Or51l1 (olfactory receptor family 51 subfamily L member 1) - Rat Genome Database

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Gene: Or51l1 (olfactory receptor family 51 subfamily L member 1) Rattus norvegicus
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Symbol: Or51l1
Name: olfactory receptor family 51 subfamily L member 1
RGD ID: 1333532
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be active in plasma membrane. Orthologous to human OR51L1 (olfactory receptor family 51 subfamily L member 1); INTERACTS WITH bisphenol A; furan; lead diacetate.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 78; olfactory receptor gene Olr78; olfactory receptor Olr78; Olr78; ratchr1-160945784-160946731_ORF
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81166,928,111 - 166,929,058 (+)NCBIGRCr8
mRatBN7.21157,516,210 - 157,517,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1157,516,210 - 157,517,157 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1165,490,278 - 165,491,225 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01172,670,377 - 172,671,324 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,560,452 - 165,561,399 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,237,950 - 168,238,897 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,237,950 - 168,238,897 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,411,847 - 174,412,794 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41160,866,763 - 160,867,710 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11160,945,783 - 160,946,731 (+)NCBI
Celera1155,563,156 - 155,564,103 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51l1Ratdelta beta-thalassemia  ISOOR51L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Thalassemia and gamma-delta-betaClinVarPMID:2798417


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51l1Ratbenzo[a]pyrene decreases methylationISOOR51L1 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of OR51L1 promoterCTDPMID:27901495
Or51l1Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of OR51L1 mRNACTDPMID:25181051
Or51l1Ratfuran increases methylationEXP 6480464furan results in increased methylation of OR51L1 geneCTDPMID:22079235
Or51l1Ratlead diacetate decreases expressionEXP 6480464lead acetate results in decreased expression of OR51L1 mRNACTDPMID:22641619


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51l1Ratdetection of chemical stimulus involved in sensory perception of smell involved_inIEAGO:00049841600115GO_REF:0000108GOCGO_REF:0000108
Or51l1Ratdetection of chemical stimulus involved in sensory perception of smell  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or51l1RatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or51l1RatG protein-coupled receptor signaling pathway  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51l1Ratplasma membrane is_active_inIBAMGI:2157548 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51l1RatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or51l1Ratolfactory receptor activity enablesIBAPANTHER:PTN002816874 and UniProtKB:Q9H2551600115GO_REF:0000033GO_CentralGO_REF:0000033
Or51l1Ratolfactory receptor activity  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51l1Rattaste/olfaction phenotype  IEA 1303377 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


Or51l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81166,928,111 - 166,929,058 (+)NCBIGRCr8
mRatBN7.21157,516,210 - 157,517,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1157,516,210 - 157,517,157 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1165,490,278 - 165,491,225 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01172,670,377 - 172,671,324 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,560,452 - 165,561,399 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,237,950 - 168,238,897 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,237,950 - 168,238,897 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,411,847 - 174,412,794 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41160,866,763 - 160,867,710 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11160,945,783 - 160,946,731 (+)NCBI
Celera1155,563,156 - 155,564,103 (+)NCBICelera
Cytogenetic Map1q32NCBI
OR51L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38114,994,851 - 5,005,536 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl114,994,851 - 5,005,536 (+)EnsemblGRCh38hg38GRCh38
GRCh37115,016,081 - 5,026,766 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36114,976,789 - 4,977,736 (+)NCBINCBI36Build 36hg18NCBI36
Build 34114,976,788 - 4,977,736NCBI
Celera115,135,404 - 5,136,351 (+)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef114,678,829 - 4,679,776 (+)NCBIHuRef
CHM1_1115,019,133 - 5,020,080 (+)NCBICHM1_1
T2T-CHM13v2.0115,051,790 - 5,062,460 (+)NCBIT2T-CHM13v2.0
Or51l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397102,783,583 - 102,784,530 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7102,783,583 - 102,784,530 (+)EnsemblGRCm39 Ensembl
GRCm387103,134,376 - 103,135,323 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7103,134,376 - 103,135,323 (+)EnsemblGRCm38mm10GRCm38
MGSCv377110,282,890 - 110,283,837 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367103,008,197 - 103,009,144 (+)NCBIMGSCv36mm8
Celera7103,494,287 - 103,495,234 (+)NCBICelera
Cytogenetic Map7E3NCBI
cM Map754.85NCBI
OR51L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12127,435,270 - 27,436,993 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2127,435,775 - 27,436,722 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2127,202,050 - 27,203,012 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02128,061,824 - 28,062,786 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2128,061,839 - 28,062,786 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12127,484,031 - 27,484,993 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02127,746,734 - 27,747,696 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02127,796,397 - 27,797,359 (+)NCBIUU_Cfam_GSD_1.0
LOC100525652
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl95,180,480 - 5,181,427 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.195,178,714 - 5,183,143 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

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Variants in Or51l1
3 total Variants

Predicted Target Of
Summary Value
Count of predictions:30
Count of miRNA genes:29
Interacting mature miRNAs:30
Transcripts:ENSRNOT00000021098
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 78 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4889419Cstrr2Cold stress response QTL 20.05urine catecholamine amount (VT:0010502)absolute change in urine norepinephrine level (CMO:0001634)1155866514158592016Rat
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat

1 to 10 of 78 rows



alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
nervous system
reproductive system
respiratory system
2 6 1 4 1 1 3 6 1 3



Ensembl Acc Id: ENSRNOT00000021098   ⟹   ENSRNOP00000021098
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1157,516,210 - 157,517,157 (+)Ensembl
Rnor_6.0 Ensembl1168,237,950 - 168,238,897 (+)Ensembl
RefSeq Acc Id: NM_001000135   ⟹   NP_001000135
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81166,928,111 - 166,929,058 (+)NCBI
mRatBN7.21157,516,210 - 157,517,157 (+)NCBI
Rnor_6.01168,237,950 - 168,238,897 (+)NCBI
Rnor_5.01174,411,847 - 174,412,794 (+)NCBI
RGSC_v3.41160,866,763 - 160,867,710 (+)RGD
Celera1155,563,156 - 155,564,103 (+)RGD
Sequence:
Protein RefSeqs NP_001000135 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM18147 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021098.3
RefSeq Acc Id: NP_001000135   ⟸   NM_001000135
- UniProtKB: D4ABJ3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021098   ⟸   ENSRNOT00000021098
Name Modeler Protein Id AA Range Protein Structure
AF-D4ABJ3-F1-model_v2 AlphaFold D4ABJ3 1-315 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 21 of 21 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-58191 BioCyc
Ensembl Genes ENSRNOG00000015760 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021098.4 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_rcpt UniProtKB/TrEMBL
KEGG Report rno:293221 UniProtKB/TrEMBL
NCBI Gene 293221 ENTREZGENE
PANTHER OLFACTORY RECEPTOR 51L1 UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 56B1-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or51l1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015760 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt D4ABJ3 ENTREZGENE, UniProtKB/TrEMBL
1 to 21 of 21 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or51l1  olfactory receptor family 51 subfamily L member 1  Olr78  olfactory receptor 78  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr78  olfactory receptor 78   Olr78_predicted  olfactory receptor 78 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr78_predicted  olfactory receptor 78 (predicted)      Symbol and Name status set to approved 70820 APPROVED