Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Zcchc12 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Zcchc12 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of ZCCHC12 mRNA | CTD | PMID:22206623 | Zcchc12 | Rat | 1,3-dinitrobenzene | increases expression | EXP | | 6480464 | 3-dinitrobenzene results in increased expression of ZCCHC12 mRNA | CTD | PMID:21983209 | Zcchc12 | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of ZCCHC12 mRNA | CTD | PMID:32145629 | Zcchc12 | Rat | 17beta-estradiol 3-benzoate | decreases expression | EXP | | 6480464 | estradiol 3-benzoate results in decreased expression of ZCCHC12 mRNA | CTD | PMID:32741896 | Zcchc12 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Zcchc12 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZCCHC12 mRNA | CTD | PMID:21570461 | Zcchc12 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ZCCHC12 mRNA | CTD | PMID:33387578 | Zcchc12 | Rat | 2-methylcholine | affects expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of ZCCHC12 mRNA | CTD | PMID:21179406 | Zcchc12 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZCCHC12 mRNA | CTD | PMID:23196670 | Zcchc12 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Decitabine affects the expression of ZCCHC12 mRNA | CTD | PMID:23300844 | Zcchc12 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ZCCHC12 mRNA | CTD | PMID:24780913|PMID:25825206 | Zcchc12 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of ZCCHC12 mRNA | CTD | PMID:31881176 | Zcchc12 | Rat | acrylamide | decreases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of ZCCHC12 mRNA | CTD | PMID:32763439 | Zcchc12 | Rat | all-trans-retinoic acid | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ZCCHC12 mRNA | CTD | PMID:21934132 | Zcchc12 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of ZCCHC12 mRNA | CTD | PMID:38685447 | Zcchc12 | Rat | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of ZCCHC12 mRNA | CTD | PMID:30779732 | Zcchc12 | Rat | antirheumatic drug | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of ZCCHC12 mRNA | CTD | PMID:24449571 | Zcchc12 | Rat | benzo[a]pyrene | decreases expression | ISO | Zcchc12 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ZCCHC12 mRNA | CTD | PMID:27195522 | Zcchc12 | Rat | benzo[a]pyrene | increases methylation | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ZCCHC12 exon | CTD | PMID:27901495 | Zcchc12 | Rat | benzo[a]pyrene | affects methylation | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ZCCHC12 promoter | CTD | PMID:27901495 | Zcchc12 | Rat | benzo[a]pyrene | decreases methylation | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of ZCCHC12 5' UTR | CTD | PMID:27901495 | Zcchc12 | Rat | beta-lapachone | decreases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of ZCCHC12 mRNA | CTD | PMID:38218311 | Zcchc12 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Zcchc12 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Zcchc12 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of ZCCHC12 mRNA | CTD | PMID:34319233 | Zcchc12 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ZCCHC12 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:34947998 | Zcchc12 | Rat | bisphenol A | decreases expression | ISO | Zcchc12 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ZCCHC12 mRNA | CTD | PMID:32156529 | Zcchc12 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ZCCHC12 mRNA | CTD | PMID:32145629 | Zcchc12 | Rat | Butylbenzyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Zcchc12 | Rat | CGP 52608 | multiple interactions | ISO | ZCCHC12 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ZCCHC12 gene] | CTD | PMID:28238834 | Zcchc12 | Rat | chlordecone | increases expression | ISO | Zcchc12 (Mus musculus) | 6480464 | Chlordecone results in increased expression of ZCCHC12 mRNA | CTD | PMID:33711761 | Zcchc12 | Rat | cisplatin | affects expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Cisplatin affects the expression of ZCCHC12 mRNA | CTD | PMID:23300844 | Zcchc12 | Rat | copper atom | multiple interactions | ISO | ZCCHC12 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of ZCCHC12 mRNA | CTD | PMID:20971185 | Zcchc12 | Rat | copper(0) | multiple interactions | ISO | ZCCHC12 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of ZCCHC12 mRNA | CTD | PMID:20971185 | Zcchc12 | Rat | copper(II) sulfate | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ZCCHC12 mRNA | CTD | PMID:19549813 | Zcchc12 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of ZCCHC12 mRNA | CTD | PMID:26577399 | Zcchc12 | Rat | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Zcchc12 | Rat | diethyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Zcchc12 | Rat | diisobutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Zcchc12 | Rat | diisononyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... | CTD | PMID:31199487 | Zcchc12 | Rat | doxorubicin | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of ZCCHC12 mRNA | CTD | PMID:30031762 | Zcchc12 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of ZCCHC12 mRNA | CTD | PMID:29391264 | Zcchc12 | Rat | ethanol | decreases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Ethanol results in decreased expression of ZCCHC12 mRNA | CTD | PMID:23378141 | Zcchc12 | Rat | ethanol | increases expression | ISO | Zcchc12 (Mus musculus) | 6480464 | Ethanol results in increased expression of ZCCHC12 mRNA | CTD | PMID:30319688 | Zcchc12 | Rat | ethanol | multiple interactions | ISO | ZCCHC12 (Homo sapiens) | 6480464 | [Ethanol co-treated with Folic Acid] results in decreased expression of ZCCHC12 mRNA | CTD | PMID:23378141 | Zcchc12 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of ZCCHC12 mRNA | CTD | PMID:30307764 | Zcchc12 | Rat | folic acid | multiple interactions | ISO | ZCCHC12 (Homo sapiens) | 6480464 | [Ethanol co-treated with Folic Acid] results in decreased expression of ZCCHC12 mRNA | CTD | PMID:23378141 | Zcchc12 | Rat | genistein | increases expression | ISO | Zcchc12 (Mus musculus) | 6480464 | Genistein results in increased expression of ZCCHC12 mRNA | CTD | PMID:32186404 | Zcchc12 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of ZCCHC12 mRNA | CTD | PMID:33387578 | Zcchc12 | Rat | irinotecan | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Irinotecan analog results in increased expression of ZCCHC12 mRNA | CTD | PMID:18927307 | Zcchc12 | Rat | lead(0) | affects expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Lead affects the expression of ZCCHC12 mRNA | CTD | PMID:28903495 | Zcchc12 | Rat | lipopolysaccharide | multiple interactions | ISO | ZCCHC12 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of ZCCHC12 mRNA | CTD | PMID:35811015 | Zcchc12 | Rat | maneb | multiple interactions | ISO | Zcchc12 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of ZCCHC12 mRNA | CTD | PMID:36117858 | Zcchc12 | Rat | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of ZCCHC12 mRNA | CTD | PMID:32035215 | Zcchc12 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of ZCCHC12 mRNA | CTD | PMID:38685447 | Zcchc12 | Rat | methylisothiazolinone | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of ZCCHC12 mRNA | CTD | PMID:31629900 | Zcchc12 | Rat | ozone | multiple interactions | ISO | Zcchc12 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of ZCCHC12 more ... | CTD | PMID:27106289 | Zcchc12 | Rat | paraquat | multiple interactions | ISO | Zcchc12 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of ZCCHC12 mRNA | CTD | PMID:36117858 | Zcchc12 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | ZCCHC12 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of ZCCHC12 mRNA | CTD | PMID:35811015 | Zcchc12 | Rat | silver atom | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Silver results in increased expression of ZCCHC12 mRNA | CTD | PMID:26014281 | Zcchc12 | Rat | silver(0) | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Silver results in increased expression of ZCCHC12 mRNA | CTD | PMID:26014281 | Zcchc12 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of ZCCHC12 mRNA | CTD | PMID:19281266 | Zcchc12 | Rat | tetraphene | increases expression | ISO | Zcchc12 (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of ZCCHC12 mRNA | CTD | PMID:26377693 | Zcchc12 | Rat | thapsigargin | decreases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of ZCCHC12 mRNA | CTD | PMID:22378314 | Zcchc12 | Rat | thapsigargin | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of ZCCHC12 mRNA | CTD | PMID:29453283 | Zcchc12 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ZCCHC12 mRNA | CTD | PMID:34492290 | Zcchc12 | Rat | tunicamycin | decreases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of ZCCHC12 mRNA | CTD | PMID:22378314 | Zcchc12 | Rat | urethane | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Urethane results in increased expression of ZCCHC12 mRNA | CTD | PMID:28818685 | Zcchc12 | Rat | valproic acid | increases expression | ISO | Zcchc12 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of ZCCHC12 mRNA | CTD | PMID:21427059 | Zcchc12 | Rat | valproic acid | increases expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ZCCHC12 mRNA | CTD | PMID:23179753|PMID:28001369 | Zcchc12 | Rat | valproic acid | affects expression | ISO | ZCCHC12 (Homo sapiens) | 6480464 | Valproic Acid affects the 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