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Gene: Mrto4 (MRT4 homolog, ribosome maturation factor) Rattus norvegicus

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Symbol:

Mrto4

Name:

MRT4 homolog, ribosome maturation factor

RGD ID:

1311709

Description:

Predicted to be involved in nuclear-transcribed mRNA catabolic process; rRNA processing; and ribosomal large subunit biogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Orthologous to human MRTO4 (MRT4 homolog, ribosome maturation factor); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

60S acidic ribosomal protein PO; LOC298586; mRNA turnover 4 homolog; mRNA turnover 4 homolog (S. cerevisiae); mRNA turnover 4, ribosome maturation factor; mRNA turnover protein 4 homolog; MRT4, mRNA turnover 4, homolog; MRT4, mRNA turnover 4, homolog (S. cerevisiae); RGD1311709; ribosomal protein, large, P0-like; similar to ribosomal protein P0-like protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MRTO4 (MRT4 homolog, ribosome maturation factor)	HGNC	Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Mrto4 (mRNA turnover 4, ribosome maturation factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mrto4 (MRT4 homolog, ribosome maturation factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MRTO4 (MRT4 homolog, ribosome maturation factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MRTO4 (MRT4 homolog, ribosome maturation factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mrto4 (MRT4 homolog, ribosome maturation factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MRTO4 (MRT4 homolog, ribosome maturation factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MRTO4 (MRT4 homolog, ribosome maturation factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mrto4 (MRT4 homolog, ribosome maturation factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Mrto4 (MRT4 homolog, ribosome maturation factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MRTO4 (MRT4 homolog, ribosome maturation factor)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mrto4 (mRNA turnover 4, ribosome maturation factor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mrto4 (MRT4 homolog, ribosome maturation factor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F10E7.5	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MRT4	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	MRT4	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	RpLP0-like	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mrto4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mrto4	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	156,884,985 - 156,891,738 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	156,884,985 - 156,891,738 (-)	Ensembl				GRCr8
mRatBN7.2	5	151,601,780 - 151,608,533 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	151,601,780 - 151,608,287 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	154,300,433 - 154,307,186 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	156,074,793 - 156,081,547 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	156,055,735 - 156,062,489 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	157,814,142 - 157,820,889 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	157,815,361 - 157,820,889 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	161,553,854 - 161,560,601 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	158,149,143 - 158,154,671 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	149,982,626 - 149,988,154 (-)	NCBI		Celera
RGSC_v3.1	5	158,159,199 - 158,164,409 (-)	NCBI
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-alpha-phellandrene (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-palmitoylglycerol (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (EXP)

all-trans-retinoic acid (ISO)

alpha-phellandrene (ISO)

amitrole (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cobalt dichloride (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

DDE (ISO)

deoxynivalenol (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP,ISO)

dimethyl sulfoxide (ISO)

dioxygen (EXP,ISO)

endosulfan (EXP)

ethyl methanesulfonate (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

glafenine (EXP)

GSK-J4 (ISO)

inulin (ISO)

ivermectin (ISO)

ketoconazole (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

nefazodone (EXP)

nickel atom (ISO)

nimesulide (EXP)

okadaic acid (ISO)

ozone (ISO)

paraquat (EXP)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

pirinixic acid (EXP)

pregnenolone 16alpha-carbonitrile (ISO)

progesterone (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

Soman (EXP)

sulfadimethoxine (EXP)

sunitinib (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

thiram (ISO)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

nuclear-transcribed mRNA catabolic process (IBA)

ribosomal large subunit assembly (IEA)

ribosomal large subunit biogenesis (IBA)

ribosome biogenesis (IEA)

rRNA processing (IBA)

Cellular Component

cytoplasm (IEA)

nucleolus (IBA,IEA,ISO)

preribosome, large subunit precursor (IBA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:22658674	PMID:22681889

Genomics

Comparative Map Data

Mrto4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	156,884,985 - 156,891,738 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	156,884,985 - 156,891,738 (-)	Ensembl				GRCr8
mRatBN7.2	5	151,601,780 - 151,608,533 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	151,601,780 - 151,608,287 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	154,300,433 - 154,307,186 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	156,074,793 - 156,081,547 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	156,055,735 - 156,062,489 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	157,814,142 - 157,820,889 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	157,815,361 - 157,820,889 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	161,553,854 - 161,560,601 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	158,149,143 - 158,154,671 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	149,982,626 - 149,988,154 (-)	NCBI		Celera
RGSC_v3.1	5	158,159,199 - 158,164,409 (-)	NCBI
Cytogenetic Map	5	q36	NCBI

MRTO4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	19,251,805 - 19,260,128 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	19,251,796 - 19,260,128 (+)	Ensembl			hg38	GRCh38
GRCh37	1	19,578,299 - 19,586,622 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	19,450,662 - 19,459,209 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	19,323,604 - 19,331,064	NCBI
Celera	1	17,905,060 - 17,913,606 (+)	NCBI		Celera
Cytogenetic Map	1	p36.13	NCBI
HuRef	1	17,824,619 - 17,833,165 (+)	NCBI		HuRef
CHM1_1	1	19,687,405 - 19,695,952 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	19,075,329 - 19,083,650 (+)	NCBI		T2T-CHM13v2.0

Mrto4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	139,074,751 - 139,079,887 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	139,074,746 - 139,079,887 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	139,347,440 - 139,352,576 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	139,347,435 - 139,352,576 (-)	Ensembl			mm10	GRCm38
MGSCv37	4	138,903,360 - 138,908,213 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	138,619,521 - 138,624,374 (-)	NCBI		MGSCv36	mm8
Celera	4	141,134,667 - 141,139,519 (-)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	70.65	NCBI

Mrto4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955527	12,547 - 18,906 (-)	Ensembl
ChiLan1.0	NW_004955527	12,547 - 18,906 (-)	NCBI	ChiLan1.0	ChiLan1.0

MRTO4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	207,855,187 - 207,863,589 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	206,971,949 - 206,980,338 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	18,210,403 - 18,218,800 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	19,257,147 - 19,265,717 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	19,257,147 - 19,265,038 (+)	Ensembl			panPan2	panpan1.1

MRTO4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	79,360,897 - 79,367,038 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	79,360,970 - 79,366,935 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	75,875,788 - 75,881,913 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	79,983,604 - 79,989,727 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	79,983,677 - 79,989,638 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	76,744,427 - 76,750,539 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	77,754,345 - 77,760,465 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	78,825,044 - 78,831,167 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mrto4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	39,714,526 - 39,721,298 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	5,539,246 - 5,546,087 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	5,539,306 - 5,546,085 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MRTO4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	77,747,819 - 77,754,864 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	77,747,799 - 77,753,924 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	71,809,896 - 71,816,028 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MRTO4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	113,299,433 - 113,306,729 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	113,299,708 - 113,306,704 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666033	2,849,826 - 2,857,329 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mrto4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	4,400,731 - 4,407,180 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624764	4,401,005 - 4,406,157 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mrto4
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	18,833,889 - 18,839,447 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Mrto4
20 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	197
Count of miRNA genes:	146
Interacting mature miRNAs:	157
Transcripts:	ENSRNOT00000024326
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	130249266	172190305	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	116702075	161702075	Rat
1354583	Despr3	Despair related QTL3	4.98	0.0002	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	5	132930505	172190305	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	141212838	172190305	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	149642129	171146538	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	133789363	172190305	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	134369199	172190305	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136631198	172190305	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	156396728	172190305	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	112142946	157142946	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	112142946	157142946	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133081618	172190305	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	149805999	162987697	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138002522	170842766	Rat
1581505	Rf54	Renal function QTL 54			kidney physiology trait (VT:0002136)	kidney 20-HETE level (CMO:0001854)	5	133270647	172190305	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	112142946	157142946	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	141764300	172190305	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	148093485	172129029	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	133789363	172190305	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125969677	172190305	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	156396728	167181764	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	131708216	172190305	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	114131300	159131300	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	149661912	166600247	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	116702075	161702075	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	112142946	157142946	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	112142946	157142946	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	116702075	161702075	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	116702075	161702075	Rat
1298090	Bp155	Blood pressure QTL 155	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	156289283	171137955	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	114131300	159131300	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133081618	172190305	Rat

