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Gene: Igsf5 (immunoglobulin superfamily, member 5) Rattus norvegicus

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Symbol:

Igsf5

Name:

immunoglobulin superfamily, member 5

RGD ID:

1359642

Description:

Predicted to enable PDZ domain binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in anchoring junction and apical plasma membrane. Predicted to be active in bicellular tight junction and cell surface. Orthologous to human IGSF5 (immunoglobulin superfamily member 5); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cell adhesion molecule JCAM; immunoglobulin superfamily member 5; JAM-4; Jam4; junctional adhesion molecule 4; LOC304000

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	49,155,990 - 49,198,872 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	49,156,341 - 49,210,603 (+)	Ensembl				GRCr8
mRatBN7.2	11	35,686,513 - 35,729,396 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	35,686,705 - 35,741,129 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	44,337,555 - 44,379,045 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	37,008,927 - 37,050,415 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	36,161,291 - 36,203,722 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	36,736,580 - 36,779,614 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	36,736,586 - 36,779,615 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	40,264,840 - 40,305,321 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	36,698,885 - 36,755,559 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	32,750,117 - 32,790,934 (-)	NCBI		Celera
RGSC_v3.1	11	36,756,473 - 36,813,146 (+)	NCBI
Cytogenetic Map	11	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Prostatic Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1,1-trichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (EXP)

benzo[a]pyrene (ISO)

Benzo[ghi]perylene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

cobalt dichloride (EXP)

diethyl phthalate (EXP)

dorsomorphin (ISO)

endosulfan (EXP)

flutamide (EXP)

genistein (ISO)

maneb (ISO)

methylmercury chloride (ISO)

nefazodone (EXP)

nitrofen (EXP)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell-cell adhesion (IBA,ISO)

Cellular Component

apical plasma membrane (IEA)

bicellular tight junction (IBA,IEA,ISO)

cell surface (IBA,ISO)

Molecular Function

PDZ domain binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1.	Hirabayashi S, etal., Mol Cell Biol 2003 Jun;23(12):4267-82.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:16118391	PMID:16832352

Genomics

Comparative Map Data

Igsf5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	49,155,990 - 49,198,872 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	49,156,341 - 49,210,603 (+)	Ensembl				GRCr8
mRatBN7.2	11	35,686,513 - 35,729,396 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	35,686,705 - 35,741,129 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	44,337,555 - 44,379,045 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	37,008,927 - 37,050,415 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	36,161,291 - 36,203,722 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	36,736,580 - 36,779,614 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	36,736,586 - 36,779,615 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	40,264,840 - 40,305,321 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	36,698,885 - 36,755,559 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	32,750,117 - 32,790,934 (-)	NCBI		Celera
RGSC_v3.1	11	36,756,473 - 36,813,146 (+)	NCBI
Cytogenetic Map	11	q11	NCBI

IGSF5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	39,711,771 - 39,802,081 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	39,745,183 - 39,802,081 (+)	Ensembl			hg38	GRCh38
GRCh37	21	41,117,110 - 41,174,008 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	40,039,204 - 40,095,893 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	21	26,314,757 - 26,371,484 (+)	NCBI		Celera
Cytogenetic Map	21	q22.2	NCBI
HuRef	21	26,586,615 - 26,643,328 (+)	NCBI		HuRef
CHM1_1	21	40,678,069 - 40,734,791 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	21	38,096,241 - 38,186,566 (+)	NCBI		T2T-CHM13v2.0

Igsf5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	96,162,676 - 96,266,772 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	96,162,868 - 96,223,321 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	16	96,361,479 - 96,465,572 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	96,361,668 - 96,422,121 (+)	Ensembl			mm10	GRCm38
MGSCv37	16	96,583,364 - 96,643,728 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	16	96,466,704 - 96,508,938 (+)	NCBI		MGSCv36	mm8
Celera	16	97,438,053 - 97,498,945 (+)	NCBI		Celera
Cytogenetic Map	16	C4	NCBI
cM Map	16	56.93	NCBI

Igsf5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	38,468,816 - 38,512,243 (+)	Ensembl
ChiLan1.0	NW_004955407	38,468,873 - 38,510,040 (+)	NCBI	ChiLan1.0	ChiLan1.0

IGSF5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	35,701,263 - 35,902,111 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	30,557,376 - 30,758,128 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	26,079,931 - 26,157,483 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	21	39,435,321 - 39,491,196 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

IGSF5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	34,438,959 - 34,482,869 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	31	34,442,719 - 34,482,142 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	33,716,206 - 33,760,110 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	33,951,242 - 33,995,344 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	33,954,973 - 33,994,947 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	33,822,278 - 33,864,850 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	33,827,115 - 33,870,991 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	34,319,272 - 34,363,166 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Igsf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	33,911,941 - 33,939,814 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936500	3,519,224 - 3,553,071 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936500	3,518,884 - 3,553,071 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IGSF5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	13	203,325,385 - 203,372,361 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	213,445,798 - 213,493,257 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IGSF5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	83,671,466 - 83,695,487 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	83,694,619 - 83,732,133 (+)	NCBI		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
ChlSab1.1 Ensembl	2	83,694,619 - 83,732,133 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666054	11,524,249 - 11,582,822 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Igsf5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624745	24,280,360 - 24,330,509 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Igsf5
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	48,266,315 - 48,304,200 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Igsf5
166 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	62
Count of miRNA genes:	49
Interacting mature miRNAs:	58
Transcripts:	ENSRNOT00000032566
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	22524746	82951192	Rat
1598841	Memor7	Memory QTL 7			exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	11	33306008	78306008	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	46443168	91443168	Rat
1598811	Bp291	Blood pressure QTL 291	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	33306008	78306008	Rat
634339	Niddm50	Non-insulin dependent diabetes mellitus QTL 50	3.32		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	10806125	55806125	Rat
634341	Bw121	Body weight QTL 121	3.56		abdominal fat pad mass (VT:1000711)	abdominal fat pad weight (CMO:0000088)	11	35323199	55805892	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	36749459	81749459	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	32943067	89836615	Rat
724517	Uae18	Urinary albumin excretion QTL 18	3.7		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	29958996	57754989	Rat
2290451	Scl58	Serum cholesterol level QTL 58	3.48		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	11	26318031	55806125	Rat
1300130	Rf20	Renal function QTL 20	4.44		kidney glomerulus integrity trait (VT:0010546)	kidney glomerulus diameter (CMO:0001166)	11	31915469	76915469	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	36428416	81428416	Rat
1600394	Edcs1	Endometrial carcinoma susceptibility QTL1	2.9	0.04	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	11	12823152	57823152	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	34618760	79618760	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	20193549	96351019	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	36749459	81749459	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	36749459	81749459	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	36749459	81749459	Rat
631510	Spl2	Serum phospholipid level QTL 2	4.1		blood phospholipid amount (VT:0006084)	serum phospholipid level (CMO:0001171)	11	27556685	72556685	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	6	17	98	90	90	59	30	59	6	228	66	82	81	90	31	7	7

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001006990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437774	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437777	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270559	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC142238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY325233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY439284	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC086342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC097947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000032566 ⟹ ENSRNOP00000032595

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	49,156,341 - 49,198,870 (+)	Ensembl
mRatBN7.2 Ensembl	11	35,686,967 - 35,729,386 (+)	Ensembl
Rnor_6.0 Ensembl	11	36,737,022 - 36,779,604 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000082098 ⟹ ENSRNOP00000069224

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	49,156,341 - 49,210,603 (+)	Ensembl
mRatBN7.2 Ensembl	11	35,686,705 - 35,741,129 (+)	Ensembl
Rnor_6.0 Ensembl	11	36,736,586 - 36,779,615 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085014 ⟹ ENSRNOP00000070929

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	49,163,322 - 49,198,213 (+)	Ensembl
mRatBN7.2 Ensembl	11	35,693,846 - 35,728,737 (+)	Ensembl
Rnor_6.0 Ensembl	11	36,743,901 - 36,778,948 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100325 ⟹ ENSRNOP00000084327

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	49,156,396 - 49,198,870 (+)	Ensembl
mRatBN7.2 Ensembl	11	35,693,846 - 35,728,737 (+)	Ensembl

RefSeq Acc Id:

NM_001006990 ⟹ NP_001006991

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	49,156,443 - 49,198,872 (+)	NCBI
mRatBN7.2	11	35,686,967 - 35,729,396 (+)	NCBI
Rnor_6.0	11	36,737,022 - 36,779,614 (+)	NCBI
Rnor_5.0	11	40,264,840 - 40,305,321 (+)	NCBI
RGSC_v3.4	11	36,698,885 - 36,755,559 (+)	RGD
Celera	11	32,750,117 - 32,790,934 (-)	RGD

Sequence:

show sequence

GCTAGGGCTCTGCCGGGATTCAGAGGAGGGTCTCAGGGTCCGGAAGCTAGGAAAGCTGTCTTCA
TTTCTTAGACAAACTTGTAAATGCCCTCTCCCTTGAAGAGAAACTTCATGGGGACCAGGGTGTT
CCGTTGCCACTGGGGATTCTGAGAGGGCAGATTACAAGAGGTCTGTCCAAGTGAGGAGGCAGGT
CCTGGTCAGTGAGGAGTCAGGATTCTAGTGAGAGAGAAGACCCCAGTGAAGACGGGCACCATGG
CGGCGAGGAAACAGTTCTGAAGGCAGGTGCACGGATTCCAAGGTGTAGCAGAAGTGCTGGGATT
GAAGGAAGCCCCCGGCTCAGAGGTAAGGAAGATCATGCTGAGATGGAGGGCAGCTGGAGAGATG
TCCTGGCTGTGCTGGTCATCCTGGCTCAGTTGACAGTTTCCGGATCCAGTTATCAGATCATAGA
AGGTCCTCGGAATGTAACAGCCCTAAAGGGCTCGGAGGCTCGCTTCAACTGCACTGTGACTCAT
GGCTGGAAGCTTATCATGTGGGCTCTCAACGGTATCGTGGAGCTGAGTCTCACCTCCCAGAAAC
CCATCATCACCAGCAACCGCTTCACCTCTGCCAGCTACAACAGTACTGACAGCTTCATCTCTGA
GATGATCATCCACAATGTACAGCTCAACGACTCGGGGCCCGTGCAATGTAGCCTGCAGAACAGC
AATGTGTTTGGATTCGCCTTTCTCTCGGTGCAAGTCATGGGGACTCTGAACATTCCTAGCAGCA
ACCTTATAGTCACTGAGGGTGAGCCCTGTAACGTGACTTGCTATGCCGTGGGCTGGACCCCACT
CCCGAATATTTCCTGGGAGCTTGAGGTTCCTGTAAGTCATTCAAGCTACTATTCCTTTCTGGAG
CCGGGCAACTCTCTGAGGGTCTTGAGTGTCCTGGATCTCACACCACTGGGCAACGGGACCTTGA
CTTGTGTGGCAGAGATGAAGGACTTGCAGGCCAGCGAGTCCTTAACTGTCAACCTGACTGTGGT
TCAGCCTCCACCGGACAGTATTGGCGGGGAAGGCCAAGCGCTGCCAACCTGGGCCATCATCCTC
CTGGCAGTGGCCTTTTCCTTACTCTTGATCCTGATCATTGCTCTGATTATAATATTCTGTTGCT
GTTGTGTCTCCAGGAGAGAAAAGGAAGAATCTACTTATCAAAATGAAATAAGGAAATCTGCAAA
TGTGAGGACAGGCAAAGCAGATCCCGAGACATGGTTAAAAAGTGGGAAGGAAAACTATGGGTAC
AAATCGGATGAAGCAAGGGCTGCACAAATTGCTTCTCTCCCTCCTAAATCTGGTGAAGTTAGCC
TTCCAGAACAACGCAGTAGCCTTCCTCAACAGGAACTTGATAAACATCGGCCCAGCCCAGTGAC
TCATCCACGAGTTTCCTTTGACATCGCCAGTCCTCAGAAGATCAGAAATGTGACTATAGTGTAA
TAATAAAGACTTCTCATGGCTGTGCTTGGTGTACACACACCGGGTCAATATCATTCTCTTCTGT
ATCCTGAGACCGCATCTCAGCTTTGCCAAAGAGGCCGCATCAGAGTCACCAGAGCTGGTGTTTT
ATAGCAACAGGAGGAGTTGGTTTTCCTCCTTCCAAGAAGAATTTGATCTTGAGGTGTATCATGG
TTTTGGTGAATTCCTTAAGGTGACCGAGTAAAACATGAGGGTCTGTCATGGTGACATTCCTCAT
GACTTGACACTCCTGCTAACCCAGCGAAAGGCAGATATAGATCCTGCCACGACCTTCAGAATGC
TTCTGTTTTCTGAGATCGTGGTAATATGGTCTTTATGTGTGTTTCACAGCGAGGGACATCACTG
AACCTTATTACAGAACCAAGAGCCTAACAACTAGCATCAACTGTGTCTTGTAAGTAACTGGCCC
CTGGAGCTCAGGAATGCAACAAGAGGAGAAGCAACGCACATGTCCGGATGCTTTCCAGAAGACA
GTCTTTCGCATACGCTCCCTTGTCCTTGTCACCATGGTTTTGGGTGAATTAGGTGTTGGATTCT
GCCTGATGAGGGACAAAGCTCATGTTCCGCCAGCATCATGAACGAACGGGGAAGAGATATATAC
TATTTAATAAACAATCAAAAAGCCAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006248155 ⟹ XP_006248217

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	49,155,994 - 49,198,872 (+)	NCBI
mRatBN7.2	11	35,686,519 - 35,729,396 (+)	NCBI
Rnor_6.0	11	36,736,580 - 36,779,614 (+)	NCBI
Rnor_5.0	11	40,264,840 - 40,305,321 (+)	NCBI

Sequence:

show sequence

GAAAGTTGCTGCAGCTAGGGGCGCTTACACCTGTCTGTTCCTCCAGGTTTATAGCCTGGGCACT
GACTGGATAGGGCCACTTGGCAAGGGACTTCCTGTTACCGGGTGGGGAGTGTCCTATCAGAAGT
GTTCCTGTGTTTCTATAGAGAGCAGCAAGAAGCCAGGAAGCCCCGTGTGAATGAGATTCAGAGA
TTTACCTGCCTGAGGTAAGGAAGATCATGCTGAGATGGAGGGCAGCTGGAGAGATGTCCTGGCT
GTGCTGGTCATCCTGGCTCAGTTGACAGTTTCCGGATCCAGTTATCAGATCATAGAAGGTCCTC
GGAATGTAACAGCCCTAAAGGGCTCGGAGGCTCGCTTCAACTGCACTGTGACTCATGGCTGGAA
GCTTATCATGTGGGCTCTCAACGGTATCGTGGAGCTGAGTCTCACCTCCCAGAAACCCATCATC
ACCAGCAACCGCTTCACCTCTGCCAGCTACAACAGTACTGACAGCTTCATCTCTGAGATGATCA
TCCACAATGTACAGCTCAACGACTCGGGGCCCGTGCAATGTAGCCTGCAGAACAGCAATGTGTT
TGGATTCGCCTTTCTCTCGGTGCAAGTCATGGGGACTCTGAACATTCCTAGCAGCAACCTTATA
GTCACTGAGGGTGAGCCCTGTAACGTGACTTGCTATGCCGTGGGCTGGACCCCACTCCCGAATA
TTTCCTGGGAGCTTGAGGTTCCTGTAAGTCATTCAAGCTACTATTCCTTTCTGGAGCCGGGCAA
CTCTCTGAGGGTCTTGAGTGTCCTGGATCTCACACCACTGGGCAACGGGACCTTGACTTGTGTG
GCAGAGATGAAGGACTTGCAGGCCAGCGAGTCCTTAACTGTCAACCTGACTGTGGTTCAGCCTC
CACCGGACAGTATTGGCGGGGAAGGCCAAGCGCTGCCAACCTGGGCCATCATCCTCCTGGCAGT
GGCCTTTTCCTTACTCTTGATCCTGATCATTGCTCTGATTATAATATTCTGTTGCTGTTGTGTC
TCCAGGAGAGAAAAGGAAGAATCTACTTATCAAAATGAAATAAGGAAATCTGCAAATGTGAGGA
CAGGCAAAGCAGATCCCGAGACATGGTTAAAAAGTGGGAAGGAAAACTATGGGTACAAATCGGA
TGAAGCAAGGGCTGCACAAATTGCTTCTCTCCCTCCTAAATCTGGTGAAGTTAGCCTTCCAGAA
CAACGCAGTAGCCTTCCTCAACAGGAACTTGATAAACATCGGCCCAGCCCAGTGACTCATCCAC
GAGTTTCCTTTGACATCGCCAGTCCTCAGAAGATCAGAAATGTGACTATAGTGTAATAATAAAG
ACTTCTCATGGCTGTGCTTGGTGTACACACACCGGGTCAATATCATTCTCTTCTGTATCCTGAG
ACCGCATCTCAGCTTTGCCAAAGAGGCCGCATCAGAGTCACCAGAGCTGGTGTTTTATAGCAAC
AGGAGGAGTTGGTTTTCCTCCTTCCAAGAAGAATTTGATCTTGAGGTGTATCATGGTTTTGGTG
AATTCCTTAAGGTGACCGAGTAAAACATGAGGGTCTGTCATGGTGACATTCCTCATGACTTGAC
ACTCCTGCTAACCCAGCGAAAGGCAGATATAGATCCTGCCACGACCTTCAGAATGCTTCTGTTT
TCTGAGATCGTGGTAATATGGTCTTTATGTGTGTTTCACAGCGAGGGACATCACTGAACCTTAT
TACAGAACCAAGAGCCTAACAACTAGCATCAACTGTGTCTTGTAAGTAACTGGCCCCTGGAGCT
CAGGAATGCAACAAGAGGAGAAGCAACGCACATGTCCGGATGCTTTCCAGAAGACAGTCTTTCG
CATACGCTCCCTTGTCCTTGTCACCATGGTTTTGGGTGAATTAGGTGTTGGATTCTGCCTGATG
AGGGACAAAGCTCATGTTCCGCCAGCATCATGAACGAACGGGGAAGAGATATATACTATTTAAT
AAACAATCAAAAAGCCAA

hide sequence

RefSeq Acc Id:

XM_006248156 ⟹ XP_006248218

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	49,155,990 - 49,198,872 (+)	NCBI
mRatBN7.2	11	35,686,515 - 35,729,396 (+)	NCBI
Rnor_6.0	11	36,736,581 - 36,779,614 (+)	NCBI
Rnor_5.0	11	40,264,840 - 40,305,321 (+)	NCBI

Sequence:

show sequence

AAAGTTGCTGCAGCTAGGGGCGCTTACACCTGTCTGTTCCTCCAGGTTTATAGCCTGGGCACTG
ACTGGATAGGGCCACTTGGCAAGGGACTTCCTGTTACCGGGTGGGGAGTGTCCTATCAGAAGTG
TTCCTGTGTTTCTATAGAGAGCAGCAAGAAGCCAGGAAGCCCCGTGTGAATGAGATTCAGAGAT
TTACCTGCCTGAGGTAAGGAAGATCATGCTGAGATGGAGGGCAGCTGGAGAGATGTCCTGGCTG
TGCTGGTCATCCTGGCTCAGTTGACAGTTTCCGGATCCAGTTATCAGATCATAGAAGGTCCTCG
GAATGTAACAGCCCTAAAGGGCTCGGAGGCTCGCTTCAACTGCACTGTGACTCATGGCTGGAAG
CTTATCATGTGGGCTCTCAACGGTATCGTGGAGCTGAGTCTCACCTCCCAGAAACCCATCATCA
CCAGCAACCGCTTCACCTCTGCCAGCTACAACAGTACTGACAGCTTCATCTCTGAGATGATCAT
CCACAATGTACAGCTCAACGACTCGGGGCCCGTGCAATGTAGCCTGCAGAACAGCAATGTGTTT
GGATTCGCCTTTCTCTCGGTGCAAGACAGTATTGGCGGGGAAGGCCAAGCGCTGCCAACCTGGG
CCATCATCCTCCTGGCAGTGGCCTTTTCCTTACTCTTGATCCTGATCATTGCTCTGATTATAAT
ATTCTGTTGCTGTTGTGTCTCCAGGAGAGAAAAGGAAGAATCTACTTATCAAAATGAAATAAGG
AAATCTGCAAATGTGAGGACAGGCAAAGCAGATCCCGAGACATGGTTAAAAAGTGGGAAGGAAA
ACTATGGGTACAAATCGGATGAAGCAAGGGCTGCACAAATTGCTTCTCTCCCTCCTAAATCTGG
TGAAGTTAGCCTTCCAGAACAACGCAGTAGCCTTCCTCAACAGGAACTTGATAAACATCGGCCC
AGCCCAGTGACTCATCCACGAGTTTCCTTTGACATCGCCAGTCCTCAGAAGATCAGAAATGTGA
CTATAGTGTAATAATAAAGACTTCTCATGGCTGTGCTTGGTGTACACACACCGGGTCAATATCA
TTCTCTTCTGTATCCTGAGACCGCATCTCAGCTTTGCCAAAGAGGCCGCATCAGAGTCACCAGA
GCTGGTGTTTTATAGCAACAGGAGGAGTTGGTTTTCCTCCTTCCAAGAAGAATTTGATCTTGAG
GTGTATCATGGTTTTGGTGAATTCCTTAAGGTGACCGAGTAAAACATGAGGGTCTGTCATGGTG
ACATTCCTCATGACTTGACACTCCTGCTAACCCAGCGAAAGGCAGATATAGATCCTGCCACGAC
CTTCAGAATGCTTCTGTTTTCTGAGATCGTGGTAATATGGTCTTTATGTGTGTTTCACAGCGAG
GGACATCACTGAACCTTATTACAGAACCAAGAGCCTAACAACTAGCATCAACTGTGTCTTGTAA
GTAACTGGCCCCTGGAGCTCAGGAATGCAACAAGAGGAGAAGCAACGCACATGTCCGGATGCTT
TCCAGAAGACAGTCTTTCGCATACGCTCCCTTGTCCTTGTCACCATGGTTTTGGGTGAATTAGG
TGTTGGATTCTGCCTGATGAGGGACAAAGCTCATGTTCCGCCAGCATCATGAACGAACGGGGAA
GAGATATATACTATTTAATAAACAATCAAAAAGCCAA

hide sequence

RefSeq Acc Id:

XM_039088368 ⟹ XP_038944296

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	49,155,990 - 49,198,872 (+)	NCBI
mRatBN7.2	11	35,686,513 - 35,729,396 (+)	NCBI

RefSeq Acc Id:

XM_063270559 ⟹ XP_063126629

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	49,156,386 - 49,198,872 (+)	NCBI

RefSeq Acc Id:

XM_063270560 ⟹ XP_063126630

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	49,156,386 - 49,198,872 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001006991	(Get FASTA)	NCBI Sequence Viewer
	NP_001424702	(Get FASTA)	NCBI Sequence Viewer
	NP_001424703	(Get FASTA)	NCBI Sequence Viewer
	NP_001424704	(Get FASTA)	NCBI Sequence Viewer
	NP_001424705	(Get FASTA)	NCBI Sequence Viewer
	NP_001424706	(Get FASTA)	NCBI Sequence Viewer
	XP_006248217	(Get FASTA)	NCBI Sequence Viewer
	XP_006248218	(Get FASTA)	NCBI Sequence Viewer
	XP_038944296	(Get FASTA)	NCBI Sequence Viewer
	XP_063126629	(Get FASTA)	NCBI Sequence Viewer
	XP_063126630	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97947	(Get FASTA)	NCBI Sequence Viewer
	AAP92634	(Get FASTA)	NCBI Sequence Viewer
	AAR99701	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032595
	ENSRNOP00000032595.4
	ENSRNOP00000084327
GenBank Protein	Q5VJ70	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001006991 ⟸ NM_001006990
- Peptide Label:	precursor
- UniProtKB:	Q5VJ70 (UniProtKB/Swiss-Prot), A0A8L2R0R2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEGSWRDVLAVLVILAQLTVSGSSYQIIEGPRNVTALKGSEARFNCTVTHGWKLIMWALNGIVE LSLTSQKPIITSNRFTSASYNSTDSFISEMIIHNVQLNDSGPVQCSLQNSNVFGFAFLSVQVMG TLNIPSSNLIVTEGEPCNVTCYAVGWTPLPNISWELEVPVSHSSYYSFLEPGNSLRVLSVLDLT PLGNGTLTCVAEMKDLQASESLTVNLTVVQPPPDSIGGEGQALPTWAIILLAVAFSLLLILIIA LIIIFCCCCVSRREKEESTYQNEIRKSANVRTGKADPETWLKSGKENYGYKSDEARAAQIASLP PKSGEVSLPEQRSSLPQQELDKHRPSPVTHPRVSFDIASPQKIRNVTIV hide sequence

RefSeq Acc Id:

