Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Vps16 | Rat | dystonia 30 | | ISO | VPS16 (Homo sapiens) | 7240710 | | OMIM | | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Vps16 | Rat | dystonia 30 | | ISO | VPS16 (Homo sapiens) | 7240710 | | OMIM | | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| # | Reference Title | Reference Citation |
| 1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | The interaction of mammalian Class C Vps with nSec-1/Munc18-a and syntaxin 1A regulates pre-synaptic release. | Kim BY, etal., Biochem Biophys Res Commun. 2006 Nov 24;350(3):691-7. doi: 10.1016/j.bbrc.2006.09.104. Epub 2006 Sep 29. |
| 3. | Expression of the mammalian homologue of vacuolar protein sorting 16 (Vps16p) in the mouse and rat brain. | Kim BY, etal., Neurosci Lett 2004 Jan 30;355(3):217-20. |
| 4. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 5. | GOA pipeline | RGD automated data pipeline |
| 6. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 7. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 8. | Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. | Richardson SC, etal., Mol Biol Cell 2004 Mar;15(3):1197-210. Epub 2003 Dec 10. |
| 9. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
| PMID:11382755 | PMID:17897319 | PMID:19109425 | PMID:21411634 | PMID:23901104 | PMID:24550300 | PMID:25266290 | PMID:25783203 |
| Vps16 (Rattus norvegicus - Norway rat) |
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| VPS16 (Homo sapiens - human) |
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| Vps16 (Mus musculus - house mouse) |
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| Vps16 (Chinchilla lanigera - long-tailed chinchilla) |
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| VPS16 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| VPS16 (Canis lupus familiaris - dog) |
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| Vps16 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| VPS16 (Sus scrofa - pig) |
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| VPS16 (Chlorocebus sabaeus - green monkey) |
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| Vps16 (Heterocephalus glaber - naked mole-rat) |
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Variants in Vps16
161 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16 | 12 | 67 | 164 | 91 | 90 | 59 | 92 | 59 | 6 | 356 | 192 | 11 | 143 | 81 | 92 | 31 | 17 | 17 |
| RefSeq Transcripts | NM_001005541 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XR_010064582 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_010064583 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XR_352611 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | BC081963 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| CH473949 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ212033 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| JAXUCZ010000003 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000028821 ⟹ ENSRNOP00000028821 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000099262 ⟹ ENSRNOP00000083827 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000114809 ⟹ ENSRNOP00000095488 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000141135 ⟹ ENSRNOP00000100464 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000151498 ⟹ ENSRNOP00000099250 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001005541 ⟹ NP_001005541 | ||||||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XR_010064582 | ||||||||
| Type: | NON-CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XR_010064583 | ||||||||
| Type: | NON-CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_001005541 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | AAH81963 | (Get FASTA) | NCBI Sequence Viewer |
| EDL80191 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL80192 | (Get FASTA) | NCBI Sequence Viewer | |
| Ensembl Protein | ENSRNOP00000028821 | ||
| ENSRNOP00000028821.3 | |||
| ENSRNOP00000083827.2 | |||
| ENSRNOP00000095488.2 | |||
| ENSRNOP00000099250.1 | |||
| ENSRNOP00000100464.1 |
| RefSeq Acc Id: | NP_001005541 ⟸ NM_001005541 |
| - UniProtKB: | Q642A9 (UniProtKB/TrEMBL), A6HQ90 (UniProtKB/TrEMBL), A0A8I5ZY36 (UniProtKB/TrEMBL), F7FA01 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000028821 ⟸ ENSRNOT00000028821 |
| Ensembl Acc Id: | ENSRNOP00000095488 ⟸ ENSRNOT00000114809 |
| Ensembl Acc Id: | ENSRNOP00000083827 ⟸ ENSRNOT00000099262 |
| Ensembl Acc Id: | ENSRNOP00000100464 ⟸ ENSRNOT00000141135 |
| Ensembl Acc Id: | ENSRNOP00000099250 ⟸ ENSRNOT00000151498 |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-Q642A9-F1-model_v2 | AlphaFold | Q642A9 | 1-839 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| RGD ID: | 13692433 | ||||||||
| Promoter ID: | EPDNEW_R2957 | ||||||||
| Type: | multiple initiation site | ||||||||
| Name: | Vps16_1 | ||||||||
| Description: | VPS16 CORVET/HOPS core subunit | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1359414 | AgrOrtholog |
| BioCyc Gene | G2FUF-47856 | BioCyc |
| Ensembl Genes | ENSRNOG00000021222 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000028821 | ENTREZGENE |
| ENSRNOT00000028821.6 | UniProtKB/TrEMBL | |
| ENSRNOT00000099262.2 | UniProtKB/TrEMBL | |
| ENSRNOT00000114809.2 | UniProtKB/TrEMBL | |
| ENSRNOT00000141135.1 | UniProtKB/TrEMBL | |
| ENSRNOT00000151498.1 | UniProtKB/TrEMBL | |
| Gene3D-CATH | 1.10.150.780 | UniProtKB/TrEMBL |
| IMAGE_CLONE | IMAGE:7124985 | IMAGE-MGC_LOAD |
| InterPro | VPS16 | UniProtKB/TrEMBL |
| Vps16_C | UniProtKB/TrEMBL | |
| Vps16_C_sf | UniProtKB/TrEMBL | |
| Vps16_N | UniProtKB/TrEMBL | |
| KEGG Report | rno:296159 | UniProtKB/TrEMBL |
| MGC_CLONE | MGC:94090 | IMAGE-MGC_LOAD |
| NCBI Gene | 296159 | ENTREZGENE |
| PANTHER | PTHR12811 | UniProtKB/TrEMBL |
| VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG | UniProtKB/TrEMBL | |
| Pfam | Vps16_C | UniProtKB/TrEMBL |
| Vps16_N | UniProtKB/TrEMBL | |
| PhenoGen | Vps16 | PhenoGen |
| PIRSF | VPS16 | UniProtKB/TrEMBL |
| RatGTEx | ENSRNOG00000021222 | RatGTEx |
| UniProt | A0A8I5ZY36 | ENTREZGENE, UniProtKB/TrEMBL |
| A0A8I6GL61_RAT | UniProtKB/TrEMBL | |
| A0ABK0KX70_RAT | UniProtKB/TrEMBL | |
| A0ABK0LF41_RAT | UniProtKB/TrEMBL | |
| A6HQ90 | ENTREZGENE, UniProtKB/TrEMBL | |
| A6HQ91_RAT | UniProtKB/TrEMBL | |
| F7FA01 | ENTREZGENE, UniProtKB/TrEMBL | |
| Q642A9 | ENTREZGENE | |
| UniProt Secondary | Q642A9 | UniProtKB/TrEMBL |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2019-04-02 | Vps16 | VPS16 core subunit of CORVET and HOPS complexes | Vps16 | VPS16 CORVET/HOPS core subunit | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2015-11-25 | Vps16 | VPS16 CORVET/HOPS core subunit | Vps16 | vacuolar protein sorting 16 homolog (S. cerevisiae) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-09-25 | Vps16 | vacuolar protein sorting 16 homolog (S. cerevisiae) | Vps16 | vacuolar protein sorting 16 (yeast) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2006-03-30 | Vps16 | vacuolar protein sorting 16 (yeast) | vacuolar protein sorting 16 | Name updated | 1299863 | APPROVED | |
| 2005-07-29 | Vps16 | vacuolar protein sorting 16 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |