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Gene: Rnf20 (ring finger protein 20) Rattus norvegicus

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Symbol:

Rnf20

Name:

ring finger protein 20

RGD ID:

1311936

Description:

Predicted to enable several functions, including histone H2B C-terminal K residue ubiquitin ligase activity; histone binding activity; and p53 binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including positive regulation of transcription by RNA polymerase II; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in nucleolus. Predicted to be part of HULC complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human RNF20 (ring finger protein 20); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; diuron.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

E3 ubiquitin-protein ligase BRE1A; LOC313216; ring finger protein 20, E3 ubiquitin protein ligase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RNF20 (ring finger protein 20)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Rnf20 (ring finger protein 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rnf20 (ring finger protein 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RNF20 (ring finger protein 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RNF20 (ring finger protein 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnf20 (ring finger protein 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RNF20 (ring finger protein 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RNF20 (ring finger protein 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnf20 (ring finger protein 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rnf20 (ring finger protein 20)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	OR51Q1 (olfactory receptor family 51 subfamily Q member 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RNF20 (ring finger protein 20)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RNF20 (ring finger protein 20)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Mus musculus (house mouse):	Rnf20 (ring finger protein 20)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rnf20 (ring finger protein 20)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	rnf20 (ring finger protein 20, E3 ubiquitin protein ligase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rnf20 (ring finger protein 20, E3 ubiquitin protein ligase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Bre1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Bre1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	BRE1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	BRE1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rfp-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rfp-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rnf20	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rnf20	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	68,771,507 - 68,797,240 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	68,771,535 - 68,797,240 (+)	Ensembl				GRCr8
mRatBN7.2	5	63,976,063 - 64,001,754 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	63,976,045 - 64,001,754 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	65,909,405 - 65,935,039 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	67,728,751 - 67,754,385 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	67,698,118 - 67,723,752 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	64,892,996 - 64,920,397 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	64,892,802 - 64,920,390 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	69,386,793 - 69,411,969 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	66,371,470 - 66,397,538 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	63,606,822 - 63,632,554 (-)	NCBI		Celera
RGSC_v3.1	5	66,376,582 - 66,402,649 (+)	NCBI
Cytogenetic Map	5	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute biphenotypic leukemia (ISO)

Arsenic Poisoning (ISO)

breast cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

chrysene (ISO)

clozapine (ISO)

coumarin (ISO)

Cuprizon (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

dioxygen (ISO)

diuron (EXP)

fenvalerate (EXP)

FR900359 (ISO)

isobutanol (ISO)

ivermectin (ISO)

methyl methanesulfonate (ISO)

paracetamol (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

rotenone (ISO)

sodium arsenite (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

tributylstannane (EXP)

triphenyl phosphate (ISO)

Triptolide (EXP)

tungsten (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

chromatin organization (IEA)

chromatin remodeling (IEA)

negative regulation of cell migration (IEA,ISO)

positive regulation of DNA-templated transcription (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

protein polyubiquitination (IEA,ISO)

protein ubiquitination (IEA)

regulation of DNA-templated transcription (IEA,ISO)

regulation of mitotic cell cycle (ISO)

ubiquitin-dependent protein catabolic process (IEA,ISO)

Cellular Component

HULC complex (IBA,IEA,ISO)

nucleolus (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,IEA,ISO)

ubiquitin ligase complex (IEA,ISO)

Molecular Function

chromatin binding (IEA,ISO)

histone binding (IEA,ISO)

histone H2B C-terminal K residue ubiquitin ligase activity (IEA,ISO)

identical protein binding (IEA,ISO)

metal ion binding (IEA)

mRNA 3'-UTR binding (IEA,ISO)

p53 binding (IEA,ISO)

protein binding (ISO)

transcription coactivator activity (IEA,ISO)

transferase activity (IEA)

ubiquitin protein ligase activity (IBA,IEA)

ubiquitin protein ligase binding (IEA,ISO)

ubiquitin-protein transferase activity (IEA,ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ataxia telangiectasia-mutated (ATM) signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation
6.	The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.	Shema E, etal., Genes Dev. 2008 Oct 1;22(19):2664-76. doi: 10.1101/gad.1703008.
7.	The ATM signaling network in development and disease.	Stracker TH, etal., Front Genet. 2013 Mar 25;4:37. doi: 10.3389/fgene.2013.00037. eCollection 2013.
8.	Proteomic analysis for human urinary proteins associated with arsenic intoxication.	Tan LB, etal., Proteomics Clin Appl. 2008 Jul;2(7-8):1087-98. doi: 10.1002/prca.200800021.
9.	Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia.	Wang E, etal., Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3901-6. doi: 10.1073/pnas.1301045110. Epub 2013 Feb 14.

Additional References at PubMed

PMID:16307923	PMID:16337599	PMID:16713563	PMID:19037095	PMID:19410543	PMID:19575011	PMID:22252316	PMID:30201771

Genomics

Comparative Map Data

Rnf20
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	68,771,507 - 68,797,240 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	68,771,535 - 68,797,240 (+)	Ensembl				GRCr8
mRatBN7.2	5	63,976,063 - 64,001,754 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	63,976,045 - 64,001,754 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	65,909,405 - 65,935,039 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	67,728,751 - 67,754,385 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	67,698,118 - 67,723,752 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	64,892,996 - 64,920,397 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	64,892,802 - 64,920,390 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	69,386,793 - 69,411,969 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	66,371,470 - 66,397,538 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	63,606,822 - 63,632,554 (-)	NCBI		Celera
RGSC_v3.1	5	66,376,582 - 66,402,649 (+)	NCBI
Cytogenetic Map	5	q22	NCBI

RNF20
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	101,533,853 - 101,563,344 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	101,533,853 - 101,563,344 (+)	Ensembl			hg38	GRCh38
GRCh37	9	104,296,135 - 104,325,626 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	103,335,954 - 103,365,447 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	101,375,687 - 101,405,180	NCBI
Celera	9	74,810,388 - 74,839,881 (+)	NCBI		Celera
Cytogenetic Map	9	q31.1	NCBI
HuRef	9	73,896,855 - 73,926,373 (+)	NCBI		HuRef
CHM1_1	9	104,442,536 - 104,472,031 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	113,708,604 - 113,738,115 (+)	NCBI		T2T-CHM13v2.0

Rnf20
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	49,632,005 - 49,656,887 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	49,632,006 - 49,656,887 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	49,632,005 - 49,656,887 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	49,632,006 - 49,656,887 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	49,644,932 - 49,669,758 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	49,653,221 - 49,677,986 (+)	NCBI		MGSCv36	mm8
Celera	4	49,660,371 - 49,685,183 (+)	NCBI		Celera
Cytogenetic Map	4	B1	NCBI
cM Map	4	26.69	NCBI

Rnf20
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	24,273,714 - 24,299,460 (-)	Ensembl
ChiLan1.0	NW_004955419	24,273,714 - 24,299,454 (-)	NCBI	ChiLan1.0	ChiLan1.0

RNF20
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	37,803,704 - 37,833,529 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	37,806,076 - 37,835,885 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	72,738,132 - 72,767,868 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	100,732,240 - 100,761,725 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	100,732,342 - 100,761,258 (+)	Ensembl			panPan2	panpan1.1

RNF20
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	58,239,245 - 58,266,637 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	58,239,313 - 58,265,866 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	56,683,443 - 56,711,138 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	59,374,518 - 59,402,216 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	59,374,614 - 59,402,209 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	57,884,293 - 57,911,989 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	57,897,263 - 57,924,945 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	58,594,981 - 58,622,677 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rnf20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	173,142,982 - 173,168,000 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936524	9,690,566 - 9,717,173 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936524	9,690,611 - 9,715,579 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF20
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	243,225,924 - 243,254,446 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	243,225,711 - 243,254,465 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	271,840,799 - 271,868,934 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNF20
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	37,872,953 - 37,901,421 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	37,872,578 - 37,899,864 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666035	4,599,037 - 4,684,170 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnf20
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	9,758,101 - 9,783,411 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624758	9,759,535 - 9,783,235 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rnf20
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	57,240,949 - 57,266,225 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rnf20
249 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	661
Count of miRNA genes:	274
Interacting mature miRNAs:	342
Transcripts:	ENSRNOT00000059869
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	32751649	77751649	Rat
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	38011670	83011670	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	52665372	94894052	Rat
6907115	Mcs29	Mammary carcinoma susceptibility QTL 29			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	38004331	83004331	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	23671493	79046465	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
61386	Bp49	Blood pressure QTL 49	16.6		cerebrum integrity trait (VT:0010549)	brain infarction volume (CMO:0001013)	5	65089051	103648916	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	48523123	134369373	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	38011670	83011670	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	38011670	83011670	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
1331782	Rf36	Renal function QTL 36	3.296		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	39019942	102105896	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	33311673	78311673	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	32751649	77751649	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	39985948	84985948	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	6922282	81330203	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33311673	78311673	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	39526924	84526924	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	48523123	91770353	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	60601597	137492949	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	91770353	Rat
61359	Eaex	Experimental allergic encephalomyelitis QTL x	3		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	5	60511627	105511627	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	7065535	74335773	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	64589016	109589016	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	87027358	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	26023211	71023211	Rat
2316954	Rf57	Renal function QTL 57	0		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	64589016	93503770	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	56546393	101546393	Rat
2316957	Pur21	Proteinuria QTL 21	6.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	5	64589016	91762830	Rat

Markers in Region

BF397033

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	68,790,685 - 68,790,993 (+)	Marker Load Pipeline
mRatBN7.2	5	63,995,199 - 63,995,507 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	64,913,843 - 64,914,150	NCBI	Rnor6.0
Rnor_5.0	5	69,405,415 - 69,405,722	UniSTS	Rnor5.0
RGSC_v3.4	5	66,390,984 - 66,391,291	UniSTS	RGSC3.4
Celera	5	63,613,068 - 63,613,375	UniSTS
RH 3.4 Map	5	433.0	UniSTS
Cytogenetic Map	5	q22	UniSTS

MARC_15327-15328:1017321397:1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	63,994,720 - 63,995,518 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	64,913,364 - 64,914,161	NCBI	Rnor6.0
Rnor_5.0	5	69,404,936 - 69,405,733	UniSTS	Rnor5.0
RGSC_v3.4	5	66,390,505 - 66,391,302	UniSTS	RGSC3.4
Celera	5	63,613,057 - 63,613,854	UniSTS
Cytogenetic Map	5	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001436768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238154	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000059869 ⟹ ENSRNOP00000056614

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	68,771,535 - 68,797,240 (+)	Ensembl
mRatBN7.2 Ensembl	5	63,976,127 - 64,001,754 (+)	Ensembl
Rnor_6.0 Ensembl	5	64,892,802 - 64,920,390 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096159 ⟹ ENSRNOP00000094446

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	68,776,889 - 68,797,240 (+)	Ensembl
mRatBN7.2 Ensembl	5	63,981,222 - 64,001,754 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105438 ⟹ ENSRNOP00000088402

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	63,976,045 - 64,000,555 (+)	Ensembl

RefSeq Acc Id:

NM_001107929 ⟹ NP_001101399

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	68,771,615 - 68,797,240 (+)	NCBI
mRatBN7.2	5	63,976,127 - 64,001,754 (+)	NCBI
Rnor_6.0	5	64,893,077 - 64,920,397 (+)	NCBI
Rnor_5.0	5	69,386,793 - 69,411,969 (+)	NCBI
RGSC_v3.4	5	66,371,470 - 66,397,538 (+)	RGD
Celera	5	63,606,822 - 63,632,554 (-)	RGD

Sequence:

show sequence

AATCCCTCTTGGAGCAGGTCCGAAATGAGGGATTGAATCCCGCACCGCCCTTCGTAAATAACCC
CTGGAAGCTGCGCGCCCGCGGCGGGAGTTGCTAGAGCCCAGGTTTGCTCTGTTGTCCGGTGCTC
CTGGGCCCTGAGTGGCGAGGTCCCATCTTCCCGGCCTGTGGCTTGCCACGCCGGAGGTTGCGGC
CAGCGCTTTCCATTCAAGTTGCGCTCCCTCCTCATCTCTTGTTTCCTCTCTTTCCAGGCGAGAT
CCAACTCAGATTGCTGCTTGCCATAGGTTCCTTGTCCTGGAGTTTGAATTGGAAGCCGGCGGGG
TGTAGACTCGTGATGGTCGCGTTTCTCGCGATCTAGCATCCATTCCTCCTCCTTTAAGCATCGG
AACCAGTCAGAAAAAATAGCTGTCATCTTATACCAAGATGTCAGGGATTGGAAATAAAAGAGCG
GCTGGAGAGCCAGGCACATCTGTGCCCCCAGAGAAGAAGACAGCTGTCGAAGATTCAGGGACCA
CAGTGGAAACAATTAAACTAGGAGGTGTCTCTTCAACGGAGGAATTAGACATTCGAACACTGCA
ATCGAAAAATCGTAAGCTAGCAGAAATGCTAGATCAGCGGCAGGCCATTGAAGATGAGCTTCGG
GAGCACATTGAGAAGCTGGAGCGACGCCAGGCCACCGACGATGCCTCACTGTTGATCGTGAACC
GGTACTGGAGCCAGTTTGATGAAAACATCCGCATCATCCTTAAACGTTATGATCTGGACCAGGG
TTTGGGAGACCTACTCACAGAAAGGAAAGCCTTGGTTGTGCCAGAGCCTGAGCCCGACTCTGAC
AGTAATCAGGAGCGCAAAGATGACCGTGAGAGAGGGGAAGGGCAAGAGCCAGCTTTCTCTTTCC
TTGCTACTTTGGCTAGCAGTTCCAGTGAGGAGATGGAGTCCCAGCTTCAGGAGCGCGTGGAGTC
CTCCCGCCGTGCTGTGTCTCAGATTGTGACCGTCTATGATAAATTGCAAGAAAAAGTGGATCTC
TTGTCCCGGAAACTGAACAGTGGAGATAACCTGATAATGGAGGAAGCAGTACAGGAGCTGAACT
CCTTCCTTGCGCAAGAGAATGTGAGGCTCCAGGAACTGACAGATCTCCTTCAGGAGAAGCATCA
CACCATGTCTCAGGAGTTCTGTAAGCTGCAGGGTAAAGTAGAGACAGCAGAGTCACGAGTGTCC
GTCTTGGAGTCCATGATTGATGACCTGCAGTGGGATATTGACAAAATTCGAAAAAGAGAACAGC
GGCTCAACCGGCATTTGGCTGAAGTCCTAGAGCGGGTGAACTCAAAAGGCTATAAAGTGTACGG
AGCAGGGAGCAGTCTCTATGGAGGCACAATCACCATCAATGCCCGGAAGTTTGAGGAAATGAAT
GCTGAGCTTGAGGAGAACAAAGAGTTGGCTCAGAACCGACATTGTGAGCTAGAGAAACTTCGTC
AAGACTTTGAAGAGGTCACTACACAGAATGAAAAGTTGAAGGTGGAGTTGCGGAGCGCAGTGGA
GGAAGTGGTTAAGGAAACCCCAGAATATCGCTGCATGCAGTCACAGTTCTCTGTCCTGTACAAT
GAGAGTCTACAGTTGAAAGCTCACTTGGATGAAGCTCGGACCCTGCTTCATGGCACCCGGGGAA
CTCACCAGCGCCAGGTTGAACTCATTGAGCGAGATGAGGTTAGTCTGCATAAGAAGCTGAGAAC
TGAAGTGATTCAGCTGGAGGATACCTTGGCCCAGGTCCGCAAGGAGTATGAGATGTTGAGGATA
GAGTTTGAGCAGACCCTTGCGGCCAATGAACAAGCAGGCCCCATAAACCGGGAGATGCGGCACC
TCATTAGCAGTCTCCAGAACCATAACCACCAGCTGAAGGGGGAGGTCCTGAGGTATAAGCGGAA
ACTCAGAGAGGCACAGTCTGACCTGAACAAGACGCGTCTGCGCAGTGGCAGTGCCCTCCTGCAG
TCGCAGTCTAGTACTGAGGACGCCAAGGATGAACCCACAGAGCTGAAGCAAGACTCTGAGGACC
TCGCCACTCATTCCTCAGCATTGAAGGCCTCTCAGGAGGATGAAGTGAAGTCTAAGCGGGATGA
GGAAGAGAGAGAACGAGAAAGGAGGGAGAAAGAAAGAGAGAGAGAACGAGAACGGGAAAAGGAA
AAGGAGAGAGAACGAGAGAAACAGAAACTGAAAGAGTCGGAAAAAGAGAGAGATCCTGTTAAGG
ATAAGGACAAAGGGAAGCACGATGACGGGAGGAAGAAGGAGGCAGAGATCATCAAGCAGCTGAA
GACTGAGCTCAAGAAAGCACAAGAGAGCCAGAAGGAGATGAAGCTGCTCCTGGACATGTACCGC
TCTGCCCCCAAGGAGCAGAGAGACAAAGTGCAGCTAATGGCGGCCGAGAAGAAGTCAAAGGCAG
AGTTGGAGGATCTCAGGCAAAGACTCAAGGATCTGGAAGATAAGGAGAAGAAGGAGAATAAGAA
AATGGCTGATGAGGACGCCTTGAGGAAGATCCGGGCAGTGGAAGAGCAGATCGAATACCTGCAG
AAGAAGCTGGCTGTGGCCAAGCAGGAGGAAGAAGCTCTCCTGTCTGAGATGGATGTCACAGGAC
AGGCCTTTGAGGACATGCAGGAGCAGAACATCCGTTTGATGCAGCAGTTGCGGGAGAAGGATGA
TGCAAACTTCAAGCTCATGTCAGAGCGGATCAAGTCTAATCAGATCCATAAGTTGCTTAAAGAG
GAAAAGGAAGAGTTAGCTGACCAGGTTTTGACACTGAAGACTCAGGTAGATGCCCAGTTACAGG
TAGTAAGAAAGCTGGAAGAGAAGGAGCACCTGCTTCAGAGTAACATTGGCACAGGGGAGAAGGA
GCTGGGTCTTAGGACTCAAGCCTTAGAGATGAATAAACGCAAGGCCATGGAGGCGGCCCAGCTT
GCAGATGACCTCAAAGCACAGCTGGAACTGGCTCAGAAGAAGCTCCATGATTTTCAGGATGAAA
TTGTGGAGAACAGTGTCACCAAGGAAAAGGACTTGTTCAATTTCAAACGCGCACAGGAAGACAT
CTCTAGGCTCCGAAGAAAGCTGGAGACAACCAAGAAGCCAGACAACGTGCCCAAATGTGACGAG
ATTCTGATGGAGGAGATAAAGGACTACAAGGCGCGGCTGACCTGCCCTTGCTGTAACATGCGTA
AAAAGGATGCAGTACTTACCAAGTGTTTTCACGTTTTCTGCTTTGAGTGTGTGAAGACGCGCTA
TGACACTCGCCAGCGCAAGTGTCCCAAGTGTAACGCTGCTTTCGGTGCCAATGATTTCCATCGC
ATCTACATTGGCTGAGTGCAGTCAAGAGAGAGAACTGGCTAGGCAAGCACTTACTCATCAGTCA
CCAGGCCTCTACCTCTCCCTCTGTGACAGCTGGCCGGCTCCCTGCTCCCCGGACTGTCCAGGTT
CTCTTCGCCAGTAGCCAGAGAACATTCGTGAAAAAGACTGCAAGTCTTGGGGTTTAGAATGAAC
TAGAAGCTACTAGTGTTTGTCTTCCTATCAGCTTTCTTTATGTCCTTTCAGAGTTTTCAGCATT
TTCTTCTTGGGCAAAGCCTGTAAACTTGGATTTACCCATCCTCCTGAAGAAGTCAGGTTGATGG
TTTTGACACTGAGAAGGGAATGTCATAGAGTGAACATATACTATTATGGAGTAGTGAACTTTTA
GAAATAAGCTATCGATGGGCCCCAAATTCTTGATTTGGTAATAAACCTTTCTAAACTTAGGTTG
TAAAATGGTATAATTGTGATAGTCTCTCCTGGAAGGTTCGAAGCCTTAATGAAATTATATCCAG
GATAAGTCTATCTCTCATTTCTAGTAAACTGACTTTTTGGGTCAGTTGGACTTCTTGCTAAAGT
TATTTATGTTTTAAGTATTCAAATATTAATAGGTTTTTTTTTTTAATTTCTTAAGGCCAGAATG
ATTTCAAACATGATAGTTCCTATGGTTTTGCTTTTTGTTTTTTTCCTCCTGAAATCAGACTTAG
TACTTAAGAAGCAGCAGGAATGGATTATGAAGAGATCTAGGTAGTCTAGGATAAGATCCAGAGA
GGGTTGGTGAATTATGAATTACTGTCATCATCCTCTCAGAGGGACTCTTTGATTTCTGTTTTCC
AGAAGATTCTCAGTAATGTTTCTGTAGGATTTTAATATTCCATATACTTTCAATTAAAGCAGGA
TTCAGCTTTC

hide sequence

RefSeq Acc Id:

XM_006238154 ⟹ XP_006238216

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	68,771,507 - 68,797,240 (+)	NCBI
mRatBN7.2	5	63,976,065 - 64,001,754 (+)	NCBI
Rnor_6.0	5	64,892,996 - 64,920,397 (+)	NCBI
Rnor_5.0	5	69,386,793 - 69,411,969 (+)	NCBI

Sequence:

show sequence

TGCAGTGTATGGGACGAAGTTGAAGCAACTTCCTTTTCTTTTTCCCTACTTCCTCTCCCTGCCT
CCGCCTCCGTGAAGCTCAATCCCTCTTGGAGCAGGTCCGAAATGAGGGATTGAATCCCGCACCG
CCCTTCGTAAATAACCCCTGGAAGCTGCGCGCCCGCGGCGGGAGTTGCTAGAGCCCAGGCGAGA
TCCAACTCAGATTGCTGCTTGCCATAGGTTCCTTGTCCTGGAGTTTGAATTGGAAGCCGGCGGG
GTGTAGACTCGTGATGGTCGCGTTTCTCGCGATCTAGCATCCATTCCTCCTCCTTTAAGCATCG
GAACCAGTCAGAAAAAATAGCTGTCATCTTATACCAAGATGTCAGGGATTGGAAATAAAAGAGC
GGCTGGAGAGCCAGGCACATCTGTGCCCCCAGAGAAGAAGACAGCTGTCGAAGATTCAGGGACC
ACAGTGGAAACAATTAAACTAGGAGGTGTCTCTTCAACGGAGGAATTAGACATTCGAACACTGC
AATCGAAAAATCGTAAGCTAGCAGAAATGCTAGATCAGCGGCAGGCCATTGAAGATGAGCTTCG
GGAGCACATTGAGAAGCTGGAGCGACGCCAGGCCACCGACGATGCCTCACTGTTGATCGTGAAC
CGGTACTGGAGCCAGTTTGATGAAAACATCCGCATCATCCTTAAACGTTATGATCTGGACCAGG
GTTTGGGAGACCTACTCACAGAAAGGAAAGCCTTGGTTGTGCCAGAGCCTGAGCCCGACTCTGA
CAGTAATCAGGAGCGCAAAGATGACCGTGAGAGAGGGGAAGGGCAAGAGCCAGCTTTCTCTTTC
CTTGCTACTTTGGCTAGCAGTTCCAGTGAGGAGATGGAGTCCCAGCTTCAGGAGCGCGTGGAGT
CCTCCCGCCGTGCTGTGTCTCAGATTGTGACCGTCTATGATAAATTGCAAGAAAAAGTGGATCT
CTTGTCCCGGAAACTGAACAGTGGAGATAACCTGATAATGGAGGAAGCAGTACAGGAGCTGAAC
TCCTTCCTTGCGCAAGAGAATGTGAGGCTCCAGGAACTGACAGATCTCCTTCAGGAGAAGCATC
ACACCATGTCTCAGGAGTTCTGTAAGCTGCAGGGTAAAGTAGAGACAGCAGAGTCACGAGTGTC
CGTCTTGGAGTCCATGATTGATGACCTGCAGTGGGATATTGACAAAATTCGAAAAAGAGAACAG
CGGCTCAACCGGCATTTGGCTGAAGTCCTAGAGCGGGTGAACTCAAAAGGCTATAAAGTGTACG
GAGCAGGGAGCAGTCTCTATGGAGGCACAATCACCATCAATGCCCGGAAGTTTGAGGAAATGAA
TGCTGAGCTTGAGGAGAACAAAGAGTTGGCTCAGAACCGACATTGTGAGCTAGAGAAACTTCGT
CAAGACTTTGAAGAGGTCACTACACAGAATGAAAAGTTGAAGGTGGAGTTGCGGAGCGCAGTGG
AGGAAGTGGTTAAGGAAACCCCAGAATATCGCTGCATGCAGTCACAGTTCTCTGTCCTGTACAA
TGAGAGTCTACAGTTGAAAGCTCACTTGGATGAAGCTCGGACCCTGCTTCATGGCACCCGGGGA
ACTCACCAGCGCCAGGTTGAACTCATTGAGCGAGATGAGGTTAGTCTGCATAAGAAGCTGAGAA
CTGAAGTGATTCAGCTGGAGGATACCTTGGCCCAGGTCCGCAAGGAGTATGAGATGTTGAGGAT
AGAGTTTGAGCAGACCCTTGCGGCCAATGAACAAGCAGGCCCCATAAACCGGGAGATGCGGCAC
CTCATTAGCAGTCTCCAGAACCATAACCACCAGCTGAAGGGGGAGGTCCTGAGGTATAAGCGGA
AACTCAGAGAGGCACAGTCTGACCTGAACAAGACGCGTCTGCGCAGTGGCAGTGCCCTCCTGCA
GTCGCAGTCTAGTACTGAGGACGCCAAGGATGAACCCACAGAGCTGAAGCAAGACTCTGAGGAC
CTCGCCACTCATTCCTCAGCATTGAAGGCCTCTCAGGAGGATGAAGTGAAGTCTAAGCGGGATG
AGGAAGAGAGAGAACGAGAAAGGAGGGAGAAAGAAAGAGAGAGAGAACGAGAACGGGAAAAGGA
AAAGGAGAGAGAACGAGAGAAACAGAAACTGAAAGAGTCGGAAAAAGAGAGAGATCCTGTTAAG
GATAAGGACAAAGGGAAGCACGATGACGGGAGGAAGAAGGAGGCAGAGATCATCAAGCAGCTGA
AGACTGAGCTCAAGAAAGCACAAGAGAGCCAGAAGGAGATGAAGCTGCTCCTGGACATGTACCG
CTCTGCCCCCAAGGAGCAGAGAGACAAAGTGCAGCTAATGGCGGCCGAGAAGAAGTCAAAGGCA
GAGTTGGAGGATCTCAGGCAAAGACTCAAGGATCTGGAAGATAAGGAGAAGAAGGAGAATAAGA
AAATGGCTGATGAGGACGCCTTGAGGAAGATCCGGGCAGTGGAAGAGCAGATCGAATACCTGCA
GAAGAAGCTGGCTGTGGCCAAGCAGGAGGAAGAAGCTCTCCTGTCTGAGATGGATGTCACAGGA
CAGGCCTTTGAGGACATGCAGGAGCAGAACATCCGTTTGATGCAGCAGTTGCGGGAGAAGGATG
ATGCAAACTTCAAGCTCATGTCAGAGCGGATCAAGTCTAATCAGATCCATAAGTTGCTTAAAGA
GGAAAAGGAAGAGTTAGCTGACCAGGTTTTGACACTGAAGACTCAGGTAGATGCCCAGTTACAG
GTAGTAAGAAAGCTGGAAGAGAAGGAGCACCTGCTTCAGAGTAACATTGGCACAGGGGAGAAGG
AGCTGGGTCTTAGGACTCAAGCCTTAGAGATGAATAAACGCAAGGCCATGGAGGCGGCCCAGCT
TGCAGATGACCTCAAAGCACAGCTGGAACTGGCTCAGAAGAAGCTCCATGATTTTCAGGATGAA
ATTGTGGAGAACAGTGTCACCAAGGAAAAGGACTTGTTCAATTTCAAACGCGCACAGGAAGACA
TCTCTAGGCTCCGAAGAAAGCTGGAGACAACCAAGAAGCCAGACAACGTGCCCAAATGTGACGA
GATTCTGATGGAGGAGATAAAGGACTACAAGGCGCGGCTGACCTGCCCTTGCTGTAACATGCGT
AAAAAGGATGCAGTACTTACCAAGTGTTTTCACGTTTTCTGCTTTGAGTGTGTGAAGACGCGCT
ATGACACTCGCCAGCGCAAGTGTCCCAAGTGTAACGCTGCTTTCGGTGCCAATGATTTCCATCG
CATCTACATTGGCTGAGTGCAGTCAAGAGAGAGAACTGGCTAGGCAAGCACTTACTCATCAGTC
ACCAGGCCTCTACCTCTCCCTCTGTGACAGCTGGCCGGCTCCCTGCTCCCCGGACTGTCCAGGT
TCTCTTCGCCAGTAGCCAGAGAACATTCGTGAAAAAGACTGCAAGTCTTGGGGTTTAGAATGAA
CTAGAAGCTACTAGTGTTTGTCTTCCTATCAGCTTTCTTTATGTCCTTTCAGAGTTTTCAGCAT
TTTCTTCTTGGGCAAAGCCTGTAAACTTGGATTTACCCATCCTCCTGAAGAAGTCAGGTTGATG
GTTTTGACACTGAGAAGGGAATGTCATAGAGTGAACATATACTATTATGGAGTAGTGAACTTTT
AGAAATAAGCTATCGATGGGCCCCAAATTCTTGATTTGGTAATAAACCTTTCTAAACTTAGGTT
GTAAAATGGTATAATTGTGATAGTCTCTCCTGGAAGGTTCGAAGCCTTAATGAAATTATATCCA
GGATAAGTCTATCTCTCATTTCTAGTAAACTGACTTTTTGGGTCAGTTGGACTTCTTGCTAAAG
TTATTTATGTTTTAAGTATTCAAATATTAATAGGTTTTTTTTTTTAATTTCTTAAGGCCAGAAT
GATTTCAAACATGATAGTTCCTATGGTTTTGCTTTTTGTTTTTTTCCTCCTGAAATCAGACTTA
GTACTTAAGAAGCAGCAGGAATGGATTATGAAGAGATCTAGGTAGTCTAGGATAAGATCCAGAG
AGGGTTGGTGAATTATGAATTACTGTCATCATCCTCTCAGAGGGACTCTTTGATTTCTGTTTTC
CAGAAGATTCTCAGTAATGTTTCTGTAGGATTTTAATATTCCATATACTTTCAATTAAAGCAGG
ATTCAGCTTTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001101399	(Get FASTA)	NCBI Sequence Viewer
	NP_001423697	(Get FASTA)	NCBI Sequence Viewer
	XP_006238216	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL78174	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000056614
	ENSRNOP00000056614.2
	ENSRNOP00000094446
	ENSRNOP00000094446.1

RefSeq Acc Id:

NP_001101399 ⟸ NM_001107929

- UniProtKB:

D3ZYQ9 (UniProtKB/TrEMBL), A0A8I6AJL7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSGIGNKRAAGEPGTSVPPEKKTAVEDSGTTVETIKLGGVSSTEELDIRTLQSKNRKLAEMLDQ
RQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDLDQGLGDLLTERKALV
VPEPEPDSDSNQERKDDRERGEGQEPAFSFLATLASSSSEEMESQLQERVESSRRAVSQIVTVY
DKLQEKVDLLSRKLNSGDNLIMEEAVQELNSFLAQENVRLQELTDLLQEKHHTMSQEFCKLQGK
VETAESRVSVLESMIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITI
NARKFEEMNAELEENKELAQNRHCELEKLRQDFEEVTTQNEKLKVELRSAVEEVVKETPEYRCM
QSQFSVLYNESLQLKAHLDEARTLLHGTRGTHQRQVELIERDEVSLHKKLRTEVIQLEDTLAQV
RKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTR
LRSGSALLQSQSSTEDAKDEPTELKQDSEDLATHSSALKASQEDEVKSKRDEEERERERREKER
EREREREKEKEREREKQKLKESEKERDPVKDKDKGKHDDGRKKEAEIIKQLKTELKKAQESQKE
MKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRA
VEEQIEYLQKKLAVAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKS
NQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRTQALEMNK
RKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDLFNFKRAQEDISRLRRKLETTKK
PDNVPKCDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNA
AFGANDFHRIYIG

hide sequence

RefSeq Acc Id:

XP_006238216 ⟸ XM_006238154

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSGIGNKRAAGEPGTSVPPEKKTAVEDSGTTVETIKLGGVSSTEELDIRTLQSKNRKLAEMLDQ
RQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDLDQGLGDLLTERKALV
VPEPEPDSDSNQERKDDRERGEGQEPAFSFLATLASSSSEEMESQLQERVESSRRAVSQIVTVY
DKLQEKVDLLSRKLNSGDNLIMEEAVQELNSFLAQENVRLQELTDLLQEKHHTMSQEFCKLQGK
VETAESRVSVLESMIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITI
NARKFEEMNAELEENKELAQNRHCELEKLRQDFEEVTTQNEKLKVELRSAVEEVVKETPEYRCM
QSQFSVLYNESLQLKAHLDEARTLLHGTRGTHQRQVELIERDEVSLHKKLRTEVIQLEDTLAQV
RKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTR
LRSGSALLQSQSSTEDAKDEPTELKQDSEDLATHSSALKASQEDEVKSKRDEEERERERREKER
EREREREKEKEREREKQKLKESEKERDPVKDKDKGKHDDGRKKEAEIIKQLKTELKKAQESQKE
MKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRA
VEEQIEYLQKKLAVAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKS
NQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRTQALEMNK
RKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDLFNFKRAQEDISRLRRKLETTKK
PDNVPKCDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNA
AFGANDFHRIYIG

hide sequence

Ensembl Acc Id:

ENSRNOP00000056614 ⟸ ENSRNOT00000059869

Ensembl Acc Id:

ENSRNOP00000088402 ⟸ ENSRNOT00000105438

Ensembl Acc Id:

ENSRNOP00000094446 ⟸ ENSRNOT00000096159

Protein Domains

RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZYQ9-F1-model_v2	AlphaFold	D3ZYQ9	1-973	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693732

Promoter ID:

EPDNEW_R4257

Type:

initiation region

Name:

Rnf20_1

Description:

ring finger protein 20

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	64,893,048 - 64,893,108	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311936	AgrOrtholog
BioCyc Gene	G2FUF-41324	BioCyc
Ensembl Genes	ENSRNOG00000006087	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000059869	ENTREZGENE
	ENSRNOT00000059869.5	UniProtKB/TrEMBL
	ENSRNOT00000096159	ENTREZGENE
	ENSRNOT00000096159.2	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
InterPro	E3_ubiquit_lig_Bre1	UniProtKB/TrEMBL
	Znf_C3HC4_RING-type	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
KEGG Report	rno:313216	UniProtKB/TrEMBL
NCBI Gene	313216	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE BRE1A	UniProtKB/TrEMBL
	PTHR23163	UniProtKB/TrEMBL
Pfam	zf-C3HC4	UniProtKB/TrEMBL
PhenoGen	Rnf20	PhenoGen
PROSITE	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000006087	RatGTEx
SMART	RING	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
UniProt	A0A8I6AJL7	ENTREZGENE, UniProtKB/TrEMBL
	D3ZYQ9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-02	Rnf20	ring finger protein 20	Rnf20	ring finger protein 20, E3 ubiquitin protein ligase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-10-15	Rnf20	ring finger protein 20, E3 ubiquitin protein ligase	Rnf20	ring finger protein 20	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Rnf20	ring finger protein 20	Rnf20_predicted	ring finger protein 20 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Rnf20_predicted	ring finger protein 20 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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RGD Manual Annotations