Markers in Region

BI275071

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	151,601,823 - 151,602,057 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	157,814,186 - 157,814,419	NCBI	Rnor6.0
Rnor_6.0	5	157,807,608 - 157,807,841	NCBI	Rnor6.0
Rnor_5.0	5	161,553,898 - 161,554,131	UniSTS	Rnor5.0
Rnor_5.0	5	161,547,422 - 161,547,655	UniSTS	Rnor5.0
RGSC_v3.4	5	158,147,946 - 158,148,179	UniSTS	RGSC3.4
Celera	5	149,981,429 - 149,981,662	UniSTS
RH 3.4 Map	5	1044.7	UniSTS
Cytogenetic Map	5	q36	UniSTS

MARC_6491-6492:996689696:1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	156,887,857 - 156,888,528 (+)	Marker Load Pipeline
mRatBN7.2	5	151,604,652 - 151,605,323 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	157,816,993 - 157,817,663	NCBI	Rnor6.0
Rnor_5.0	5	161,556,705 - 161,557,375	UniSTS	Rnor5.0
RGSC_v3.4	5	158,150,775 - 158,151,445	UniSTS	RGSC3.4
Celera	5	149,984,258 - 149,984,928	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106697	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168898	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234412	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000024326 ⟹ ENSRNOP00000024326

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,603,049 - 151,608,264 (-)	Ensembl
Rnor_6.0 Ensembl	5	157,815,361 - 157,820,889 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109067 ⟹ ENSRNOP00000084331

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	156,884,985 - 156,891,738 (-)	Ensembl
mRatBN7.2 Ensembl	5	151,601,780 - 151,608,287 (-)	Ensembl

RefSeq Acc Id:

NM_001106697 ⟹ NP_001100167

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,884,985 - 156,891,738 (-)	NCBI
mRatBN7.2	5	151,601,780 - 151,608,533 (-)	NCBI
Rnor_6.0	5	157,815,361 - 157,820,889 (-)	NCBI
Rnor_5.0	5	161,553,854 - 161,560,601 (-)	NCBI
RGSC_v3.4	5	158,149,143 - 158,154,671 (-)	RGD
Celera	5	149,982,626 - 149,988,154 (-)	RGD

Sequence:

show sequence

AGGCCTCAAGCCCCTCCCTCCGGAGAGCCATAGAGAGGAACCGGTTCGCGAGGGCCTTGGTGAA
GTGTTCCGGATTCGGAAGCCGCGGCGATCAGGGGGGCCGAAGGGACTGGAAGGCTCTGGAACCT
GGGCAGAGAAGTGGCCTTCCAGGCCCTAGGCAGAACGCAGGCAGGGAAGAGAGGGCCCACCACA
CTTCGGGTCAGGCACACGAGAGAGGCAGCCCCGAGCGCCGCCCCACAAGCCTCTGCGGCACCCG
GGTCCTGACGGGCCGCCGGGTCTTCCGCCGCACGTGCCTTTAGCGCGATGCCCAAATCCAAGCG
AGACAAGAAAGTTTCCTTAACAAAAACTGCCAAGAAAGGCTTGGAACTGAAGCAGAACCTGATA
GAAGAGTAAGTAACACTGGTGTCAGTCACGCCAGTGGAAGCTTAAAGGCCTATGACCGCTTCTC
TTGTGTGAGGCCAGAGTTGCCCAGCCCGTGCTGCGCCTCAGCTCCAGAGCCTCATGAATTGTCC
CACAGCTTCGGAAATGCGTGGACACCTACAAGTACCTCTTCATCTTCTCTGTGGCCAACATGAG
GAACAGCAAGCTGAAGGACATCCGGAATGCCTGGAAGCACAGCCGGATGTTCTTTGGCAAAAAC
AAGGTGATGATGGTGGCCTTGGGTCGAAGCCCGTCTGATGAATACAAAGACAACCTACATCAGG
TCAGCAAGAAGTTGAGAGGTGAAGTTGGGCTCCTTTTTACCAACCGCACGAAGGAGGAGGTGAA
TGAGTGGTTCACAAAGTATACAGAAATGGATTTTGCTCGAGCGGGGAACAAAGCAACTTTAACT
GTGAGCCTGGATCCAGGGCCGCTGAAACAGTTCCCTCATTCCATGGAGCCACAGCTGAGGCAGC
TGGGTCTGCCCACTGCCCTCAAGAAAGGTGTGGTGACCTTGCTGTCTGACTATGAAGTGTGCAA
GGAGGGTGACGTGCTGACCCCAGAGCAGGCCCGTGTCCTGAAGCTGTTTGGGTATGAGATGGCC
GAATTCAAAGTGACCATCAAATACATGTGGGATGCCCAGTCAGGGAGATTCCAGCAGATGGACG
ATGACCTTCCCGAGAGCGCGCCTGAGTCTGAGGGGGAGTCTGAGGAGGAGGAGGACGACAGCTG
ACTCTGGGAACCAGAACCAAGGCCTTCCAGCAAGTACTTCATCTCCACTGGACGCCCCCAGGAC
TGCTGTCGCCCCCTAGAGGGAGCGGCTGGTTTTTTTGCTATGGATAAAGACAAGGGAGGTGCTG
GGCAGTGACTTTGTTTCTATAGAGAATAAAATTTTGTCTGCAGGGTGCTCCCTGTAGACAGCAG
AGACTCTTTAT

