Vom1r12 (vomeronasal 1 receptor 12) - Rat Genome Database

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Gene: Vom1r12 (vomeronasal 1 receptor 12) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom1r12 (Ensembl: Vom1r15)
Name: vomeronasal 1 receptor 12 (Ensembl:vomeronasal 1 receptor 15)
RGD ID: 1359512
Description: Predicted to enable pheromone binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway; response to pheromone; and sensory perception of chemical stimulus. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human VN1R3 (vomeronasal 1 receptor 3).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: V1re23; vomernasal 1 receptor Vom1r12; vomeronasal 1 receptor, 12; vomeronasal 1 receptor, E23; vomeronasal type-1 receptor 2; vomeronasal V1r-type receptor V1re23
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8168,863,429 - 68,864,358 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl169,129,178 - 69,130,110 (-)EnsemblGRCr8
mRatBN7.2160,190,443 - 60,191,387 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl160,190,443 - 60,191,363 (-)EnsemblmRatBN7.2
Rnor_6.0160,406,375 - 60,407,295 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl160,406,375 - 60,407,295 (-)Ensemblrn6Rnor6.0
Rnor_5.0161,575,151 - 61,576,071 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4158,063,494 - 58,064,414 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera156,333,503 - 56,334,423 (-)NCBICelera
RGSC_v3.1158,066,438 - 58,067,359 (-)NCBI
Cytogenetic Map1q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
Additional References at PubMed
PMID:19952141  


Genomics

Variants

.
Variants in Vom1r12
5 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat


Expression

RNA-SEQ Expression

endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
respiratory system
1 1 1 1 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000078350   ⟹   ENSRNOP00000072397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl169,129,178 - 69,130,110 (-)Ensembl
mRatBN7.2 Ensembl160,190,443 - 60,191,363 (-)Ensembl
Rnor_6.0 Ensembl160,406,375 - 60,407,295 (-)Ensembl
RefSeq Acc Id: XM_039097045   ⟹   XP_038952973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8168,863,429 - 68,864,358 (-)NCBI
mRatBN7.2160,190,443 - 60,191,387 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038952973 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072397.2
Ensembl Acc Id: ENSRNOP00000072397   ⟸   ENSRNOT00000078350
RefSeq Acc Id: XP_038952973   ⟸   XM_039097045
- UniProtKB: Q5J3E6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5J3E6-F1-model_v2 AlphaFold Q5J3E6 1-306 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359512 AgrOrtholog
BioCyc Gene G2FUF-61210 BioCyc
Ensembl Genes ENSRNOG00000055538 Ensembl
  ENSRNOG00000068768 Ensembl
  ENSRNOG00000083961 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078350.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Vmron_rcpt_1 UniProtKB/TrEMBL
NCBI Gene 494306 ENTREZGENE
PANTHER PTHR24062 UniProtKB/TrEMBL
Pfam V1R UniProtKB/TrEMBL
PhenoGen Vom1r12 PhenoGen
PRINTS VOMERONASL1R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000055538 RatGTEx
  ENSRNOG00000068768 RatGTEx
  ENSRNOG00000083961 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q5J3E6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Vom1r12  vomeronasal 1 receptor 12  Vom1r12  vomeronasal 1 receptor 12  Data merged from RGD:149736379 737654 PROVISIONAL
2021-08-09 Vom1r12  vomeronasal 1 receptor 12      Symbol and Name status set to provisional 45752 PROVISIONAL
2010-06-08 Vom1r12  vomeronasal 1 receptor, 12  V1re23  vomeronasal 1 receptor, E23  Symbol and Name updated 2325755 APPROVED
2008-07-23 V1re23  vomeronasal 1 receptor, E23    vomeronasal V1r-type receptor V1re23  Name updated 1299863 APPROVED
2005-07-29 V1re23  vomeronasal V1r-type receptor V1re23      Symbol and Name status set to provisional 70820 PROVISIONAL