Selenot (selenoprotein T) - Rat Genome Database

Name: Selenot
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Advanced Search (OLGA)

Gene: Selenot (selenoprotein T) Rattus norvegicus

Analyze

Symbol:

Selenot

Name:

selenoprotein T

RGD ID:

1359128

Description:

Enables thioredoxin-disulfide reductase (NADPH) activity. Involved in cellular oxidant detoxification; positive regulation of cytosolic calcium ion concentration; and positive regulation of growth hormone secretion. Located in endoplasmic reticulum membrane. Orthologous to human SELENOT (selenoprotein T); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; amitrole.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

LOC365802; Selt; similar to Selenoprotein T; thioredoxin reductase-like enzyme; thioredoxin reductase-like selenoprotein T

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SELENOT (selenoprotein T)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL
Mus musculus (house mouse):	Selenot (selenoprotein T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Selenot (selenoprotein T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SELENOT (selenoprotein T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SELENOT (selenoprotein T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Selenot (selenoprotein T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SELENOT (selenoprotein T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SELENOT (selenoprotein T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Selenot (selenoprotein T)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Selenot (selenoprotein T)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SELENOT (selenoprotein T)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	selt-1.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	SelT	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	selenot1a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	selt-1.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	selenot1b	Alliance	DIOPT (Hieranoid\|OMA\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	selenot	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Related Pseudogenes:

Selenot-ps1

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	144,954,324 - 144,971,375 (+)	NCBI		GRCr8
mRatBN7.2	2	142,804,387 - 142,821,438 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	142,804,405 - 142,821,427 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	149,442,810 - 149,459,866 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	147,549,455 - 147,566,511 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	142,181,889 - 142,198,945 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	148,765,412 - 148,781,080 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	148,765,412 - 148,780,276 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	168,183,454 - 168,198,181 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	147,913,245 - 147,929,296 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	147,863,312 - 147,878,392 (+)	NCBI
Celera	2	137,233,019 - 137,248,625 (+)	NCBI		Celera
Cytogenetic Map	2	q26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

glycogen storage disease XV (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-trichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

6-propyl-2-thiouracil (EXP)

amitrole (EXP)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

bucladesine (EXP)

cadmium dichloride (EXP)

calcium atom (EXP)

calcium(0) (EXP)

copper(II) sulfate (ISO)

coumestrol (ISO)

dicrotophos (ISO)

Diisodecyl phthalate (ISO)

dorsomorphin (ISO)

fipronil (EXP)

folic acid (ISO)

gold atom (ISO)

gold(0) (ISO)

ivermectin (ISO)

lead(0) (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

miconazole (EXP)

N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide (EXP)

nickel dichloride (EXP)

resveratrol (ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

thapsigargin (EXP)

titanium dioxide (ISO)

Tributyltin oxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell redox homeostasis (IBA,IEA,ISO,ISS)

cellular oxidant detoxification (IDA)

glucose homeostasis (ISO,ISS)

insulin secretion involved in cellular response to glucose stimulus (IEA,ISO,ISS)

pancreas development (IEA,ISO,ISS)

positive regulation of cytosolic calcium ion concentration (IMP)

positive regulation of growth hormone secretion (IMP)

response to glucose (ISO,ISS)

Cellular Component

endoplasmic reticulum (IEA,ISO)

endoplasmic reticulum membrane (IBA,IDA)

Molecular Function

thioredoxin-disulfide reductase (NADPH) activity (IBA,IDA)

