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Gene: Mocs2 (molybdenum cofactor synthesis 2) Rattus norvegicus

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Symbol:

Mocs2

Name:

molybdenum cofactor synthesis 2

RGD ID:

1359477

Description:

Predicted to enable identical protein binding activity. Predicted to contribute to molybdopterin synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of molybdopterin synthase complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type B. Orthologous to human MOCS2 (molybdenum cofactor synthesis 2); PARTICIPATES IN molybdenum cofactor biosynthetic pathway; folate metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

MGC94220; MOCS2B; molybdenum cofactor synthesis protein 2 large subunit; molybdenum cofactor synthesis protein 2B; molybdopterin synthase; molybdopterin synthase catalytic subunit; molybdopterin synthase sulfur carrier subunit

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MOCS2 (molybdenum cofactor synthesis 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Mocs2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mocs2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MOCS2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MOCS2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mocs2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MOCS2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MOCS2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mocs2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Mocs2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MOCS2 (molybdenum cofactor synthesis 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mocs2 (molybdenum cofactor synthesis 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nmrk-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	nmrk-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Mocs2B	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mocs2	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	LOC105945135	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	48,237,655 - 48,249,394 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	48,237,655 - 48,249,394 (+)	Ensembl				GRCr8
mRatBN7.2	2	46,504,588 - 46,516,327 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	46,504,588 - 46,516,324 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	53,614,202 - 53,625,948 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	51,672,578 - 51,684,324 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	46,540,417 - 46,552,139 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	46,980,964 - 46,992,886 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	46,980,976 - 46,992,883 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	71,520,174 - 71,532,084 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	46,948,321 - 46,960,060 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	42,260,839 - 42,272,490 (+)	NCBI		Celera
RGSC_v3.1	2	46,876,587 - 46,888,290 (+)	NCBI
Cytogenetic Map	2	q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

inherited metabolic disorder (ISO)

molybdenum cofactor deficiency (ISO)

molybdenum cofactor deficiency type A (ISO)

molybdenum cofactor deficiency type B (ISO,ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1,1-trichloroethane (ISO)

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

azoxystrobin (EXP)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

chlordecone (ISO)

chlorpyrifos (EXP)

cisplatin (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP)

diquat (ISO)

doxorubicin (ISO)

flutamide (EXP)

folic acid (ISO)

glyphosate (EXP)

hydrogen peroxide (ISO)

imidacloprid (EXP)

methylmercury chloride (ISO)

Muraglitazar (EXP)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

nefazodone (EXP)

nimesulide (EXP)

paracetamol (ISO)

perfluorooctanoic acid (EXP)

quercetin (ISO)

rotenone (EXP)

silicon dioxide (ISO)

sodium arsenite (ISO)

Tesaglitazar (EXP)

tetrachloromethane (EXP)

thiabendazole (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (EXP,ISO)

triptonide (ISO)

troglitazone (EXP)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

Mo-molybdopterin cofactor biosynthetic process (IEA,ISO,ISS)

molybdopterin cofactor biosynthetic process (IEA,ISO)

Cellular Component

cytosol (IBA,IEA,ISO,ISS)

molybdopterin synthase complex (IEA,ISO,ISS)

nucleus (IEA)

Molecular Function

identical protein binding (ISO)

molybdopterin synthase activity (IEA,ISO,ISS)

protein binding (ISO)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

folate metabolic pathway (IEA)

molybdenum cofactor biosynthetic pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Cell biology of molybdenum.	Mendel RR and Bittner F, Biochim Biophys Acta. 2006 Jul;1763(7):621-35. Epub 2006 May 12.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	Mutations in the molybdenum cofactor biosynthetic genes MOCS1, MOCS2, and GEPH.	Reiss J and Johnson JL, Hum Mutat 2003 Jun;21(6):569-76.
8.	Human molybdopterin synthase gene: genomic structure and mutations in molybdenum cofactor deficiency type B.	Reiss J, etal., Am J Hum Genet 1999 Mar;64(3):706-11.
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Comprehensive gene review and curation	RGD comprehensive gene curation
13.	The two subunits of human molybdopterin synthase: evidence for a bicistronic messenger RNA with overlapping reading frames.	Sloan J, etal., Nucleic Acids Res 1999 Feb 1;27(3):854-8.
14.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11591653	PMID:12732628	PMID:15073332	PMID:23376485

Genomics

Comparative Map Data

Mocs2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	48,237,655 - 48,249,394 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	48,237,655 - 48,249,394 (+)	Ensembl				GRCr8
mRatBN7.2	2	46,504,588 - 46,516,327 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	46,504,588 - 46,516,324 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	53,614,202 - 53,625,948 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	51,672,578 - 51,684,324 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	46,540,417 - 46,552,139 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	46,980,964 - 46,992,886 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	46,980,976 - 46,992,883 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	71,520,174 - 71,532,084 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	46,948,321 - 46,960,060 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	42,260,839 - 42,272,490 (+)	NCBI		Celera
RGSC_v3.1	2	46,876,587 - 46,888,290 (+)	NCBI
Cytogenetic Map	2	q14	NCBI

MOCS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	53,095,679 - 53,109,757 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	53,095,679 - 53,113,016 (-)	Ensembl			hg38	GRCh38
GRCh37	5	52,391,509 - 52,405,587 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	52,429,649 - 52,441,355 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	52,429,653 - 52,441,355	NCBI
Celera	5	49,347,470 - 49,359,176 (-)	NCBI		Celera
Cytogenetic Map	5	q11.2	NCBI
HuRef	5	49,363,558 - 49,377,653 (-)	NCBI		HuRef
CHM1_1	5	52,394,058 - 52,408,152 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	53,923,465 - 53,937,543 (-)	NCBI		T2T-CHM13v2.0

Mocs2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	114,954,707 - 114,965,960 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	114,954,772 - 114,968,811 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	114,818,160 - 114,829,420 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	114,818,236 - 114,832,275 (+)	Ensembl			mm10	GRCm38
MGSCv37	13	115,608,445 - 115,619,628 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	115,939,164 - 115,949,607 (+)	NCBI		MGSCv36	mm8
Celera	13	119,161,937 - 119,173,119 (+)	NCBI		Celera
Cytogenetic Map	13	D2.2	NCBI
cM Map	13	64.61	NCBI

Mocs2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955446	14,295,737 - 14,307,838 (+)	Ensembl
ChiLan1.0 Ensembl	NW_004955446	14,295,707 - 14,298,228 (+)	Ensembl
ChiLan1.0	NW_004955446	14,295,737 - 14,305,735 (+)	NCBI	ChiLan1.0	ChiLan1.0

MOCS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	60,831,376 - 60,843,005 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	58,984,997 - 58,996,220 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	60,920,268 - 60,931,990 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	62,539,208 - 62,550,926 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	62,539,214 - 62,550,921 (+)	Ensembl			panPan2	panpan1.1

MOCS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	62,153,828 - 62,164,154 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	62,153,296 - 62,185,492 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	61,928,792 - 61,939,117 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	62,651,866 - 62,662,174 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	62,652,443 - 62,665,845 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	62,427,116 - 62,437,429 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	62,551,658 - 62,561,990 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	63,078,354 - 63,088,687 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mocs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	205,369,033 - 205,380,226 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936480	14,307,791 - 14,312,812 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0 Ensembl	NW_004936480	14,302,798 - 14,314,086 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936480	14,302,824 - 14,313,265 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MOCS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	32,436,205 - 32,462,521 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	16	32,427,783 - 32,462,362 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	34,270,548 - 34,290,713 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MOCS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	49,387,923 - 49,399,902 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	49,386,487 - 49,399,928 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666082	1,727,742 - 1,739,745 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mocs2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624759	6,261,933 - 6,271,509 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624759	6,261,970 - 6,272,246 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mocs2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	181,888,287 - 181,900,225 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Mocs2
84 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	165
Count of miRNA genes:	126
Interacting mature miRNAs:	138
Transcripts:	ENSRNOT00000015781
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	13325041	58325041	Rat
7387318	Stl32	Serum triglyceride level QTL 32	3.2	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	24117813	69117813	Rat
10755436	Coatc8	Coat color QTL 8		0.02431	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	36750344	81750344	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
9590080	Insglur4	Insulin/glucose ratio QTL 4	28.7	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	2	6152767	51152767	Rat
1300160	Hrtrt3	Heart rate QTL 3	3.62		heart pumping trait (VT:2000009)	absolute change in heart rate (CMO:0000534)	2	35614083	53462005	Rat
1579916	Bp270	Blood pressure QTL 270		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	16051883	61051883	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	22038044	67038044	Rat
731166	Mamtr2	Mammary tumor resistance QTL 2		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	9623581	54623581	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
152025242	Bw191	Body weight QTL 191	3.62		body mass (VT:0001259)		2	40306867	124537199	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	27148328	145807373	Rat
9685065	Swd6	Spike wave discharge measurement QTL 6	5.8	0.01	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge rate (CMO:0001739)	2	40957423	50526673	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	28889991	73889991	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	41801363	104744824	Rat
1331764	Bp205	Blood pressure QTL 205	3.476		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	14368707	59368707	Rat
631208	Bw1	Body weight QTL1	5.09		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	2	44904355	85286097	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	159440891	Rat
1300155	Bp174	Blood pressure QTL 174	4.09		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	44537979	112567334	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	7605533	104774005	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	83465677	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	184731399	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	5736325	50736325	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
2306903	Bp336	Blood pressure QTL 336		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	38426449	111295694	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	28652666	139067443	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	18227137	63227137	Rat
61371	Edpm1	Estrogen-dependent pituitary mass QTL 1	4	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	36868643	81868643	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	44904355	89904355	Rat
1582246	Cm60	Cardiac mass QTL 60	5.8		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	33269996	78269996	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	73652666	Rat

Markers in Region

D5Wox6

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	46,509,113 - 46,509,732 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	46,985,503 - 46,986,121	NCBI	Rnor6.0
Rnor_5.0	2	71,524,701 - 71,525,319	UniSTS	Rnor5.0
RGSC_v3.4	2	46,952,847 - 46,953,465	UniSTS	RGSC3.4
Celera	2	42,265,277 - 42,265,895	UniSTS
Cytogenetic Map	2	q14	UniSTS

RH133558

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	46,515,655 - 46,515,860 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	46,992,215 - 46,992,419	NCBI	Rnor6.0
Rnor_5.0	2	71,531,413 - 71,531,617	UniSTS	Rnor5.0
RGSC_v3.4	2	46,959,389 - 46,959,593	UniSTS	RGSC3.4
Celera	2	42,271,819 - 42,272,023	UniSTS
RH 3.4 Map	2	304.4	UniSTS
Cytogenetic Map	2	q14	UniSTS

BF404043

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	46,508,124 - 46,508,318 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	46,984,514 - 46,984,707	NCBI	Rnor6.0
Rnor_5.0	2	71,523,712 - 71,523,905	UniSTS	Rnor5.0
RGSC_v3.4	2	46,951,858 - 46,952,051	UniSTS	RGSC3.4
Celera	2	42,264,288 - 42,264,481	UniSTS
RH 3.4 Map	2	292.3	UniSTS
Cytogenetic Map	2	q14	UniSTS

AW535104

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	46,508,195 - 46,508,347 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	46,984,585 - 46,984,736	NCBI	Rnor6.0
Rnor_5.0	2	71,523,783 - 71,523,934	UniSTS	Rnor5.0
RGSC_v3.4	2	46,951,929 - 46,952,080	UniSTS	RGSC3.4
Celera	2	42,264,359 - 42,264,510	UniSTS
RH 3.4 Map	2	294.8	UniSTS
Cytogenetic Map	2	q14	UniSTS

RH139819

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	46,516,084 - 46,516,277 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	46,992,644 - 46,992,836	NCBI	Rnor6.0
Rnor_5.0	2	71,531,842 - 71,532,034	UniSTS	Rnor5.0
RGSC_v3.4	2	46,959,818 - 46,960,010	UniSTS	RGSC3.4
Celera	2	42,272,248 - 42,272,440	UniSTS
Cytogenetic Map	2	q14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001007633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001162413	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001395667	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001395668	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001395669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590715	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO554692	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM123325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000082990 ⟹ ENSRNOP00000073722

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	48,237,655 - 48,249,391 (+)	Ensembl
mRatBN7.2 Ensembl	2	46,504,588 - 46,516,324 (+)	Ensembl
Rnor_6.0 Ensembl	2	46,981,010 - 46,992,883 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083668 ⟹ ENSRNOP00000069073

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	46,980,976 - 46,992,883 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000151323 ⟹ ENSRNOP00000100945

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	48,238,812 - 48,249,394 (+)	Ensembl

RefSeq Acc Id:

NM_001007633 ⟹ NP_001007634

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	48,237,655 - 48,249,394 (+)	NCBI
mRatBN7.2	2	46,504,588 - 46,516,327 (+)	NCBI
Rnor_6.0	2	46,980,976 - 46,992,886 (+)	NCBI
Rnor_5.0	2	71,520,174 - 71,532,084 (+)	NCBI
RGSC_v3.4	2	46,948,321 - 46,960,060 (+)	RGD
Celera	2	42,260,839 - 42,272,490 (+)	RGD

