Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RSL1D1 mRNA] | CTD | PMID:31150632 | (-)-demecolcine | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of RSL1D1 mRNA | CTD | PMID:23649840 | (1->4)-beta-D-glucan | multiple interactions | ISO | Rsl1d1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RSL1D1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | ISO | Rsl1d1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of RSL1D1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | increases expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of RSL1D1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of RSL1D1 mRNA | CTD | PMID:17555576 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RSL1D1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RSL1D1 mRNA | CTD | PMID:33387578 | 2-hydroxypropanoic acid | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of RSL1D1 mRNA | CTD | PMID:30851411 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RSL1D1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RSL1D1 mRNA | CTD | PMID:28628672 | acrolein | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of RSL1D1 mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | aflatoxin B1 | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of RSL1D1 mRNA | CTD | PMID:21641981 | aflatoxin B1 | increases methylation | ISO | RSL1D1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of RSL1D1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of RSL1D1 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of RSL1D1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of RSL1D1 mRNA | CTD | PMID:32699268 | amphotericin B | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Amphotericin B analog results in decreased expression of RSL1D1 mRNA | CTD | PMID:28534445 | Aroclor 1254 | decreases expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of RSL1D1 mRNA | CTD | PMID:23650126 | arsenous acid | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of RSL1D1 mRNA | CTD | PMID:15761015 | belinostat | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RSL1D1 mRNA | CTD | PMID:27188386 | benzo[a]pyrene | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of RSL1D1 mRNA | CTD | PMID:20106945 and PMID:21632981 | benzo[a]pyrene | increases methylation | ISO | RSL1D1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of RSL1D1 3' UTR and Benzo(a)pyrene results in increased methylation of RSL1D1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RSL1D1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of RSL1D1 mRNA | CTD | PMID:20504355 | benzo[a]pyrene diol epoxide I | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 and PMID:26238291 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of RSL1D1 mRNA | CTD | PMID:35550907 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RSL1D1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of RSL1D1 protein | CTD | PMID:34186270 and PMID:37567409 | bisphenol A | affects expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of RSL1D1 mRNA | CTD | PMID:30903817 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of RSL1D1 gene | CTD | PMID:28505145 | bisphenol F | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of RSL1D1 protein | CTD | PMID:34186270 | bleomycin A5 | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | bleomycetin results in increased expression of RSL1D1 mRNA | CTD | PMID:21040473 | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of RSL1D1 promoter | CTD | PMID:22457795 | cadmium dichloride | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of RSL1D1 mRNA | CTD | PMID:25596134 | caffeine | increases phosphorylation | ISO | RSL1D1 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of RSL1D1 protein | CTD | PMID:35688186 | carbon nanotube | increases expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of RSL1D1 mRNA | CTD | PMID:25554681 | chloroacetaldehyde | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | chloroacetaldehyde results in decreased expression of RSL1D1 mRNA | CTD | PMID:25596134 | chromium(6+) | affects expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of RSL1D1 mRNA | CTD | PMID:28472532 | cidofovir anhydrous | affects expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Cidofovir affects the expression of RSL1D1 mRNA | CTD | PMID:25596134 | cisplatin | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of RSL1D1 mRNA | CTD | PMID:25596134 | clofibrate | multiple interactions | ISO | Rsl1d1 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of RSL1D1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of RSL1D1 mRNA] | CTD | PMID:17585979 | copper(II) sulfate | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of RSL1D1 mRNA | CTD | PMID:19549813 | coumarin | affects phosphorylation | ISO | RSL1D1 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of RSL1D1 protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of RSL1D1 mRNA | CTD | PMID:20106945 more ... | deoxynivalenol | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | deoxynivalenol results in increased expression of RSL1D1 mRNA | CTD | PMID:24247028 | dexamethasone | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RSL1D1 mRNA | CTD | PMID:28628672 | diarsenic trioxide | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of RSL1D1 mRNA | CTD | PMID:15761015 | dioxygen | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Oxygen deficiency results in increased expression of RSL1D1 mRNA | CTD | PMID:25596134 | dioxygen | multiple interactions | ISO | Rsl1d1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of RSL1D1 mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RSL1D1 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of RSL1D1 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RSL1D1 protein | CTD | PMID:23301498 | folic acid | multiple interactions | ISO | Rsl1d1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of RSL1D1 mRNA | CTD | PMID:22206623 | formaldehyde | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of RSL1D1 mRNA | CTD | PMID:23649840 | FR900359 | affects phosphorylation | ISO | RSL1D1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of RSL1D1 protein | CTD | PMID:37730182 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of RSL1D1 mRNA | CTD | PMID:26194646 | hypochlorous acid | increases expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Hypochlorous Acid results in increased expression of RSL1D1 mRNA | CTD | PMID:19376150 | ibuprofen | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Ibuprofen results in increased expression of RSL1D1 mRNA | CTD | PMID:25596134 | indometacin | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RSL1D1 mRNA | CTD | PMID:28628672 | inulin | multiple interactions | ISO | Rsl1d1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of RSL1D1 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of RSL1D1 protein | CTD | PMID:32959892 | metformin | increases expression | EXP | | 6480464 | Metformin results in increased expression of RSL1D1 mRNA | CTD | PMID:25596134 | methyl methanesulfonate | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of RSL1D1 mRNA | CTD | PMID:23649840 | N-methyl-4-phenylpyridinium | increases expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of RSL1D1 protein | CTD | PMID:26558463 | ozone | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of RSL1D1 mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | paracetamol | multiple interactions | ISO | Rsl1d1 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of RSL1D1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of RSL1D1 mRNA] | CTD | PMID:17585979 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of RSL1D1 mRNA | CTD | PMID:33387578 | paracetamol | affects expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of RSL1D1 mRNA | CTD | PMID:17562736 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Rsl1d1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RSL1D1 mRNA more ... | CTD | PMID:36331819 | phenobarbital | affects expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of RSL1D1 mRNA | CTD | PMID:19159669 | potassium chromate | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of RSL1D1 mRNA | CTD | PMID:22714537 | quercetin | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Quercetin results in increased expression of RSL1D1 mRNA | CTD | PMID:21632981 | quinolin-8-ol | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Oxyquinoline results in increased expression of RSL1D1 mRNA | CTD | PMID:21632981 | rac-lactic acid | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of RSL1D1 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | silver atom | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Silver results in increased expression of RSL1D1 mRNA | CTD | PMID:26014281 | silver(0) | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Silver results in increased expression of RSL1D1 mRNA | CTD | PMID:26014281 | tamoxifen | affects expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of RSL1D1 mRNA | CTD | PMID:17555576 | tert-butyl hydroperoxide | increases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of RSL1D1 mRNA | CTD | PMID:29432895 | testosterone enanthate | affects expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of RSL1D1 mRNA | CTD | PMID:17440010 | tetrachloromethane | increases expression | ISO | Rsl1d1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of RSL1D1 mRNA | CTD | PMID:27339419 and PMID:31919559 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of RSL1D1 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RSL1D1 mRNA] | CTD | PMID:31150632 | thapsigargin | affects expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Thapsigargin affects the expression of RSL1D1 mRNA | CTD | PMID:24247028 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of RSL1D1 mRNA | CTD | PMID:34492290 | Tributyltin oxide | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | bis(tri-n-butyltin)oxide results in decreased expression of RSL1D1 mRNA | CTD | PMID:24247028 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of RSL1D1 mRNA | CTD | PMID:33387578 | valproic acid | decreases expression | ISO | RSL1D1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of RSL1D1 mRNA | CTD | PMID:19101580 and PMID:23179753 | zinc atom | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of RSL1D1 mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | ISO | RSL1D1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of RSL1D1 mRNA | CTD | PMID:18593933 | |