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Gene: Klhl26 (kelch-like family member 26) Rattus norvegicus

Analyze

Symbol:

Klhl26

Name:

kelch-like family member 26

RGD ID:

1312034

Description:

Orthologous to human KLHL26 (kelch like family member 26); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

kelch-like 26; kelch-like 26 (Drosophila); kelch-like protein 26; LOC290657; RGD1312034; similar to hypothetical protein MGC38024

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KLHL26 (kelch like family member 26)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Klhl26 (kelch-like 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Klhl26 (kelch like family member 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KLHL26 (kelch like family member 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KLHL26 (kelch like family member 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Klhl26 (kelch like family member 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KLHL26 (kelch like family member 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KLHL26 (kelch like family member 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Klhl26 (kelch like family member 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Klhl26 (kelch like family member 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Klhl26 (kelch-like 26)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	KLHL26 (kelch like family member 26)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	klhl26 (kelch-like family member 26)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	klhl26 (kelch-like family member 26)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG1812	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|PANTHER)
Drosophila melanogaster (fruit fly):	CG1812	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	klhl26	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	klhl26	Alliance	DIOPT (OMA\|OrthoFinder)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	18,986,095 - 19,011,297 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	18,985,865 - 19,011,297 (+)	Ensembl				GRCr8
mRatBN7.2	16	18,952,123 - 18,977,328 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	18,952,234 - 18,977,328 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	18,994,256 - 19,019,326 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	20,126,822 - 20,151,867 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	19,047,218 - 19,072,285 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	20,704,807 - 20,729,882 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	20,704,807 - 20,729,882 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	20,557,872 - 20,582,253 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	19,458,655 - 19,483,636 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	19,143,582 - 19,168,670 (+)	NCBI		Celera
RGSC_v3.1	16	19,455,256 - 19,481,709 (+)	NCBI
Cytogenetic Map	16	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (EXP)

Aflatoxin B2 alpha (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

cadmium dichloride (EXP,ISO)

chlormequat chloride (EXP)

choline (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

doxorubicin (ISO)

etoposide (ISO)

fenthion (ISO)

folic acid (ISO)

L-methionine (ISO)

methapyrilene (ISO)

methidathion (ISO)

methimazole (EXP)

methoxychlor (EXP)

ozone (ISO)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

propiconazole (EXP)

sodium arsenite (ISO)

Soman (EXP)

testosterone (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

Triptolide (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteasome-mediated ubiquitin-dependent protein catabolic process (IBA)

Cellular Component

Cul3-RING ubiquitin ligase complex (IBA)

Molecular Function

protein binding (ISO)

ubiquitin-like ligase-substrate adaptor activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Klhl26
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	18,986,095 - 19,011,297 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	18,985,865 - 19,011,297 (+)	Ensembl				GRCr8
mRatBN7.2	16	18,952,123 - 18,977,328 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	18,952,234 - 18,977,328 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	18,994,256 - 19,019,326 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	20,126,822 - 20,151,867 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	19,047,218 - 19,072,285 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	20,704,807 - 20,729,882 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	20,704,807 - 20,729,882 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	20,557,872 - 20,582,253 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	19,458,655 - 19,483,636 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	19,143,582 - 19,168,670 (+)	NCBI		Celera
RGSC_v3.1	16	19,455,256 - 19,481,709 (+)	NCBI
Cytogenetic Map	16	p14	NCBI

KLHL26
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	18,637,028 - 18,671,721 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	18,637,025 - 18,671,721 (+)	Ensembl			hg38	GRCh38
GRCh37	19	18,747,838 - 18,782,531 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	18,608,838 - 18,642,302 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	19	18,650,015 - 18,683,043 (+)	NCBI		Celera
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	18,309,255 - 18,342,335 (+)	NCBI		HuRef
CHM1_1	19	18,747,955 - 18,781,366 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	18,772,095 - 18,806,817 (+)	NCBI		T2T-CHM13v2.0

Klhl26
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	70,902,868 - 70,929,660 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	70,902,869 - 70,929,618 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	70,450,218 - 70,476,989 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	70,450,219 - 70,476,968 (-)	Ensembl			mm10	GRCm38
MGSCv37	8	72,974,127 - 73,000,842 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	73,379,216 - 73,405,938 (-)	NCBI		MGSCv36	mm8
Celera	8	73,006,789 - 73,033,356 (-)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	34.15	NCBI

Klhl26
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955524	2,947,402 - 2,964,192 (-)	NCBI	ChiLan1.0	ChiLan1.0

KLHL26
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	23,496,665 - 23,530,399 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	22,505,107 - 22,540,043 (+)	NCBI		NHGRI_mPanPan1
PanPan1.1 Ensembl	19	19,086,145 - 19,117,456 (+)	Ensembl			panPan2	panpan1.1

KLHL26
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	44,404,228 - 44,432,467 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	44,404,352 - 44,432,472 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	44,316,293 - 44,347,047 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	44,887,958 - 44,918,735 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	44,890,597 - 44,918,739 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	44,125,388 - 44,156,145 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	44,535,343 - 44,566,108 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	44,813,296 - 44,841,547 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Klhl26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	203,085,439 - 203,113,678 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936596	2,632,398 - 2,662,771 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936596	2,634,578 - 2,662,767 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KLHL26
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	59,166,126 - 59,193,948 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	59,166,118 - 59,193,948 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	58,920,086 - 58,947,882 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KLHL26
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	17,100,921 - 17,134,508 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666074	2,192,875 - 2,232,482 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Klhl26
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624908	1,802,351 - 1,807,345 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624908	1,783,965 - 1,806,524 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Klhl26
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	13	12,707,631 - 12,731,338 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Klhl26
214 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	387
Count of miRNA genes:	213
Interacting mature miRNAs:	254
Transcripts:	ENSRNOT00000027241
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1549842	Bp248	Blood pressure QTL 248		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	387123	45387123	Rat
2307172	Activ4	Activity QTL 4	3.71	0.00023	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	1	33425095	Rat
1354584	Despr6	Despair related QTL 6	3.1	0.0067	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	39568015	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4234212	53708481	Rat
631517	Scl9	Serum cholesterol level QTL 9	3.3		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	16	15748006	25801629	Rat
1354625	Despr7	Despair related QTL 7	3.16	0.016	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	4744222	49744222	Rat
61405	Niddm6	Non-insulin dependent diabetes mellitus QTL 6	3.66	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	16	1	26734272	Rat
631830	Alc7	Alcohol consumption QTL 7	2.9		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	1	26734272	Rat
7411664	Foco30	Food consumption QTL 30	11	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	4354822	49354822	Rat
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	16	387123	45387123	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	4234212	49757901	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	66955197	Rat
1600369	Hcas8	Hepatocarcinoma susceptibility QTL 8			liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	16	16278184	27244292	Rat
2303566	Bw90	Body weight QTL 90	2		body mass (VT:0001259)	body weight (CMO:0000012)	16	1	39568015	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	839086	66195506	Rat
2306902	Bp339	Blood pressure QTL 339		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	3386790	49757901	Rat
1300133	Rf24	Renal function QTL 24	3.64		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	16	3386790	26128267	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	839086	66195506	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	839086	66195506	Rat
634355	Rends4	Renal damage susceptibility QTL 4		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	16	1	26734272	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17730818	72536785	Rat
2293343	Glom16	Glomerulus QTL 16	7.4		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	16	839086	52786090	Rat
2301406	Kidm39	Kidney mass QTL 39		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	16	15905802	60905802	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	839086	66195506	Rat
6903319	Bw114	Body weight QTL 114	2.7	0.0037	body mass (VT:0001259)	body weight (CMO:0000012)	16	3301683	48301683	Rat

Markers in Region

RH143562

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	18,976,139 - 18,976,292 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	20,728,694 - 20,728,846	NCBI	Rnor6.0
Rnor_5.0	16	20,581,065 - 20,581,217	UniSTS	Rnor5.0
RGSC_v3.4	16	19,482,448 - 19,482,600	UniSTS	RGSC3.4
Celera	16	19,167,482 - 19,167,634	UniSTS
RH 3.4 Map	16	238.71	UniSTS
Cytogenetic Map	16	p14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	85	59	6	348	185	11	140	80	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094333	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027241 ⟹ ENSRNOP00000027240

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	18,986,060 - 19,010,373 (+)	Ensembl
mRatBN7.2 Ensembl	16	18,952,234 - 18,977,328 (+)	Ensembl
Rnor_6.0 Ensembl	16	20,704,807 - 20,729,882 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000127686 ⟹ ENSRNOP00000105393

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	18,985,865 - 19,011,297 (+)	Ensembl

RefSeq Acc Id:

NM_001106075 ⟹ NP_001099545

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	18,986,207 - 19,011,297 (+)	NCBI
mRatBN7.2	16	18,952,234 - 18,977,328 (+)	NCBI
Rnor_6.0	16	20,704,807 - 20,729,882 (+)	NCBI
Rnor_5.0	16	20,557,872 - 20,582,253 (+)	NCBI
RGSC_v3.4	16	19,458,655 - 19,483,636 (+)	RGD
Celera	16	19,143,582 - 19,168,670 (+)	RGD

Sequence:

show sequence

CAGGTTCCGCCCGCTGCCCAGGCCTCGGTCTCCGGGTCCGCGCGCCGCTCCATCGCTCGGGCGC
GCGGCGGAAGATGGCGGAGTCCGGCGGCAGCAGCGGCTCTGGCCAGAGCCCCGAGCGCCCGAGC
AGCTTGGCTGACAGGAATGGGGCCCTCAAGTGCACCTTCTCTGCGGCTGGCCATAGCACTGGCC
TCCTGCAGGGCCTGGCTGCCCTCCGTGCACAGGGCCAGCTGCTCGATGTGGTCCTCACTGTCAA
CAGTGAAGCCTTCCATGCACACAAGGTGGTCTTGGCGGCCTGCAGTGACTACTTTAGGGCCATG
TTCACTGGCGGCATGCGTGAGGCCAGCCAGGCCGTCATCCAGCTGCAGGGTGTGTCTGCACGTG
GCCTGCGTCACATCATCGATTTCGCCTACAGTGCTGAGGTAACACTGGACCTAGACTGTGTGCA
GGATGTGCTGGGTGCTGCCGTGTTTCTGCAGATGCTGCCGGTGGTGGAGCTGTGCGAGGACTTC
CTAAAAGCTGCCATGAGCGTAGAGACGTGCCTGCACATTGGCCAGATGGCTACCACCTTCAGCC
TGACATCACTTCGTGAGTCAGTAGATGCCTTCACATTCCGCCACTTTCTGCAGATAGCAGCAGA
GGAGGACTTTCTGCGCCTGCCACTCGAGCGCCTTGTCTTCTTTCTGCAGAGCAACCGGCTACAG
AGTTGTGCAGAGATTGACCTGTTCCGTGCTGCTGTGCGCTGGCTGCAGCACGATCCGGCCCGCC
GTGCCCGCGCCAGCCTCGTGCTACGCCATGTGCGCTTCCCGCTCATGCAGCCTGCTGAGCTGGT
GGACAGTGTGCAGACACTCGACGTCATGCTGGACGATGCCCTGTGTCGCCAGTACCTGCTGGAG
GCCTTCAGCTACCACGTGCTGCCCTGCCGCCAGCATGACATGCAGTCTCCACGCACAGCTGTGC
GCTCCGATGTGGCGTCCCTGGTGGCCTTCGGAGGCACACCGTATACCGACAGTGACCGAGCTGT
CAGCAGCAAGGTGTTCCAGTTGCCTGAGCCTGGGGCCCGCCACTTCCGCGAGCTCACGGAGATG
GAACTGGGCTGCAGCCACGCGGGCGTGGCTGTGCTGGATAACTTCGTGTACGTGGCTGGCGGCC
AGCACCTGCAGCACCGCAGTGGCGAGGGCGCCGTGGACGCCTGCTACCGCTATGATCCACAGCG
CAATCGCTGGCTGCGGCTGCGGGCACTGCGTGAGAGCCGCGTACAGTTCCAGCTCACTGCACTG
GGTGGGCTGCTGTATGCCACTGGTGGCCGCAATCGTGCGGGCAGCCTGGCGTCTGTCGAGCGCT
ACTGCCCACGCCGCGACAGCTGGGACTTTGCCTGCCCACTCAAGCGCCGCACCTGGGGCCACGC
GGGGGCTGCGGCTGCTGGTCGCCTCTACATCTCGGGTGGCTATGGCGTCTCAGCGGAGGACAAG
AAGGCACTGCAGTGCTATGATCCAGCAGCCGACCGATGGGAACCCAGGGCGCCCATGCGTGAGC
CCCGCGTGCTGCACGCTATGTTGGGCGCTGCTGGCCGCATCTATGCCCTAGGTGGCCGCATGGA
CCACGTGGACCGCTGCTTTGATGTGTTGGCTGTGGAGTACTACGTGCCAGATGCTGACCAGTGG
ACCAGTGTGACCCCCATGCGTGCTGGTCAGTCAGAAGCTGGCTGCTGCCTGCTGGAGAGGAAGA
TCTACATTGTGGGTGGCTACAACTGGAGGCTGAACAATGTCACAGGCATTGTGCAGGTGTACAA
CACTGAGACGGATGAGTGGGAGAGAGACCTGCACTTCCCCGAGTCCTTTGCAGGCATTGCCTGT
GCTGCTGTCCTGCTGCCCCGCTCAGGTCATGGGAGGTAGCGCGGGATCCCGGCCTGGCTGTGTT
CCCCACAGGTGTAGACCCCGGCTAGGGGCTCCCCACCTCCCAGCCCCAAGTCAGCAGAGAGATC
TGGTCCCAAAGGTTTGGGCACCATGGCAGCCGTTGCCTAAGGGAAGACCTGCTCTGTCCTGTGT
TGTTAGGTCTTGATTTCCCACAACCCTAGCCCAACAGACAGAAGCTTGTAGATGTAAAGCACCC
AGTCCTGGGAGAAACAGCTCTCCCTGTCTCCTGACTGAAATCTTCTGTCCAAATCCTAGCCTGG
ATTTCCCCATGGGATCCACAGGCAGAGAGAGACTGCTCAGACTTACCCTCTGAACTCCATGCAG
GCACCATGGAACACTCATGCACGCACACAATCAAATGAGCAAGGTTGTAAATCAGCTCTCGGGT
GCCTGGACAGCATTCAGGAGCCAGGAGCCAGAGAGTTTCCCAGAGGCACCCTGACAGGTGACAG
ATGCAGCCAAGCTCCCTGTCTGCCTTGACTTGTGGACTCCGGAGCATCCCAAAGAGGCTCCCTG
TCCAGTTAACCCAGCATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCCGGAGCTGGGGACCGAA
CCCAGGGCCTTGCGCTTCCTAGGTAAGCGCTCTACCACTGAGCTAAATCCCCAGCCCCTATAAC
CCAGCATTCTTTGCCTGTGCCATCCACTTGTAGAAGAACACCAAGCCAAGTGTGGCCTGTTCGG
TACTCTGGAGGCTAATGAGGGAGGGTCATTGTGAGTCCCTGGCCAGCCAGGGCCTCAAAATAAG
ACTGTCTCAAAGCCCCAAAACATCGAGGAAATCCACAGAAACCAAAAGCAGAGGAAACACGAAA
GCCACCTCAGGTGAGGTAGCCTGTCAGATGGCCTGGGAGGAGAGCCAGCCGGGTGCCCATCTCC
TATGTTCGCTGCAGAAAGCCATGTCCCCAGGTCTGGCCCACCCAGGGTGGGGTGGTGGGAAGTG
CTATGACAGCATGAACCCCAGCAGCCTCCCAAGATGGCAGCCTGCTGTTTTGCTGTTTAAACCC
TGAACTCTCACCCTCATGTTTTCTTTGTTTCTTATTTAAGGAAGCCAGCCCCACTGTCTTCCAA
ATGAGAGTGTTCTCTGGTGATCTAAACTGTCCCCTGCTGCTCACAGACGCGGATGTCACCATTG
TGCGGCCGCTCGGCACATGAGTAATTAACCCTAGTCCTTTGCCTCAGCCTCTGCTGACAAGTCC
TTTGATTTAATAAAGGCGTTATGGAGGAAGGATGGAGCAGACCTGGTGTTCAGTCCCTGCAGCC
TGTGTGACCTCGGGCTTAGGGGGCCCCTCTCTATCTCCTTTTCTCCAACCTCCCTGCTGAACAG
GGAGCTGCAGGGCTGCTGCGTGTCTGGGCTGGGCTTAGGGGCCAGGCTTGTTGGGCAGCCTAGA
AGAGGAGTACACAGGAGGCCGTGGAGGGACCTCTTCATAGGAGGCTACAGCCCCCAGGAGCTAC
AGTCTCTGCTCAGTCATACCCCCCAACTGCAGATAAGCTTCTGAGGCCATGGTTGGTCAGTCAG
CAGACCTGTCTCCATTCTCCCAGAGGCTTCCCCTGTCGGGGAGGGGGTGACCTTCAGGATCCTT
GCCCTAGCCCAGCACAGGATCACAGTTGGGGACAAGTGACTGACACTCAGAACAGTTCACTAAG
AAGACTTATGTTGTCCCCTCCACCTCATCCCAAGATCACTTCCCTGCTATTCCAGCCACCTCCT
CAGTAAGGCTCAGGTGGTGGCTACTAAAATCCGAACTGATCTATAGCCCAGGCTGCCAGGGCTC
CAAGCAACCCACGGAGACATTCTAGCTGCCTTCTGCAGAGGGGCAGGGTGAAGTGTCTGCCAGC
CACAAGTCCCCCAGATCACATAGCACCTCACAACATCTTGTCCC

hide sequence

RefSeq Acc Id:

XM_039094333 ⟹ XP_038950261

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	18,986,095 - 19,010,642 (+)	NCBI
mRatBN7.2	16	18,952,123 - 18,976,680 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099545	(Get FASTA)	NCBI Sequence Viewer
	XP_038950261	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL90683	(Get FASTA)	NCBI Sequence Viewer
	EDL90684	(Get FASTA)	NCBI Sequence Viewer
	EDL90685	(Get FASTA)	NCBI Sequence Viewer
	EDL90686	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027240.6
	ENSRNOP00000105393
	ENSRNOP00000105393.1

RefSeq Acc Id:

NP_001099545 ⟸ NM_001106075

- UniProtKB:

D3ZH92 (UniProtKB/TrEMBL), A6KA51 (UniProtKB/TrEMBL), A6KA52 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAESGGSSGSGQSPERPSSLADRNGALKCTFSAAGHSTGLLQGLAALRAQGQLLDVVLTVNSEA
FHAHKVVLAACSDYFRAMFTGGMREASQAVIQLQGVSARGLRHIIDFAYSAEVTLDLDCVQDVL
GAAVFLQMLPVVELCEDFLKAAMSVETCLHIGQMATTFSLTSLRESVDAFTFRHFLQIAAEEDF
LRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRARASLVLRHVRFPLMQPAELVDSV
QTLDVMLDDALCRQYLLEAFSYHVLPCRQHDMQSPRTAVRSDVASLVAFGGTPYTDSDRAVSSK
VFQLPEPGARHFRELTEMELGCSHAGVAVLDNFVYVAGGQHLQHRSGEGAVDACYRYDPQRNRW
LRLRALRESRVQFQLTALGGLLYATGGRNRAGSLASVERYCPRRDSWDFACPLKRRTWGHAGAA
AAGRLYISGGYGVSAEDKKALQCYDPAADRWEPRAPMREPRVLHAMLGAAGRIYALGGRMDHVD
RCFDVLAVEYYVPDADQWTSVTPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTET
DEWERDLHFPESFAGIACAAVLLPRSGHGR

hide sequence

Ensembl Acc Id:

ENSRNOP00000027240 ⟸ ENSRNOT00000027241

RefSeq Acc Id:	XP_038950261 ⟸ XM_039094333
- Peptide Label:	isoform X1
- UniProtKB:	A6KA53 (UniProtKB/TrEMBL), A6KA54 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000105393 ⟸ ENSRNOT00000127686

Protein Domains

BACK BTB

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZH92-F1-model_v2	AlphaFold	D3ZH92	1-606	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700032

Promoter ID:

EPDNEW_R10555

Type:

initiation region

Name:

Klhl26_1

Description:

kelch-like family member 26

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	20,704,836 - 20,704,896	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1312034	AgrOrtholog
BioCyc Gene	G2FUF-11780	BioCyc
Ensembl Genes	ENSRNOG00000020088	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000027241.7	UniProtKB/TrEMBL
	ENSRNOT00000127686	ENTREZGENE
	ENSRNOT00000127686.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.420	UniProtKB/TrEMBL
	2.120.10.80	UniProtKB/TrEMBL
	Potassium Channel Kv1.1, Chain A	UniProtKB/TrEMBL
InterPro	BACK	UniProtKB/TrEMBL
	BTB/POZ-like	UniProtKB/TrEMBL
	BTB/POZ_fold	UniProtKB/TrEMBL
	Kelch-like_gigaxonin	UniProtKB/TrEMBL
	Kelch-typ_b-propeller	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
	KLHL26	UniProtKB/TrEMBL
KEGG Report	rno:290657	UniProtKB/TrEMBL
NCBI Gene	290657	ENTREZGENE
PANTHER	LD33804P	UniProtKB/TrEMBL
	PTHR45632:SF13	UniProtKB/TrEMBL
Pfam	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
	KLHL33-like_BTB_POZ	UniProtKB/TrEMBL
PhenoGen	Klhl26	PhenoGen
PIRSF	Kelch-like_protein_gigaxonin	UniProtKB/TrEMBL
PROSITE	BTB	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000020088	RatGTEx
SMART	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch	UniProtKB/TrEMBL
Superfamily-SCOP	BTB/POZ_fold	UniProtKB/TrEMBL
	SSF117281	UniProtKB/TrEMBL
UniProt	A0ABK0LIM8_RAT	UniProtKB/TrEMBL
	A6KA51	ENTREZGENE, UniProtKB/TrEMBL
	A6KA52	ENTREZGENE, UniProtKB/TrEMBL
	A6KA53	ENTREZGENE, UniProtKB/TrEMBL
	A6KA54	ENTREZGENE, UniProtKB/TrEMBL
	D3ZH92	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-02-27	Klhl26	kelch-like family member 26	Klhl26	kelch-like 26 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Klhl26	kelch-like 26 (Drosophila)	Klhl26_predicted	kelch-like 26 (Drosophila) (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Klhl26_predicted	kelch-like 26 (Drosophila) (predicted)	RGD1312034_predicted	similar to hypothetical protein MGC38024 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1312034_predicted	similar to hypothetical protein MGC38024 (predicted)	LOC290657_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC290657_predicted	similar to hypothetical protein MGC38024 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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