Sequence:

show sequence

GTGGAGCATCCGGCTGCGCATGCGCCCTGAGTCACCGGCTCCGACGGGGTTGGTGAACTGGCTC
CCGGCAGTGTAGCGGGATGGTTCCTAGGTGTCAGGTTGGCTGATGTTAGAAACCAGGTGATATT
TGCTGTTCGTCAAGAGTATGTCGAGCTTGGAGATCAACAACTCCTGCTTCAGCCTGGAGACGAA
GTTGCCATCATCCCACCAATCAGTGGAGGATAGTGCGTCTGAGCCATCGGGGTATGAGGCGAAG
GACCCTCCACAGGATACCTTGAAAGATGTGGATGATGTGCTGGAGAAACCTAAGGACATAATAC
AGTTCACTGCCAAGAAGCTCTCAGTGGGGGAAGTGTCACAGCTGGTGGTGTCCCCTCTGTGTGG
CGCAGTGTCTCTCTTTGTAGGGACTACAAGAAATAACTTCGAAGGCAAGAAAGTCATTAGCTTA
GAATATGAAGCATATCTACCCATGGCAGAAAATGAAATCAGAAAAATTTGCAATGACATTCGAC
AGAAATGGCCAGTGAGGCACATAGCGGTGTTCCATCGGCTTGGTCTGGTTCCAGTGTCAGAAGC
AAGCACAGTTATTGCTGTGTCCTCAGCTCACAGAGCCGCGTCCCTTGAAGCCGTGAGCTACGCC
ATTGATTCTTTAAAAGCCAAGGTGCCCATATGGAAGAAGGAAATATATGAAGAATCAACATCAT
CTTGGAAAAGAAACAAGGAATGCTTCTGGGCAGCTGATGACTAGTCAAGTTTTGGTGCACTGAA
TCTTAAATTTGGTAAATAATCGCTTAGGTTACACCAATGGAGAGCTAGGGAAGTGCCCAAGTGT
GTGGGATGAGGAGCTGCGTAGGACCTAAAGCTGGGAAGACATGGCTTAACTTGAACCTTCTGTG
ACTAACTCCTAGTCGTAGCCAGCTCACAACGAGCTGCAGCCTTCCTTTCACCATCAGCTGTCCC
AGGAAGACCTACTGTCCCACAGGGTATTGACGCATCGTGATAAGACATGTGTTACAAAAAATTG
ACGGAATCAGAAAATCATTCTCAGTTGTGACATTACATATTTTACATAACTTAGAAGTGAACCT
AAATAAATCATGATTTAAATTAAAAATAGATTCTGTTTCTCTTTTAGTCAGTGATAATACCTAA
GGGGTTTTACATTACAGACACCTCTCTGACTTCAGAATCCATAATTACACACAGTAAGGCTTTT
TTTATATCTCATTGGTTGTCAATATTCTCATCACTGTACAGATTAGCATAAAACTGTTCTAAAA
CTAACCAGCAGCAAGGTGGTTTATGTTAAAATGATGTATGATGCTTAAAAGTTGGCCCACAACT
ATTTGAGGACACTGTGTAATTATTTACTAAAGTAGTTTGGATAGTTTTCATAATGTTTATGTAA
CACTGGCCTGTGTGAAATTATTACTAAACAAATTAAATTTTCTGCAAGATTTTTATACCAAAAA
AAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001162413 ⟹ NP_001155885

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	48,237,655 - 48,249,394 (+)	NCBI
mRatBN7.2	2	46,504,588 - 46,516,327 (+)	NCBI
Rnor_6.0	2	46,980,976 - 46,992,886 (+)	NCBI
Rnor_5.0	2	71,520,174 - 71,532,084 (+)	NCBI
RGSC_v3.4	2	46,948,321 - 46,960,060 (+)	RGD
Celera	2	42,260,839 - 42,272,490 (+)	RGD

Sequence:

show sequence

GTGGAGCATCCGGCTGCGCATGCGCCCTGAGTCACCGGCTCCGACGGGGTTGGTGAACTGGCTC
CCGGCAGTGTAGCGGGATGGTTCCTAGGTGTCAGATCGAAGTGTTGTATTTTGCAAAAAGTGCT
GAAATCGCTGGCGTTCGCTCCGAGACCATCTCTGTGCCACAGGAAATCAAGGCATCACAGCTGT
GGCAGGAGCTAGAGACTCTCCATCCTGGGTTGGCTGATGTTAGAAACCAGGTGATATTTGCTGT
TCGTCAAGAGTATGTCGAGCTTGGAGATCAACAACTCCTGCTTCAGCCTGGAGACGAAGTTGCC
ATCATCCCACCAATCAGTGGAGGATAGTGCGTCTGAGCCATCGGGGTATGAGGCGAAGGACCCT
CCACAGGATACCTTGAAAGATGTGGATGATGTGCTGGAGAAACCTAAGGACATAATACAGTTCA
CTGCCAAGAAGCTCTCAGTGGGGGAAGTGTCACAGCTGGTGGTGTCCCCTCTGTGTGGCGCAGT
GTCTCTCTTTGTAGGGACTACAAGAAATAACTTCGAAGGCAAGAAAGTCATTAGCTTAGAATAT
GAAGCATATCTACCCATGGCAGAAAATGAAATCAGAAAAATTTGCAATGACATTCGACAGAAAT
GGCCAGTGAGGCACATAGCGGTGTTCCATCGGCTTGGTCTGGTTCCAGTGTCAGAAGCAAGCAC
AGTTATTGCTGTGTCCTCAGCTCACAGAGCCGCGTCCCTTGAAGCCGTGAGCTACGCCATTGAT
TCTTTAAAAGCCAAGGTGCCCATATGGAAGAAGGAAATATATGAAGAATCAACATCATCTTGGA
AAAGAAACAAGGAATGCTTCTGGGCAGCTGATGACTAGTCAAGTTTTGGTGCACTGAATCTTAA
ATTTGGTAAATAATCGCTTAGGTTACACCAATGGAGAGCTAGGGAAGTGCCCAAGTGTGTGGGA
TGAGGAGCTGCGTAGGACCTAAAGCTGGGAAGACATGGCTTAACTTGAACCTTCTGTGACTAAC
TCCTAGTCGTAGCCAGCTCACAACGAGCTGCAGCCTTCCTTTCACCATCAGCTGTCCCAGGAAG
ACCTACTGTCCCACAGGGTATTGACGCATCGTGATAAGACATGTGTTACAAAAAATTGACGGAA
TCAGAAAATCATTCTCAGTTGTGACATTACATATTTTACATAACTTAGAAGTGAACCTAAATAA
ATCATGATTTAAATTAAAAATAGATTCTGTTTCTCTTTTAGTCAGTGATAATACCTAAGGGGTT
TTACATTACAGACACCTCTCTGACTTCAGAATCCATAATTACACACAGTAAGGCTTTTTTTATA
TCTCATTGGTTGTCAATATTCTCATCACTGTACAGATTAGCATAAAACTGTTCTAAAACTAACC
AGCAGCAAGGTGGTTTATGTTAAAATGATGTATGATGCTTAAAAGTTGGCCCACAACTATTTGA
GGACACTGTGTAATTATTTACTAAAGTAGTTTGGATAGTTTTCATAATGTTTATGTAACACTGG
CCTGTGTGAAATTATTACTAAACAAATTAAATTTTCTGCAAGATTTTTATACCAAAAAAAAAAA
AAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001395667 ⟹ NP_001382596

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	48,237,655 - 48,249,394 (+)	NCBI
mRatBN7.2	2	46,504,588 - 46,516,327 (+)	NCBI

RefSeq Acc Id:

NM_001395668 ⟹ NP_001382597

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	48,237,655 - 48,249,394 (+)	NCBI
mRatBN7.2	2	46,504,588 - 46,516,327 (+)	NCBI

RefSeq Acc Id:

NM_001395669 ⟹ NP_001382598

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	48,237,655 - 48,249,394 (+)	NCBI
mRatBN7.2	2	46,504,588 - 46,516,327 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001007634	(Get FASTA)	NCBI Sequence Viewer
	NP_001155885	(Get FASTA)	NCBI Sequence Viewer
	NP_001382596	(Get FASTA)	NCBI Sequence Viewer
	NP_001382597	(Get FASTA)	NCBI Sequence Viewer
	NP_001382598	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79181	(Get FASTA)	NCBI Sequence Viewer
	EDM10385	(Get FASTA)	NCBI Sequence Viewer
	EDM10386	(Get FASTA)	NCBI Sequence Viewer
	EDM10387	(Get FASTA)	NCBI Sequence Viewer
	EDM10388	(Get FASTA)	NCBI Sequence Viewer
	EDM10389	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000073722
	ENSRNOP00000073722.1
GenBank Protein	Q6AY59	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001007634 ⟸ NM_001007633
- Peptide Label:	isoform Mocs2B-1
- UniProtKB:	Q6AY59 (UniProtKB/Swiss-Prot), A6I5T0 (UniProtKB/TrEMBL), A6I5S7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSLEINNSCFSLETKLPSSHQSVEDSASEPSGYEAKDPPQDTLKDVDDVLEKPKDIIQFTAKK LSVGEVSQLVVSPLCGAVSLFVGTTRNNFEGKKVISLEYEAYLPMAENEIRKICNDIRQKWPVR HIAVFHRLGLVPVSEASTVIAVSSAHRAASLEAVSYAIDSLKAKVPIWKKEIYEESTSSWKRNK ECFWAADD hide sequence

RefSeq Acc Id:	NP_001155885 ⟸ NM_001162413
- Peptide Label:	isoform Mocs2A
- UniProtKB:	Q6AY59 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MVPRCQIEVLYFAKSAEIAGVRSETISVPQEIKASQLWQELETLHPGLADVRNQVIFAVRQEYV ELGDQQLLLQPGDEVAIIPPISGG hide sequence

Ensembl Acc Id:

ENSRNOP00000073722 ⟸ ENSRNOT00000082990

Ensembl Acc Id:

ENSRNOP00000069073 ⟸ ENSRNOT00000083668

RefSeq Acc Id:	NP_001382597 ⟸ NM_001395668
- Peptide Label:	isoform Mocs2A

RefSeq Acc Id:	NP_001382598 ⟸ NM_001395669
- Peptide Label:	isoform Mocs2A

RefSeq Acc Id:	NP_001382596 ⟸ NM_001395667
- Peptide Label:	isoform Mocs2B-2
- UniProtKB:	A6I5T1 (UniProtKB/TrEMBL), A6I5S8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000100945 ⟸ ENSRNOT00000151323

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AY59-F1-model_v2	AlphaFold	Q6AY59	1-200	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691147

Promoter ID:

EPDNEW_R1672

Type:

initiation region

Name:

Mocs2_1

Description:

molybdenum cofactor synthesis 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	46,981,009 - 46,981,069	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359477	AgrOrtholog
BioCyc Gene	G2FUF-54327	BioCyc
BioCyc Pathway	PWY-6823 [molybdopterin biosynthesis]	BioCyc
BioCyc Pathway Image	PWY-6823	BioCyc
Ensembl Genes	ENSRNOG00000056325	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000082990	ENTREZGENE
	ENSRNOT00000082990.2	UniProtKB/Swiss-Prot
Gene3D-CATH	3.90.1170.40	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7130858	IMAGE-MGC_LOAD
InterPro	MoaE_sf	UniProtKB/Swiss-Prot
	MOCS2B_euk	UniProtKB/Swiss-Prot
	Mopterin_biosynth_MoaE	UniProtKB/Swiss-Prot
KEGG Report	rno:294753	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94220	IMAGE-MGC_LOAD
NCBI Gene	294753	ENTREZGENE
PANTHER	MOLYBDOPTERIN SYNTHASE RELATED	UniProtKB/Swiss-Prot
Pfam	MoaE	UniProtKB/Swiss-Prot
PhenoGen	Mocs2	PhenoGen
RatGTEx	ENSRNOG00000056325	RatGTEx
Superfamily-SCOP	SSF54690	UniProtKB/Swiss-Prot
UniProt	A0ABK0KZY8_RAT	UniProtKB/TrEMBL
	A6I5S7	ENTREZGENE, UniProtKB/TrEMBL
	A6I5S8	ENTREZGENE, UniProtKB/TrEMBL
	A6I5S9_RAT	UniProtKB/TrEMBL
	A6I5T0	ENTREZGENE, UniProtKB/TrEMBL
	A6I5T1	ENTREZGENE, UniProtKB/TrEMBL
	MOC2B_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Mocs2	molybdenum cofactor synthesis 2		molybdopterin synthase	Name updated	1299863	APPROVED
2005-07-29	Mocs2	molybdopterin synthase			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

BioCyc Pathways