References

References - curated

#	Reference Title	Reference Citation
1.	Selenoprotein T Exerts an Essential Oxidoreductase Activity That Protects Dopaminergic Neurons in Mouse Models of Parkinson's Disease.	Boukhzar L, etal., Antioxid Redox Signal. 2016 Apr 10;24(11):557-74. doi: 10.1089/ars.2015.6478. Epub 2016 Mar 16.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion.	Grumolato L, etal., FASEB J. 2008 Jun;22(6):1756-68. Epub 2008 Jan 15.
4.	Se Enhances MLCK Activation by Regulating Selenoprotein T (SelT) in the Gastric Smooth Muscle of Rats.	Li JP, etal., Biol Trace Elem Res. 2016 Sep;173(1):116-25. doi: 10.1007/s12011-016-0620-8. Epub 2016 Jan 18.
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:8889548	PMID:21896670	PMID:23913443	PMID:26280902	PMID:27645994	PMID:30267375	PMID:32686857	PMID:38643121

Genomics

Comparative Map Data

Selenot
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	144,954,324 - 144,971,375 (+)	NCBI		GRCr8
mRatBN7.2	2	142,804,387 - 142,821,438 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	142,804,405 - 142,821,427 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	149,442,810 - 149,459,866 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	147,549,455 - 147,566,511 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	142,181,889 - 142,198,945 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	148,765,412 - 148,781,080 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	148,765,412 - 148,780,276 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	168,183,454 - 168,198,181 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	147,913,245 - 147,929,296 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	147,863,312 - 147,878,392 (+)	NCBI
Celera	2	137,233,019 - 137,248,625 (+)	NCBI		Celera
Cytogenetic Map	2	q26	NCBI

SELENOT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	150,603,321 - 150,630,436 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	150,602,875 - 150,630,436 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	150,321,108 - 150,348,223 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	151,803,756 - 151,830,924 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	148,734,077 - 148,761,252 (+)	NCBI		Celera
Cytogenetic Map	3	q25.1	NCBI
HuRef	3	147,694,723 - 147,721,895 (+)	NCBI		HuRef
CHM1_1	3	150,284,117 - 150,311,288 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	153,354,557 - 153,381,680 (+)	NCBI		T2T-CHM13v2.0

Selenot
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	58,484,057 - 58,500,965 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	58,484,057 - 58,500,554 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	58,576,636 - 58,593,544 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	58,576,636 - 58,593,133 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	58,380,580 - 58,397,466 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	58,664,666 - 58,679,094 (+)	NCBI		MGSCv36	mm8
Celera	3	58,269,653 - 58,286,391 (+)	NCBI		Celera
Cytogenetic Map	3	D	NCBI
cM Map	3	28.61	NCBI

Selenot
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955448	1,795,043 - 1,812,930 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955448	1,794,959 - 1,814,282 (+)	NCBI	ChiLan1.0	ChiLan1.0

SELENOT
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	148,491,999 - 148,519,101 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	148,496,746 - 148,523,830 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	147,620,862 - 147,648,039 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	155,194,428 - 155,221,577 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	155,194,428 - 155,221,578 (+)	Ensembl	panpan1.1		panPan2

SELENOT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	45,247,088 - 45,271,229 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	45,247,088 - 45,271,228 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	45,114,328 - 45,138,461 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	45,875,164 - 45,899,131 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	45,875,146 - 45,900,416 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	45,465,693 - 45,489,652 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	45,517,451 - 45,541,559 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	45,770,350 - 45,794,318 (+)	NCBI		UU_Cfam_GSD_1.0

Selenot
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	90,744,220 - 90,766,089 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936758	1,001,806 - 1,020,877 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936758	1,001,452 - 1,023,582 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SELENOT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	90,818,395 - 90,842,363 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	90,818,409 - 90,839,242 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	99,024,295 - 99,045,163 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SELENOT
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	40,062,259 - 40,094,676 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666041	12,879,715 - 12,913,890 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Selenot
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	28,031,892 - 28,051,769 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Selenot
76 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	50
Count of miRNA genes:	43
Interacting mature miRNAs:	49
Transcripts:	ENSRNOT00000018248
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
2293671	Bss44	Bone structure and strength QTL 44	10.97	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	2	43162366	148478373	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	102803808	147803808	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
6907363	Bp357	Blood pressure QTL 357	4.1	0.002	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	129540907	174540907	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1358360	Sradr2	Stress Responsive Adrenal Weight QTL 2	10.24		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	2	129164097	152195315	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	18960362	228801039	Rat
1581578	Cm49	Cardiac mass QTL 49	4.9	0.01	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	127447387	143657569	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	122609194	206936711	Rat
1549828	Bp258	Blood pressure QTL 258		0.03	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	142323368	150650069	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	76539322	150540526	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	25413423	143657569	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
12879844	Kidm62	Kidney mass QTL 62		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	142323368	146786035	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	114837527	185876470	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
12879841	Cm87	Cardiac mass QTL 87		0.026	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	142323368	146786035	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	136916935	189599348	Rat
12879842	Cm88	Cardiac mass QTL 88		0.042	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	142323368	146786035	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
12879843	Am3	Aortic mass QTL 3		0.016	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	142323368	146786035	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1582257	Gluco21	Glucose level QTL 21	3.1	0.0035	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	118111229	157142209	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1359035	Bp276	Blood pressure QTL 276			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	114837527	143657569	Rat
8662836	Vetf8	Vascular elastic tissue fragility QTL 8	0.66		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	104559726	149559726	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
5135226	Leukc2	Leukocyte quantity QTL 2			eosinophil quantity (VT:0002602)	blood eosinophil count (CMO:0000033)	2	118111229	149559726	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
2299162	Iddm32	Insulin dependent diabetes mellitus QTL 32	2.36		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	78665616	143657569	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
7488933	Bp368	Blood pressure QTL 368		0.004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	142323368	147803808	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
738007	Anxrr7	Anxiety related response QTL 7	4.4		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	118189491	163189491	Rat
9685068	Swd7	Spike wave discharge measurement QTL 7	3.2	0.01	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge rate (CMO:0001739)	2	141656606	147588984	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	157142209	Rat
1581552	Pur12	Proteinuria QTL 12	5.19	0.0009	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	2	112103657	148076632	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
1558653	Prcr1	Prostate cancer resistance QTL 1	5		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	2	72532993	157142209	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	182042367	Rat
1354594	Despr10	Despair related QTL 10		2e-06	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	2	114654253	159654253	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	28484589	169504100	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	28484589	169504100	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	43171017	184114403	Rat

Markers in Region

RH131085

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	142,821,203 - 142,821,405 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	148,782,217 - 148,782,418	NCBI	Rnor6.0
Rnor_5.0	2	168,199,318 - 168,199,519	UniSTS	Rnor5.0
RGSC_v3.4	2	147,930,433 - 147,930,634	UniSTS	RGSC3.4
Celera	2	137,249,762 - 137,249,963	UniSTS
RH 3.4 Map	2	864.9	UniSTS
Cytogenetic Map	2	q31	UniSTS

RH143118

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	142,805,005 - 142,805,106 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	148,766,019 - 148,766,119	NCBI	Rnor6.0
Rnor_5.0	2	168,184,061 - 168,184,161	UniSTS	Rnor5.0
RGSC_v3.4	2	147,913,852 - 147,913,952	UniSTS	RGSC3.4
Celera	2	137,233,626 - 137,233,726	UniSTS
RH 3.4 Map	2	878.8	UniSTS
Cytogenetic Map	2	q31	UniSTS

RH125340

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	142,820,626 - 142,820,809 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	148,781,640 - 148,781,822	NCBI	Rnor6.0
Rnor_5.0	2	168,198,741 - 168,198,923	UniSTS	Rnor5.0
RGSC_v3.4	2	147,929,856 - 147,930,038	UniSTS	RGSC3.4
Celera	2	137,249,185 - 137,249,367	UniSTS
Cytogenetic Map	2	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AA819766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC112531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY995234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC086953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB765038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM042340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM061880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211813	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018248 ⟹ ENSRNOP00000018248

