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Gene: Utp25 (UTP25 small subunit processome component) Rattus norvegicus

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Symbol:

Utp25

Name:

UTP25 small subunit processome component

RGD ID:

1359148

Description:

Predicted to enable U3 snoRNA binding activity and rRNA binding activity. Predicted to be involved in several processes, including maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); protein destabilization; and protein localization to nucleolus. Predicted to be located in nucleus. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human UTP25 (UTP25 small subunit processome component); INTERACTS WITH (+)-schisandrin B; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Def; Diexf; digestive organ expansion factor homolog; digestive organ expansion factor homolog (zebrafish); LOC305076; novel putative protein similar to YIL091C yeast hypothetical 84 kD protein from SGA1-KTR7; similar to hypothetical protein MGC29875; U3 small nucleolar RNA-associated protein 25 homolog; UTP25, small subunit processor component

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UTP25 (UTP25 small subunit processome component)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Utp25 (UTP25 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Utp25 (UTP25 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UTP25 (UTP25 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	UTP25 (UTP25 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Utp25 (UTP25 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UTP25 (UTP25 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	UTP25 (UTP25 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Utp25 (UTP25 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Utp25 (UTP25 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	UTP25 (UTP25 small subunit processome component)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Utp25 (UTP25 small subunit processome component)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y41C4A.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG3735	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	UTP25	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	utp25	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	utp25	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	107,159,092 - 107,180,361 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	107,149,183 - 107,180,361 (-)	Ensembl				GRCr8
mRatBN7.2	13	104,630,390 - 104,651,681 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	104,630,391 - 104,651,662 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	107,148,008 - 107,169,277 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	108,531,858 - 108,553,127 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	105,749,825 - 105,771,095 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	111,828,052 - 111,849,654 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	111,828,043 - 111,849,653 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	116,382,860 - 116,404,451 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	108,945,112 - 108,966,381 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	104,060,438 - 104,081,707 (-)	NCBI		Celera
RGSC_v3.1	13	109,134,216 - 109,155,439 (-)	NCBI
Cytogenetic Map	13	q27	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hirschsprung's disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

DDE (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

lead(0) (ISO)

leflunomide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

melphalan (ISO)

paracetamol (EXP,ISO)

perfluorononanoic acid (ISO)

phenylmercury acetate (ISO)

potassium chromate (ISO)

SB 431542 (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (EXP,ISO)

triptonide (ISO)

troglitazone (ISO)

urethane (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

embryonic organ development (IEA,ISO,ISS)

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IBA)

positive regulation of embryonic development (ISO,ISS)

protein catabolic process (IEA,ISO,ISS)

protein destabilization (IEA,ISO,ISS)

protein localization to nucleolus (IEA,ISO,ISS)

rRNA processing (IEA)

Cellular Component

nucleolus (IBA,IEA,ISO,ISS)

small-subunit processome (IBA)

Molecular Function

protein binding (ISO)

rRNA binding (IBA)

U3 snoRNA binding (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:22658674	PMID:23357851	PMID:29262616

Genomics

Comparative Map Data

Utp25
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	107,159,092 - 107,180,361 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	107,149,183 - 107,180,361 (-)	Ensembl				GRCr8
mRatBN7.2	13	104,630,390 - 104,651,681 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	104,630,391 - 104,651,662 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	107,148,008 - 107,169,277 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	108,531,858 - 108,553,127 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	105,749,825 - 105,771,095 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	111,828,052 - 111,849,654 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	111,828,043 - 111,849,653 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	116,382,860 - 116,404,451 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	108,945,112 - 108,966,381 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	104,060,438 - 104,081,707 (-)	NCBI		Celera
RGSC_v3.1	13	109,134,216 - 109,155,439 (-)	NCBI
Cytogenetic Map	13	q27	NCBI

UTP25
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	209,827,972 - 209,857,565 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	209,827,972 - 209,857,565 (+)	Ensembl			hg38	GRCh38
GRCh37	1	210,001,317 - 210,030,910 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	208,067,956 - 208,097,531 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	183,232,203 - 183,261,798 (+)	NCBI		Celera
Cytogenetic Map	1	q32.2	NCBI
HuRef	1	180,676,427 - 180,706,025 (+)	NCBI		HuRef
CHM1_1	1	211,273,584 - 211,303,174 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	209,074,743 - 209,104,338 (+)	NCBI		T2T-CHM13v2.0

Utp25
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	192,786,707 - 192,812,603 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	192,773,412 - 192,812,580 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	193,104,399 - 193,130,283 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	193,091,104 - 193,130,272 (-)	Ensembl			mm10	GRCm38
MGSCv37	1	194,930,597 - 194,956,445 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	194,805,127 - 194,830,975 (-)	NCBI		MGSCv36	mm8
Celera	1	199,979,507 - 200,005,362 (-)	NCBI		Celera
Cytogenetic Map	1	H6	NCBI
cM Map	1	97.56	NCBI

Utp25
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955489	2,339,745 - 2,387,103 (-)	Ensembl
ChiLan1.0	NW_004955489	2,362,290 - 2,387,162 (-)	NCBI	ChiLan1.0	ChiLan1.0

UTP25
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	39,548,962 - 39,574,522 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	39,515,382 - 39,540,687 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	185,403,715 - 185,433,830 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	190,268,857 - 190,292,729 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	190,268,857 - 190,292,980 (+)	Ensembl			panPan2	panpan1.1

UTP25
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	8,477,026 - 8,512,713 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	8,488,350 - 8,512,705 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	8,065,263 - 8,090,352 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	8,188,707 - 8,214,441 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	8,188,839 - 8,215,357 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	8,118,398 - 8,143,450 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	8,215,411 - 8,240,320 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	8,242,865 - 8,266,776 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Utp25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	66,003,992 - 66,028,584 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936557	3,223,470 - 3,268,888 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936557	3,244,274 - 3,268,853 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UTP25
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	133,105,063 - 133,141,217 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	133,115,177 - 133,141,258 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	146,382,511 - 146,400,265 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UTP25
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	19,601,165 - 19,625,274 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	19,600,266 - 19,625,229 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	20,200,305 - 20,224,419 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Utp25
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	2,145,963 - 2,166,885 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624807	2,069,501 - 2,166,859 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Utp25
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	71,092,172 - 71,113,835 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	183
Count of miRNA genes:	136
Interacting mature miRNAs:	145
Transcripts:	ENSRNOT00000006395
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
7387280	Uae43	Urinary albumin excretion QTL 43	5.69	0.4174	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	68983334	109350286	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
8655951	Rf63	Renal function QTL 63	12.2		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	13	71610804	109350286	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	83286150	109350286	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Markers in Region

BF392838

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	104,640,515 - 104,641,120 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	111,838,486 - 111,839,090	NCBI	Rnor6.0
Rnor_5.0	13	116,393,294 - 116,393,898	UniSTS	Rnor5.0
RGSC_v3.4	13	108,955,236 - 108,955,840	UniSTS	RGSC3.4
Celera	13	104,070,562 - 104,071,166	UniSTS
RH 3.4 Map	13	757.6	UniSTS
Cytogenetic Map	13	q27	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272402	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC087114	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB569988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217506	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006395 ⟹ ENSRNOP00000006395

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	107,159,093 - 107,180,361 (-)	Ensembl
mRatBN7.2 Ensembl	13	104,630,391 - 104,651,662 (-)	Ensembl
Rnor_6.0 Ensembl	13	111,828,043 - 111,849,653 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000129659 ⟹ ENSRNOP00000104248

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	107,149,183 - 107,180,361 (-)	Ensembl

RefSeq Acc Id:

NM_001013986 ⟹ NP_001014008

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	107,159,092 - 107,180,361 (-)	NCBI
mRatBN7.2	13	104,630,390 - 104,651,662 (-)	NCBI
Rnor_6.0	13	111,828,360 - 111,849,631 (-)	NCBI
Rnor_5.0	13	116,382,860 - 116,404,451 (-)	NCBI
RGSC_v3.4	13	108,945,112 - 108,966,381 (-)	RGD
Celera	13	104,060,438 - 104,081,707 (-)	RGD

Sequence:

