Pelo (pelota mRNA surveillance and ribosome rescue factor) - Rat Genome Database

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Gene: Pelo (pelota mRNA surveillance and ribosome rescue factor) Rattus norvegicus
Analyze
Symbol: Pelo
Name: pelota mRNA surveillance and ribosome rescue factor
RGD ID: 1359591
Description: Predicted to enable ribosome binding activity and stalled ribosome sensor activity. Predicted to be involved in nonfunctional rRNA decay; nuclear-transcribed mRNA catabolic process, no-go decay; and rescue of stalled ribosome. Predicted to act upstream of or within several processes, including inner cell mass cell proliferation; mesenchymal to epithelial transition; and positive regulation of BMP signaling pathway. Predicted to be part of Dom34-Hbs1 complex. Predicted to be active in cytosolic ribosome. Orthologous to human PELO (pelota mRNA surveillance and ribosome rescue factor); PARTICIPATES IN translation termination pathway; mRNA decay pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC94455; pelota homolog; pelota homolog (Drosophila)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8248,530,902 - 48,532,670 (-)NCBIGRCr8
mRatBN7.2246,797,853 - 46,799,621 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl246,797,853 - 46,799,746 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx253,898,237 - 53,900,005 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0251,957,441 - 51,959,209 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0246,827,651 - 46,829,417 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0247,266,758 - 47,268,526 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl247,266,738 - 47,268,625 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0271,808,491 - 71,810,259 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4245,900,723 - 45,902,491 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1245,828,956 - 45,830,724 (-)NCBI
Celera242,545,596 - 42,547,364 (-)NCBICelera
Cytogenetic Map2q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(S)-colchicine  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
acrylamide  (ISO)
adenine  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
hydroxyurea  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
mitomycin C  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (ISO)
nimesulide  (EXP)
oxaliplatin  (EXP)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Disruption of the pelota gene causes early embryonic lethality and defects in cell cycle progression. Adham IM, etal., Mol Cell Biol 2003 Feb;23(4):1470-6.
2. Structural view on recycling of archaeal and eukaryotic ribosomes after canonical termination and ribosome rescue. Franckenberg S, etal., Curr Opin Struct Biol. 2012 Dec;22(6):786-96. doi: 10.1016/j.sbi.2012.08.002. Epub 2012 Sep 29.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:24835669  


Genomics

Comparative Map Data
Pelo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8248,530,902 - 48,532,670 (-)NCBIGRCr8
mRatBN7.2246,797,853 - 46,799,621 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl246,797,853 - 46,799,746 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx253,898,237 - 53,900,005 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0251,957,441 - 51,959,209 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0246,827,651 - 46,829,417 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0247,266,758 - 47,268,526 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl247,266,738 - 47,268,625 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0271,808,491 - 71,810,259 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4245,900,723 - 45,902,491 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1245,828,956 - 45,830,724 (-)NCBI
Celera242,545,596 - 42,547,364 (-)NCBICelera
Cytogenetic Map2q14NCBI
PELO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38552,787,916 - 52,804,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl552,787,916 - 52,804,044 (+)EnsemblGRCh38hg38GRCh38
GRCh37552,083,750 - 52,099,878 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36552,119,531 - 52,134,208 (+)NCBINCBI36Build 36hg18NCBI36
Build 34552,119,530 - 52,134,206NCBI
Celera549,037,324 - 49,052,004 (+)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef549,055,620 - 49,070,302 (+)NCBIHuRef
CHM1_1552,086,424 - 52,101,104 (+)NCBICHM1_1
T2T-CHM13v2.0553,615,621 - 53,631,750 (+)NCBIT2T-CHM13v2.0
Pelo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913115,224,891 - 115,226,694 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13115,224,891 - 115,226,722 (-)EnsemblGRCm39 Ensembl
GRCm3813115,088,355 - 115,090,158 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13115,088,355 - 115,090,186 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713115,878,563 - 115,880,366 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613116,209,242 - 116,211,703 (-)NCBIMGSCv36mm8
Celera13119,447,710 - 119,449,318 (-)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1364.61NCBI
Pelo
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544614,564,366 - 14,566,178 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544614,564,366 - 14,566,178 (-)NCBIChiLan1.0ChiLan1.0
PELO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2461,140,900 - 61,158,121 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1559,297,530 - 59,307,873 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0561,229,841 - 61,247,565 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1562,851,499 - 62,865,786 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl562,851,099 - 62,865,786 (-)Ensemblpanpan1.1panPan2
PELO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1462,440,923 - 62,443,598 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha462,216,402 - 62,218,376 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0462,939,633 - 62,941,473 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl462,791,553 - 62,953,332 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1462,714,001 - 62,716,979 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0462,831,158 - 62,834,996 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0463,366,543 - 63,368,230 (-)NCBIUU_Cfam_GSD_1.0
Pelo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213205,642,223 - 205,644,180 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648014,577,381 - 14,582,144 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648014,578,718 - 14,580,690 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PELO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1632,142,034 - 32,148,287 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11632,130,254 - 32,146,114 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21633,953,117 - 33,955,102 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PELO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1449,094,330 - 49,097,545 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl449,094,528 - 49,100,838 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660822,036,319 - 2,040,892 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pelo
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247596,525,418 - 6,527,322 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247596,525,529 - 6,527,320 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pelo
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:28
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000032223
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)243162366111362592Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)238573329122609194Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24317101783575226Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)24280460760653831Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
12879863Bp402Blood pressure QTL 4020.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24112578956532139Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22238462767384627Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
10755434Coatc7Coat color QTL 70.04794coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23064806575648065Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1300160Hrtrt3Heart rate QTL 33.62heart pumping trait (VT:2000009)absolute change in heart rate (CMO:0000534)22997159351729300Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
9685065Swd6Spike wave discharge measurement QTL 65.80.01brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge rate (CMO:0001739)23922393748793699Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat
1643006Pain1Pain QTL 13.630.005mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)22699957148268661Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)228484589169504100Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)228484589169504100Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat

Markers in Region
RH130277  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2246,797,854 - 46,798,034 (+)MAPPERmRatBN7.2
Rnor_6.0247,266,760 - 47,266,939NCBIRnor6.0
Rnor_5.0271,808,493 - 71,808,672UniSTSRnor5.0
RGSC_v3.4245,900,725 - 45,900,904UniSTSRGSC3.4
Celera242,545,598 - 42,545,777UniSTS
RH 3.4 Map2307.3UniSTS
Cytogenetic Map2q14UniSTS
Cytogenetic Map2q16-q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000091499   ⟹   ENSRNOP00000075562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl246,797,853 - 46,799,746 (-)Ensembl
Rnor_6.0 Ensembl247,266,738 - 47,268,625 (-)Ensembl
RefSeq Acc Id: NM_001007634   ⟹   NP_001007635
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8248,530,902 - 48,532,670 (-)NCBI
mRatBN7.2246,797,853 - 46,799,621 (-)NCBI
Rnor_6.0247,266,758 - 47,268,526 (-)NCBI
Rnor_5.0271,808,491 - 71,810,259 (-)NCBI
RGSC_v3.4245,900,723 - 45,902,491 (-)RGD
Celera242,545,596 - 42,547,364 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001007635 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH83637 (Get FASTA)   NCBI Sequence Viewer  
  EDM10393 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075562.1
  ENSRNOP00055008056
  ENSRNOP00060019120
  ENSRNOP00065027580
GenBank Protein Q5XIP1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001007635   ⟸   NM_001007634
- UniProtKB: Q5XIP1 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075562   ⟸   ENSRNOT00000091499
Protein Domains
eRF1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIP1-F1-model_v2 AlphaFold Q5XIP1 1-385 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691150
Promoter ID:EPDNEW_R1674
Type:initiation region
Name:Pelo_1
Description:pelota mRNA surveillance and ribosome rescue factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0247,268,614 - 47,268,674EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359591 AgrOrtholog
BioCyc Gene G2FUF-54323 BioCyc
Ensembl Genes ENSRNOG00000061128 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055006386 UniProtKB/Swiss-Prot
  ENSRNOG00060014022 UniProtKB/Swiss-Prot
  ENSRNOG00065020386 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000091499.2 UniProtKB/Swiss-Prot
  ENSRNOT00055010380 UniProtKB/Swiss-Prot
  ENSRNOT00060023998 UniProtKB/Swiss-Prot
  ENSRNOT00065034431 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.30.870 UniProtKB/Swiss-Prot
  3.30.1330.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.420.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7134766 IMAGE-MGC_LOAD
InterPro eFR1_2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  eRF1_1_Pelota UniProtKB/Swiss-Prot
  eRF1_2 UniProtKB/Swiss-Prot
  eRF1_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  L30e-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pelota/DOM34_N UniProtKB/Swiss-Prot
  Transl-rel_pelota UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:294754 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94455 IMAGE-MGC_LOAD
NCBI Gene 294754 ENTREZGENE
PANTHER PELOTA UniProtKB/TrEMBL
  PROTEIN PELOTA HOMOLOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10853 UniProtKB/Swiss-Prot
Pfam eRF1_1 UniProtKB/Swiss-Prot
  eRF1_2 UniProtKB/Swiss-Prot
  eRF1_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pelo PhenoGen
RatGTEx ENSRNOG00000061128 RatGTEx
  ENSRNOG00055006386 RatGTEx
  ENSRNOG00060014022 RatGTEx
  ENSRNOG00065020386 RatGTEx
SMART eRF1_1 UniProtKB/Swiss-Prot
Superfamily-SCOP L30e-like UniProtKB/TrEMBL
  SSF159065 UniProtKB/Swiss-Prot
  SSF55315 UniProtKB/Swiss-Prot
  Translational machinery components UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6I5T5_RAT UniProtKB/TrEMBL
  PELO_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-20 Pelo  pelota mRNA surveillance and ribosome rescue factor  Pelo  pelota homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Pelo  pelota homolog (Drosophila)  Pelo  pelota homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 Pelo  pelota homolog      Symbol and Name status set to provisional 70820 PROVISIONAL