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	142,804,405 - 142,821,427 (+)	Ensembl
Rnor_6.0 Ensembl	2	148,765,412 - 148,780,276 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084662 ⟹ ENSRNOP00000072567

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	148,765,467 - 148,779,565 (+)	Ensembl

RefSeq Acc Id:

NM_001014253 ⟹ NP_001014275

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	144,954,324 - 144,971,375 (+)	NCBI
mRatBN7.2	2	142,804,387 - 142,821,438 (+)	NCBI
Rnor_6.0	2	148,765,412 - 148,781,080 (+)	NCBI
Rnor_5.0	2	168,183,454 - 168,198,181 (+)	NCBI
RGSC_v3.4	2	147,913,245 - 147,929,296 (+)	RGD
Celera	2	137,233,019 - 137,248,625 (+)	RGD

Sequence:

show sequence

GGTTTTGGGCTGCAGTCTCGGTCTGAAGGCGGCCGGAGCGGCTGTCTCAATTAAGATGAGGCTC
TTGCTGCTTCTGCTGGTGGCGGCGTCGGCGGTGGTCCGCAGCGAGGCCTCTGCCAACCTGGGCG
GCGTGCCCAGCAAGAGATTAAAGATGCAGTACGCCACGGGGCCGCTGCTCAAGTTTCAGATTTG
TGTATCCTGAGGGTACAGGCGGGTGTTTGAGGAGTACATGCGGGTTATTAGCCAGCGGTATCCA
GACATCCGCATTGAGGGGGAGAATTATCTCCCTCAACCAATTTATAGACACATAGCATCTTTCC
TGTCAGTCTTCAAACTAGTATTAATAGGCTTAATAATTGTTGGCAAAGATCCTTTTGCTTTTTT
CGGCATGCAAGCTCCTAGCATCTGGCAGTGGGGCCAAGAAAATAAGGTTTATGCATGTATGATG
GTCTTCTTCTTGAGCAACATGATTGAGAACCAGTGTATGTCAACAGGTGCATTTGAGATAACTT
TAAATGATGTACCGGTATGGTCTAAGCTGGAATCTGGACATCTTCCATCCATGCAACAACTTGT
TCAAATTCTTGACAATGAAATGAAACTCAATGTGCATATGGATTCAATCCCACATCATCGATCA
TAGCCCTACCTATCAGCACTGAAAACTCTTTTACACTAAGGGATTTTGCAAGAGCAGCGTGACT
GACATTATGAAGGCCTGTACTGAAGACAGCAAGCTGTTAGTACAGACCAGATGTTTCTTGGCAG
GCTCGTTGTACCTCTTGGAAAACCTCAGTGCAAGACAGTTTTCCATGCTGGCACGTGCTGAACT
CTGCACACACATGCAGTGCAGTGATACTGTGTAGCTTCCCCGAGCCCACTGTTAATAGTTTCTT
CTTGACATGGCATTACTACTTGTAATTCTTTTCTTGGTCATGTTTAAGAAAGTACAGAATTGAG
TTGCAACTTGAGTTTTTTTCAACATGTGTGTTAAGTCGGTTGTGTTTTTATATGAATTTTCATT
TTTTTTAATAGTTAAGCATCAGCTTTCATGGGGCAACACCTGAAGTTCCCAAATAATTTTTAAG
AGTTTCTCAGATAGCTCTAATTGGCCATGTTTAATACATAGTTTTAAAAACACTGCAGATTGTG
AACAGTAAAAATTATACAGGATTATGGGAGAAAATCCAATGTCCAAAATACTCTACCAAGTTGT
GTGTGTGTTGCCTAGTAAGTGTGATATATATGTATGTGTGAGTGAGTGTGTGTGTGTGTGTGTG
TGTGTGTATGTGTGTGTGTGTGTGTGTGAGAGAGAGAGGGGTGGGGGAGAGAGAGAGATTATCA
AGAACAGCAAAACCAACTGCTTTAAAAATCCTATTGTTCAAATTGTCTTGACCAATCTAATAAA
TTAATTAACGGGCCCTTTATACTAAACTAATTTTAGAAAAACTGAGGAGATGTTAAATGAAAAA
GTTTATTGTTCAGTGTATCTGTTAGCATTATTTTTAATAACCATCTGCCTAATTTTTTTGTTTT
TGACTTACAGATAATCTCATAAAGGACATACTTTAGATTCACACATAAGTAATGAGCTAATTTA
CTGTTTTTAGAACAGTTGAAACTCACCTCACTAAAGAACAATTCAGTGAAACCTCTTTACAAAG
TATGTATTATGTAAACGGAGATCATTTGTCTAGTAATTGAATTATCTTAACATCATATATCAGA
ATTTTATTGTATTTGAAAGACAAAATTAAAAATATTTTTAATGTTTAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001014275	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH86953	(Get FASTA)	NCBI Sequence Viewer
	AAY45888	(Get FASTA)	NCBI Sequence Viewer
	EDM14862	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000018248
	ENSRNOP00000018248.6
	ENSRNOP00055025108
	ENSRNOP00060005911
	ENSRNOP00065033483
GenBank Protein	Q1H5H1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001014275 ⟸ NM_001014253
- Peptide Label:	precursor
- UniProtKB:	Q1H5H1 (UniProtKB/Swiss-Prot), F8WFN1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRLLLLLLVAASAVVRSEASANLGGVPSKRLKMQYATGPLLKFQICVSUGYRRVFEEYMRVISQ RYPDIRIEGENYLPQPIYRHIASFLSVFKLVLIGLIIVGKDPFAFFGMQAPSIWQWGQENKVYA CMMVFFLSNMIENQCMSTGAFEITLNDVPVWSKLESGHLPSMQQLVQILDNEMKLNVHMDSIPH HRS hide sequence

Ensembl Acc Id:

ENSRNOP00000018248 ⟸ ENSRNOT00000018248

Ensembl Acc Id:

ENSRNOP00000072567 ⟸ ENSRNOT00000084662

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691343

Promoter ID:

EPDNEW_R1868

Type:

initiation region

Name:

Selenot_1

Description:

selenoprotein T

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	148,765,425 - 148,765,485	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359128	AgrOrtholog
BioCyc Gene	G2FUF-53000	BioCyc
Ensembl Genes	ENSRNOG00000013507	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055018352	UniProtKB/Swiss-Prot
	ENSRNOG00060004707	UniProtKB/Swiss-Prot
	ENSRNOG00065023908	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000018248	UniProtKB/TrEMBL
	ENSRNOT00000018248.7	UniProtKB/Swiss-Prot
	ENSRNOT00055031145	UniProtKB/Swiss-Prot
	ENSRNOT00060007867	UniProtKB/Swiss-Prot
	ENSRNOT00065041002	UniProtKB/Swiss-Prot
Gene3D-CATH	Glutaredoxin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7321890	IMAGE-MGC_LOAD
InterPro	Selenoprotein_Rdx-typ	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Selenoprotein_T	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Thioredoxin-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:365802	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:109481	IMAGE-MGC_LOAD
NCBI Gene	365802	ENTREZGENE
PANTHER	PTHR13544	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Rdx	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Selenot	PhenoGen
RatGTEx	ENSRNOG00000013507	RatGTEx
	ENSRNOG00055018352	RatGTEx
	ENSRNOG00060004707	RatGTEx
	ENSRNOG00065023908	RatGTEx
Superfamily-SCOP	SSF52833	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	F8WFN1	ENTREZGENE, UniProtKB/TrEMBL
	Q1H5H1	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-09-28	Selenot	selenoprotein T	Selt	selenoprotein T	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-09-01	Selt	selenoprotein T	LOC365802	similar to Selenoprotein T	Symbol and Name updated	1299863	APPROVED
2005-07-29	LOC365802	similar to Selenoprotein T			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar