Gtf2f1 (general transcription factor IIF subunit 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Gtf2f1 (general transcription factor IIF subunit 1) Rattus norvegicus
Analyze
Symbol: Gtf2f1
Name: general transcription factor IIF subunit 1
RGD ID: 1359646
Description: Predicted to enable several functions, including RNA polymerase II general transcription initiation factor activity; TFIIF-class transcription factor complex binding activity; and promoter-specific chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cell junction and nucleoplasm. Predicted to be part of transcription factor TFIID complex and transcription factor TFIIF complex. Orthologous to human GTF2F1 (general transcription factor IIF subunit 1); PARTICIPATES IN RNA polymerase II transcription elongation pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: general transcription factor IIF, polypeptide 1; general transcription factor IIF, polypeptide 1, 74kDa; MGC94148; TFIIF-alpha; transcription initiation factor IIF subunit alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr891,931,033 - 1,940,197 (-)NCBIGRCr8
mRatBN7.291,844,027 - 1,853,455 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl91,843,901 - 1,853,423 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx92,277,798 - 2,286,963 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.097,627,157 - 7,636,322 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.096,583,019 - 6,592,184 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0910,032,806 - 10,042,392 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl910,033,011 - 10,042,418 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.099,033,464 - 9,043,042 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera96,664,214 - 6,673,260 (+)NCBICelera
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gtf2f1Ratmucolipidosis type IV  ISOGTF2F1 (Homo sapiens)8554872ClinVar Annotator: match by term: Mucolipidosis type IVClinVarPMID:11030752 more ...

1 to 20 of 82 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gtf2f1Rat17alpha-ethynylestradiol increases expressionISOGtf2f1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of GTF2F1 mRNACTDPMID:17942748
Gtf2f1Rat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of GTF2F1 mRNACTDPMID:29097150
Gtf2f1Rat17alpha-ethynylestradiol multiple interactionsISOGtf2f1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GTF2F1 mRNACTDPMID:17942748
Gtf2f1Rat17beta-estradiol increases expressionISOGtf2f1 (Mus musculus)6480464Estradiol results in increased expression of GTF2F1 mRNACTDPMID:39298647
Gtf2f1Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOGtf2f1 (Mus musculus)64804642 more ...CTDPMID:30294300
Gtf2f1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOGtf2f1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GTF2F1 mRNACTDPMID:17942748
Gtf2f1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOGtf2f1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of GTF2F1 mRNACTDPMID:21570461
Gtf2f1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of GTF2F1 mRNACTDPMID:22298810
Gtf2f1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of GTF2F1 mRNACTDPMID:16960034 and PMID:34747641
Gtf2f1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOGtf2f1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of GTF2F1 mRNACTDPMID:16960034
Gtf2f1Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of GTF2F1 mRNACTDPMID:21346803
Gtf2f1Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of GTF2F1 mRNACTDPMID:21346803
Gtf2f1Rat2-methylcholine affects expressionISOGTF2F1 (Homo sapiens)6480464beta-methylcholine affects the expression of GTF2F1 mRNACTDPMID:21179406
Gtf2f1Rat4,4'-sulfonyldiphenol increases expressionISOGtf2f1 (Mus musculus)6480464bisphenol S results in increased expression of GTF2F1 mRNACTDPMID:39298647
Gtf2f1Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of GTF2F1 mRNACTDPMID:36041667
Gtf2f1Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of GTF2F1 mRNACTDPMID:31881176
Gtf2f1Ratacrolein multiple interactionsISOGTF2F1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of GTF2F1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of GTF2F1 mRNACTDPMID:32699268
Gtf2f1Ratalpha-pinene multiple interactionsISOGTF2F1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of GTF2F1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of GTF2F1 mRNACTDPMID:32699268
Gtf2f1Ratantirheumatic drug decreases expressionISOGTF2F1 (Homo sapiens)6480464Antirheumatic Agents results in decreased expression of GTF2F1 mRNACTDPMID:24449571
Gtf2f1Rataristolochic acid A increases expressionISOGTF2F1 (Homo sapiens)6480464aristolochic acid I results in increased expression of GTF2F1 mRNACTDPMID:33212167

