCTGTGAAAAGAAAGGTCGTGGGCAGCTGAACCAAGAAAGGTGAATGCTAGTCATCC
TCTTGGTTCAGGATGAGACAGTTGAACTCCAGTTTTGCCCTCCACTTCAGTCATGTGTTCAGTC
AGGCTTGATTGAAGTGCAGATGGAAAATGGAGAAGTGGGGGGCGGTGTCATGTATCTGCAACAA
CCCAAGGTTGCTCTACCTCTCCTGTATAGAATCTGAAATGGTATAAGGACCCAGGACCCAGGAG
CTGTCTTCCCTACAGCCAACATGCCCAGCCAATGTGTATCCTACATGTCTGGGGCCCCTTCATA
TTCCAAAAGCTGTAACATGGGTAACATGAAGTTCCTCTGGCAGTGGCATGAGTCCCTGCCCTTC
ACCTGCTTCCTTGTTAGTCTCTCTGCATACCAAACAGGCCCTTGCCTCCTTGGAAATGGAAACT
GTATGAAACCAATAGCTGAGGCTTCTCTAAGAAAGCCTGCCCTGGTCAGTGCAGCCTGTTCCAC
AGCTTCTCCAGTATAGTACCGTCAGCCTTCTGAAGGTGGCTTCTTACAACACATGTACCCCCAG
GATTCTAAGATGTCAATACTAACTGGCCAAACCATACCTCTCTCTAGCCAGCCCTGCTGCTCCT
GTTGCCATAATACGCAGATGACTTAGGACATGACTTGTGGGAGGAGACTAGGCCCCTTTGTCTG
ACAGATGGCCATACCTAGCATGGCTAATACCCAGTGTATAAGACCATAAGCTTTCCCACTGGGT
CTTAATGTTAAACCCGAGGACAATGCCCTCAGCGTAGCTGATGTGTGCAAATGCAAACTTTGGG
GGGCACATCTCTTTCCTTAAGAATTGTGATCTATGTATTTCCAACATAAATAAATTACACCTAC
ATGATTGGGTATAGCACTCTGGGATGGGTCA

hide sequence

RefSeq Acc Id:

XM_039110121 ⟹ XP_038966049

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	171,757,199 - 171,761,271 (-)	NCBI
mRatBN7.2	5	166,474,948 - 166,479,037 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001007704	(Get FASTA)	NCBI Sequence Viewer
	NP_001423826	(Get FASTA)	NCBI Sequence Viewer
	NP_001423827	(Get FASTA)	NCBI Sequence Viewer
	XP_006239638	(Get FASTA)	NCBI Sequence Viewer
	XP_038966049	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83599	(Get FASTA)	NCBI Sequence Viewer
	EDL81338	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000034006
	ENSRNOP00000034006.3
GenBank Protein	Q5XIS2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001007704 ⟸ NM_001007703

- UniProtKB:

Q5XIS2 (UniProtKB/Swiss-Prot), A6IUT7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDGPERDFNLKVVLISFKKCLTDKGEVLLDHYTASWKGLVRFLNSLGAVFSFISKDVVSKLQIM
EHLRSGPQSEHYISLQSMVAYEVSNKLVDRDSRSRPRHPNSGCRTVLRLHRALHWLQLFLEGLR
TSSEDARTSTLCSEAYNATLAAYHSWIVRQAVNVAFHALPPRKVFLEAMNMGSSEQAVEMLGEA
LPFIEQVYDISQKLYAEHSLLDLP

hide sequence

RefSeq Acc Id:

XP_006239638 ⟸ XM_006239576

- Peptide Label:

isoform X1

- Sequence:

show sequence

MDGPERDFNLKVVLISFKKCLTDKGEVLLDHYTASWKGLVRFLNSLGAVFSFISKDVVSKLQIM
EHLRSGPQSEHYISLQSMVAYEVSNKLVDRDSRSRPRHPNSGCRTVLRLHRALHWLQLFLEGLR
TSSEDARTSTLCSEAYNATLAAYHSWIVRQAVNVAFHALPPRKVFLEAMNMGSSEQAVEMLGEA
LPFIEQVYDISQKLYAEHSLLDLP

hide sequence

Ensembl Acc Id:

ENSRNOP00000034006 ⟸ ENSRNOT00000039117

RefSeq Acc Id:	XP_038966049 ⟸ XM_039110121
- Peptide Label:	isoform X2

Protein Domains

Glycolipid transfer protein

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XIS2-F1-model_v2	AlphaFold	Q5XIS2	1-216	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694334

Promoter ID:

EPDNEW_R4859

Type:

initiation region

Name:

Cptp_1

Description:

ceramide-1-phosphate transfer protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	173,318,277 - 173,318,337	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359656	AgrOrtholog
BioCyc Gene	G2FUF-38891	BioCyc
Ensembl Genes	ENSRNOG00000022455	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000039117	ENTREZGENE
	ENSRNOT00000039117.4	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.3520.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7133008	IMAGE-MGC_LOAD
InterPro	GLTP_sf	UniProtKB/Swiss-Prot
	Glycolipid_transfer_prot_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:313771	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94339	IMAGE-MGC_LOAD
NCBI Gene	313771	ENTREZGENE
PANTHER	CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN	UniProtKB/Swiss-Prot
	GLYCOLIPID TRANSFER PROTEIN-RELATED	UniProtKB/Swiss-Prot
Pfam	GLTP	UniProtKB/Swiss-Prot
PhenoGen	Cptp	PhenoGen
RatGTEx	ENSRNOG00000022455	RatGTEx
Superfamily-SCOP	SSF110004	UniProtKB/Swiss-Prot
UniProt	A6IUT7	ENTREZGENE, UniProtKB/TrEMBL
	CPTP_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-07-09	Cptp	ceramide-1-phosphate transfer protein	Gltpd1	glycolipid transfer protein domain containing 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Gltpd1	glycolipid transfer protein domain containing 1	MGC94339	similar to BC002216 protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-29	MGC94339	similar to BC002216 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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