show sequence

CCGGCGTACCCACGTGCGACAACTTCCCACTGGAAACCTTGGGTTTGGTTGTTGTGTTTTTTAT
GTTGTGGTGGGAAGCTTGACGTTTCCGCTATGGGCAAACGCCGGAGTCGTGGCCGCAGCCAGCT
GCTCAGCACAATGACCAAGAAGCAGAAGAAGCACCTCCGCGACTTCGGCGAGGAGCACCCCTTC
TACGACAGGGTTTCCAAGAAGGAAGTCAAGCCGCAAATTTGTCAGCTGTCAGAGAGCTCAGATT
CTTCACATTCTGAAAGTGAATCAGAGAGTGAACAAGAGCATGTTTCGGGGTACCACAGACTGCT
TGCTACATTAAAGAACATTTCTGAGGAGGAGGAGGAAGAGGAGGAAGAAGAAGAGGAGGAGGAG
GAAGACAAAGAGGAGGTGGATGACAGTGCTGTAGGTGATTCGGAAATGAATGGTGAAGATGGCG
GTGAGGATGTCCGTGTGGAAGAAACTGCAGAGTCCTCTGAGACACAGGACCATATGTCTCTAGC
TGACAACTCAAAAGGAAAAGATGGTGAAGAGCCACCTGGTGTATCACAGAAATCTTCAGAGGAG
TTCACAGATGTGAAACACGAGTCACTGTTCAGCCTGGAAACCAATTTTCTAGAAGAGGAGAGTG
GGGGCAGTTATTCCCAGAGAACATCCCAAGATCCATTTCAACATCACATCAACAAAGAACTGCA
AGAAAAGGAAATTCAAGCCGCTGCCTCAAGCCCTGCAGCTACCCAGCAACTGAAATGGCCAGTC
CTGGGACATCTTGTCTTTTCATCAAAGTTCCAGAAGATGGAAACATTTAAACCTCCAAAGGATA
TTGACCTAAAGTCACTTCATCTTCAGAAGCCCCTAGAATCCACCTGGGCAAAAACCAACAGCCA
ATTTCTATCTGGTCCTGGTCCTCAAAAATCAAGTAGCTGCTTTACCCCACTCCAGAAAGAGCTG
TTCTTGATTATGAATTCTTACCGGGACCTGTTCTACCCTGAGAGGACTGCCCTGAAGAATGGAG
AAGAAGTCCGCCATGTGTACTGCCTGCATGCCATAAACCACGTCCTCAAAGCCAATGCTCAAGT
GCTGGCTAACAACAGCAGGCGCCGGACCCAGAAACTCGGGGTGGGTGACGATGATGACTTCAGG
GACCAGGGGCTCACCAGGCCCAAGGTACTTATAGTGGTGCCTTTCCGGGAAGCTGCCCTTCGGG
TGGTCCAGCTCTTCATCAGCCTCCTTGAGGGGGACAGCAAGAAGAAAATCATTGTAAGCAATAA
AAAGAGGTTTCAGGGGGAATATGGATCTGACCCTGAGGAGAGACCTCCCAACCTGAAGAGGCCT
GAGGATTATGAAGCTGTGTTCGTGGGCAATATTGATGACCACTTCAGGATTGGAGTGGCGATAC
TTCAGAGGAGCATCCGTCTCTACGCCCCGTTTTACTCCTCTGACATCCTCATTGCCTCCCCCCT
GGGCTTGAGGACCATCATTGGTGGTGAAGGAGAGAAGAAGAGAGATTTTGACTTCCTGTCTTCT
ATTGAGCTTCTGATCATTGACCAGGCTGACATTTACCTGATGCAGAACTGGGAACATGTCTTGC
ATTTGATGAACCACATGAACCTGTTACCCTTGGACTCACATGGGGTGAACTTCTCTAGAGTACG
CATGTGGAGCCTCAATAACTGGTCCAAGTATTACCGTCAGACTCTGCTCTTTGGTGCCCTGCAG
GATGCCCAGATCAACTCTGTGTTCAACAAGCACTGTGTCAATGCTCAAGGCCAAGTGGCTGTGA
GGAATGTCCCCATGACGGGTTCCATCAGTCATGTGTTGGTGCAGCTGCCTCACGTCTTCCAGAG
AATGGAAGCACAAGACCTAGCTTCAGTGATCGATGCCAGGTTTCACTTTTTCATAAACAAGATT
CTGCCTCAGTACCGGGATGCTGTCATGTCTCACACCCTCATCTATGTCCCCTCCTACTTTGACT
TTGTTCGTCTCCGAAATTACTTCAAGAAAGAAGAACTGAACTTTACACACATCTGTGAGTATAC
ACAGAGGTCTGGCGTCTCCAGGGCTCGACACTTCTTTCTCCAAGGAGAGAAGCAGTTTCTGCTC
CTCACAGAACGCTTCCATTTCTACAAAAGGTACACAATAAAAGGCATCAGGAACCTCATATTCT
ACGAACTGCCAACATACGCTCACTTCTACAGTGAGGTCTGTAATATGCTGAGAGCCACCAGCAG
AGGAGAGGAGGCCACATGGACGTGCACTGTGCTGTATTCCAAGTATGATGCCCAGAGGCTGGCT
GCTGTGGTTGGTGTGGAGCGGGCAGCACAGATGCTGCAGTCTCCAAAGAGTGTCCACCTCTTCA
TCACTGGAGAAAAATGAGTGTGGAGTGGGACAACTACATTGATGGACCTCATAGACTTGGTCTG
CTCACTGCCCAGGAGCAGGCTCTAGGCAGTCTGCAGTCCTGTGCCCTGGAAAGTGCAGTGTGAC
CCGTGCGGGTAACCATAGCTCTCGGGGCCCAGAGCAGTAAAAGGACTGCCACACACAGAAACCA
AAGCTTGTGCTTGTCACACTTTTTAAGCTGTAACTTCTCAATTATGATTTTAATTTTTTAATTT
AATTATTATTTTATATGCAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_063272402 ⟹ XP_063128472

