Gene:	HHIP ( Homo sapiens ) hedgehog interacting protein
Description:	This gene encodes a protein similar to the mouse hedgehog-interacting protein, a regulatory component of the hedgehog signalling pathway. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic development, including anteroposterior patterns of limbs and regulation of left-right asymmetry. [provided by RefSeq]
Synonyms:	FLJ90230; HIP; FLJ20992;
Gene Type:	protein-coding
Additional Data
Homologs
Mus musculus: Hhip     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Rattus norvegicus: Hhip     See the Rat gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Hhip RGSC genome assembly v3.4 19 29752098 - 29852337     Cytogenetic 19 q11 Mus musculus Hhip Mouse genome assembly build 36.1 8 82495773 - 82581892     Cytogenetic 8 8 C3 Homo sapiens HHIP human genome assembly 4 145924777 - 146017486     Human genome assembly build 36.2 4 145786623 - 145879331     Cytogenetic 4 q28-q32   View comparative maps:      NCBI MapViewer
Annotation
Molecular Function	Gene Ontology protein binding,  catalytic activity (details...)
Biological Process	Gene Ontology negative regulation of smoothened signaling pathway,  dorsal/ventral pattern formation,  signal transduction ...  (details...)
Cellular Component	Gene Ontology extrinsic to membrane,  extracellular region,  cytoplasm ...  (details...)
External Links
Databases	DATABASE ID SOURCE OMIM: 606178 ENTREZGENE HGNC ID: HHIP ENTREZGENE Entrez Gene: HHIP ENTREZGENE HomoloGene Group ID: 32469 ENTREZGENE HPRD ID: 06937 ENTREZGENE
Sequences	Nucleotide: CH471056 Get FASTA Search GEO Profiles Nucleotide: CS319970 Get FASTA Search GEO Profiles Nucleotide: AK024645 Get FASTA Search GEO Profiles Nucleotide: AK074711 Get FASTA Search GEO Profiles Nucleotide: AK098525 Get FASTA Search GEO Profiles Nucleotide: AK291849 Get FASTA Search GEO Profiles Nucleotide: AY009317 Get FASTA Search GEO Profiles Nucleotide: AY009951 Get FASTA Search GEO Profiles Nucleotide: AY358747 Get FASTA Search GEO Profiles Nucleotide: BC009298 Get FASTA Search GEO Profiles Nucleotide: BC015636 Get FASTA Search GEO Profiles Nucleotide: BC025311 Get FASTA Search GEO Profiles Nucleotide: NG_011496 Get FASTA Search GEO Profiles Nucleotide: NM_022475 Get FASTA Search GEO Profiles Nucleotide: AF326471 Get FASTA Search GEO Profiles Nucleotide: AC098588 Get FASTA Search GEO Profiles (View all 16 Nucleotide Accessions) Protein: CAK96038 Get FASTA Protein: EAX05054 Get FASTA Protein: AAK18182 Get FASTA Protein: AAG34731 Get FASTA Protein: NP_071920 Get FASTA Protein: AAQ89107 Get FASTA Protein: AAH09298 Get FASTA Protein: ABM84544 Get FASTA Protein: AAH25311 Get FASTA Protein: Q96QV1 Get FASTA Protein: AAG35411 Get FASTA Protein: BAF84538 Get FASTA Protein: BAC11154 Get FASTA Protein: BAB14945 Get FASTA (View all 14 Protein Accessions)
Clusters	UniGene: 507991
References
Curated References	There are currently no references in RGD related to HHIP
Other References	18 other references at PubMed related to HHIP
Database Information
RGD ID	1354359
History	No Nomenclature events are recorded for this object