Or6c35d (olfactory receptor family 6 subfamily C member 35D) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Or6c35d (olfactory receptor family 6 subfamily C member 35D) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or6c35d
Name: olfactory receptor family 6 subfamily C member 35D
RGD ID: 1333844
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane; INTERACTS WITH C60 fullerene; cadmium dichloride; copper atom.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC100910170; LOC108348036; olfactory receptor 6C2-like; olfactory receptor 921; olfactory receptor gene Olr921; olfactory receptor Olr921; Olr921
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr873,478,247 - 3,479,182 (-)NCBIGRCr8
mRatBN7.272,829,238 - 2,830,173 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl72,829,238 - 2,830,173 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx75,672,604 - 5,673,539 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.077,548,279 - 7,549,214 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.073,900,228 - 3,901,163 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl716,035,250 - 16,036,185 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,889,136 - 3,890,071 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.474,080,503 - 4,081,438 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.174,080,502 - 4,081,438 (-)NCBI
Celera71,848,412 - 1,849,347 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or6c35d
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:116
Count of miRNA genes:44
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000047899, ENSRNOT00000071350
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001001385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000047899   ⟹   ENSRNOP00000043905
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl72,829,238 - 2,830,173 (-)Ensembl
Rnor_6.0 Ensembl716,035,250 - 16,036,185 (-)Ensembl
RefSeq Acc Id: NM_001001385   ⟹   NP_001001385
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr873,478,247 - 3,479,182 (-)NCBI
mRatBN7.272,829,238 - 2,830,173 (-)NCBI
Rnor_6.073,900,228 - 3,901,163 (+)NCBI
Rnor_5.073,889,136 - 3,890,071 (+)NCBI
RGSC_v3.474,080,503 - 4,081,438 (-)RGD
Celera71,848,412 - 1,849,347 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001001385 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000043905
  ENSRNOP00000043905.1
Reference Protein Sequences
RefSeq Acc Id: NP_001001385   ⟸   NM_001001385
- UniProtKB: D3ZC13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000043905   ⟸   ENSRNOT00000047899
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZC13-F1-model_v2 AlphaFold D3ZC13 1-311 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333844 AgrOrtholog
BioCyc Gene G2FUF-35267 BioCyc
Ensembl Genes ENSRNOG00000049242 Ensembl
  ENSRNOG00000068317 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047899 ENTREZGENE
  ENSRNOT00000047899.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfact_rcpt_6C-like UniProtKB/TrEMBL
KEGG Report rno:366798 UniProtKB/TrEMBL
NCBI Gene 366798 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or6c35d PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049242 RatGTEx
  ENSRNOG00000068317 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt D3ZC13 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or6c35d  olfactory receptor family 6 subfamily C member 35D  Olr921  olfactory receptor 921  Symbol and Name Changed 1299863 APPROVED
2021-03-09 Olr921  olfactory receptor 921  LOC108348036  olfactory receptor 6C2-like  Data merged from RGD:11491185 737654 PROVISIONAL
2016-08-02 LOC108348036  olfactory receptor 6C2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2015-07-29 Olr921  olfactory receptor 921  LOC100910170  olfactory receptor 6C2-like  Data merged from RGD:6499744 737654 PROVISIONAL
2012-07-05 LOC100910170  olfactory receptor 6C2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr921  olfactory receptor 921   Olr921_predicted  olfactory receptor 921 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr921_predicted  olfactory receptor 921 (predicted)      Symbol and Name status set to approved 70820 APPROVED