Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in decreased expression of ZFP219 mRNA | CTD | PMID:27840820 | 1,2-dimethylhydrazine | increases expression | ISO | Zfp219 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of ZFP219 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | Zfp219 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZFP219 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of ZNF219 mRNA | CTD | PMID:30165855 | 17beta-estradiol | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ZNF219 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Zfp219 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZFP219 mRNA | CTD | PMID:21570461 more ... | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ZFP219 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Zfp219 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZFP219 mRNA | CTD | PMID:17942748 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of ZFP219 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of ZFP219 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | increases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of ZNF219 mRNA | CTD | PMID:30851411 | 3,3',4,4',5-pentachlorobiphenyl | affects expression | ISO | Zfp219 (Mus musculus) | 6480464 | 3 more ... | CTD | PMID:23994337 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Zfp219 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of ZFP219 exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Zfp219 (Mus musculus) | 6480464 | bisphenol S affects the methylation of ZFP219 gene | CTD | PMID:31683443 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | ZNF219 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of ZNF219 gene | CTD | PMID:31601247 | acrolein | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ZNF219 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ZNF219 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of ZNF219 mRNA | CTD | PMID:22100608 | aflatoxin B1 | decreases methylation | ISO | ZNF219 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ZNF219 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ZNF219 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ZNF219 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ZNF219 mRNA | CTD | PMID:32699268 | antirheumatic drug | increases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of ZNF219 mRNA | CTD | PMID:24449571 | arsenite(3-) | increases methylation | ISO | ZNF219 (Homo sapiens) | 6480464 | arsenite results in increased methylation of ZNF219 promoter | CTD | PMID:23974009 | atrazine | increases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Atrazine results in increased expression of ZNF219 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | decreases expression | ISO | Zfp219 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ZFP219 mRNA | CTD | PMID:27195522 | benzo[a]pyrene | increases methylation | ISO | ZNF219 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ZNF219 promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | ZNF219 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ZNF219 5' UTR | CTD | PMID:27901495 | beta-naphthoflavone | affects expression | ISO | Zfp219 (Mus musculus) | 6480464 | beta-Naphthoflavone affects the expression of ZFP219 mRNA | CTD | PMID:23994337 | bisphenol A | decreases expression | ISO | Zfp219 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ZFP219 mRNA | CTD | PMID:23798566 | bisphenol A | increases expression | ISO | Zfp219 (Mus musculus) | 6480464 | bisphenol A results in increased expression of ZFP219 mRNA | CTD | PMID:33221593 | bisphenol A | decreases methylation | ISO | ZNF219 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of ZNF219 gene | CTD | PMID:31601247 | bisphenol A | affects methylation | ISO | Zfp219 (Mus musculus) | 6480464 | bisphenol A affects the methylation of ZFP219 promoter | CTD | PMID:27334623 | bisphenol A | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ZNF219 mRNA | CTD | PMID:22576693 | bisphenol A | increases methylation | ISO | ZNF219 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of ZNF219 gene | CTD | PMID:22576693 | butanal | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of ZNF219 mRNA | CTD | PMID:26079696 | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of ZFP219 mRNA | CTD | PMID:19167457 | cadmium atom | multiple interactions | ISO | Zfp219 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZFP219 mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | Zfp219 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZFP219 mRNA | CTD | PMID:37325564 | caffeine | decreases phosphorylation | ISO | ZNF219 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of ZNF219 protein | CTD | PMID:35688186 | CGP 52608 | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ZNF219 gene] | CTD | PMID:28238834 | clothianidin | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | clothianidin results in decreased expression of ZNF219 mRNA | CTD | PMID:29044138 | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of ZFP219 mRNA | CTD | PMID:30556269 | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of ZFP219 mRNA | CTD | PMID:30556269 | copper(II) sulfate | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ZNF219 mRNA | CTD | PMID:19549813 | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of ZFP219 mRNA | CTD | PMID:26577399 | cyclophosphamide | increases expression | EXP | | 6480464 | Cyclophosphamide results in increased expression of ZFP219 mRNA | CTD | PMID:27281708 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of ZFP219 mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ZNF219 mRNA | CTD | PMID:29803840 | elemental selenium | increases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Selenium results in increased expression of ZNF219 mRNA | CTD | PMID:19244175 | elemental selenium | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of ZNF219 mRNA | CTD | PMID:19244175 | folic acid | affects expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Folic Acid affects the expression of ZNF219 mRNA | CTD | PMID:17320366 | FR900359 | increases phosphorylation | ISO | ZNF219 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of ZNF219 protein | CTD | PMID:37730182 | hexamethylene diisocyanate | increases methylation | ISO | ZNF219 (Homo sapiens) | 6480464 | 1 and 6-hexamethylene diisocyanate results in increased methylation of ZNF219 promoter | CTD | PMID:25445006 | inulin | multiple interactions | ISO | Zfp219 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ZFP219 mRNA | CTD | PMID:36331819 | lead(0) | affects expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Lead affects the expression of ZNF219 mRNA | CTD | PMID:28903495 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of ZFP219 mRNA | CTD | PMID:28801915 | ozone | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ZNF219 mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | ISO | Zfp219 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of ZFP219 mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ZNF219 mRNA | CTD | PMID:29067470 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Zfp219 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ZFP219 mRNA | CTD | PMID:36331819 | propiconazole | decreases expression | ISO | Zfp219 (Mus musculus) | 6480464 | propiconazole results in decreased expression of ZFP219 mRNA | CTD | PMID:21278054 | rac-lactic acid | increases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of ZNF219 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | selenium atom | increases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Selenium results in increased expression of ZNF219 mRNA | CTD | PMID:19244175 | selenium atom | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of ZNF219 mRNA | CTD | PMID:19244175 | tamoxifen | increases expression | ISO | Zfp219 (Mus musculus) | 6480464 | Tamoxifen results in increased expression of ZFP219 mRNA | CTD | PMID:17555576 | testosterone | increases expression | ISO | Zfp219 (Mus musculus) | 6480464 | Testosterone deficiency results in increased expression of ZFP219 mRNA | CTD | PMID:33848595 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of ZFP219 gene | CTD | PMID:27618143 | trichostatin A | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of ZNF219 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF219 mRNA | CTD | PMID:27188386 | urethane | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Urethane results in decreased expression of ZNF219 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | Zfp219 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of ZFP219 mRNA | CTD | PMID:21427059 | valproic acid | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF219 mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ZNF219 mRNA | CTD | PMID:23179753 more ... | valproic acid | increases methylation | ISO | ZNF219 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ZNF219 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ZNF219 mRNA | CTD | PMID:25979313 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of ZFP219 mRNA | CTD | PMID:23034163 | vitamin E | multiple interactions | ISO | ZNF219 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of ZNF219 mRNA | CTD | PMID:19244175 | vitamin E | increases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of ZNF219 mRNA | CTD | PMID:19244175 | vorinostat | decreases expression | ISO | ZNF219 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of ZNF219 mRNA | CTD | PMID:27188386 | |