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Gene: Ficd (FIC domain protein adenylyltransferase) Rattus norvegicus

Analyze

Symbol:

Ficd

Name:

FIC domain protein adenylyltransferase

RGD ID:

1359391

Description:

Predicted to enable several functions, including AMPylase activity; ATP binding activity; and Hsp70 protein binding activity. Predicted to be involved in several processes, including protein adenylylation; protein deadenylylation; and regulation of IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human FICD (FIC domain protein adenylyltransferase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; azoxystrobin; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

adenosine monophosphate-protein transferase FICD; AMPylator FICD; de-AMPylase FICD; FIC domain containing; FIC domain-containing protein; huntingtin interactor protein E; LOC288741

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FICD (FIC domain protein adenylyltransferase)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Ficd (FIC domain containing)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ficd (FIC domain protein adenylyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FICD (FIC domain protein adenylyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FICD (FIC domain protein adenylyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ficd (FIC domain protein adenylyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FICD (FIC domain protein adenylyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FICD (FIC domain protein adenylyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ficd (FIC domain protein adenylyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ficd (FIC domain protein adenylyltransferase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	FICD (FIC domain protein adenylyltransferase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ficd (FIC domain containing)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ficd (FIC domain containing)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Fic	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	fic-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ficd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	48,549,737 - 48,554,626 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	48,549,737 - 48,554,626 (-)	Ensembl				GRCr8
mRatBN7.2	12	42,889,195 - 42,894,090 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	42,889,194 - 42,894,070 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	44,057,069 - 44,059,923 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	44,670,665 - 44,673,519 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	43,731,196 - 43,734,050 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	48,658,283 - 48,663,175 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	48,658,283 - 48,663,143 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	50,440,239 - 50,445,246 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	43,924,661 - 43,927,515 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	44,492,066 - 44,494,920 (-)	NCBI		Celera
RGSC_v3.1	12	43,788,050 - 43,790,903 (-)	NCBI
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hereditary spastic paraplegia 92 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-palmitoylglycerol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

azoxystrobin (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

celastrol (ISO)

chlorpyrifos (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

gedunin (ISO)

glyphosate (EXP)

imidacloprid (EXP)

iron dichloride (ISO)

metformin (EXP)

methyl methanesulfonate (ISO)

nitrofen (EXP)

paracetamol (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (ISO)

propiconazole (ISO)

resveratrol (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tamoxifen (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (ISO)

thiabendazole (EXP)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

tunicamycin (ISO)

urethane (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein adenylylation (IBA,ISO,ISS)

protein deadenylylation (ISS)

regulation of IRE1-mediated unfolded protein response (IBA,IEA,ISO,ISS)

response to endoplasmic reticulum stress (ISO,ISS)

response to unfolded protein (IEA)

Cellular Component

endoplasmic reticulum (IBA,ISO,ISS)

endoplasmic reticulum membrane (IEA,ISO,ISS)

membrane (IEA)

Molecular Function

AMPylase activity (IBA,IEA,ISO,ISS)

ATP binding (IEA,ISO,ISS)

Hsp70 protein binding (IEA,ISO)

hydrolase activity (IEA)

identical protein binding (ISO)

nucleotide binding (IEA)

nucleotidyltransferase activity (IEA)

protein adenylylhydrolase activity (IEA,ISO,ISS)

protein binding (ISO)

protein homodimerization activity (ISO,ISS)

protein-folding chaperone binding (ISO,ISS)

transferase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Huntingtin interacts with a family of WW domain proteins.	Faber PW, etal., Hum Mol Genet 1998 Sep;7(9):1463-74.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:19362538	PMID:22266942	PMID:25435325	PMID:25601083

Genomics

Comparative Map Data

Ficd
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	48,549,737 - 48,554,626 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	48,549,737 - 48,554,626 (-)	Ensembl				GRCr8
mRatBN7.2	12	42,889,195 - 42,894,090 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	42,889,194 - 42,894,070 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	44,057,069 - 44,059,923 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	44,670,665 - 44,673,519 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	43,731,196 - 43,734,050 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	48,658,283 - 48,663,175 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	48,658,283 - 48,663,143 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	50,440,239 - 50,445,246 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	43,924,661 - 43,927,515 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	44,492,066 - 44,494,920 (-)	NCBI		Celera
RGSC_v3.1	12	43,788,050 - 43,790,903 (-)	NCBI
Cytogenetic Map	12	q16	NCBI

FICD
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	108,515,277 - 108,521,210 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	108,513,710 - 108,525,837 (+)	Ensembl			hg38	GRCh38
GRCh37	12	108,909,054 - 108,914,987 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	107,433,181 - 107,437,510 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	12	108,578,435 - 108,582,764 (+)	NCBI		Celera
Cytogenetic Map	12	q23.3	NCBI
HuRef	12	105,973,609 - 105,977,938 (+)	NCBI		HuRef
CHM1_1	12	108,875,263 - 108,879,592 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	108,484,639 - 108,490,575 (+)	NCBI		T2T-CHM13v2.0

Ficd
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	113,873,821 - 113,878,670 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	113,873,864 - 113,878,661 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	113,735,758 - 113,740,607 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	113,735,803 - 113,740,600 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	114,185,791 - 114,190,616 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	113,996,802 - 114,001,599 (+)	NCBI		MGSCv36	mm8
Celera	5	110,836,905 - 110,841,730 (+)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	55.55	NCBI

Ficd
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	9,795,116 - 9,799,006 (+)	Ensembl
ChiLan1.0	NW_004955455	9,794,919 - 9,799,006 (+)	NCBI	ChiLan1.0	ChiLan1.0

FICD
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	116,574,233 - 116,581,371 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	116,570,629 - 116,577,769 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	106,086,792 - 106,092,765 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	109,482,945 - 109,488,958 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	109,482,945 - 109,488,958 (+)	Ensembl			panPan2	panpan1.1

FICD
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	18,347,393 - 18,353,081 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	18,348,526 - 18,353,665 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	17,446,758 - 17,452,444 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	18,693,783 - 18,699,469 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	18,694,296 - 18,700,371 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	17,655,763 - 17,661,436 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	18,681,621 - 18,687,306 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	18,703,164 - 18,708,843 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ficd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	145,026,455 - 145,031,802 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936769	444,051 - 452,149 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936769	444,122 - 448,016 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FICD
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	42,260,069 - 42,266,858 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	42,261,505 - 42,269,184 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	44,806,796 - 44,812,203 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FICD
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	103,709,271 - 103,715,187 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	103,709,173 - 103,715,172 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	141,379,923 - 141,385,911 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ficd
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	11,767,020 - 11,773,971 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	11,767,059 - 11,773,971 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ficd
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	40,235,661 - 40,239,167 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	114
Count of miRNA genes:	94
Interacting mature miRNAs:	96
Transcripts:	ENSRNOT00000000892
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37764145	51558799	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	33700432	51558799	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	44139558	52308831	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001010946	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769320	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769321	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC128917	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079197	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000082809 ⟹ ENSRNOP00000073778

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	48,550,266 - 48,554,626 (-)	Ensembl
mRatBN7.2 Ensembl	12	42,889,194 - 42,894,070 (-)	Ensembl
Rnor_6.0 Ensembl	12	48,658,283 - 48,663,143 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000142461 ⟹ ENSRNOP00000098765

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	48,549,737 - 48,553,975 (-)	Ensembl

RefSeq Acc Id:

NM_001010946 ⟹ NP_001010946

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,551,121 - 48,553,975 (-)	NCBI
mRatBN7.2	12	42,890,579 - 42,893,433 (-)	NCBI
Rnor_6.0	12	48,659,667 - 48,662,521 (-)	NCBI
Rnor_5.0	12	50,440,239 - 50,445,246 (-)	NCBI
RGSC_v3.4	12	43,924,661 - 43,927,515 (-)	RGD
Celera	12	44,492,066 - 44,494,920 (-)	RGD

