Ddi2 (DDI proteasomal shuttling factor 2) - Rat Genome Database

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Pathways
Gene: Ddi2 (DDI proteasomal shuttling factor 2) Rattus norvegicus
Analyze
Symbol: Ddi2
Name: DDI proteasomal shuttling factor 2 (Ensembl:DNA damage inducible 1 homolog 2)
RGD ID: 1311815
Description: Predicted to enable aspartic-type endopeptidase activity; identical protein binding activity; and ubiquitin binding activity. Predicted to be involved in several processes, including cellular response to hydroxyurea; proteolysis; and regulation of DNA stability. Orthologous to human DDI2 (DNA damage inducible 1 homolog 2) and RSC1A1 (regulator of solute carriers 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; metformin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA damage inducible 1 homolog 2; DNA-damage inducible protein 2; LOC313668; protein DDI1 homolog 2; RGD1311815; similar to RIKEN cDNA 1700027M01
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85159,272,625 - 159,318,365 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5159,272,625 - 159,318,310 (-)EnsemblGRCr8
mRatBN7.25153,989,591 - 154,035,342 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,995,589 - 154,035,283 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5156,674,824 - 156,720,295 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05158,448,107 - 158,493,578 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05158,437,257 - 158,482,731 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05160,230,958 - 160,282,836 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,230,955 - 160,282,810 (-)Ensemblrn6Rnor6.0
Rnor_5.05163,945,355 - 163,995,230 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45160,582,315 - 160,621,531 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5152,349,276 - 152,388,832 (-)NCBICelera
RGSC_v3.15160,587,176 - 160,631,541 (-)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:27461074   PMID:27528193   PMID:27676298   PMID:29290612  


Genomics

Comparative Map Data
Ddi2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85159,272,625 - 159,318,365 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5159,272,625 - 159,318,310 (-)EnsemblGRCr8
mRatBN7.25153,989,591 - 154,035,342 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,995,589 - 154,035,283 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5156,674,824 - 156,720,295 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05158,448,107 - 158,493,578 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05158,437,257 - 158,482,731 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05160,230,958 - 160,282,836 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,230,955 - 160,282,810 (-)Ensemblrn6Rnor6.0
Rnor_5.05163,945,355 - 163,995,230 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45160,582,315 - 160,621,531 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5152,349,276 - 152,388,832 (-)NCBICelera
RGSC_v3.15160,587,176 - 160,631,541 (-)NCBI
Cytogenetic Map5q36NCBI
DDI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38115,617,458 - 15,669,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl115,617,458 - 15,669,044 (+)Ensemblhg38GRCh38
GRCh37115,943,953 - 15,995,539 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,816,657 - 15,859,335 (+)NCBIBuild 36Build 36hg18NCBI36
Celera114,426,817 - 14,470,431 (+)NCBICelera
Cytogenetic Map1p36.21NCBI
HuRef114,463,422 - 14,506,965 (+)NCBIHuRef
CHM1_1115,742,627 - 15,786,290 (+)NCBICHM1_1
T2T-CHM13v2.0115,062,171 - 15,113,775 (+)NCBIT2T-CHM13v2.0
Ddi2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,410,874 - 141,450,730 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4141,404,860 - 141,450,743 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384141,683,563 - 141,723,419 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,677,549 - 141,723,419 (-)Ensemblmm10GRCm38
MGSCv374141,239,478 - 141,279,334 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364140,955,639 - 140,995,495 (-)NCBIMGSCv36mm8
Celera4143,507,133 - 143,546,916 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map474.69NCBI
Ddi2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555272,493,469 - 2,534,768 (-)Ensembl
ChiLan1.0NW_0049555272,498,211 - 2,534,768 (-)NCBIChiLan1.0ChiLan1.0
DDI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21211,247,481 - 211,301,116 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11210,496,015 - 210,549,655 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0114,757,327 - 14,810,959 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1115,749,497 - 15,795,631 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl115,749,497 - 15,790,263 (+)EnsemblpanPan2panpan1.1
PanPan1.1 Ensembl115,793,469 - 15,795,325 (+)EnsemblpanPan2panpan1.1
DDI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,915,613 - 81,957,803 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,459,544 - 78,495,093 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0282,570,756 - 82,606,321 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl282,570,758 - 82,606,257 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1279,323,680 - 79,359,224 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0280,342,173 - 80,377,711 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0281,407,500 - 81,443,055 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
DDI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120116,640,166 - 116,680,403 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605420,167,661 - 20,222,435 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddi2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1116,428,745 - 16,462,251 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ddi2
168 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:838
Count of miRNA genes:320
Interacting mature miRNAs:414
Transcripts:ENSRNOT00000016352
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5149805999162987697Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5156396728167181764Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5149661912166600247Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5156289283171137955Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat

Markers in Region
AU040698  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25153,995,867 - 153,995,964 (+)MAPPERmRatBN7.2
Rnor_6.05160,237,230 - 160,237,326NCBIRnor6.0
Rnor_5.05163,951,630 - 163,951,726UniSTSRnor5.0
RGSC_v3.45160,582,594 - 160,582,690UniSTSRGSC3.4
Celera5152,349,555 - 152,349,651UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000016352   ⟹   ENSRNOP00000016352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5159,278,376 - 159,283,585 (-)Ensembl
mRatBN7.2 Ensembl5153,995,590 - 154,035,283 (-)Ensembl
Rnor_6.0 Ensembl5160,236,952 - 160,282,810 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076160   ⟹   ENSRNOP00000068216
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5160,230,955 - 160,282,810 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109253   ⟹   ENSRNOP00000087348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5159,277,949 - 159,310,051 (-)Ensembl
mRatBN7.2 Ensembl5153,995,589 - 154,027,085 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119479   ⟹   ENSRNOP00000077256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5159,277,949 - 159,318,310 (-)Ensembl
mRatBN7.2 Ensembl5153,995,589 - 154,035,283 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000125439   ⟹   ENSRNOP00000111109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5159,272,625 - 159,286,746 (-)Ensembl
RefSeq Acc Id: NM_001395586   ⟹   NP_001382515
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,272,625 - 159,318,310 (-)NCBI
mRatBN7.25153,989,591 - 154,035,283 (-)NCBI
RefSeq Acc Id: XM_006239305   ⟹   XP_006239367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,272,630 - 159,318,365 (-)NCBI
mRatBN7.25153,989,596 - 154,035,342 (-)NCBI
Rnor_6.05160,230,958 - 160,282,836 (-)NCBI
Rnor_5.05163,945,355 - 163,995,230 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239306   ⟹   XP_006239368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,272,630 - 159,310,608 (-)NCBI
mRatBN7.25153,989,596 - 154,027,586 (-)NCBI
Rnor_6.05160,230,958 - 160,275,140 (-)NCBI
Rnor_5.05163,945,355 - 163,995,230 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239308   ⟹   XP_006239370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,272,630 - 159,283,572 (-)NCBI
mRatBN7.25153,989,596 - 154,000,536 (-)NCBI
Rnor_6.05160,230,958 - 160,242,383 (-)NCBI
Rnor_5.05163,945,355 - 163,995,230 (-)NCBI
Sequence:
RefSeq Acc Id: XP_006239367   ⟸   XM_006239305
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y0Y2 (UniProtKB/TrEMBL),   A0A8I6GFW9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239368   ⟸   XM_006239306
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GFW9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239370   ⟸   XM_006239308
- Peptide Label: isoform X3
- UniProtKB: A6ITV4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016352   ⟸   ENSRNOT00000016352
Ensembl Acc Id: ENSRNOP00000068216   ⟸   ENSRNOT00000076160
Ensembl Acc Id: ENSRNOP00000077256   ⟸   ENSRNOT00000119479
Ensembl Acc Id: ENSRNOP00000087348   ⟸   ENSRNOT00000109253
RefSeq Acc Id: NP_001382515   ⟸   NM_001395586
- UniProtKB: A0A8J8Y1M0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111109   ⟸   ENSRNOT00000125439
Protein Domains
UBA   Ubiquitin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A096MJP9-F1-model_v2 AlphaFold A0A096MJP9 1-986 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694231
Promoter ID:EPDNEW_R4756
Type:multiple initiation site
Name:Ddi2_1
Description:DNA damage inducible 1 homolog 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05160,282,836 - 160,282,896EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311815 AgrOrtholog
BioCyc Gene G2FUF-39334 BioCyc
Ensembl Genes ENSRNOG00000012274 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016352 ENTREZGENE
  ENSRNOT00000016352.8 UniProtKB/TrEMBL
  ENSRNOT00000109253 ENTREZGENE
  ENSRNOT00000109253.2 UniProtKB/TrEMBL
  ENSRNOT00000119479 ENTREZGENE
  ENSRNOT00000119479.2 UniProtKB/TrEMBL
  ENSRNOT00000125439.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.70.10 UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7442573 IMAGE-MGC_LOAD
InterPro Ddi1/2_HDD UniProtKB/TrEMBL
  DDI1_N UniProtKB/TrEMBL
  Peptidase_aspartic UniProtKB/TrEMBL
  Peptidase_aspartic_euk-pred UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
  Ubiquitin UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
MGC_CLONE MGC:114394 IMAGE-MGC_LOAD
NCBI Gene 313668 ENTREZGENE
PANTHER DNA DAMAGE-INDUCIBLE 1 HOMOLOG 2 UniProtKB/TrEMBL
  SODIUM-GLUCOSE COTRANSPORTER REGULATORY PROTEIN -RELATED UniProtKB/TrEMBL
Pfam Asp_protease UniProtKB/TrEMBL
  Ddi2_HDD UniProtKB/TrEMBL
  ubiquitin UniProtKB/TrEMBL
PhenoGen Ddi2 PhenoGen
PROSITE UBA UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012274 RatGTEx
SMART UBA UniProtKB/TrEMBL
Superfamily-SCOP Pept_Aspartic UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A8I5Y0Y2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GFW9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8Y1M0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M6X4_RAT UniProtKB/TrEMBL
  A6ITV4 ENTREZGENE, UniProtKB/TrEMBL
  Q4V8J5_RAT UniProtKB/TrEMBL
UniProt Secondary F1MAK5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Ddi2  DDI proteasomal shuttling factor 2  Ddi2  DNA damage inducible 1 homolog 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-03-02 Ddi2  DNA damage inducible 1 homolog 2  Ddi2  DNA-damage inducible protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-15 Ddi2  DNA-damage inducible protein 2  RGD1311815  similar to RIKEN cDNA 1700027M01  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1311815  similar to RIKEN cDNA 1700027M01  RGD1311815_predicted  similar to RIKEN cDNA 1700027M01 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311815_predicted  similar to RIKEN cDNA 1700027M01 (predicted)  LOC313668_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313668_predicted  similar to RIKEN cDNA 1700027M01 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL