Nub1 (negative regulator of ubiquitin-like proteins 1) - Rat Genome Database

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Gene: Nub1 (negative regulator of ubiquitin-like proteins 1) Rattus norvegicus
Analyze
Symbol: Nub1
Name: negative regulator of ubiquitin-like proteins 1
RGD ID: 1359489
Description: Predicted to be involved in several processes, including positive regulation of proteasomal ubiquitin-dependent protein catabolic process; response to tumor necrosis factor; and response to type II interferon. Predicted to act upstream of or within proteasomal protein catabolic process. Predicted to be located in Lewy body and nucleus. Orthologous to human NUB1 (negative regulator of ubiquitin like proteins 1); PARTICIPATES IN neddylation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BS4; NEDD8 ultimate buster 1; NEDD8 ultimate buster-1; NY-REN-18 antigen; NYREN18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8411,335,376 - 11,366,263 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl411,335,883 - 11,366,462 (-)EnsemblGRCr8
mRatBN7.2410,442,917 - 10,473,689 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl410,442,917 - 10,473,694 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx415,589,502 - 15,619,758 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0411,409,700 - 11,439,956 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.049,761,499 - 9,791,741 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.046,950,870 - 6,981,400 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,951,478 - 6,978,073 (-)Ensemblrn6Rnor6.0
Rnor_5.046,964,480 - 6,994,708 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.445,820,488 - 5,850,809 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera46,058,478 - 6,088,841 (-)NCBICelera
RGSC_v3.145,820,488 - 5,850,809 (-)NCBI
Cytogenetic Map4q11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
Lewy body  (ISO)
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression. Kito K, etal., J Biol Chem 2001 Jun 8;276(23):20603-9. Epub 2001 Mar 19.
3. Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins. Parry G and Estelle M, Semin Cell Dev Biol. 2004 Apr;15(2):221-9.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16707496   PMID:22965877  


Genomics

Comparative Map Data
Nub1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8411,335,376 - 11,366,263 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl411,335,883 - 11,366,462 (-)EnsemblGRCr8
mRatBN7.2410,442,917 - 10,473,689 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl410,442,917 - 10,473,694 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx415,589,502 - 15,619,758 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0411,409,700 - 11,439,956 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.049,761,499 - 9,791,741 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.046,950,870 - 6,981,400 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,951,478 - 6,978,073 (-)Ensemblrn6Rnor6.0
Rnor_5.046,964,480 - 6,994,708 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.445,820,488 - 5,850,809 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera46,058,478 - 6,088,841 (-)NCBICelera
RGSC_v3.145,820,488 - 5,850,809 (-)NCBI
Cytogenetic Map4q11NCBI
NUB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387151,341,812 - 151,378,449 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7151,341,708 - 151,378,461 (+)Ensemblhg38GRCh38
GRCh377151,038,898 - 151,075,535 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,669,791 - 150,706,468 (+)NCBIBuild 36Build 36hg18NCBI36
Celera7145,596,247 - 145,632,781 (+)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7144,850,514 - 144,887,070 (+)NCBIHuRef
CHM1_17151,047,250 - 151,083,821 (+)NCBICHM1_1
T2T-CHM13v2.07152,514,799 - 152,551,295 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27150,368,354 - 150,404,911 (+)NCBI
Nub1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39524,890,813 - 24,915,376 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl524,890,530 - 24,915,376 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38524,685,815 - 24,710,378 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl524,685,532 - 24,710,378 (+)Ensemblmm10GRCm38
MGSCv37524,191,633 - 24,216,373 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36524,196,041 - 24,220,443 (+)NCBIMGSCv36mm8
Celera521,642,444 - 21,667,264 (+)NCBICelera
Cytogenetic Map5A3NCBI
cM Map511.93NCBI
Nub1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,709,791 - 5,739,079 (+)Ensembl
ChiLan1.0NW_0049554915,709,791 - 5,737,620 (+)NCBIChiLan1.0ChiLan1.0
NUB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26187,762,530 - 187,799,621 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1739,772,796 - 39,809,887 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07142,927,730 - 142,964,475 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17155,079,171 - 155,115,913 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7155,079,243 - 155,114,676 (+)EnsemblpanPan2panpan1.1
NUB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11615,355,237 - 15,382,284 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1615,352,476 - 15,381,095 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1615,962,876 - 15,989,492 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01617,077,383 - 17,104,127 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1617,075,097 - 17,104,127 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11615,449,341 - 15,475,957 (+)NCBIUMICH_Zoey_3.1
Nub1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051186,146,984 - 6,177,063 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365276,726,357 - 6,755,318 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365276,726,363 - 6,756,445 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl185,899,568 - 5,928,884 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1185,899,566 - 5,928,981 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,247,107 - 6,274,794 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NUB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121119,525,757 - 119,559,412 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21119,525,932 - 119,560,886 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607215,496,939 - 15,530,260 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nub1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248005,315,381 - 5,345,801 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248005,314,203 - 5,345,301 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Nub1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16153,891,414 - 153,921,488 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nub1
154 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:65
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000045311
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4132668025Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4128392287Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4132668025Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41103870656038706Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4134142783Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4134142783Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)4135396961Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41103870656038706Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4589457557613242Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41103870656038706Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4131106810Rat
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4128392287Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4145429897Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)4135396961Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41103870656038706Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)4135396961Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4132668025Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41103870656038706Rat
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4128392287Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4140471598Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4842855130449094Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4588999950889999Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)4135396961Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4133538816Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)4163900697Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41103870656038706Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4132668025Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41075870140490708Rat

Markers in Region
D4Rat144  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,495,201 - 10,495,445 (+)MAPPERmRatBN7.2
Rnor_6.047,023,217 - 7,023,460NCBIRnor6.0
Rnor_5.047,035,728 - 7,035,971UniSTSRnor5.0
RGSC_v3.445,874,672 - 5,874,916RGDRGSC3.4
RGSC_v3.445,874,673 - 5,874,916UniSTSRGSC3.4
Celera46,111,278 - 6,111,521UniSTS
RGSC_v3.145,874,588 - 5,874,945RGD
SHRSP x BN Map40.0UniSTS
SHRSP x BN Map40.0RGD
Cytogenetic Map4q11UniSTS
D4Got11  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8411,340,159 - 11,340,265 (+)Marker Load Pipeline
mRatBN7.2410,447,700 - 10,447,806 (+)MAPPERmRatBN7.2
Rnor_6.046,955,148 - 6,955,253NCBIRnor6.0
Rnor_5.046,968,758 - 6,968,863UniSTSRnor5.0
RGSC_v3.445,825,098 - 5,825,203UniSTSRGSC3.4
RGSC_v3.445,825,097 - 5,825,203RGDRGSC3.4
RGSC_v3.445,824,765 - 5,824,871RGDRGSC3.4
RGSC_v3.445,824,766 - 5,824,871UniSTSRGSC3.4
RGSC_v3.145,825,098 - 5,825,203RGD
RH 3.4 Map414.0RGD
RH 3.4 Map414.0UniSTS
RH 2.0 Map463.2RGD
Cytogenetic Map4q11UniSTS
RH128463  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,443,019 - 10,443,209 (+)MAPPERmRatBN7.2
Rnor_6.046,950,467 - 6,950,656NCBIRnor6.0
Rnor_5.046,964,077 - 6,964,266UniSTSRnor5.0
RGSC_v3.445,820,085 - 5,820,274UniSTSRGSC3.4
Celera46,058,075 - 6,058,264UniSTS
Cytogenetic Map4q11UniSTS
RH128761  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,443,580 - 10,443,766 (+)MAPPERmRatBN7.2
Rnor_6.046,951,028 - 6,951,213NCBIRnor6.0
Rnor_5.046,964,638 - 6,964,823UniSTSRnor5.0
RGSC_v3.445,820,646 - 5,820,831UniSTSRGSC3.4
Celera46,058,636 - 6,058,821UniSTS