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	107,159,092 - 107,176,847 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014008	(Get FASTA)	NCBI Sequence Viewer
	XP_063128472	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH87114	(Get FASTA)	NCBI Sequence Viewer
	EDL95025	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006395
	ENSRNOP00000006395.4
GenBank Protein	Q5M9G7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001014008 ⟸ NM_001013986

- UniProtKB:

Q5M9G7 (UniProtKB/Swiss-Prot), A6JH19 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGKRRSRGRSQLLSTMTKKQKKHLRDFGEEHPFYDRVSKKEVKPQICQLSESSDSSHSESESES
EQEHVSGYHRLLATLKNISEEEEEEEEEEEEEEEDKEEVDDSAVGDSEMNGEDGGEDVRVEETA
ESSETQDHMSLADNSKGKDGEEPPGVSQKSSEEFTDVKHESLFSLETNFLEEESGGSYSQRTSQ
DPFQHHINKELQEKEIQAAASSPAATQQLKWPVLGHLVFSSKFQKMETFKPPKDIDLKSLHLQK
PLESTWAKTNSQFLSGPGPQKSSSCFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLH
AINHVLKANAQVLANNSRRRTQKLGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLE
GDSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAP
FYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLP
LDSHGVNFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCVNAQGQVAVRNVPMTGSIS
HVLVQLPHVFQRMEAQDLASVIDARFHFFINKILPQYRDAVMSHTLIYVPSYFDFVRLRNYFKK
EELNFTHICEYTQRSGVSRARHFFLQGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYAHFY
SEVCNMLRATSRGEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSPKSVHLFITGEK

hide sequence

Ensembl Acc Id:

ENSRNOP00000006395 ⟸ ENSRNOT00000006395

RefSeq Acc Id:	XP_063128472 ⟸ XM_063272402
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000104248 ⟸ ENSRNOT00000129659

Protein Domains

UTP25 C-terminal UTP25 NTP hydrolase-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5M9G7-F1-model_v2	AlphaFold	Q5M9G7	1-763	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699124

Promoter ID:

EPDNEW_R9649

Type:

initiation region

Name:

Diexf_1

Description:

digestive organ expansion factor homolog

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	111,849,610 - 111,849,670	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359148	AgrOrtholog
BioCyc Gene	G2FUF-16797	BioCyc
Ensembl Genes	ENSRNOG00000004789	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000006395	ENTREZGENE
	ENSRNOT00000006395.7	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7193786	IMAGE-MGC_LOAD
InterPro	Digest_organ_expansion_fac-prd	UniProtKB/Swiss-Prot
	P-loop_NTPase	UniProtKB/Swiss-Prot
	UTP25_C	UniProtKB/Swiss-Prot
	UTP25_NTPase-like	UniProtKB/Swiss-Prot
KEGG Report	rno:305076	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94741	IMAGE-MGC_LOAD
NCBI Gene	305076	ENTREZGENE
PANTHER	PTHR12933	UniProtKB/Swiss-Prot
	U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG	UniProtKB/Swiss-Prot
Pfam	UTP25	UniProtKB/Swiss-Prot
	UTP25_NTPase-like	UniProtKB/Swiss-Prot
PhenoGen	Utp25	PhenoGen
RatGTEx	ENSRNOG00000004789	RatGTEx
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
UniProt	A0ABK0LSE1_RAT	UniProtKB/TrEMBL
	A6JH19	ENTREZGENE, UniProtKB/TrEMBL
	DIEXF_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-03-14	Utp25	UTP25 small subunit processome component	Utp25	UTP25, small subunit processor component	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2018-05-07	Utp25	UTP25, small subunit processor component	Diexf	digestive organ expansion factor homolog (zebrafish)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-05-25	Diexf	digestive organ expansion factor homolog (zebrafish)	LOC305076	similar to hypothetical protein MGC29875; novel putative protein similar to YIL091C yeast hypothetical 84 kD protein from SGA1-KTR7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-29	LOC305076	similar to hypothetical protein MGC29875; novel putative protein similar to YIL091C yeast hypothetical 84 kD protein from SGA1-KTR7			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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