Xkrx (XK related, X-linked) - Rat Genome Database

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Gene: Xkrx (XK related, X-linked) Rattus norvegicus
Analyze
Symbol: Xkrx
Name: XK related, X-linked
RGD ID: 1359223
Description: Predicted to be located in plasma membrane. Orthologous to human XKRX (XK related X-linked); INTERACTS WITH 3,7-dihydropurine-6-thione; acrylamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: X Kell blood group precursor related X linked; x Kell blood group-related, X-linked; XK, Kell blood group complex subunit-related, X-linked; XK-related protein 2; XRG2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X101,634,438 - 101,733,814 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX101,635,283 - 101,646,461 (-)EnsemblGRCr8
mRatBN7.2X97,341,158 - 97,353,175 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,341,152 - 97,354,759 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX99,016,147 - 99,027,319 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X102,525,920 - 102,537,113 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,029,303 - 100,040,485 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X104,973,083 - 104,984,261 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX104,968,582 - 104,984,341 (-)Ensemblrn6Rnor6.0
Rnor_5.0X104,802,523 - 104,813,697 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X121,609,916 - 121,621,094 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX98,385,348 - 98,396,526 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Xkrx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X101,634,438 - 101,733,814 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX101,635,283 - 101,646,461 (-)EnsemblGRCr8
mRatBN7.2X97,341,158 - 97,353,175 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,341,152 - 97,354,759 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX99,016,147 - 99,027,319 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X102,525,920 - 102,537,113 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,029,303 - 100,040,485 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X104,973,083 - 104,984,261 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX104,968,582 - 104,984,341 (-)Ensemblrn6Rnor6.0
Rnor_5.0X104,802,523 - 104,813,697 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X121,609,916 - 121,621,094 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX98,385,348 - 98,396,526 (-)NCBICelera
Cytogenetic MapXq32NCBI
XKRX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X100,886,916 - 100,959,343 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX100,913,445 - 100,929,433 (-)Ensemblhg38GRCh38
GRCh37X100,168,434 - 100,183,906 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,055,092 - 100,070,554 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X99,974,580 - 99,990,043NCBI
CeleraX100,687,232 - 100,702,698 (-)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX89,966,788 - 89,982,220 (-)NCBIHuRef
CHM1_1X100,061,373 - 100,076,840 (-)NCBICHM1_1
T2T-CHM13v2.0X99,329,581 - 99,402,028 (-)NCBIT2T-CHM13v2.0
Xkrx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X133,049,786 - 133,086,747 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX133,049,792 - 133,062,825 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X134,149,037 - 134,185,497 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX134,149,043 - 134,162,076 (-)Ensemblmm10GRCm38
MGSCv37X130,683,584 - 130,696,467 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X129,495,395 - 129,508,278 (-)NCBIMGSCv36mm8
CeleraX117,025,592 - 117,038,445 (-)NCBICelera
Cytogenetic MapXE3NCBI
cM MapX55.85NCBI
Xkrx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555037,037,200 - 7,066,070 (-)Ensembl
ChiLan1.0NW_0049555037,037,200 - 7,066,070 (-)NCBIChiLan1.0ChiLan1.0
XKRX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X100,511,091 - 100,528,864 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X100,516,499 - 100,532,451 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X90,116,066 - 90,132,075 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X100,254,293 - 100,270,253 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX100,254,293 - 100,270,253 (-)EnsemblpanPan2panpan1.1
XKRX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X74,854,947 - 74,872,918 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX74,859,659 - 74,872,259 (-)EnsemblcanFam3CanFam3.1
ROS_Cfam_1.0X76,268,064 - 76,285,331 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX76,272,753 - 76,285,301 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X73,836,381 - 73,853,642 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X75,496,928 - 75,514,183 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X75,259,829 - 75,275,887 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Xkrx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X63,439,696 - 63,453,012 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493681322,094 - 34,529 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493681322,094 - 34,529 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XKRX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX82,610,758 - 82,630,310 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X82,614,592 - 82,630,188 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X90,542,958 - 90,557,933 (-)NCBISscrofa10.2Sscrofa10.2susScr3
XKRX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X89,249,577 - 89,354,560 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX89,250,482 - 89,264,591 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606514,173,444 - 14,189,963 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xkrx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249021,678,615 - 1,696,820 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249021,677,588 - 1,694,988 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Xkrx
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X86,480,249 - 86,492,062 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Xkrx
479 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:195
Count of miRNA genes:150
Interacting mature miRNAs:165
Transcripts:ENSRNOT00000039988
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X80434318125434318Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX92979612117740458Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 8 54 156 85 84 53 92 53 6 325 177 10 133 74 83 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000077996   ⟹   ENSRNOP00000070278
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX104,968,582 - 104,984,341 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109191   ⟹   ENSRNOP00000096396
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX97,341,152 - 97,354,127 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114392   ⟹   ENSRNOP00000090437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX97,341,159 - 97,354,759 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000137513   ⟹   ENSRNOP00000105574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX101,635,283 - 101,646,461 (-)Ensembl
RefSeq Acc Id: NM_001012230   ⟹   NP_001012230
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,635,283 - 101,646,461 (-)NCBI
mRatBN7.2X97,342,003 - 97,353,175 (-)NCBI
Rnor_6.0X104,973,083 - 104,984,261 (-)NCBI
Rnor_5.0X104,802,523 - 104,813,697 (-)NCBI
RGSC_v3.4X121,609,916 - 121,621,094 (-)RGD
CeleraX98,385,348 - 98,396,526 (-)RGD
Sequence:
RefSeq Acc Id: XM_039099958   ⟹   XP_038955886
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,634,438 - 101,640,112 (-)NCBI
mRatBN7.2X97,341,158 - 97,346,634 (-)NCBI
RefSeq Acc Id: XM_063280187   ⟹   XP_063136257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,634,438 - 101,699,901 (-)NCBI
RefSeq Acc Id: XM_063280188   ⟹   XP_063136258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,634,438 - 101,733,812 (-)NCBI
RefSeq Acc Id: XM_063280189   ⟹   XP_063136259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,634,438 - 101,699,898 (-)NCBI
RefSeq Acc Id: XM_063280190   ⟹   XP_063136260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,634,438 - 101,733,814 (-)NCBI
RefSeq Acc Id: XM_063280191   ⟹   XP_063136261
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,634,438 - 101,699,898 (-)NCBI
RefSeq Acc Id: XM_063280192   ⟹   XP_063136262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,634,438 - 101,733,809 (-)NCBI
RefSeq Acc Id: XM_063280193   ⟹   XP_063136263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,634,438 - 101,733,814 (-)NCBI
RefSeq Acc Id: XM_063280194   ⟹   XP_063136264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,634,438 - 101,676,427 (-)NCBI
RefSeq Acc Id: XM_063280195   ⟹   XP_063136265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,634,438 - 101,733,775 (-)NCBI
RefSeq Acc Id: NP_001012230   ⟸   NM_001012230
- UniProtKB: Q5GH60 (UniProtKB/Swiss-Prot),   A6IVE5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070278   ⟸   ENSRNOT00000077996
RefSeq Acc Id: XP_038955886   ⟸   XM_039099958
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000096396   ⟸   ENSRNOT00000109191
Ensembl Acc Id: ENSRNOP00000090437   ⟸   ENSRNOT00000114392
RefSeq Acc Id: XP_063136263   ⟸   XM_063280193
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136260   ⟸   XM_063280190
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136258   ⟸   XM_063280188
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136262   ⟸   XM_063280192
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136265   ⟸   XM_063280195
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136257   ⟸   XM_063280187
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136259   ⟸   XM_063280189
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136261   ⟸   XM_063280191
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063136264   ⟸   XM_063280194
- Peptide Label: isoform X1
- UniProtKB: Q5GH60 (UniProtKB/Swiss-Prot),   A6IVE5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105574   ⟸   ENSRNOT00000137513

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5GH60-F1-model_v2 AlphaFold Q5GH60 1-448 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359223 AgrOrtholog
BioCyc Gene G2FUF-1693 BioCyc
Ensembl Genes ENSRNOG00000054136 Ensembl
  ENSRNOG00000067363 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000089589 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000114392.1 UniProtKB/Swiss-Prot
  ENSRNOT00000137513 ENTREZGENE
InterPro XK-rel UniProtKB/Swiss-Prot
  XK-related_adapter UniProtKB/Swiss-Prot
KEGG Report rno:497101 UniProtKB/Swiss-Prot
NCBI Gene 497101 ENTREZGENE
PANTHER MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER UniProtKB/Swiss-Prot
  XK-RELATED PROTEIN 2 UniProtKB/Swiss-Prot
Pfam XK-related UniProtKB/Swiss-Prot
PhenoGen Xkrx PhenoGen
RatGTEx ENSRNOG00000054136 RatGTEx
  ENSRNOG00000067363 RatGTEx
  ENSRNOG00000089589 RatGTEx
UniProt A6IVE5 ENTREZGENE, UniProtKB/TrEMBL
  Q5GH60 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Xkrx  XK related, X-linked  Xkrx  XK, Kell blood group complex subunit-related, X-linked  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Xkrx  XK, Kell blood group complex subunit-related, X-linked  Xkrx  X Kell blood group precursor related X linked  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Xkrx  X Kell blood group precursor related X linked  XRG2  XK-related protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 XRG2  XK-related protein 2      Symbol and Name status set to provisional 70820 PROVISIONAL