Sox18 (SRY-box transcription factor 18) - Rat Genome Database

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Gene: Sox18 (SRY-box transcription factor 18) Rattus norvegicus
Analyze
Symbol: Sox18
Name: SRY-box transcription factor 18
RGD ID: 1311718
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including establishment of endothelial barrier; regulation of transcription by RNA polymerase II; and vasculature development. Predicted to act upstream of or within several processes, including circulatory system development; regulation of DNA-templated transcription; and stem cell fate specification. Predicted to be located in chromatin. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in hypotrichosis-lymphedema-telangiectasia syndrome and hypotrichosis-lymphedema-telangiectasia-renal defect syndrome. Orthologous to human SOX18 (SRY-box transcription factor 18); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC311723; SRY (sex determining region Y)-box 18; SRY box 18; SRY-box containing gene 18; transcription factor SOX-18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83189,163,000 - 189,164,802 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3189,163,002 - 189,164,802 (-)EnsemblGRCr8
mRatBN7.23168,785,488 - 168,787,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,785,490 - 168,787,290 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3173,164,968 - 173,166,742 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03182,124,059 - 182,125,833 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,786,438 - 178,788,234 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03177,177,237 - 177,179,039 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3177,177,310 - 177,179,127 (-)Ensemblrn6Rnor6.0
Rnor_5.03180,885,768 - 180,887,570 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43170,820,460 - 170,822,262 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3163,800,470 - 163,802,272 (+)NCBICelera
RGSC_v3.13170,726,497 - 170,728,298 (-)NCBI
Cytogenetic Map3q43NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
folic acid  (ISO)
glycidol  (EXP)
graphite  (EXP)
GW 4064  (ISO)
hesperetin  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
iron dichloride  (ISO)
kenpaullone  (EXP)
L-methionine  (ISO)
lead diacetate  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
methamphetamine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nickel dichloride  (ISO)
nicotine  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
oxybenzone  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (ISO)
phosgene  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SCH 23390  (EXP)
silicon dioxide  (EXP)
Soman  (EXP)
sulfadimethoxine  (EXP)
temozolomide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
trichloroethene  (EXP,ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
transcription regulator complex  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. Irrthum A, etal., Am J Hum Genet. 2003 Jun;72(6):1470-8. Epub 2003 May 8.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:291594   PMID:7651823   PMID:10742113   PMID:11094083   PMID:11179689   PMID:11554755   PMID:12446692   PMID:12477932   PMID:14634005   PMID:16882943   PMID:16895968   PMID:16895970  
PMID:17610846   PMID:18065521   PMID:18931657   PMID:19429912   PMID:19515696   PMID:20228271   PMID:22292085   PMID:22344693  


Genomics

Comparative Map Data
Sox18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83189,163,000 - 189,164,802 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3189,163,002 - 189,164,802 (-)EnsemblGRCr8
mRatBN7.23168,785,488 - 168,787,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,785,490 - 168,787,290 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3173,164,968 - 173,166,742 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03182,124,059 - 182,125,833 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,786,438 - 178,788,234 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03177,177,237 - 177,179,039 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3177,177,310 - 177,179,127 (-)Ensemblrn6Rnor6.0
Rnor_5.03180,885,768 - 180,887,570 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43170,820,460 - 170,822,262 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3163,800,470 - 163,802,272 (+)NCBICelera
RGSC_v3.13170,726,497 - 170,728,298 (-)NCBI
Cytogenetic Map3q43NCBI
SOX18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382064,047,582 - 64,049,639 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2064,047,582 - 64,049,639 (-)Ensemblhg38GRCh38
GRCh372062,678,935 - 62,680,992 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362062,149,523 - 62,151,423 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342062,149,524 - 62,151,423NCBI
Celera2059,365,185 - 59,367,085 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2059,413,178 - 59,414,764 (-)NCBIHuRef
CHM1_12062,580,086 - 62,582,001 (-)NCBICHM1_1
T2T-CHM13v2.02065,867,606 - 65,869,664 (-)NCBIT2T-CHM13v2.0
Sox18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392181,311,630 - 181,313,433 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2181,311,629 - 181,313,433 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382181,669,837 - 181,671,640 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2181,669,836 - 181,671,640 (-)Ensemblmm10GRCm38
MGSCv372181,404,542 - 181,406,345 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362181,599,249 - 181,601,015 (-)NCBIMGSCv36mm8
Celera2185,752,229 - 185,754,032 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2103.71NCBI
Sox18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955528204,729 - 206,772 (+)NCBIChiLan1.0ChiLan1.0
SOX18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22169,865,334 - 69,867,256 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12069,857,345 - 69,859,266 (-)NCBINHGRI_mPanPan1
SOX18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12447,494,581 - 47,496,563 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2447,494,902 - 47,496,970 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2446,628,401 - 46,630,374 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02448,633,494 - 48,635,467 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2448,633,492 - 48,635,406 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12447,478,102 - 47,480,075 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02447,602,566 - 47,604,541 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02448,341,512 - 48,343,485 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sox18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,777,684 - 195,779,662 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651411,231,305 - 11,233,337 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493651411,231,327 - 11,233,292 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOX18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,869,870 - 62,871,748 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11762,869,868 - 62,871,758 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SOX18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12195,418 - 197,221 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605047,629,355 - 47,631,408 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sox18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474129,679,091 - 29,681,049 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474129,679,274 - 29,681,069 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Sox18
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15158,768,529 - 158,770,769 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:55
Count of miRNA genes:44
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000021790
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3181611379189428310Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat

Markers in Region
D3Hmgc21  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,787,741 - 168,787,906 (+)MAPPERmRatBN7.2
Rnor_6.03177,179,491 - 177,179,652NCBIRnor6.0
Rnor_5.03180,888,022 - 180,888,183UniSTSRnor5.0
RGSC_v3.43170,822,714 - 170,822,875UniSTSRGSC3.4
Celera3163,799,857 - 163,800,018UniSTS
Cytogenetic Map3q43UniSTS
AI385749  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,785,620 - 168,785,734 (+)MAPPERmRatBN7.2
Rnor_6.03177,177,370 - 177,177,483NCBIRnor6.0
Rnor_5.03180,885,901 - 180,886,014UniSTSRnor5.0
RGSC_v3.43170,820,593 - 170,820,706UniSTSRGSC3.4
Celera3163,802,026 - 163,802,139UniSTS
Cytogenetic Map3q43UniSTS
UniSTS:471103  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83189,163,924 - 189,164,520 (+)Marker Load Pipeline
mRatBN7.23168,786,412 - 168,787,008 (+)MAPPERmRatBN7.2
Rnor_6.03177,178,162 - 177,178,757NCBIRnor6.0
Rnor_5.03180,886,693 - 180,887,288UniSTSRnor5.0
RGSC_v3.43170,821,385 - 170,821,980UniSTSRGSC3.4
Celera3163,800,752 - 163,801,347UniSTS
Cytogenetic Map3q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 154 91 90 59 38 59 6 302 138 11 129 81 92 31 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000021790   ⟹   ENSRNOP00000021790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3189,163,002 - 189,164,802 (-)Ensembl
mRatBN7.2 Ensembl3168,785,490 - 168,787,290 (-)Ensembl
Rnor_6.0 Ensembl3177,177,310 - 177,179,127 (-)Ensembl
RefSeq Acc Id: NM_001024781   ⟹   NP_001019952
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83189,163,000 - 189,164,802 (-)NCBI
mRatBN7.23168,785,488 - 168,787,290 (-)NCBI
Rnor_6.03177,177,237 - 177,179,039 (-)NCBI
Rnor_5.03180,885,768 - 180,887,570 (-)NCBI
RGSC_v3.43170,820,460 - 170,822,262 (-)RGD
Celera3163,800,470 - 163,802,272 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001019952 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH97973 (Get FASTA)   NCBI Sequence Viewer  
  EDL88692 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021790
  ENSRNOP00000021790.3
RefSeq Acc Id: NP_001019952   ⟸   NM_001024781
- UniProtKB: Q4V7E4 (UniProtKB/TrEMBL),   F7FNP9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021790   ⟸   ENSRNOT00000021790
Protein Domains
HMG box   Sox C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4V7E4-F1-model_v2 AlphaFold Q4V7E4 1-377 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692762
Promoter ID:EPDNEW_R3286
Type:multiple initiation site
Name:Sox18_1
Description:SRY box 18
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03177,179,050 - 177,179,110EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311718 AgrOrtholog
BioCyc Gene G2FUF-46266 BioCyc
Ensembl Genes ENSRNOG00000016248 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021790 ENTREZGENE
  ENSRNOT00000021790.7 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7442067 IMAGE-MGC_LOAD
InterPro DUF3547 UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
  HMG_superfamily UniProtKB/TrEMBL
  Sox7/17/18_central UniProtKB/TrEMBL
  SRY-related_HMG-box_TFs UniProtKB/TrEMBL
KEGG Report rno:311723 UniProtKB/TrEMBL
MGC_CLONE MGC:116103 IMAGE-MGC_LOAD
NCBI Gene 311723 ENTREZGENE
PANTHER SOX TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR SOX-18 UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/TrEMBL
  Sox_C_TAD UniProtKB/TrEMBL
PhenoGen Sox18 PhenoGen
PROSITE HMG_BOX_2 UniProtKB/TrEMBL
  SOX_C UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016248 RatGTEx
SMART HMG UniProtKB/TrEMBL
Superfamily-SCOP HMG-box UniProtKB/TrEMBL
UniProt F7FNP9 ENTREZGENE, UniProtKB/TrEMBL
  Q4V7E4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-05 Sox18  SRY-box transcription factor 18  Sox18  SRY box 18  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-12 Sox18  SRY box 18  Sox18  SRY (sex determining region Y)-box 18  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Sox18  SRY (sex determining region Y)-box 18  Sox18  SRY-box containing gene 18  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Sox18  SRY-box containing gene 18  Sox18_predicted  SRY-box containing gene 18 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sox18_predicted  SRY-box containing gene 18 (predicted)      Symbol and Name status set to approved 70820 APPROVED