1 to 20 of 82 rows

Biological Process
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gtf2f1Ratpositive regulation of transcription by RNA polymerase II  IDA 632949 RGD 
Gtf2f1Ratpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Ratpositive regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISOGtf2f1 (Mus musculus)1624291 PMID:9265625RGDPMID:9265625
Gtf2f1Ratpositive regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIEAUniProtKB:Q3THK3 and ensembl:ENSMUSP000000027331600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Ratpositive regulation of transcription by RNA polymerase II involved_inISOGTF2F1 (Homo sapiens)1624291 PMID:15351637 and PMID:8662660RGDPMID:15351637 and PMID:8662660
Gtf2f1Ratpositive regulation of transcription elongation by RNA polymerase II involved_inIEAInterPro:IPR0088511600115GO_REF:0000002InterProGO_REF:0000002
Gtf2f1Ratresponse to virus involved_inISOGTF2F1 (Homo sapiens)1624291 PMID:16548883RGDPMID:16548883
Gtf2f1Ratresponse to virus involved_inIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Rattranscription elongation by RNA polymerase II involved_inISOGTF2F1 (Homo sapiens)1624291 PMID:15351637RGDPMID:15351637
Gtf2f1Rattranscription elongation by RNA polymerase II involved_inIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Rattranscription initiation at RNA polymerase II promoter involved_inIEAInterPro:IPR008851 and InterPro:IPR0110391600115GO_REF:0000002InterProGO_REF:0000002
Gtf2f1Rattranscription initiation at RNA polymerase II promoter involved_inIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Rattranscription initiation at RNA polymerase II promoter involved_inIBAFB:FBgn0010282 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gtf2f1Rattranscription initiation at RNA polymerase II promoter involved_inISOGTF2F1 (Homo sapiens)1624291 PMID:15351637 and PMID:7929273RGDPMID:15351637 and PMID:7929273
1 to 14 of 14 rows

Cellular Component
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gtf2f1Ratcell junction located_inIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Ratcell junction located_inISOGTF2F1 (Homo sapiens)1624291 RGDGO_REF:0000052
Gtf2f1Ratintracellular membrane-bounded organelle located_inISOGTF2F1 (Homo sapiens)1624291 RGDGO_REF:0000052
Gtf2f1Ratintracellular membrane-bounded organelle located_inIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Ratnucleoplasm located_inISOGTF2F1 (Homo sapiens)1624291 RGDGO_REF:0000052
Gtf2f1Ratnucleoplasm located_inIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Gtf2f1Ratnucleus located_inIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Ratnucleus located_inIEAInterPro:IPR0088511600115GO_REF:0000002InterProGO_REF:0000002
Gtf2f1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Gtf2f1Ratnucleus located_inISOGTF2F1 (Homo sapiens)1624291 PMID:15723517RGDPMID:15723517
Gtf2f1Ratprotein-containing complex part_ofISOGTF2F1 (Homo sapiens)1624291 PMID:12732728RGDPMID:12732728
Gtf2f1Ratprotein-containing complex part_ofIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Rattranscription factor TFIID complex part_ofISOGTF2F1 (Homo sapiens)1624291 PMID:27193682RGDPMID:27193682
Gtf2f1Rattranscription factor TFIID complex part_ofIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Rattranscription factor TFIIF complex part_ofISOGTF2F1 (Homo sapiens)1624291 PMID:11183778RGDPMID:11183778
Gtf2f1Rattranscription factor TFIIF complex part_ofIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Rattranscription factor TFIIF complex part_ofIBAFB:FBgn0010282 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 18 of 18 rows

Molecular Function
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gtf2f1RatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
Gtf2f1RatDNA binding enablesIEAInterPro:IPR0088511600115GO_REF:0000002InterProGO_REF:0000002
Gtf2f1Ratphosphatase activator activity enablesISOGTF2F1 (Homo sapiens)1624291 PMID:12721286RGDPMID:12721286
Gtf2f1Ratphosphatase activator activity enablesIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Ratpromoter-specific chromatin binding enablesISSUniProtKB:P352691600115GO_REF:0000024UniProtGO_REF:0000024
Gtf2f1Ratpromoter-specific chromatin binding enablesIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Ratpromoter-specific chromatin binding enablesISOGTF2F1 (Homo sapiens)1624291 PMID:24441171RGDPMID:24441171
Gtf2f1Ratprotein binding  IPIPsmc2 (Rattus norvegicus)9681443 RGD 
Gtf2f1Ratprotein binding enablesISOGtf2f1 (Mus musculus)1624291PR:Q03358 PMID:9265625RGDPMID:9265625
Gtf2f1Ratprotein binding enablesISOGTF2F1 (Homo sapiens)1624291UniProtKB:O94763 more ...RGDPMID:11183778 more ...
Gtf2f1Ratprotein domain specific binding enablesISOGTF2F1 (Homo sapiens)1624291UniProtKB:Q9Y5B0 and PMID:15723517RGDPMID:15723517
Gtf2f1Ratprotein domain specific binding enablesIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1Ratprotein phosphatase binding enablesISOGTF2F1 (Homo sapiens)1624291UniProtKB:Q9Y5B0 and PMID:12732728RGDPMID:12732728
Gtf2f1Ratprotein phosphatase binding enablesIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1RatRNA polymerase II general transcription initiation factor activity enablesISOGTF2F1 (Homo sapiens)1624291 PMID:27193682 and PMID:7929273RGDPMID:27193682 and PMID:7929273
Gtf2f1RatRNA polymerase II general transcription initiation factor activity enablesIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1RatRNA polymerase II general transcription initiation factor activity enablesIBAPANTHER:PTN000313913 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gtf2f1RatRNA polymerase II general transcription initiation factor binding enablesISOGTF2F1 (Homo sapiens)1624291UniProtKB:P21675 and PMID:8625415RGDPMID:8625415
Gtf2f1RatRNA polymerase II general transcription initiation factor binding enablesIEAUniProtKB:P35269 and ensembl:ENSP000003779691600115GO_REF:0000107EnsemblGO_REF:0000107
Gtf2f1RatTFIIF-class transcription factor complex binding enablesIBAFB:FBgn0010282 and PANTHER:PTN0003139131600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 20 of 20 rows

RGD Manual Annotations


  

1 to 12 of 12 rows
#
Reference Title
Reference Citation
1. A cDNA encoding RAP74, a general initiation factor for transcription by RNA polymerase II. Finkelstein A, etal., Nature 1992 Jan 30;355(6359):464-7.
2. The carboxyl terminus of RAP30 is similar in sequence to region 4 of bacterial sigma factors and is required for function. Garrett KP, etal., J Biol Chem 1992 Nov 25;267(33):23942-9.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Structural insights into transcription initiation by RNA polymerase II. Grunberg S and Hahn S, Trends Biochem Sci. 2013 Dec;38(12):603-11. doi: 10.1016/j.tibs.2013.09.002. Epub 2013 Oct 11.
5. Control of transcriptional elongation. Kwak H and Lis JT, Annu Rev Genet. 2013;47:483-508. doi: 10.1146/annurev-genet-110711-155440. Epub 2013 Sep 11.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. Tissue and cell distribution of a mammalian proteasomal ATPase, MSS1, and its complex formation with the basal transcription factors. Yanagi S, etal., Biochem Biophys Res Commun. 2000 Dec 20;279(2):568-73.
1 to 12 of 12 rows
PMID:8625415   PMID:8662660   PMID:9265625   PMID:12721286   PMID:12732728   PMID:15489334   PMID:15723517   PMID:16548883   PMID:16854843   PMID:22658674   PMID:22681889   PMID:24441171  
PMID:27193682  



Gtf2f1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr891,931,033 - 1,940,197 (-)NCBIGRCr8
mRatBN7.291,844,027 - 1,853,455 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl91,843,901 - 1,853,423 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx92,277,798 - 2,286,963 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.097,627,157 - 7,636,322 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.096,583,019 - 6,592,184 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0910,032,806 - 10,042,392 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl910,033,011 - 10,042,418 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.099,033,464 - 9,043,042 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera96,664,214 - 6,673,260 (+)NCBICelera
Cytogenetic Map9q11NCBI
GTF2F1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38196,379,572 - 6,393,164 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl196,379,572 - 6,393,981 (-)EnsemblGRCh38hg38GRCh38
GRCh37196,379,583 - 6,393,175 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36196,330,580 - 6,344,291 (-)NCBINCBI36Build 36hg18NCBI36
Build 34196,330,580 - 6,344,184NCBI
Celera196,318,367 - 6,332,078 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef196,139,725 - 6,153,437 (-)NCBIHuRef
CHM1_1196,379,205 - 6,392,915 (-)NCBICHM1_1
T2T-CHM13v2.0196,368,474 - 6,382,065 (-)NCBIT2T-CHM13v2.0
Gtf2f1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391757,310,402 - 57,318,398 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1757,310,405 - 57,318,288 (-)EnsemblGRCm39 Ensembl
GRCm381757,003,401 - 57,011,394 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1757,003,405 - 57,011,288 (-)EnsemblGRCm38mm10GRCm38
MGSCv371757,142,825 - 57,150,711 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361756,688,526 - 56,696,417 (-)NCBIMGSCv36mm8
Celera1761,351,328 - 61,359,214 (-)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.62NCBI
Gtf2f1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554953,208,733 - 3,217,163 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554953,208,334 - 3,217,460 (+)NCBIChiLan1.0ChiLan1.0
GTF2F1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22010,780,235 - 10,794,718 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11910,006,147 - 10,020,634 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0195,401,090 - 5,414,142 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1196,323,259 - 6,336,812 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl196,323,780 - 6,336,215 (-)Ensemblpanpan1.1panPan2
GTF2F1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12053,771,201 - 53,780,646 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2053,771,325 - 53,780,644 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2053,518,020 - 53,527,557 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02054,425,381 - 54,434,910 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2054,425,568 - 54,434,910 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12053,491,833 - 53,501,378 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02053,940,180 - 53,949,728 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02054,169,704 - 54,179,458 (+)NCBIUU_Cfam_GSD_1.0
Gtf2f1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118214,084,208 - 214,095,837 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365883,742,921 - 3,750,196 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365883,742,880 - 3,750,400 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF2F1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl272,687,790 - 72,698,270 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1272,687,612 - 72,698,274 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2273,200,976 - 73,211,779 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GTF2F1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.165,996,585 - 6,006,893 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660812,012,088 - 2,027,210 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtf2f1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248283,513,027 - 3,521,650 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248283,512,990 - 3,521,848 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Gtf2f1
25 total Variants

Predicted Target Of
Summary Value
Count of predictions:64
Count of miRNA genes:58
Interacting mature miRNAs:62
Transcripts:ENSRNOT00000073683
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat

1 to 10 of 12 rows
RH126039  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.291,844,038 - 1,844,255 (-)MAPPERmRatBN7.2
Rnor_6.0910,042,164 - 10,042,380NCBIRnor6.0
Rnor_5.099,042,814 - 9,043,030UniSTSRnor5.0
Celera96,673,034 - 6,673,250UniSTS
Cytogenetic Map9q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000073683   ⟹   ENSRNOP00000064830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl91,843,901 - 1,853,346 (-)Ensembl
Rnor_6.0 Ensembl910,033,011 - 10,042,418 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100918   ⟹   ENSRNOP00000076645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl91,844,031 - 1,852,076 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101330   ⟹   ENSRNOP00000084850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl91,843,901 - 1,853,423 (-)Ensembl
RefSeq Acc Id: NM_001007711   ⟹   NP_001007712
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr891,931,033 - 1,940,197 (-)NCBI
mRatBN7.291,844,029 - 1,853,195 (-)NCBI
Rnor_6.0910,033,028 - 10,042,390 (+)NCBI
Rnor_5.099,033,464 - 9,043,042 (+)NCBI
Celera96,664,214 - 6,673,260 (+)RGD
Sequence:
Protein RefSeqs NP_001007712 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79136 (Get FASTA)   NCBI Sequence Viewer  
  EDL83591 (Get FASTA)   NCBI Sequence Viewer  
  EDL83592 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064830
  ENSRNOP00000064830.1
GenBank Protein Q6AY96 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001007712   ⟸   NM_001007711
- UniProtKB: Q6AY96 (UniProtKB/Swiss-Prot),   A0A8I5Y917 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064830   ⟸   ENSRNOT00000073683
Ensembl Acc Id: ENSRNOP00000084850   ⟸   ENSRNOT00000101330
Ensembl Acc Id: ENSRNOP00000076645   ⟸   ENSRNOT00000100918

Name Modeler Protein Id AA Range Protein Structure
AF-Q6AY96-F1-model_v2 AlphaFold Q6AY96 1-508 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696443
Promoter ID:EPDNEW_R6968
Type:initiation region
Name:Gtf2f1_1
Description:general transcription factor IIF subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0910,033,000 - 10,033,060EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-28497 BioCyc
Ensembl Genes ENSRNOG00000047134 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000073683 ENTREZGENE
  ENSRNOT00000073683.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7127699 IMAGE-MGC_LOAD
InterPro TFIIF-alpha UniProtKB/Swiss-Prot
  TFIIF_interaction UniProtKB/Swiss-Prot
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
  WH_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report rno:316123 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94148 IMAGE-MGC_LOAD
NCBI Gene 316123 ENTREZGENE
PANTHER GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1 UniProtKB/Swiss-Prot
  PTHR13011 UniProtKB/Swiss-Prot
Pfam TFIIF_alpha UniProtKB/Swiss-Prot
PhenoGen Gtf2f1 PhenoGen
RatGTEx ENSRNOG00000047134 RatGTEx
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot
  SSF50916 UniProtKB/Swiss-Prot
UniProt A0A8I5Y917 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A212_RAT UniProtKB/TrEMBL
  A6KQT3_RAT UniProtKB/TrEMBL
  A6KQT4_RAT UniProtKB/TrEMBL
  Q6AY96 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Gtf2f1  general transcription factor IIF subunit 1  Gtf2f1  general transcription factor IIF, polypeptide 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Gtf2f1  general transcription factor IIF, polypeptide 1    general transcription factor IIF, polypeptide 1, 74kDa  Name updated 1299863 APPROVED
2005-07-29 Gtf2f1  general transcription factor IIF, polypeptide 1, 74kDa      Symbol and Name status set to provisional 70820 PROVISIONAL