Krtap14l (keratin associated protein 14 like) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Krtap14l (keratin associated protein 14 like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Krtap14l
Name: keratin associated protein 14 like
RGD ID: 1311682
Description: Predicted to be located in cytosol and keratin filament. Orthologous to several human genes including KRTAP13-1 (keratin associated protein 13-1); KRTAP13-2 (keratin associated protein 13-2); and KRTAP13-3 (keratin associated protein 13-3); INTERACTS WITH copper atom; copper(0); phenethyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: keratin associated protein 14; keratin-associated protein 13-1; Krtap14; LOC363739
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81141,571,945 - 41,572,732 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1141,571,945 - 41,572,732 (-)EnsemblGRCr8
mRatBN7.21128,085,729 - 28,086,516 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,086,010 - 28,086,516 (-)EnsemblmRatBN7.2
Rnor_6.01128,735,488 - 28,736,000 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1128,735,494 - 28,736,000 (-)Ensemblrn6Rnor6.0
Rnor_5.01132,355,569 - 32,356,109 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41128,608,680 - 28,609,417 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1127,801,551 - 27,802,093 (-)NCBICelera
RGSC_v3.11128,608,904 - 28,609,417 (-)NCBI
Cytogenetic Map11q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Comprehensive gene review and curation RGD comprehensive gene curation

Genomics

Variants

.
Variants in Krtap14l
3 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:12
Count of miRNA genes:10
Interacting mature miRNAs:12
Transcripts:ENSRNOT00000064058
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11381815448818154Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
integumental system
mesenchyme
renal system
reproductive system
8 1 1 9 1 3

Sequence


Ensembl Acc Id: ENSRNOT00000064058   ⟹   ENSRNOP00000060047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1141,571,945 - 41,572,732 (-)Ensembl
mRatBN7.2 Ensembl1128,086,010 - 28,086,516 (-)Ensembl
Rnor_6.0 Ensembl1128,735,494 - 28,736,000 (-)Ensembl
RefSeq Acc Id: NM_001408809   ⟹   NP_001395738
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81141,571,945 - 41,572,732 (-)NCBI
mRatBN7.21128,085,729 - 28,086,516 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001395738 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM10662 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000060047
  ENSRNOP00000060047.2
Ensembl Acc Id: ENSRNOP00000060047   ⟸   ENSRNOT00000064058
RefSeq Acc Id: NP_001395738   ⟸   NM_001408809
- UniProtKB: D3ZJ37 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZJ37-F1-model_v2 AlphaFold D3ZJ37 1-169 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698036
Promoter ID:EPDNEW_R8555
Type:single initiation site
Name:Krtap14l_1
Description:keratin associated protein 14 like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01128,736,055 - 28,736,115EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311682 AgrOrtholog
BioCyc Gene G2FUF-22015 BioCyc
Ensembl Genes ENSRNOG00000042680 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064058 ENTREZGENE
  ENSRNOT00000064058.3 UniProtKB/TrEMBL
InterPro PMG UniProtKB/TrEMBL
NCBI Gene 363739 ENTREZGENE
Pfam PMG UniProtKB/TrEMBL
PhenoGen Krtap14l PhenoGen
RatGTEx ENSRNOG00000042680 RatGTEx
UniProt D3ZJ37 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Krtap14l  keratin associated protein 14 like  LOC684640  similar to keratin associated protein 13-1  Data merged from RGD:1587932 1643240 APPROVED
2008-05-02 Krtap14l  keratin associated protein 14 like  Krtap14_predicted  keratin associated protein 14 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC684640  similar to keratin associated protein 13-1      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Krtap14_predicted  keratin associated protein 14 (predicted)      Symbol and Name status set to approved 70820 APPROVED