Hsd17b13 (hydroxysteroid (17-beta) dehydrogenase 13)

Gene: Hsd17b13 (hydroxysteroid (17-beta) dehydrogenase 13) Rattus norvegicus

Analyze

Symbol:

Hsd17b13

Name:

hydroxysteroid (17-beta) dehydrogenase 13

RGD ID:

1359553

Description:

Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and steroid dehydrogenase activity. Predicted to be involved in lipid metabolic process. Predicted to act upstream of or within positive regulation of lipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in lipid droplet. Orthologous to human HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

17-beta hydroxysteroid dehydrogenase 13; 17-beta-HSD 13; 17-beta-hydroxysteroid dehydrogenase 13; hepatic retinol/retinal dehydrogenase; MGC108860; short-chain dehydrogenase/reductase 9

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Hsd17b13 (hydroxysteroid (17-beta) dehydrogenase 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hsd17b13 (hydroxysteroid 17-beta dehydrogenase 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hsd17b13 (hydroxysteroid 17-beta dehydrogenase 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hsd17b13 (hydroxysteroid 17-beta dehydrogenase 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HSD17B11 (hydroxysteroid 17-beta dehydrogenase 11)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Hsd17b13 (hydroxysteroid (17-beta) dehydrogenase 13)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YDL114W	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG9265	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	synj2bp	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	hsd17b13	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	hsd17b11	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	6,056,708 - 6,071,463 (+)	NCBI		GRCr8
mRatBN7.2	14	5,751,697 - 5,766,809 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	5,752,132 - 5,768,166 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	5,720,997 - 5,735,669 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	7,021,227 - 7,035,909 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	5,719,659 - 5,734,100 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	7,113,544 - 7,128,218 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	7,113,544 - 7,128,218 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	7,103,692 - 7,118,366 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	6,901,197 - 6,915,871 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	6,901,196 - 6,915,871 (+)	NCBI
Celera	14	5,892,024 - 5,906,128 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant polycystic kidney disease (ISO)

genetic disease (ISO)

steatotic liver disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (EXP)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

ciguatoxin CTX1B (ISO)

clofibric acid (EXP)

Cuprizon (EXP)

decabromodiphenyl ether (EXP)

diuron (EXP)

enilconazole (ISO)

entacapone (EXP)

fipronil (ISO)

flutamide (EXP)

glyphosate (ISO)

Heliotrine (EXP)

Lasiocarpine (EXP)

leflunomide (EXP)

N,N-diethyl-m-toluamide (ISO)

N-nitrosodiethylamine (EXP)

NAD zwitterion (ISO)

NAD(+) (ISO)

nickel dichloride (EXP)

nimesulide (EXP)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

permethrin (ISO)

pirinixic acid (EXP)

potassium dichromate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

rotenone (EXP)

sodium arsenite (ISO)

sodium dichromate (EXP)

Soman (EXP)

tetrachloroethene (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

tolcapone (EXP)

trichloroethene (EXP,ISO)

triphenyl phosphate (ISO)

tris(2-chloroethyl) phosphate (ISO)

troglitazone (ISO)

valdecoxib (EXP)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid metabolic process (IEA)

positive regulation of lipid biosynthetic process (IEA,ISO)

Cellular Component

endoplasmic reticulum (IEA)

lipid droplet (IBA,IEA,ISO,ISS)

Molecular Function

all-trans-retinol dehydrogenase (NAD+) activity (IEA)

estradiol 17-beta-dehydrogenase [NAD(P)] activity (IEA)

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (IBA,IEA)

protein binding (ISO)

steroid dehydrogenase activity (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	null	JRS Domain-based curation
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:18359291	PMID:25028495

Genomics

Comparative Map Data

Hsd17b13
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	6,056,708 - 6,071,463 (+)	NCBI		GRCr8
mRatBN7.2	14	5,751,697 - 5,766,809 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	5,752,132 - 5,768,166 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	5,720,997 - 5,735,669 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	7,021,227 - 7,035,909 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	5,719,659 - 5,734,100 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	7,113,544 - 7,128,218 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	7,113,544 - 7,128,218 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	7,103,692 - 7,118,366 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	6,901,197 - 6,915,871 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	6,901,196 - 6,915,871 (+)	NCBI
Celera	14	5,892,024 - 5,906,128 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

HSD17B13
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	87,303,794 - 87,322,882 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	87,303,789 - 87,322,886 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	88,224,946 - 88,244,034 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	88,443,965 - 88,463,062 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	88,582,119 - 88,601,217	NCBI
Celera	4	85,513,757 - 85,532,909 (-)	NCBI		Celera
Cytogenetic Map	4	q22.1	NCBI
HuRef	4	83,970,650 - 83,989,809 (-)	NCBI		HuRef
CHM1_1	4	88,202,022 - 88,221,156 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	90,632,830 - 90,651,922 (-)	NCBI		T2T-CHM13v2.0

Hsd17b13
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	104,103,308 - 104,125,254 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	104,103,306 - 104,125,276 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	103,955,442 - 103,977,388 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	103,955,440 - 103,977,410 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	104,384,461 - 104,406,407 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	104,195,744 - 104,217,666 (-)	NCBI		MGSCv36	mm8
Celera	5	101,262,064 - 101,284,149 (-)	NCBI		Celera
Cytogenetic Map	5	E5	NCBI
cM Map	5	50.46	NCBI

Hsd17b13
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955474	2,532,213 - 2,555,260 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955474	2,532,213 - 2,554,324 (+)	NCBI	ChiLan1.0	ChiLan1.0

HSD17B13
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	85,320,330 - 85,340,053 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	85,582,387 - 85,602,146 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	79,606,163 - 79,625,401 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	90,333,816 - 90,351,346 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	90,333,816 - 90,351,346 (-)	Ensembl	panpan1.1		panPan2

HSD17B13
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	10,793,211 - 10,813,785 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	10,794,617 - 10,854,193 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	31,140,526 - 31,160,493 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	10,845,726 - 10,865,737 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	10,845,726 - 10,906,673 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	10,926,962 - 10,946,969 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	10,754,978 - 10,774,991 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	29,180,080 - 29,200,062 (+)	NCBI		UU_Cfam_GSD_1.0

Hsd17b13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	2,277,466 - 2,329,764 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936896	698,254 - 709,550 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936896	657,443 - 709,735 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HSD17B13
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	35,683,556 - 35,702,439 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	35,682,130 - 35,702,216 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	14,381,279 - 14,399,658 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hsd17b13
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624872	3,844,220 - 3,865,342 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624872	3,844,903 - 3,865,337 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Hsd17b13
182 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	39
Count of miRNA genes:	38
Interacting mature miRNAs:	38
Transcripts:	ENSRNOT00000038188
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300159	Bmd61	Bone mineral density QTL 61	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
2300183	Bmd60	Bone mineral density QTL 60	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
619619	Rf4	Renal disease susceptibility QTL 4	4.1	0.002	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	14	1	32754612	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41131407	Rat
71115	Niddm15	Non-insulin dependent diabetes mellitus QTL 15	4.8		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1217606	11030812	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1217606	16960180	Rat
724541	Niddm53	Non-insulin dependent diabetes mellitus QTL 53		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	3813074	9088978	Rat
2293089	Iddm31	Insulin dependent diabetes mellitus QTL 31	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	3813074	18274691	Rat
2293089	Iddm31	Insulin dependent diabetes mellitus QTL 31	4.7		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	14	3813074	18274691	Rat
1300114	Srn2	Serum renin concentration QTL 2	3.27		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	3813074	21217635	Rat
70195	Mcs8	Mammary carcinoma susceptibility QTL 8	4.28		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	14	3813074	24531477	Rat
1331740	Bw26	Body weight QTL 26	3.028		body mass (VT:0001259)	body weight (CMO:0000012)	14	3813074	30767156	Rat

Markers in Region

RH139738

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	5,766,474 - 5,766,693 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	7,127,887 - 7,128,105	NCBI	Rnor6.0
Rnor_5.0	14	7,118,035 - 7,118,253	UniSTS	Rnor5.0
RGSC_v3.4	14	6,915,540 - 6,915,758	UniSTS	RGSC3.4
Celera	14	5,905,797 - 5,906,015	UniSTS
RH 3.4 Map	14	114.1	UniSTS
Cytogenetic Map	14	p22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			31	31		31					1
Low	3	39	25	10	18	10	7	9	55	35	39	11	7
Below cutoff		4	1		1		1	2	19		1		1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001009684	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492928	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC122637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218851	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000038188 ⟹ ENSRNOP00000029333

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	5,752,132 - 5,766,806 (+)	Ensembl
Rnor_6.0 Ensembl	14	7,113,544 - 7,128,218 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000103301 ⟹ ENSRNOP00000097499

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	5,752,132 - 5,768,166 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000112563 ⟹ ENSRNOP00000081986

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	5,752,202 - 5,766,806 (+)	Ensembl

RefSeq Acc Id:

NM_001009684 ⟹ NP_001009684

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	6,056,789 - 6,071,463 (+)	NCBI
mRatBN7.2	14	5,752,132 - 5,766,806 (+)	NCBI
Rnor_6.0	14	7,113,544 - 7,128,218 (+)	NCBI
Rnor_5.0	14	7,103,692 - 7,118,366 (+)	NCBI
RGSC_v3.4	14	6,901,197 - 6,915,871 (+)	RGD
Celera	14	5,892,024 - 5,906,128 (+)	RGD

Sequence:

show sequence

TCTCTGTGGAGCTCCGTGCGGGGGCATCTGCTAGGAGAACAGAGTCCAAGGGAGAGAGCAGCTC
AGAGCCATGAACCTCATCCTGGAGCTTCTCTTGCTGGTGGGCATCATCATCTACTCCTACCTGG
AGTCACTGGTAAAGTTCTTCATTCCCCAGAGAAGAAAGTCTGTGGCCGGACAGACTGTTCTCAT
CACAGGAGCTGGACACGGAATAGGCAGGCTGACGGCTTATGAATTTGCAAAGCAGAAAAGCAGA
TTGGTCCTGTGGGATATTAGTAAGCACGGTGTTGAGGAAACCGCAGCCAAATGCAGGAAACTGG
GGGCTGTCGTGCACGTGTTTGTGGTGGACTGCAGCAACCGGGCAGAGATTTACAAGTCTGTGGA
TCAGGTAAAGAAAGAAGTTGGTGACATAGAGATTGTGGTAAACAACGCTGGGGCAATTTATCCA
GCCGACCTTCTTAGCACCAAGGATGAGGAGATCACCAAGACCTTCGAGGTCAACATCCTAGGAC
ATTTTTGGATCATAAAAGCACTCCTTCCATCGATGCTGAGAAGAAACTCTGGCCACATTGTCAC
AGTGGCTTCAGTGTGTGGCCACAGAGTGATTCCTTATCTCATCCCATATTGCTCCAGCAAGTTC
GCTGCTGTGGGCTTCCACAGAGCACTGACTGCAGAACTGGACACCTTGGGGAAAACCGGTATCA
AAACCTCCTGTCTCTGCCCTGTGTTCGTGAATACTGGCTTCACCAAAAACCCAAGTACCAGGTT
ATGGCCTGTGTTAGAGCCGGATGAAGTTGCAAGGAGTCTGATCGATGGGATACTTACCAACAAG
AAAATGATCTTCGTTCCGTCCTATATCAATATCTCTCTAATAGTGGAAATGTTTTTTCCTGAAC
GTGTCTTAAAAGCTATAAACCGTATACAGAATATTCAGTTTGAAGCGATTGTGGGCCACAGAAC
CAAGAGGAAGTAACATCTTGCGTGCAGAGACGTGTGGACGCCAATGACGCGAAGCCAAGTTTAG
AGCGGACGCGAGGCTTTCTTTCGCCCGTTTTAGAAGTGTTCCTTGTGTTTAAAATGTAGGTTTG
GCCCTAGTAGCCATCGAGCAAACGAGAGTGGTCAACTGTCCTTCTGGTTTCTTATACTTAAACT
CTCAGCCCCTGGTATTGGGTTCTGGAAATGGAGCTGTAGTAAGACAATGCCTGTCGCACAGCCG
AGTGAAAAGTCATTTGGTGTGTTTTTACTAAACAGAAATGTGGGAGAAAGGGTAAGACAATAAA
ATCTTGGACAAATGCTGAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XR_005492928

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	6,056,708 - 6,071,080 (+)	NCBI
mRatBN7.2	14	5,751,697 - 5,766,809 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001009684	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88191	(Get FASTA)	NCBI Sequence Viewer
	EDL99511	(Get FASTA)	NCBI Sequence Viewer
	EDL99512	(Get FASTA)	NCBI Sequence Viewer
	EDL99513	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000029333
	ENSRNOP00000029333.2
	ENSRNOP00000081986.1
	ENSRNOP00000097499.1
	ENSRNOP00055037103
	ENSRNOP00060014217
GenBank Protein	Q5M875	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001009684 ⟸ NM_001009684
- Peptide Label:	precursor
- UniProtKB:	Q5M875 (UniProtKB/Swiss-Prot), A0A8I5ZU34 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNLILELLLLVGIIIYSYLESLVKFFIPQRRKSVAGQTVLITGAGHGIGRLTAYEFAKQKSRLV LWDISKHGVEETAAKCRKLGAVVHVFVVDCSNRAEIYKSVDQVKKEVGDIEIVVNNAGAIYPAD LLSTKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHRVIPYLIPYCSSKFAA VGFHRALTAELDTLGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLEPDEVARSLIDGILTNKKM IFVPSYINISLIVEMFFPERVLKAINRIQNIQFEAIVGHRTKRK hide sequence

RefSeq Acc Id:

ENSRNOP00000029333 ⟸ ENSRNOT00000038188

RefSeq Acc Id:

ENSRNOP00000097499 ⟸ ENSRNOT00000103301

RefSeq Acc Id:

ENSRNOP00000081986 ⟸ ENSRNOT00000112563

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5M875-F1-model_v2	AlphaFold	Q5M875	1-300	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699179

Promoter ID:

EPDNEW_R9703

Type:

multiple initiation site

Name:

Hsd17b13_1

Description:

hydroxysteroid (17-beta) dehydrogenase 13

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	7,113,529 - 7,113,589	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359553	AgrOrtholog
BioCyc Gene	G2FUF-16495	BioCyc
Ensembl Genes	ENSRNOG00000002212	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055026205	UniProtKB/Swiss-Prot
	ENSRNOG00060010776	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000038188	ENTREZGENE
	ENSRNOT00000038188.3	UniProtKB/Swiss-Prot
	ENSRNOT00000103301.1	UniProtKB/TrEMBL
	ENSRNOT00000112563.1	UniProtKB/TrEMBL
	ENSRNOT00055045252	UniProtKB/Swiss-Prot
	ENSRNOT00060018257	UniProtKB/Swiss-Prot
Gene3D-CATH	NAD(P)-binding Rossmann-like Domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7372031	IMAGE-MGC_LOAD
InterPro	NAD(P)-bd_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SDR_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:305150	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108860	IMAGE-MGC_LOAD
NCBI Gene	305150	ENTREZGENE
PANTHER	17-BETA-HYDROXYSTEROID DEHYDROGENASE 13	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PKSB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	adh_short	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Hsd17b13	PhenoGen
PRINTS	GDHRDH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SDRFAMILY	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000002212	RatGTEx
	ENSRNOG00055026205	RatGTEx
	ENSRNOG00060010776	RatGTEx
Superfamily-SCOP	SSF51735	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5ZU34	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ARG4_RAT	UniProtKB/TrEMBL
	A6K5U1_RAT	UniProtKB/TrEMBL
	A6K5U2_RAT	UniProtKB/TrEMBL
	A6K5U3_RAT	UniProtKB/TrEMBL
	DHB13_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Hsd17b13	hydroxysteroid (17-beta) dehydrogenase 13	MGC108860	short-chain dehydrogenase/reductase 9	Symbol and Name updated	1299863	APPROVED
2005-07-29	MGC108860	short-chain dehydrogenase/reductase 9			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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