XP_006248217 ⟸ XM_006248155

- Peptide Label:

isoform X1

- Sequence:

show sequence

MEGSWRDVLAVLVILAQLTVSGSSYQIIEGPRNVTALKGSEARFNCTVTHGWKLIMWALNGIVE
LSLTSQKPIITSNRFTSASYNSTDSFISEMIIHNVQLNDSGPVQCSLQNSNVFGFAFLSVQVMG
TLNIPSSNLIVTEGEPCNVTCYAVGWTPLPNISWELEVPVSHSSYYSFLEPGNSLRVLSVLDLT
PLGNGTLTCVAEMKDLQASESLTVNLTVVQPPPDSIGGEGQALPTWAIILLAVAFSLLLILIIA
LIIIFCCCCVSRREKEESTYQNEIRKSANVRTGKADPETWLKSGKENYGYKSDEARAAQIASLP
PKSGEVSLPEQRSSLPQQELDKHRPSPVTHPRVSFDIASPQKIRNVTIV

hide sequence

RefSeq Acc Id:

XP_006248218 ⟸ XM_006248156

- Peptide Label:

isoform X2

- Sequence:

show sequence

MEGSWRDVLAVLVILAQLTVSGSSYQIIEGPRNVTALKGSEARFNCTVTHGWKLIMWALNGIVE
LSLTSQKPIITSNRFTSASYNSTDSFISEMIIHNVQLNDSGPVQCSLQNSNVFGFAFLSVQDSI
GGEGQALPTWAIILLAVAFSLLLILIIALIIIFCCCCVSRREKEESTYQNEIRKSANVRTGKAD
PETWLKSGKENYGYKSDEARAAQIASLPPKSGEVSLPEQRSSLPQQELDKHRPSPVTHPRVSFD
IASPQKIRNVTIV

hide sequence

Ensembl Acc Id:

ENSRNOP00000069224 ⟸ ENSRNOT00000082098

Ensembl Acc Id:

ENSRNOP00000070929 ⟸ ENSRNOT00000085014

Ensembl Acc Id:

ENSRNOP00000032595 ⟸ ENSRNOT00000032566

RefSeq Acc Id:	XP_038944296 ⟸ XM_039088368
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000084327 ⟸ ENSRNOT00000100325

RefSeq Acc Id:	XP_063126629 ⟸ XM_063270559
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063126630 ⟸ XM_063270560
- Peptide Label:	isoform X3

Protein Domains

Ig-like Ig-like V-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5VJ70-F1-model_v2	AlphaFold	Q5VJ70	1-369	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698089

Promoter ID:

EPDNEW_R8613

Type:

initiation region

Name:

Igsf5_1

Description:

immunoglobulin superfamily, member 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R8614

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	36,736,702 - 36,736,762	EPDNEW

RGD ID:

13698090

Promoter ID:

EPDNEW_R8614

Type:

multiple initiation site

Name:

Igsf5_2

Description:

immunoglobulin superfamily, member 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R8613

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	36,736,980 - 36,737,040	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359642	AgrOrtholog
BioCyc Gene	G2FUF-21704	BioCyc
Ensembl Genes	ENSRNOG00000028216	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000032566	ENTREZGENE
	ENSRNOT00000032566.7	UniProtKB/Swiss-Prot
	ENSRNOT00000100325	ENTREZGENE
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7301824	IMAGE-MGC_LOAD
	IMAGE:7373302	IMAGE-MGC_LOAD
InterPro	Ig-like_dom	UniProtKB/Swiss-Prot
	Ig-like_dom_sf	UniProtKB/Swiss-Prot
	Ig-like_fold	UniProtKB/Swiss-Prot
	Ig_sub	UniProtKB/Swiss-Prot
KEGG Report	rno:304000	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105523	IMAGE-MGC_LOAD
	MGC:116070	IMAGE-MGC_LOAD
NCBI Gene	304000	ENTREZGENE
PANTHER	IMMUNOGLOBULIN SUPERFAMILY MEMBER 5	UniProtKB/Swiss-Prot
	PTHR44991	UniProtKB/Swiss-Prot
PhenoGen	Igsf5	PhenoGen
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000028216	RatGTEx
SMART	SM00409	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZZA6_RAT	UniProtKB/TrEMBL
	A0A8L2R0R2	ENTREZGENE, UniProtKB/TrEMBL
	IGSF5_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q7TP22_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-09-17	Igsf5	immunoglobulin superfamily, member 5	LOC304000	cell adhesion molecule JCAM	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-29	LOC304000	cell adhesion molecule JCAM			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD