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Gene: Mageh1 (MAGE family member H1) Rattus norvegicus

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Symbol:

Mageh1

Name:

MAGE family member H1

RGD ID:

1359316

Description:

Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MAGEH1 (MAGE family member H1); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

MAGE-H1 antigen; melanoma antigen, family H, 1; melanoma-associated antigen H1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MAGEH1 (MAGE family member H1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Mageh1 (MAGE family member H1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mageh1 (MAGE family member H1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MAGEH1 (MAGE family member H1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MAGEH1 (MAGE family member H1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mageh1 (MAGE family member H1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MAGEH1 (MAGE family member H1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MAGEH1 (MAGE family member H1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Mageh1 (MAGE family member H1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NR2E1 (nuclear receptor subfamily 2 group E member 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	MAGEH1 (MAGE family member H1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mageh1 (MAGE family member H1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	MAGE	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	MAGE	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	NSE3	Alliance	DIOPT (Hieranoid\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	21,725,709 - 21,726,965 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	21,718,669 - 21,727,219 (+)	Ensembl				GRCr8
mRatBN7.2	X	18,350,015 - 18,351,271 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	18,349,774 - 18,351,516 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	15,752,307 - 15,753,562 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	24,371,393 - 24,372,648 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	18,811,379 - 18,812,635 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	19,243,759 - 19,245,015 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	19,243,759 - 19,245,007 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	20,009,490 - 20,010,746 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	38,583,719 - 38,584,975 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	18,623,129 - 18,624,385 (+)	NCBI		Celera
RGSC_v3.1	X	38,637,191 - 38,638,444 (-)	NCBI
Cytogenetic Map	X	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP,ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

actinomycin D (ISO)

all-trans-retinoic acid (ISO)

Aroclor 1254 (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (EXP)

bisphenol A (ISO)

butanal (ISO)

camptothecin (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

clobetasol (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diazinon (EXP)

Dibutyl phosphate (ISO)

dieldrin (EXP)

doxorubicin (ISO)

endosulfan (EXP)

FR900359 (ISO)

genistein (ISO)

gentamycin (EXP)

GSK-J4 (ISO)

indometacin (ISO)

leflunomide (ISO)

methapyrilene (EXP)

N-methyl-4-phenylpyridinium (EXP)

N-nitrosodiethylamine (EXP)

Nutlin-3 (ISO)

paracetamol (EXP)

pentanal (ISO)

potassium chromate (ISO)

propanal (ISO)

rotenone (ISO)

sodium arsenite (ISO)

sodium dodecyl sulfate (ISO)

tetrachloromethane (ISO)

tetraphene (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of transcription by RNA polymerase II (IBA)

neurotrophin TRK receptor signaling pathway (NAS)

Cellular Component

nucleolus (ISO)

nucleus (IBA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
7.	The p75 neurotrophin receptor interacts with multiple MAGE proteins.	Tcherpakov M, etal., J Biol Chem 2002 Dec 20;277(51):49101-4.

Additional References at PubMed

PMID:15489334

Genomics

Comparative Map Data

Mageh1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	21,725,709 - 21,726,965 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	21,718,669 - 21,727,219 (+)	Ensembl				GRCr8
mRatBN7.2	X	18,350,015 - 18,351,271 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	18,349,774 - 18,351,516 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	15,752,307 - 15,753,562 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	24,371,393 - 24,372,648 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	18,811,379 - 18,812,635 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	19,243,759 - 19,245,015 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	19,243,759 - 19,245,007 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	20,009,490 - 20,010,746 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	38,583,719 - 38,584,975 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	18,623,129 - 18,624,385 (+)	NCBI		Celera
RGSC_v3.1	X	38,637,191 - 38,638,444 (-)	NCBI
Cytogenetic Map	X	q12	NCBI

MAGEH1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	55,452,127 - 55,453,566 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	55,452,127 - 55,453,566 (+)	Ensembl			hg38	GRCh38
GRCh37	X	55,478,560 - 55,479,999 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	55,495,263 - 55,496,724 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	55,361,558 - 55,363,019	NCBI
Celera	X	59,313,626 - 59,315,087 (+)	NCBI		Celera
Cytogenetic Map	X	p11.21	NCBI
HuRef	X	52,527,206 - 52,528,667 (+)	NCBI		HuRef
CHM1_1	X	55,468,683 - 55,470,144 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	54,745,295 - 54,746,734 (+)	NCBI		T2T-CHM13v2.0

Mageh1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	151,819,162 - 151,820,559 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	151,819,162 - 151,820,571 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	153,036,166 - 153,037,563 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	153,036,166 - 153,037,575 (-)	Ensembl			mm10	GRCm38
MGSCv37	X	149,470,709 - 149,472,106 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	148,376,882 - 148,378,068 (-)	NCBI		MGSCv36	mm8
Celera	X	136,216,806 - 136,218,203 (+)	NCBI		Celera
Cytogenetic Map	X	F3	NCBI
cM Map	X	68.46	NCBI

Mageh1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955475	2,600,868 - 2,601,566 (+)	NCBI	ChiLan1.0	ChiLan1.0

MAGEH1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	56,882,317 - 56,883,786 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	56,885,937 - 56,887,393 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	47,713,202 - 47,714,658 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	55,900,707 - 55,902,177 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	55,900,986 - 55,901,645 (+)	Ensembl			panPan2	panpan1.1

MAGEH1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	47,025,749 - 47,027,205 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	47,026,020 - 47,026,679 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	38,261,290 - 38,262,742 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha

Mageh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	39,946,480 - 39,947,939 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936819	1,086,929 - 1,087,588 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936819	1,086,655 - 1,088,123 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAGEH1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	48,080,540 - 48,081,958 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	48,080,533 - 48,081,983 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	54,057,688 - 54,059,138 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAGEH1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	51,533,781 - 51,535,253 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	51,534,052 - 51,534,740 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666712	34,363 - 35,835 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mageh1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	18,269,974 - 18,271,445 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Mageh1
2 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	117
Count of miRNA genes:	95
Interacting mature miRNAs:	104
Transcripts:	ENSRNOT00000004238
Prediction methods:	Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70165	Bp64	Blood pressure QTL 64	5.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	4001493	44939387	Rat
731181	Uae27	Urinary albumin excretion QTL 27	2.7	0.0059	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	X	1970440	46970440	Rat
631666	Iddm5	Insulin dependent diabetes mellitus QTL 5			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	8111486	53111486	Rat
634325	Bw13	Body weight QTL 13	0		body mass (VT:0001259)	body weight (CMO:0000012)	X	4001493	24470521	Rat

Markers in Region

RH143247

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	18,350,279 - 18,350,401 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	19,244,024 - 19,244,145	NCBI	Rnor6.0
Rnor_5.0	X	20,009,755 - 20,009,876	UniSTS	Rnor5.0
RGSC_v3.4	X	38,584,589 - 38,584,710	UniSTS	RGSC3.4
Celera	X	18,623,394 - 18,623,515	UniSTS
RH 3.4 Map	X	209.5	UniSTS
Cytogenetic Map	X	q14	UniSTS

MAGEH1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	X	20,010,008 - 20,010,207	NCBI	Rnor5.0
RGSC_v3.4	X	38,584,258 - 38,584,456	UniSTS	RGSC3.4
Cytogenetic Map	X	q14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	86	59	6	350	186	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC087574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004238 ⟹ ENSRNOP00000004238

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	21,718,669 - 21,727,219 (+)	Ensembl
mRatBN7.2 Ensembl	X	18,349,774 - 18,351,516 (+)	Ensembl
Rnor_6.0 Ensembl	X	19,243,759 - 19,245,007 (+)	Ensembl

RefSeq Acc Id:

NM_001013250 ⟹ NP_001013268

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	21,725,709 - 21,726,965 (+)	NCBI
mRatBN7.2	X	18,350,015 - 18,351,271 (+)	NCBI
Rnor_6.0	X	19,243,759 - 19,245,015 (+)	NCBI
Rnor_5.0	X	20,009,490 - 20,010,746 (+)	NCBI
RGSC_v3.4	X	38,583,719 - 38,584,975 (-)	RGD
Celera	X	18,623,129 - 18,624,385 (+)	RGD

Sequence:

show sequence

CCCGGCGTAAGATAGCCACTTTTCTCAGACGCTGCAGAAAGAGTTCTCCAAGTGCTGCAGGTTT
TCATCGCTTTGCTGGAGCCATGCCTCGGGGACGGAAGAGTAGGCGCCGCCGGAACGCAAAGGCA
GCTGAAGAGAATCGCAACAATCGCAAGATCCAGGCCTCAGAGGCTTCTAAGACCCCGATGGCGG
CTTCTGTGACCCCCAGCACACCCGAAGAATACCTGAGCGGCCCGGAGGAAGACACAAGCACCCC
GGAGAAGGCCTCCAGTACCCTAGCAGAAGCCTCGAGCACTGCCCTAGTGCAAAAGCCTGTTACT
CGGAGCAATTTTCAGGGCACCAAGAAAAGTCTCCTAATGTCCATATTAGCCCTCATCTTCATCA
TGGGCAACAGCGCAAAGGAGGCCCTGGTGTGGAAAGTGCTGGGGAAGTTAGGGATGCAGCCTGG
GAGGCAGCACAGCATCTTTGGAGATCCGAAGAAGGTCGTTACAGAAGAGTTTGTACGCAGGGGG
TATCTGATTTATAAGCCAGTGCCCCGCAGCAGTCCAGTGGAGTATGAGTTCTTCTGGGGCCCTC
GAGCACACGTGGAATCCAGCAAGCTGAAAGTCATGCATTTTGTGGCAAGAGTTCGGAACCGATG
CTCCAAAGACTGGCCATGTAACTATGACTGGGATTCAGATGATGATGCAGAGGTTGAGGCTATT
CTCAATTCAGGTGCTAGGGGTTCTTCTGCTCCATAGAGAGATCCTAGGCAGACCCTTTGGAGTG
GAAAAGAGAATCCAAAGTACTCTATGGAGTAGATAGGCAGGGTCCTGAATTCAAAAGGTTGTGG
AGGGTGGGGAGGGCACTGTATTTGGTATTTGTGATCAGTGCTAATTGTTAAACTGCGAAGTAGT
GTTTGCTATAGATATTGTAATCTTGTATTCATTTTGTAACACTGTTGATCAAGAGTGACAATAT
GTTTAAATATGTACTCGAGGAGAAGTTTATGTTATTTTTTTTTTCCTGTCGTTGACATTTGGTA
TTAACAGCTGTGCTAACCTTATTAAATGAAGTCCTTCTGTCATGTTTTGTGATGGATAGAAAGT
GTACCACTGAGAGAGACTGTTCTTTGAAAGTTTGGAATAACAGTACAACGTGAGTGGAGGAAGA
TAACAGATTTGTTCTGTCTTTCTTTGTGTCTGGTGTCTTGTAATGAAACACATTTGTGATATGC
TCACTGCACAAATAGTATAAATAAAAGCATAGTAAACAGAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013268	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH87574	(Get FASTA)	NCBI Sequence Viewer
	EDL86357	(Get FASTA)	NCBI Sequence Viewer
	Q5PPP4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001013268 ⟸ NM_001013250

- UniProtKB:

Q5PPP4 (UniProtKB/Swiss-Prot), A6KL63 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPRGRKSRRRRNAKAAEENRNNRKIQASEASKTPMAASVTPSTPEEYLSGPEEDTSTPEKASST
LAEASSTALVQKPVTRSNFQGTKKSLLMSILALIFIMGNSAKEALVWKVLGKLGMQPGRQHSIF
GDPKKVVTEEFVRRGYLIYKPVPRSSPVEYEFFWGPRAHVESSKLKVMHFVARVRNRCSKDWPC
NYDWDSDDDAEVEAILNSGARGSSAP

hide sequence

Ensembl Acc Id:

ENSRNOP00000004238 ⟸ ENSRNOT00000004238

Protein Domains

MAGE

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5PPP4-F1-model_v2	AlphaFold	Q5PPP4	1-218	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701761

Promoter ID:

EPDNEW_R12285

Type:

initiation region

Name:

Mageh1_1

Description:

MAGE family member H1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	19,243,675 - 19,243,735	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359316	AgrOrtholog
BioCyc Gene	G2FUF-2827	BioCyc
Ensembl Genes	ENSRNOG00000003178	Ensembl
Gene3D-CATH	1.10.10.1210	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7306512	IMAGE-MGC_LOAD
InterPro	MAGE	UniProtKB/Swiss-Prot
	MAGE_WH2	UniProtKB/Swiss-Prot
	MHD_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:367767	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105800	IMAGE-MGC_LOAD
NCBI Gene	367767	ENTREZGENE
PANTHER	MELANOMA-ASSOCIATED ANTIGEN H1	UniProtKB/Swiss-Prot
	PTHR11736	UniProtKB/Swiss-Prot
Pfam	MAGE	UniProtKB/Swiss-Prot
PhenoGen	Mageh1	PhenoGen
PROSITE	MAGE	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000003178	RatGTEx
SMART	MAGE	UniProtKB/Swiss-Prot
UniProt	A0A8L2Q1A9_RAT	UniProtKB/TrEMBL
	A6KL63	ENTREZGENE, UniProtKB/TrEMBL
	MAGH1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-10	Mageh1	MAGE family member H1	Mageh1	melanoma antigen, family H, 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-11-17	Mageh1	melanoma antigen, family H, 1			Symbol and Name status set to approved	1299863	APPROVED
2005-07-29	Mageh1	melanoma antigen, family H, 1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_mutations_overexpression	ectopic expression of Mageh1 in PC-12 cells caused an acceleration of NGF-induced neuronal differentiation, possibly through synergy between Mage-Ngfr signaling and a TrkA signaling pathway	729117

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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