Sequence:

show sequence

CTAGGGCTGACAAGTCCCTGACTTCACTTTTCTGAGCTCTTACTGCATCTGGAGAGAGCGCTGT
GGAAACATCACCTCCTCGGGTTGTAGTCTGAGATTATGGACGTTAATGTATGTAGGAAGTGCTC
TGTAAACGCCTTAGATTTCTATCTTGCTACCCAGGAGCAGCTAGGAGTTAGTTAGGATGAGTCT
TTCCACCATGAGAGCTCTCACCTTCCCCCTTTCCCTGGTCCCTAGTGAATTAGAAGGTGTGGAG
ATTCTCCATGTTGGTCTCTCCATCTGAAATCACAGTTACTGGGAGCAGGTCCACTCTCCTCCCT
CATTCTTTCCGACGCTTGGTTCCTCGTAGATTCTGCTTTCCTCTGAGACGGGATATGCGCCCTG
GGCCCGGCCCTTAGTCCAGATGATACTCATGCCGATGGCGTCAGTGGTGGCAGTGGCTGAACCC
AAATGGGTCTCAGTCTGGGGCCGTTTCCTGTGGATGACACTGCTGAGCATGGCTCTGGGGTCAC
TGCTGGCCCTGCTGCTGCCACTGGGAGCTGTGGAAGAACAGTGTCTGGCTGTGCTCAGAGGCTT
CCACCTGCTCAGGAGCAAACTGGACAGGGCACAGCATGTGGTCACCAAGTGCACCAGCCCATCT
ACGGAGCTCAGTGTCACCTCCAGGGACGCAGGGCTGCTGACGGTCAAGACTAAGGCGTCTCCAG
CAGGGAAACTGGAAGCCAAGGCCGCACTAAACCAAGCCCTAGAGATGAAGCGCCAAGGCAAGAG
GGGCAAAGCGCACAAGCTCTTCCTGCATGCCCTCAAGATGGACCCTGGCTTCGTAGACGCCCTC
AATGAGCTCGGCATCTTCTCAGAAGAGGACAAGGACATCATCCAGGCAGATTACCTCTACACTA
GGGCCCTGACCATTTCGCCCTTCCACGAGAAAGCACTGATCAACCGGGACCGGACGCTGCCACT
GGTGGAGGAAATCGACCAGAGGTACTTCAGCGTCCTTGACAGCAAAGTGAGGAAGGTAATGTCC
ATCCCTAAGGGGAGCTCAGCGCTCCGCAGGGTCATGGAGGAGACCTACTACCATCACATCTACC
ACACTGTGGCTATCGAGGGCAACACCCTCACTCTCGCAGAGATCAGGCACATCCTGGAGACACG
CTATGCCGTGCCAGGGAAGAGCTTGGAGGAGCAAAACGAGGTGATCGGCATGCACGCGGCCATG
AAGTACATCAACAGTACCCTGGTCTCCCGCATCGGGTCCGTCACCATTGACCACATGCTGGAGA
TCCACAGGAGGGTCCTGGGGTACGTGGACCCAGTGGAGGCGGGCAGGTTTCGGAGGACCCAGGT
CCTGGTGGGACACCACATCCCACCCCACCCCCGGGACGTGGAGAAGCAGATGCAGGAGTTCACA
CAGTGGCTCAATTCGGAGGACGCCATGAACCTGCACCCGGTTGAGTTCGCAGCCTTAGCCCATT
ACAAACTGGTGTACATCCACCCTTTCATCGATGGCAATGGGAGGACCTCCCGCCTGCTGATGAA
CCTGATCCTGATGCAGGCAGGGTACCCGCCCATCACCATACGCAAGGAGCAGAGGTCAGAGTAC
TACCATGTGCTGGAAGTCGCCAACGAGGGTGACGTGCGGCCATTCATCCGCTTCATAGCCAAGT
GTACGGAAGTCACACTGGACACATTGCTCCTCGCCACCACCGAGTACTCTGCAGCACTGCCAGA
AGCCCAGCCCAACCACTCTGGGTTCAAGGAGACACTTCCTGTGAGGCCTTAACCACCAGCCCTC
CCATGGCGCCCTGAGAAGGCCTTTCTAGAAACAGTTCTCCCCAGTAGCAAAAGGAGACCCTTAA
ACATTCTTTACCTCCAGGTGTTTTTCAGTTGAGAAAGAAAACTAAATTATTAAGCCTGTCTTTA
GGATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008769320 ⟹ XP_008767542

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,549,737 - 48,554,626 (-)	NCBI
mRatBN7.2	12	42,889,195 - 42,894,090 (-)	NCBI
Rnor_6.0	12	48,658,283 - 48,663,175 (-)	NCBI

Sequence:

show sequence

CGGAGGGCGGGCCCGGCGACCGCGGCTGCTAGGAACGGCCGCGCGGCCTCAGATGGTGCGGCGG
GCGCGAACCTTGGGCCGATCCGCAGAGAGACCTTACGGCAGCCTCAGTTTCCCACTTCGGGAGT
AAGCCCAGCATGCTGGGCTCAAGCAGCTGCACAGGCCGCGCGAAGTGATGACGTGACGGGTAAG
GCCCTGGAACTCCGGCGCCGCCTGTCAGAACCGCGTCATCCCTCGTCTGTAAACTGGAGCCACA
GATTCTGCTTTCCTCTGAGACGGGATATGCGCCCTGGGCCCGGCCCTTAGTCCAGATGATACTC
ATGCCGATGGCGTCAGTGGTGGCAGTGGCTGAACCCAAATGGGTCTCAGTCTGGGGCCGTTTCC
TGTGGATGACACTGCTGAGCATGGCTCTGGGGTCACTGCTGGCCCTGCTGCTGCCACTGGGAGC
TGTGGAAGAACAGTGTCTGGCTGTGCTCAGAGGCTTCCACCTGCTCAGGAGCAAACTGGACAGG
GCACAGCATGTGGTCACCAAGTGCACCAGCCCATCTACGGAGCTCAGTGTCACCTCCAGGGACG
CAGGGCTGCTGACGGTCAAGACTAAGGCGTCTCCAGCAGGGAAACTGGAAGCCAAGGCCGCACT
AAACCAAGCCCTAGAGATGAAGCGCCAAGGCAAGAGGGGCAAAGCGCACAAGCTCTTCCTGCAT
GCCCTCAAGATGGACCCTGGCTTCGTAGACGCCCTCAATGAGCTCGGCATCTTCTCAGAAGAGG
ACAAGGACATCATCCAGGCAGATTACCTCTACACTAGGGCCCTGACCATTTCGCCCTTCCACGA
GAAAGCACTGATCAACCGGGACCGGACGCTGCCACTGGTGGAGGAAATCGACCAGAGGTACTTC
AGCGTCCTTGACAGCAAAGTGAGGAAGGTAATGTCCATCCCTAAGGGGAGCTCAGCGCTCCGCA
GGGTCATGGAGGAGACCTACTACCATCACATCTACCACACTGTGGCTATCGAGGGCAACACCCT
CACTCTCGCAGAGATCAGGCACATCCTGGAGACACGCTATGCCGTGCCAGGGAAGAGCTTGGAG
GAGCAAAACGAGGTGATCGGCATGCACGCGGCCATGAAGTACATCAACAGTACCCTGGTCTCCC
GCATCGGGTCCGTCACCATTGACCACATGCTGGAGATCCACAGGAGGGTCCTGGGGTACGTGGA
CCCAGTGGAGGCGGGCAGGTTTCGGAGGACCCAGGTCCTGGTGGGACACCACATCCCACCCCAC
CCCCGGGACGTGGAGAAGCAGATGCAGGAGTTCACACAGTGGCTCAATTCGGAGGACGCCATGA
ACCTGCACCCGGTTGAGTTCGCAGCCTTAGCCCATTACAAACTGGTGTACATCCACCCTTTCAT
CGATGGCAATGGGAGGACCTCCCGCCTGCTGATGAACCTGATCCTGATGCAGGCAGGGTACCCG
CCCATCACCATACGCAAGGAGCAGAGGTCAGAGTACTACCATGTGCTGGAAGTCGCCAACGAGG
GTGACGTGCGGCCATTCATCCGCTTCATAGCCAAGTGTACGGAAGTCACACTGGACACATTGCT
CCTCGCCACCACCGAGTACTCTGCAGCACTGCCAGAAGCCCAGCCCAACCACTCTGGGTTCAAG
GAGACACTTCCTGTGAGGCCTTAACCACCAGCCCTCCCATGGCGCCCTGAGAAGGCCTTTCTAG
AAACAGTTCTCCCCAGTAGCAAAAGGAGACCCTTAAACATTCTTTACCTCCAGGTGTTTTTCAG
TTGAGAAAGAAAACTAAATTATTAAGCCTGTCTTTAGGATAATTTATAGTTCAGCCAAGTTATT
TATTTTTTTACCTTTTTGGTGAGCTAGAGGTGCTGAGACCAACCCTTATGGTGACCCCAGCACC
CAGTAGGGCAGCAGTGCTTTCCTAATGTCCTGAGCCTGGGTGCCTAGACAGAATTTGCACTAAG
GGTGGAGGCAGGGAGCCAGATCTGTGACATGGAGCCCAGGGCCACAGGGGTCACTGGATACCTT
GGAGGTCCTGTGACCTCAGAAGGCAGAACTGCCCTGCGCTGAGGCCGGCCTTCACTCCTGAGAG
GCTGTGGCAGCAGCTTCCACAGCAGGCAGCGCAGCCCTTGGACACAGGAAGCCAACGTTGCCAT
CTCCGTAGTTGACTGCAGATTCCAGGGACCCCCTGAGCTACTAACTTTTAACCTGAGTGCCAGG
GGGTGGTACTTCCCTACCCAGCCTGTTCTGAGGGCAGAGGGCGGGCAGCATGGCTCTTTCTTAT
CTTTGTCCTGGACTTCACTCGCATCCGCTGAGGCTGAAAGCTCTCCATGCTTGACAACCTACCC
CATCACGCCACAGGGCGGGTTTGCCTTCACCTCCCACTCAGTCTCCTGCACAGAGACCTTAAGG
GTCCTGTGAGGACCTGGAGGTGAGGTAGAACACTACCCAGCATGCACCACACCCTAGGCACCTC
CCTTAACATTACAAGGGAATGTGTCTGAAGTACCACGCCAAACCCAAACAAGCAGTTCTGATAA
GAGTTAAAACGAGCAAACACCCGTGTCCACAACCTGGCCTCTCCCCTTCTGCCCTGTGGTTTTA
AACCCTCTTCCCCTCTAACGCCACCACAGGGTCCAGCGTCCCCACGGGTATGTAGACTGTCTTG
GAGTGGCCTTGTTCTAGTGACTTGTGAAGTGATGGTGTCGCGTCTGATAGACACGTTTCCAGTT
GTCCTCTTAGAAGACAATAAACGCTCTTCAATCATTTATGGCTAAGCGCCAGTTTGATTGCTGC
TATTCAGTCGCCATGGCCAAGTCACTGGACCGTGTTCTGGGACGGCCTCCTCTGTCCCAGCATG
CTGTGCTTTGAATGGTAAACCAGCTGCCAACCCATGTATCCAGCGTCTAGAAAGATACCCCAGC
AGTTTTCTGACGGATTGAGAAAAATGTGTGAAAAATGTGTGTGTCTGCAAGCGTGCCACACCAC
CAACAGCTCTGCAAGGGCTGGGTGGCAGAGTCACCCGGCAGATGTCACCCAGAGACACTGCATC
GATTGCAGCCCCAAGCTCCCAGCTCTTCTCTGCACACCAAATCTCACGGGAGGCTCACTTTGGC
CTGTGGTGAGAACCTGCACTTTAGCTACGTGTGAAAATATTTTAACAAGTTCCTGGTTCTAATA
AAGTATTTTATTACATAA

hide sequence

RefSeq Acc Id:

XM_008769321 ⟹ XP_008767543

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,549,737 - 48,554,626 (-)	NCBI
mRatBN7.2	12	42,889,195 - 42,894,090 (-)	NCBI
Rnor_6.0	12	48,658,283 - 48,663,175 (-)	NCBI

Sequence:

show sequence

CGGAGGGCGGGCCCGGCGACCGCGGCTGCTAGGAACGGCCGCGCGGCCTCAGATGGTGCGGCGG
GCGCGAACCTTGGGCCGATCCGCAGAGAGACCTTACGGCAGCCTCAGTTTCCCACTTCGGGAGT
AAGCCCAGCATGCTGGGCTCAAGCAGCTGCACAGGCCGCGCGAAGTGATGACGTGACGGATTCT
GCTTTCCTCTGAGACGGGATATGCGCCCTGGGCCCGGCCCTTAGTCCAGATGATACTCATGCCG
ATGGCGTCAGTGGTGGCAGTGGCTGAACCCAAATGGGTCTCAGTCTGGGGCCGTTTCCTGTGGA
TGACACTGCTGAGCATGGCTCTGGGGTCACTGCTGGCCCTGCTGCTGCCACTGGGAGCTGTGGA
AGAACAGTGTCTGGCTGTGCTCAGAGGCTTCCACCTGCTCAGGAGCAAACTGGACAGGGCACAG
CATGTGGTCACCAAGTGCACCAGCCCATCTACGGAGCTCAGTGTCACCTCCAGGGACGCAGGGC
TGCTGACGGTCAAGACTAAGGCGTCTCCAGCAGGGAAACTGGAAGCCAAGGCCGCACTAAACCA
AGCCCTAGAGATGAAGCGCCAAGGCAAGAGGGGCAAAGCGCACAAGCTCTTCCTGCATGCCCTC
AAGATGGACCCTGGCTTCGTAGACGCCCTCAATGAGCTCGGCATCTTCTCAGAAGAGGACAAGG
ACATCATCCAGGCAGATTACCTCTACACTAGGGCCCTGACCATTTCGCCCTTCCACGAGAAAGC
ACTGATCAACCGGGACCGGACGCTGCCACTGGTGGAGGAAATCGACCAGAGGTACTTCAGCGTC
CTTGACAGCAAAGTGAGGAAGGTAATGTCCATCCCTAAGGGGAGCTCAGCGCTCCGCAGGGTCA
TGGAGGAGACCTACTACCATCACATCTACCACACTGTGGCTATCGAGGGCAACACCCTCACTCT
CGCAGAGATCAGGCACATCCTGGAGACACGCTATGCCGTGCCAGGGAAGAGCTTGGAGGAGCAA
AACGAGGTGATCGGCATGCACGCGGCCATGAAGTACATCAACAGTACCCTGGTCTCCCGCATCG
GGTCCGTCACCATTGACCACATGCTGGAGATCCACAGGAGGGTCCTGGGGTACGTGGACCCAGT
GGAGGCGGGCAGGTTTCGGAGGACCCAGGTCCTGGTGGGACACCACATCCCACCCCACCCCCGG
GACGTGGAGAAGCAGATGCAGGAGTTCACACAGTGGCTCAATTCGGAGGACGCCATGAACCTGC
ACCCGGTTGAGTTCGCAGCCTTAGCCCATTACAAACTGGTGTACATCCACCCTTTCATCGATGG
CAATGGGAGGACCTCCCGCCTGCTGATGAACCTGATCCTGATGCAGGCAGGGTACCCGCCCATC
ACCATACGCAAGGAGCAGAGGTCAGAGTACTACCATGTGCTGGAAGTCGCCAACGAGGGTGACG
TGCGGCCATTCATCCGCTTCATAGCCAAGTGTACGGAAGTCACACTGGACACATTGCTCCTCGC
CACCACCGAGTACTCTGCAGCACTGCCAGAAGCCCAGCCCAACCACTCTGGGTTCAAGGAGACA
CTTCCTGTGAGGCCTTAACCACCAGCCCTCCCATGGCGCCCTGAGAAGGCCTTTCTAGAAACAG
TTCTCCCCAGTAGCAAAAGGAGACCCTTAAACATTCTTTACCTCCAGGTGTTTTTCAGTTGAGA
AAGAAAACTAAATTATTAAGCCTGTCTTTAGGATAATTTATAGTTCAGCCAAGTTATTTATTTT
TTTACCTTTTTGGTGAGCTAGAGGTGCTGAGACCAACCCTTATGGTGACCCCAGCACCCAGTAG
GGCAGCAGTGCTTTCCTAATGTCCTGAGCCTGGGTGCCTAGACAGAATTTGCACTAAGGGTGGA
GGCAGGGAGCCAGATCTGTGACATGGAGCCCAGGGCCACAGGGGTCACTGGATACCTTGGAGGT
CCTGTGACCTCAGAAGGCAGAACTGCCCTGCGCTGAGGCCGGCCTTCACTCCTGAGAGGCTGTG
GCAGCAGCTTCCACAGCAGGCAGCGCAGCCCTTGGACACAGGAAGCCAACGTTGCCATCTCCGT
AGTTGACTGCAGATTCCAGGGACCCCCTGAGCTACTAACTTTTAACCTGAGTGCCAGGGGGTGG
TACTTCCCTACCCAGCCTGTTCTGAGGGCAGAGGGCGGGCAGCATGGCTCTTTCTTATCTTTGT
CCTGGACTTCACTCGCATCCGCTGAGGCTGAAAGCTCTCCATGCTTGACAACCTACCCCATCAC
GCCACAGGGCGGGTTTGCCTTCACCTCCCACTCAGTCTCCTGCACAGAGACCTTAAGGGTCCTG
TGAGGACCTGGAGGTGAGGTAGAACACTACCCAGCATGCACCACACCCTAGGCACCTCCCTTAA
CATTACAAGGGAATGTGTCTGAAGTACCACGCCAAACCCAAACAAGCAGTTCTGATAAGAGTTA
AAACGAGCAAACACCCGTGTCCACAACCTGGCCTCTCCCCTTCTGCCCTGTGGTTTTAAACCCT
CTTCCCCTCTAACGCCACCACAGGGTCCAGCGTCCCCACGGGTATGTAGACTGTCTTGGAGTGG
CCTTGTTCTAGTGACTTGTGAAGTGATGGTGTCGCGTCTGATAGACACGTTTCCAGTTGTCCTC
TTAGAAGACAATAAACGCTCTTCAATCATTTATGGCTAAGCGCCAGTTTGATTGCTGCTATTCA
GTCGCCATGGCCAAGTCACTGGACCGTGTTCTGGGACGGCCTCCTCTGTCCCAGCATGCTGTGC
TTTGAATGGTAAACCAGCTGCCAACCCATGTATCCAGCGTCTAGAAAGATACCCCAGCAGTTTT
CTGACGGATTGAGAAAAATGTGTGAAAAATGTGTGTGTCTGCAAGCGTGCCACACCACCAACAG
CTCTGCAAGGGCTGGGTGGCAGAGTCACCCGGCAGATGTCACCCAGAGACACTGCATCGATTGC
AGCCCCAAGCTCCCAGCTCTTCTCTGCACACCAAATCTCACGGGAGGCTCACTTTGGCCTGTGG
TGAGAACCTGCACTTTAGCTACGTGTGAAAATATTTTAACAAGTTCCTGGTTCTAATAAAGTAT
TTTATTACATAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001010946	(Get FASTA)	NCBI Sequence Viewer
	XP_008767542	(Get FASTA)	NCBI Sequence Viewer
	XP_008767543	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79197	(Get FASTA)	NCBI Sequence Viewer
	EDM13967	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000073778
GenBank Protein	Q6AY47	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001010946 ⟸ NM_001010946

- UniProtKB:

Q6AY47 (UniProtKB/Swiss-Prot), A6J228 (UniProtKB/TrEMBL), A0A8L2UR38 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MILMPMASVVAVAEPKWVSVWGRFLWMTLLSMALGSLLALLLPLGAVEEQCLAVLRGFHLLRSK
LDRAQHVVTKCTSPSTELSVTSRDAGLLTVKTKASPAGKLEAKAALNQALEMKRQGKRGKAHKL
FLHALKMDPGFVDALNELGIFSEEDKDIIQADYLYTRALTISPFHEKALINRDRTLPLVEEIDQ
RYFSVLDSKVRKVMSIPKGSSALRRVMEETYYHHIYHTVAIEGNTLTLAEIRHILETRYAVPGK
SLEEQNEVIGMHAAMKYINSTLVSRIGSVTIDHMLEIHRRVLGYVDPVEAGRFRRTQVLVGHHI
PPHPRDVEKQMQEFTQWLNSEDAMNLHPVEFAALAHYKLVYIHPFIDGNGRTSRLLMNLILMQA
GYPPITIRKEQRSEYYHVLEVANEGDVRPFIRFIAKCTEVTLDTLLLATTEYSAALPEAQPNHS
GFKETLPVRP

hide sequence

RefSeq Acc Id:	XP_008767543 ⟸ XM_008769321
- Peptide Label:	isoform X1
- UniProtKB:	Q6AY47 (UniProtKB/Swiss-Prot), A6J228 (UniProtKB/TrEMBL), A0A8L2UR38 (UniProtKB/TrEMBL)
- Sequence:	show sequence MILMPMASVVAVAEPKWVSVWGRFLWMTLLSMALGSLLALLLPLGAVEEQCLAVLRGFHLLRSK LDRAQHVVTKCTSPSTELSVTSRDAGLLTVKTKASPAGKLEAKAALNQALEMKRQGKRGKAHKL FLHALKMDPGFVDALNELGIFSEEDKDIIQADYLYTRALTISPFHEKALINRDRTLPLVEEIDQ RYFSVLDSKVRKVMSIPKGSSALRRVMEETYYHHIYHTVAIEGNTLTLAEIRHILETRYAVPGK SLEEQNEVIGMHAAMKYINSTLVSRIGSVTIDHMLEIHRRVLGYVDPVEAGRFRRTQVLVGHHI PPHPRDVEKQMQEFTQWLNSEDAMNLHPVEFAALAHYKLVYIHPFIDGNGRTSRLLMNLILMQA GYPPITIRKEQRSEYYHVLEVANEGDVRPFIRFIAKCTEVTLDTLLLATTEYSAALPEAQPNHS GFKETLPVRP hide sequence

RefSeq Acc Id:	XP_008767542 ⟸ XM_008769320
- Peptide Label:	isoform X1
- UniProtKB:	Q6AY47 (UniProtKB/Swiss-Prot), A6J228 (UniProtKB/TrEMBL), A0A8L2UR38 (UniProtKB/TrEMBL)
- Sequence:	show sequence MILMPMASVVAVAEPKWVSVWGRFLWMTLLSMALGSLLALLLPLGAVEEQCLAVLRGFHLLRSK LDRAQHVVTKCTSPSTELSVTSRDAGLLTVKTKASPAGKLEAKAALNQALEMKRQGKRGKAHKL FLHALKMDPGFVDALNELGIFSEEDKDIIQADYLYTRALTISPFHEKALINRDRTLPLVEEIDQ RYFSVLDSKVRKVMSIPKGSSALRRVMEETYYHHIYHTVAIEGNTLTLAEIRHILETRYAVPGK SLEEQNEVIGMHAAMKYINSTLVSRIGSVTIDHMLEIHRRVLGYVDPVEAGRFRRTQVLVGHHI PPHPRDVEKQMQEFTQWLNSEDAMNLHPVEFAALAHYKLVYIHPFIDGNGRTSRLLMNLILMQA GYPPITIRKEQRSEYYHVLEVANEGDVRPFIRFIAKCTEVTLDTLLLATTEYSAALPEAQPNHS GFKETLPVRP hide sequence

Ensembl Acc Id:

ENSRNOP00000073778 ⟸ ENSRNOT00000082809

Ensembl Acc Id:

ENSRNOP00000098765 ⟸ ENSRNOT00000142461

Protein Domains

Fido

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AY47-F1-model_v2	AlphaFold	Q6AY47	1-458	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698722

Promoter ID:

EPDNEW_R9246

Type:

initiation region

Name:

Ficd_1

Description:

FIC domain containing

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	48,663,144 - 48,663,204	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359391	AgrOrtholog
BioCyc Gene	G2FUF-18923	BioCyc
Ensembl Genes	ENSRNOG00000059799	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000082809	ENTREZGENE
Gene3D-CATH	1.10.3290.10	UniProtKB/Swiss-Prot
	1.25.40.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7131463	IMAGE-MGC_LOAD
InterPro	Fido	UniProtKB/Swiss-Prot
	Fido-like_dom_sf	UniProtKB/Swiss-Prot
	Fido_containing	UniProtKB/Swiss-Prot
	TPR-like_helical_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:288741	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94249	IMAGE-MGC_LOAD
NCBI Gene	288741	ENTREZGENE
PANTHER	PROTEIN ADENYLYLTRANSFERASE FICD	UniProtKB/Swiss-Prot
	PTHR13504	UniProtKB/Swiss-Prot
Pfam	Fic	UniProtKB/Swiss-Prot
PhenoGen	Ficd	PhenoGen
PROSITE	FIDO	UniProtKB/Swiss-Prot
	TPR_REGION	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000059799	RatGTEx
Superfamily-SCOP	SSF140931	UniProtKB/Swiss-Prot
	SSF48452	UniProtKB/Swiss-Prot
UniProt	A0A8L2UR38	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L4H8_RAT	UniProtKB/TrEMBL
	A6J228	ENTREZGENE, UniProtKB/TrEMBL
	FICD_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-01-17	Ficd	FIC domain protein adenylyltransferase	Ficd	FIC domain containing	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-04	Ficd	FIC domain containing	LOC288741	huntingtin interactor protein E	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-29	LOC288741	huntingtin interactor protein E			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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