hide sequence

RefSeq Acc Id:

NM_001399076 ⟹ NP_001386005

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,884,985 - 156,891,738 (-)	NCBI
mRatBN7.2	5	151,601,780 - 151,608,533 (-)	NCBI

RefSeq Acc Id:

XM_008764230 ⟹ XP_008762452

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,886,223 - 156,891,478 (-)	NCBI
mRatBN7.2	5	151,603,024 - 151,608,281 (-)	NCBI
Rnor_6.0	5	157,814,142 - 157,818,449 (-)	NCBI

Sequence:

show sequence

TTTCCTTAACAAAAACTGCCAAGAAAGGCTTGGAACTGAAGCAGAACCTGATAGAAGAGGCCAG
AGTTGCCCAGCCCGTGCTGCGCCTCAGCTCCAGAGCCTCATGAATTGTCCCACAGCTTCGGAAA
TGCGTGGACACCTACAAGTACCTCTTCATCTTCTCTGTGGCCAACATGAGGAACAGCAAGCTGA
AGGACATCCGGAATGCCTGGAAGCACAGCCGGATGTTCTTTGGCAAAAACAAGGTGATGATGGT
GGCCTTGGGTCGAAGCCCGTCTGATGAATACAAAGACAACCTACATCAGGTCAGCAAGAAGTTG
AGAGGTGAAGTTGGGCTCCTTTTTACCAACCGCACGAAGGAGGAGGTGAATGAGTGGTTCACAA
AGTATACAGAAATGGATTTTGCTCGAGCGGGGAACAAAGCAACTTTAACTGTGAGCCTGGATCC
AGGGCCGCTGAAACAGTTCCCTCATTCCATGGAGCCACAGCTGAGGCAGCTGGGTCTGCCCACT
GCCCTCAAGAAAGGTGTGGTGACCTTGCTGTCTGACTATGAAGTGTGCAAGGAGGGTGACGTGC
TGACCCCAGAGCAGGCCCGTGTCCTGAAGCTGTTTGGGTATGAGATGGCCGAATTCAAAGTGAC
CATCAAATACATGTGGGATGCCCAGTCAGGGAGATTCCAGCAGATGGACGATGACCTTCCCGAG
AGCGCGCCTGAGTCTGAGGGGGAGTCTGAGGAGGAGGAGGACGACAGCTGACTCTGGGAACCAG
AACCAAGGCCTTCCAGCAAGTACTTCATCTCCACTGGACGCCCCCAGGACTGCTGTCGCCCCCT
AGAGGGAGCGGCTGGTTTTTTTGCTATGGATAAAGACAAGGGAGGTGCTGGGCAGTGACTTTGT
TTCTATAGAGAATAAAATTTTGTCTGCAGGGTGCTCCCTGTAGACAGCAGAGACTCTTTATAAA
GGCCTTCGGCTGTGCTCCAGCCTAGTCGGGCTAGGGCTGGGTGGGCCAGCACTGCAGATGGCTG
AGAGCACGCCTGGATTTGGGTGTCTTTGTCCGTTTGCTTGCAGTGGGTTTGCTGAGGAAAGTTA
ATTCTCTGGAAGCTTGATCACTTAAAACATAAATAAGCACACAGATACGTGCAAGCCGGGGGTA
AAATATGAGGAACACAGGCTTGCCACAGGGCGGTGGAGGGGATTGGGAGCAAGTGGAGTTTGAG
TCAGGTTCTCACTGAAGCACAGACTGGTCTTGATCTTACAGTAGTTTCTGGCCTCTGCCCCTCA
AGTGCTACCACACTTGGCTGACTAGTAGTGATTAGTAGCTGTGTGCTGTGCGAGTCAGTGGTAA
GGCATCATAAACCATGCTTAAGGCCAGCAGGTCCCTCCCTGGCAGCACACAGAAACTGAGGAAA
GTTGTTGGACCTGTGGGTCAGAAAATCCTCAGAGTTCCTGACCTCTACCCTAGAGGAGGGATGT
GGGGGTTAAACAGCAACACTGAATAAGATGGGCCTTGGGTCTTCATAATCATGCCCAAAAAACC
CAGGGCAAGCCAATATGATAATGCTTGGAATGCCAGCACCTCAGGAGGCTGAGGTAGGATTGAA
AGTTTGAGGCCAAGCCAGGCAGAGGGAGGCCAATCTCTGAATTGGAGGCCACTCATGGCTAAAT
AAAGCCTATCTCAAAAAAAGTTTGATACCAATCAACTATAAGGCTGAAAAAAGGCAGGCTTGGG
GAAGAGCACCGACTGCTCTTCCAGAGGTCCTGAGTTCAATTCCCAGCAACCACATGGTGGCTCA
CAACCATCTGTAATGGGATCTGATGCCCTTTTCTGGTGTGTCTGAAGACAGCTGTAGTGTTCTT
ATATATAATAAATAAATCATTATAGGAAAAAAAAAAGGGCAGGCTTGGTTGTATGCACCAGAAA
TTGAAAGCTAGAGACAAGAGACCTGATAGGAGTTCAAGGCCAGCCTAGAGTATATGGCATTTTG
TCTTAAAAAGAAAAGGCCAGGGTGGTGGTGGCTCACACCTTTAATACCAGCACTTGGGAGGCAG
AATTCAGGACAGCCAGGGCTACACACAGATACATTGTCTCAAAGGGGAAAGTAAGAAAGACAAG
TGACATGTTTCAGCAGACCGAAGCACTTGCTGCCAAATCAATTAAAATGTTGCTTAGTACTCAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100167	(Get FASTA)	NCBI Sequence Viewer
	NP_001386005	(Get FASTA)	NCBI Sequence Viewer
	XP_008762452	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68898	(Get FASTA)	NCBI Sequence Viewer
	EDL80918	(Get FASTA)	NCBI Sequence Viewer
	EDL80919	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000084331
	ENSRNOP00000084331.2

RefSeq Acc Id:	NP_001100167 ⟸ NM_001106697
- Peptide Label:	isoform 2
- UniProtKB:	F1LTU4 (UniProtKB/TrEMBL), A6ITL8 (UniProtKB/TrEMBL), B5DF25 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRNSKLKDIRNAWKHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKKLRGEVGLLFTNRTKEE VNEWFTKYTEMDFARAGNKATLTVSLDPGPLKQFPHSMEPQLRQLGLPTALKKGVVTLLSDYEV CKEGDVLTPEQARVLKLFGYEMAEFKVTIKYMWDAQSGRFQQMDDDLPESAPESEGESEEEEDD S hide sequence

RefSeq Acc Id:	XP_008762452 ⟸ XM_008764230
- Peptide Label:	isoform X1
- UniProtKB:	F1LTU4 (UniProtKB/TrEMBL), A6ITL8 (UniProtKB/TrEMBL), B5DF25 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRNSKLKDIRNAWKHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKKLRGEVGLLFTNRTKEE VNEWFTKYTEMDFARAGNKATLTVSLDPGPLKQFPHSMEPQLRQLGLPTALKKGVVTLLSDYEV CKEGDVLTPEQARVLKLFGYEMAEFKVTIKYMWDAQSGRFQQMDDDLPESAPESEGESEEEEDD S hide sequence

Ensembl Acc Id:

ENSRNOP00000024326 ⟸ ENSRNOT00000024326

Ensembl Acc Id:

ENSRNOP00000084331 ⟸ ENSRNOT00000109067

RefSeq Acc Id:	NP_001386005 ⟸ NM_001399076
- Peptide Label:	isoform 1
- UniProtKB:	A0A8I5ZWZ6 (UniProtKB/TrEMBL), A6ITL7 (UniProtKB/TrEMBL), B5DF25 (UniProtKB/TrEMBL)

Protein Domains

Large ribosomal subunit protein uL10-like insertion

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LTU4-F1-model_v2	AlphaFold	F1LTU4	1-193	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694206

Promoter ID:

EPDNEW_R4730

Type:

initiation region

Name:

Mrto4_1

Description:

MRT4 homolog, ribosome maturation factor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R4731

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	157,820,629 - 157,820,689	EPDNEW

RGD ID:

13694207

Promoter ID:

EPDNEW_R4731

Type:

initiation region

Name:

Mrto4_2

Description:

MRT4 homolog, ribosome maturation factor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R4730

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	157,820,874 - 157,820,934	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311709	AgrOrtholog
BioCyc Gene	G2FUF-39415	BioCyc
Ensembl Genes	ENSRNOG00000017979	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000109067	ENTREZGENE
	ENSRNOT00000109067.2	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.1730	UniProtKB/TrEMBL
	3.90.105.20	UniProtKB/TrEMBL
InterPro	Mrt4	UniProtKB/TrEMBL
	Ribosomal_L10-like_sf	UniProtKB/TrEMBL
	Ribosomal_L10/acidic_P0	UniProtKB/TrEMBL
	Ribosome_Assembly_uL10	UniProtKB/TrEMBL
	RL10_insert_sf	UniProtKB/TrEMBL
	RL10P_insert	UniProtKB/TrEMBL
KEGG Report	rno:298586	UniProtKB/TrEMBL
NCBI Gene	298586	ENTREZGENE
PANTHER	MRNA TURNOVER PROTEIN 4 HOMOLOG	UniProtKB/TrEMBL
	MRNA TURNOVER PROTEIN 4 MRTO4	UniProtKB/TrEMBL
Pfam	Ribosomal_L10	UniProtKB/TrEMBL
	RL10P_insert	UniProtKB/TrEMBL
PhenoGen	Mrto4	PhenoGen
RatGTEx	ENSRNOG00000017979	RatGTEx
Superfamily-SCOP	SSF160369	UniProtKB/TrEMBL
UniProt	A0A8I5ZWZ6	ENTREZGENE, UniProtKB/TrEMBL
	A6ITL7	ENTREZGENE, UniProtKB/TrEMBL
	A6ITL8	ENTREZGENE, UniProtKB/TrEMBL
	B5DF25	ENTREZGENE, UniProtKB/TrEMBL
	F1LTU4	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-17	Mrto4	MRT4 homolog, ribosome maturation factor	Mrto4	mRNA turnover 4, ribosome maturation factor	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2022-04-25	Mrto4	mRNA turnover 4, ribosome maturation factor	Mrto4	MRT4 homolog, ribosome maturation factor	Name changed	629549	APPROVED
2015-07-09	Mrto4	MRT4 homolog, ribosome maturation factor	Mrto4	mRNA turnover 4 homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-25	Mrto4	mRNA turnover 4 homolog (S. cerevisiae)	Mrto4	MRT4, mRNA turnover 4, homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-27	Mrto4	MRT4, mRNA turnover 4, homolog (S. cerevisiae)	RGD1311709_predicted	similar to ribosomal protein P0-like protein; 60S acidic ribosomal protein PO; ribosomal protein, large, P0-like (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1311709_predicted	similar to ribosomal protein P0-like protein; 60S acidic ribosomal protein PO; ribosomal protein, large, P0-like (predicted)	LOC298586_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC298586_predicted	similar to ribosomal protein P0-like protein; 60S acidic ribosomal protein PO; ribosomal protein, large, P0-like (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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