Alg13l1 (ALG13, UDP-N-acetylglucosaminyltransferase subunit like 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Alg13l1 (ALG13, UDP-N-acetylglucosaminyltransferase subunit like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Alg13l1
Name: ALG13, UDP-N-acetylglucosaminyltransferase subunit like 1
RGD ID: 1359416
Description: Predicted to enable N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to act upstream of with a positive effect on protein N-linked glycosylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of UDP-N-acetylglucosamine transferase complex. Predicted to be active in cytoplasmic side of endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 36. Orthologous to human ALG13 (ALG13 UDP-N-acetylglucosaminyltransferase subunit); PARTICIPATES IN N-linked glycan biosynthetic pathway; .
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Alg13; ALG13, UDP-N-acetylglucosaminyltransferase subunit; asparagine-linked glycosylation 13; asparagine-linked glycosylation 13 homolog; asparagine-linked glycosylation 13 homolog (S. cerevisiae); glycosyltransferase 28 domain-containing protein 1; LOC300284; similar to RIKEN cDNA 4833435D08; UDP-N-acetylglucosamine transferase subunit ALG13; UDP-N-acetylglucosamine transferase subunit ALG13 homolog
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X112,681,707 - 112,702,932 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX112,681,494 - 112,689,668 (+)EnsemblGRCr8
mRatBN7.2X107,885,039 - 107,906,264 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX107,885,064 - 107,893,002 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX110,028,727 - 110,036,623 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X113,528,441 - 113,536,343 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X111,080,680 - 111,088,578 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X115,561,329 - 115,589,792 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX115,561,332 - 115,619,505 (+)Ensemblrn6Rnor6.0
Rnor_5.0X114,015,086 - 114,036,262 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X34,184,163 - 34,192,061 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX107,272,709 - 107,280,607 (+)NCBICelera
RGSC_v3.1X34,237,632 - 34,245,530 (-)NCBI
Cytogenetic MapXq34NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:21873635   PMID:22681889  


Genomics

Variants

.
Variants in Alg13l1
111 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:23
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000007968
Prediction methods:Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X80434318125434318Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX92979612117740458Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X105468858125434318Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat

Markers in Region
RH132347  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0X119,392,576 - 119,392,766NCBIRnor5.0
Rnor_5.0X114,022,712 - 114,022,902NCBIRnor5.0
Rnor_5.0X119,397,882 - 119,398,072NCBIRnor5.0
RGSC_v3.4X29,575,614 - 29,575,803UniSTSRGSC3.4
RGSC_v3.4X34,184,274 - 34,184,463UniSTSRGSC3.4
CeleraX111,241,164 - 111,241,353UniSTS
CeleraX107,280,307 - 107,280,496UniSTS
Cytogenetic MapXq14UniSTS
RH142021  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X107,883,705 - 107,885,105 (+)MAPPERmRatBN7.2
Rnor_6.0X115,559,960 - 115,561,359NCBIRnor6.0
Rnor_5.0X114,013,717 - 114,015,116UniSTSRnor5.0
RGSC_v3.4X34,192,060 - 34,193,459UniSTSRGSC3.4
CeleraX107,271,311 - 107,272,710UniSTS
RH 3.4 Map71123.91UniSTS
Cytogenetic MapXq14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 12 53 103 57 60 41 64 41 231 129 2 101 43 52 19 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000007968   ⟹   ENSRNOP00000007969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX115,561,358 - 115,568,217 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000075912   ⟹   ENSRNOP00000068280
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX115,561,347 - 115,619,339 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076521   ⟹   ENSRNOP00000068197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX115,561,347 - 115,619,339 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076680   ⟹   ENSRNOP00000068463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX112,681,494 - 112,689,668 (+)Ensembl
mRatBN7.2 EnsemblX107,885,064 - 107,893,002 (+)Ensembl
Rnor_6.0 EnsemblX115,561,332 - 115,569,259 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077034   ⟹   ENSRNOP00000067947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX115,561,332 - 115,589,757 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087859   ⟹   ENSRNOP00000073949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX115,563,038 - 115,619,505 (+)Ensembl
RefSeq Acc Id: NM_001013951   ⟹   NP_001013973
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X112,681,771 - 112,689,669 (+)NCBI
mRatBN7.2X107,885,104 - 107,893,002 (+)NCBI
Rnor_6.0X115,561,358 - 115,569,256 (+)NCBI
Rnor_5.0X114,015,086 - 114,036,262 (+)NCBI
RGSC_v3.4X34,184,163 - 34,192,061 (-)RGD
CeleraX107,272,709 - 107,280,607 (+)RGD
Sequence:
RefSeq Acc Id: XM_017601953   ⟹   XP_017457442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X112,681,707 - 112,702,932 (+)NCBI
mRatBN7.2X107,885,039 - 107,906,264 (+)NCBI
Rnor_6.0X115,561,329 - 115,582,576 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063279883   ⟹   XP_063135953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X112,681,735 - 112,689,669 (+)NCBI
RefSeq Acc Id: NP_001013973   ⟸   NM_001013951
- UniProtKB: Q5I0K7 (UniProtKB/Swiss-Prot),   A6KG91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457442   ⟸   XM_017601953
- Peptide Label: isoform X1
- UniProtKB: A0A096MJN3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067947   ⟸   ENSRNOT00000077034
Ensembl Acc Id: ENSRNOP00000073949   ⟸   ENSRNOT00000087859
Ensembl Acc Id: ENSRNOP00000068280   ⟸   ENSRNOT00000075912
Ensembl Acc Id: ENSRNOP00000007969   ⟸   ENSRNOT00000007968
Ensembl Acc Id: ENSRNOP00000068463   ⟸   ENSRNOT00000076680
Ensembl Acc Id: ENSRNOP00000068197   ⟸   ENSRNOT00000076521
RefSeq Acc Id: XP_063135953   ⟸   XM_063279883
- Peptide Label: isoform X2
- UniProtKB: A6KG92 (UniProtKB/TrEMBL)
Protein Domains
Glycosyl transferase family 28 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5I0K7-F1-model_v2 AlphaFold Q5I0K7 1-165 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701970
Promoter ID:EPDNEW_R12493
Type:multiple initiation site
Name:LOC108349244_1
Description:putative bifunctional UDP-N-acetylglucosamine transferase anddeubiquitinase ALG13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X115,561,332 - 115,561,392EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359416 AgrOrtholog
BioCyc Gene G2FUF-1488 BioCyc
Ensembl Genes ENSRNOG00000005753 Ensembl
  ENSRNOG00000065758 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000076680 ENTREZGENE
  ENSRNOT00000076680.3 UniProtKB/Swiss-Prot
Gene3D-CATH Glycogen Phosphorylase B UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7324702 IMAGE-MGC_LOAD
InterPro Alg13-like UniProtKB/Swiss-Prot
  Glyco_trans_28_C UniProtKB/Swiss-Prot
KEGG Report rno:300284 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109002 IMAGE-MGC_LOAD
NCBI Gene 300284 ENTREZGENE
PANTHER N-ACETYLGLUCOSAMINYLDIPHOSPHODOLICHOL N-ACETYLGLUCOSAMINYLTRANSFERASE UniProtKB/Swiss-Prot
  PTHR12867 UniProtKB/Swiss-Prot
Pfam Glyco_tran_28_C UniProtKB/Swiss-Prot
PhenoGen Alg13l1 PhenoGen
RatGTEx ENSRNOG00000005753 RatGTEx
  ENSRNOG00000065758 RatGTEx
Superfamily-SCOP UDP-Glycosyltransferase/glycogen phosphorylase UniProtKB/Swiss-Prot
UniProt A0A096MJN3 ENTREZGENE
  A6KG91 ENTREZGENE, UniProtKB/TrEMBL
  A6KG92 ENTREZGENE, UniProtKB/TrEMBL
  ALG13_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-01 Alg13l1  ALG13, UDP-N-acetylglucosaminyltransferase subunit like 1  Alg13  ALG13, UDP-N-acetylglucosaminyltransferase subunit  Name and Symbol changed 629549 APPROVED
2014-09-09 Alg13  ALG13, UDP-N-acetylglucosaminyltransferase subunit  Alg13  asparagine-linked glycosylation 13  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-13 Alg13  asparagine-linked glycosylation 13  Alg13  asparagine-linked glycosylation 13 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Alg13  asparagine-linked glycosylation 13 homolog (S. cerevisiae)  LOC300284  similar to RIKEN cDNA 4833435D08  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 LOC300284  similar to RIKEN cDNA 4833435D08      Symbol and Name status set to provisional 70820 PROVISIONAL