Armcx6 (armadillo repeat containing, X-linked 6) - Rat Genome Database

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Gene: Armcx6 (armadillo repeat containing, X-linked 6) Rattus norvegicus
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Symbol: Armcx6
Name: armadillo repeat containing, X-linked 6
RGD ID: 1359303
Description: Predicted to be located in mitochondrial outer membrane. Predicted to be active in mitochondrion. Orthologous to human ARMCX6 (armadillo repeat containing X-linked 6); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: arm protein lost in epithelial cancers, X chromosome, 3; MGC93796; protein ARMCX6-like; similar to ALEX3 protein
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X102,222,288 - 102,229,871 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX102,222,220 - 102,240,052 (-)EnsemblGRCr8
mRatBN7.2X97,929,032 - 97,932,031 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,929,041 - 97,931,977 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX99,603,240 - 99,605,838 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X103,119,863 - 103,122,454 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,616,386 - 100,618,984 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X105,565,733 - 105,573,387 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,565,747 - 105,568,343 (-)Ensemblrn6Rnor6.0
Rnor_5.0X105,455,031 - 105,462,670 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X122,189,186 - 122,190,506 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX98,968,749 - 98,971,347 (-)NCBICelera
RGSC_v3.1X122,282,811 - 122,285,391 (-)NCBI
Cytogenetic MapXq32NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334  


Genomics

Comparative Map Data
Armcx6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X102,222,288 - 102,229,871 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX102,222,220 - 102,240,052 (-)EnsemblGRCr8
mRatBN7.2X97,929,032 - 97,932,031 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,929,041 - 97,931,977 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX99,603,240 - 99,605,838 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X103,119,863 - 103,122,454 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,616,386 - 100,618,984 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X105,565,733 - 105,573,387 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,565,747 - 105,568,343 (-)Ensemblrn6Rnor6.0
Rnor_5.0X105,455,031 - 105,462,670 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X122,189,186 - 122,190,506 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX98,968,749 - 98,971,347 (-)NCBICelera
RGSC_v3.1X122,282,811 - 122,285,391 (-)NCBI
Cytogenetic MapXq32NCBI
ARMCX6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X101,615,125 - 101,618,000 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX101,615,118 - 101,618,003 (-)Ensemblhg38GRCh38
GRCh37X100,870,115 - 100,872,990 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,756,764 - 100,759,647 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X100,676,254 - 100,679,136NCBI
CeleraX101,390,686 - 101,393,569 (-)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX90,678,639 - 90,680,796 (-)NCBIHuRef
CHM1_1X100,763,964 - 100,766,847 (-)NCBICHM1_1
T2T-CHM13v2.0X100,059,755 - 100,062,630 (-)NCBIT2T-CHM13v2.0
Armcx6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X133,649,204 - 133,657,236 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX133,649,210 - 133,652,166 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X134,748,455 - 134,756,666 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX134,748,461 - 134,751,417 (-)Ensemblmm10GRCm38
MGSCv37X131,282,994 - 131,285,958 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X130,094,819 - 130,097,776 (-)NCBIMGSCv36mm8
CeleraX117,627,850 - 117,633,973 (-)NCBICelera
Cytogenetic MapXE3NCBI
cM MapX56.25NCBI
ARMCX6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X101,212,229 - 101,215,132 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X101,215,832 - 101,218,737 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X90,815,392 - 90,818,297 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X100,944,169 - 100,947,064 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX100,944,769 - 100,945,671 (-)EnsemblpanPan2panpan1.1
ARMCX6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X75,477,955 - 75,480,908 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX75,478,568 - 75,479,470 (-)EnsemblcanFam3CanFam3.1
Armcx6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X62,857,722 - 62,860,652 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936813614,521 - 617,349 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936813614,456 - 617,354 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100520992
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX83,179,753 - 83,182,679 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X83,179,741 - 83,182,711 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X97,041,524 - 97,044,478 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARMCX6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X89,928,811 - 89,931,696 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX89,929,400 - 89,930,302 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606514,862,569 - 14,865,614 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Armcx6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624902966,797 - 969,992 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Armcx6
52 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:287
Count of miRNA genes:166
Interacting mature miRNAs:204
Transcripts:ENSRNOT00000029807
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X80434318125434318Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX92979612117740458Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat

Markers in Region
RH132685  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X97,911,995 - 97,912,193 (+)MAPPERmRatBN7.2
mRatBN7.2X97,929,110 - 97,929,308 (-)MAPPERmRatBN7.2
mRatBN7.2X97,911,995 - 97,912,193 (-)MAPPERmRatBN7.2
mRatBN7.2X97,929,110 - 97,929,308 (+)MAPPERmRatBN7.2
Rnor_6.0X105,548,697 - 105,548,894NCBIRnor6.0
Rnor_6.0X105,565,812 - 105,566,009NCBIRnor6.0
Rnor_5.0X105,455,110 - 105,455,307UniSTSRnor5.0
Rnor_5.0X105,437,995 - 105,438,192UniSTSRnor5.0
RGSC_v3.4X122,209,446 - 122,209,643UniSTSRGSC3.4
RGSC_v3.4X122,190,244 - 122,190,441UniSTSRGSC3.4
CeleraX98,952,273 - 98,952,471UniSTS
CeleraX98,968,816 - 98,969,013UniSTS
Cytogenetic MapXq34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 12 67 158 91 90 59 91 59 6 350 191 11 137 78 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000029807   ⟹   ENSRNOP00000035673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX102,222,220 - 102,228,855 (-)Ensembl
mRatBN7.2 EnsemblX97,929,041 - 97,931,977 (-)Ensembl
Rnor_6.0 EnsemblX105,565,747 - 105,568,343 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000125436   ⟹   ENSRNOP00000107093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX102,223,009 - 102,231,696 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000125660   ⟹   ENSRNOP00000102465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX102,222,974 - 102,227,532 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000126106   ⟹   ENSRNOP00000104377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX102,222,220 - 102,232,117 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000130446   ⟹   ENSRNOP00000110495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX102,223,048 - 102,240,052 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000134739   ⟹   ENSRNOP00000106578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX102,222,901 - 102,229,322 (-)Ensembl
RefSeq Acc Id: NM_001007757   ⟹   NP_001007758
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X102,222,288 - 102,225,236 (-)NCBI
mRatBN7.2X97,929,032 - 97,931,980 (-)NCBI
Rnor_6.0X105,565,745 - 105,568,343 (-)NCBI
Rnor_5.0X105,455,031 - 105,462,670 (-)NCBI
RGSC_v3.4X122,189,186 - 122,190,506 (+)RGD
CeleraX98,968,749 - 98,971,347 (-)RGD
Sequence:
RefSeq Acc Id: NM_001419692   ⟹   NP_001406621
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X102,222,288 - 102,225,236 (-)NCBI
mRatBN7.2X97,929,032 - 97,931,980 (-)NCBI
RefSeq Acc Id: XM_063280151   ⟹   XP_063136221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X102,222,288 - 102,227,230 (-)NCBI
RefSeq Acc Id: XM_063280152   ⟹   XP_063136222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X102,222,288 - 102,229,871 (-)NCBI
RefSeq Acc Id: NP_001007758   ⟸   NM_001007757
- UniProtKB: Q66HF0 (UniProtKB/Swiss-Prot),   A6IVH5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035673   ⟸   ENSRNOT00000029807
RefSeq Acc Id: NP_001406621   ⟸   NM_001419692
- UniProtKB: Q66HF0 (UniProtKB/Swiss-Prot),   A6IVH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136222   ⟸   XM_063280152
- Peptide Label: isoform X1
- UniProtKB: Q66HF0 (UniProtKB/Swiss-Prot),   A6IVH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136221   ⟸   XM_063280151
- Peptide Label: isoform X1
- UniProtKB: Q66HF0 (UniProtKB/Swiss-Prot),   A6IVH5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102465   ⟸   ENSRNOT00000125660
Ensembl Acc Id: ENSRNOP00000104377   ⟸   ENSRNOT00000126106
Ensembl Acc Id: ENSRNOP00000110495   ⟸   ENSRNOT00000130446
Ensembl Acc Id: ENSRNOP00000106578   ⟸   ENSRNOT00000134739
Ensembl Acc Id: ENSRNOP00000107093   ⟸   ENSRNOT00000125436
Protein Domains
Armadillo repeat-containing

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66HF0-F1-model_v2 AlphaFold Q66HF0 1-301 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359303 AgrOrtholog
BioCyc Gene G2FUF-1672 BioCyc
Ensembl Genes ENSRNOG00000037707 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000029807.6 UniProtKB/Swiss-Prot
  ENSRNOT00000134739 ENTREZGENE
IMAGE_CLONE IMAGE:7109901 IMAGE-MGC_LOAD
InterPro ARM-rpt_dom UniProtKB/Swiss-Prot
  Armcx_regulator UniProtKB/Swiss-Prot
KEGG Report rno:363496 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93796 IMAGE-MGC_LOAD
NCBI Gene 363496 ENTREZGENE
PANTHER ARMADILLO REPEAT CONTAINING PROTEIN UniProtKB/Swiss-Prot
  PROTEIN ARMCX6 UniProtKB/Swiss-Prot
Pfam Arm_2 UniProtKB/Swiss-Prot
PhenoGen Armcx6 PhenoGen
RatGTEx ENSRNOG00000037707 RatGTEx
UniProt A0ABK0LI42_RAT UniProtKB/TrEMBL
  A0ABK0LMX6_RAT UniProtKB/TrEMBL
  A6IVH5 ENTREZGENE, UniProtKB/TrEMBL
  ARMX6_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Armcx6  armadillo repeat containing, X-linked 6  LOC100363147  protein ARMCX6-like  Data merged from RGD:2324743 1643240 APPROVED
2010-05-12 LOC100363147  protein ARMCX6-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 Armcx6  armadillo repeat containing, X-linked 6  MGC93796  similar to ALEX3 protein; arm protein lost in epithelial cancers, X chromosome, 3  Symbol and Name updated 1299863 APPROVED
2005-07-29 MGC93796  similar to ALEX3 protein; arm protein lost in epithelial cancers, X chromosome, 3      Symbol and Name status set to provisional 70820 PROVISIONAL