Cytogenetic Map4q11UniSTS
RH138616  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,448,936 - 10,449,117 (+)MAPPERmRatBN7.2
Rnor_6.046,956,381 - 6,956,561NCBIRnor6.0
Rnor_5.046,969,991 - 6,970,171UniSTSRnor5.0
RGSC_v3.445,826,331 - 5,826,511UniSTSRGSC3.4
Celera46,064,102 - 6,064,282UniSTS
Cytogenetic Map4q11UniSTS
RH139609  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,443,184 - 10,443,376 (+)MAPPERmRatBN7.2
Rnor_6.046,950,632 - 6,950,823NCBIRnor6.0
Rnor_5.046,964,242 - 6,964,433UniSTSRnor5.0
RGSC_v3.445,820,250 - 5,820,441UniSTSRGSC3.4
Celera46,058,240 - 6,058,431UniSTS
Cytogenetic Map4q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000045311   ⟹   ENSRNOP00000048314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl411,336,490 - 11,366,146 (-)Ensembl
mRatBN7.2 Ensembl410,444,031 - 10,473,694 (-)Ensembl
Rnor_6.0 Ensembl46,951,478 - 6,978,073 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098051   ⟹   ENSRNOP00000086699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl411,335,883 - 11,365,856 (-)Ensembl
mRatBN7.2 Ensembl410,442,917 - 10,471,056 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108045   ⟹   ENSRNOP00000078815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl411,335,883 - 11,366,146 (-)Ensembl
mRatBN7.2 Ensembl410,442,919 - 10,470,461 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115102   ⟹   ENSRNOP00000076727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl411,335,883 - 11,366,462 (-)Ensembl
mRatBN7.2 Ensembl410,442,917 - 10,472,315 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000161628   ⟹   ENSRNOP00000107436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl411,335,883 - 11,366,067 (-)Ensembl
RefSeq Acc Id: NM_001013925   ⟹   NP_001013947
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8411,335,882 - 11,366,146 (-)NCBI
mRatBN7.2410,443,423 - 10,473,689 (-)NCBI
Rnor_6.046,950,870 - 6,981,400 (-)NCBI
Rnor_5.046,964,480 - 6,994,708 (-)NCBI
RGSC_v3.445,820,488 - 5,850,809 (-)RGD
Celera46,058,478 - 6,088,841 (-)RGD
Sequence:
RefSeq Acc Id: XM_039107214   ⟹   XP_038963142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8411,335,376 - 11,366,263 (-)NCBI
mRatBN7.2410,442,917 - 10,473,681 (-)NCBI
RefSeq Acc Id: XM_039107215   ⟹   XP_038963143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8411,335,376 - 11,355,597 (-)NCBI
mRatBN7.2410,442,917 - 10,463,139 (-)NCBI
RefSeq Acc Id: XM_063285691   ⟹   XP_063141761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8411,335,376 - 11,366,065 (-)NCBI
RefSeq Acc Id: NP_001013947   ⟸   NM_001013925
- UniProtKB: Q5XIT4 (UniProtKB/TrEMBL),   A0A8I6A4A9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048314   ⟸   ENSRNOT00000045311
RefSeq Acc Id: XP_038963142   ⟸   XM_039107214
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038963143   ⟸   XM_039107215
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000078815   ⟸   ENSRNOT00000108045
Ensembl Acc Id: ENSRNOP00000086699   ⟸   ENSRNOT00000098051
Ensembl Acc Id: ENSRNOP00000076727   ⟸   ENSRNOT00000115102
RefSeq Acc Id: XP_063141761   ⟸   XM_063285691
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A4A9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000107436   ⟸   ENSRNOT00000161628
Protein Domains
NEDD8 ultimate buster 1 ubiquitin-like   UBA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F7ES73-F1-model_v2 AlphaFold F7ES73 1-612 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359489 AgrOrtholog
BioCyc Gene G2FUF-46056 BioCyc
Ensembl Genes ENSRNOG00000009282 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045311.6 UniProtKB/TrEMBL
  ENSRNOT00000098051.2 UniProtKB/TrEMBL
  ENSRNOT00000108045 ENTREZGENE
  ENSRNOT00000108045.2 UniProtKB/TrEMBL
  ENSRNOT00000115102.2 UniProtKB/TrEMBL
  ENSRNOT00000161628 ENTREZGENE
  ENSRNOT00000161628.1 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131376 IMAGE-MGC_LOAD
InterPro NUB1 UniProtKB/TrEMBL
  NUB1_ubiquitin-like_dom UniProtKB/TrEMBL
  TPR-like_helical_dom UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
  UBA/transl_elong_EF1B_N_euk UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
KEGG Report rno:296731 UniProtKB/TrEMBL
MGC_CLONE MGC:94244 IMAGE-MGC_LOAD
NCBI Gene 296731 ENTREZGENE
PANTHER NEDD8 ULTIMATE BUSTER 1 UniProtKB/TrEMBL
  PTHR12948 UniProtKB/TrEMBL
Pfam UBA UniProtKB/TrEMBL
  Ubiquitin_5 UniProtKB/TrEMBL
PhenoGen Nub1 PhenoGen
PROSITE UBA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009282 RatGTEx
SMART UBA UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  UBA_like UniProtKB/TrEMBL
UniProt A0A8I5Y4X4_RAT UniProtKB/TrEMBL
  A0A8I5ZLQ1_RAT UniProtKB/TrEMBL
  A0A8I6A4A9 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LZ87_RAT UniProtKB/TrEMBL
  A6K528_RAT UniProtKB/TrEMBL
  A6K529_RAT UniProtKB/TrEMBL
  A6K530_RAT UniProtKB/TrEMBL
  F7ES73_RAT UniProtKB/TrEMBL
  Q5XIT4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Nub1  negative regulator of ubiquitin-like proteins 1  Nub1  NEDD8 ultimate buster-1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 Nub1  NEDD8 ultimate buster-1      Symbol and Name status set to provisional 70820 PROVISIONAL