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Gene: Tifab (TIFA inhibitor) Rattus norvegicus

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Symbol:

Tifab

Name:

TIFA inhibitor

RGD ID:

1311681

Description:

Predicted to enable deubiquitinase activator activity. Predicted to be involved in several processes, including cochlea morphogenesis; cranial nerve development; and hard palate morphogenesis. Predicted to act upstream of with a negative effect on toll-like receptor signaling pathway. Predicted to act upstream of or within several processes, including hemopoiesis; lipopolysaccharide-mediated signaling pathway; and regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator. Orthologous to human TIFAB (TIFA inhibitor); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC364674; MGC108845; RGD1311681; similar to MGC37193 protein; TIFA inhibitor B; TIFA-like protein; TRAF-interacting protein with FHA domain-containing protein B; TRAF-interacting protein with forkhead-associated domain, family member B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TIFAB (TIFA inhibitor)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tifab (TRAF-interacting protein with forkhead-associated domain, family member B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TIFAB (TIFA inhibitor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TIFAB (TIFA inhibitor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tifab (TIFA inhibitor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TIFAB (TIFA inhibitor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TIFAB (TIFA inhibitor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tifab (TIFA inhibitor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tifab (TIFA inhibitor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Tifab (TRAF-interacting protein with forkhead-associated domain, family member B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TIFAB (TIFA inhibitor)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	8,438,622 - 8,441,750 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	8,433,862 - 8,444,360 (+)	Ensembl				GRCr8
mRatBN7.2	17	8,433,406 - 8,436,541 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	8,431,635 - 8,436,592 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	8,449,150 - 8,452,171 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	9,982,163 - 9,985,180 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	8,445,541 - 8,448,562 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	9,234,948 - 9,239,266 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	9,236,249 - 9,239,265 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	11,393,749 - 11,400,318 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	14,409,442 - 14,412,459 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	8,517,840 - 8,520,857 (+)	NCBI		Celera
RGSC_v3.1	17	14,409,441 - 14,412,458 (+)	NCBI
Cytogenetic Map	17	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

buta-1,3-diene (ISO)

cadmium dichloride (EXP)

CGP 52608 (ISO)

chloroprene (EXP,ISO)

Cuprizon (EXP)

diquat (ISO)

gardiquimod (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

malathion (ISO)

nickel atom (ISO)

oxaliplatin (EXP)

ozone (ISO)

protein kinase inhibitor (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

succimer (ISO)

testosterone (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

topotecan (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

auditory behavior (ISO)

cochlea development (ISO)

cochlea morphogenesis (ISO)

craniofacial suture morphogenesis (ISO)

genitalia development (ISO)

genitalia morphogenesis (ISO)

hard palate morphogenesis (ISO)

hematopoietic progenitor cell differentiation (ISO)

inner ear development (ISO)

inner ear morphogenesis (ISO)

learned vocalization behavior (ISO)

lipopolysaccharide-mediated signaling pathway (ISO)

mastication (ISO)

myeloid cell differentiation (ISO)

negative regulation of canonical NF-kappaB signal transduction (ISO)

negative regulation of relaxation of muscle (ISO)

negative regulation of saliva secretion (ISO)

neuromuscular process controlling balance (ISO)

peristalsis (ISO)

positive regulation of canonical NF-kappaB signal transduction (IEA)

regulation of canonical NF-kappaB signal transduction (ISO)

regulation of gene expression (ISO)

regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator (ISO)

regulation of muscle organ development (ISO)

thorax and anterior abdomen determination (ISO)

toll-like receptor signaling pathway (IBA,ISO)

trigeminal nerve development (ISO)

vestibulocochlear nerve formation (ISO)

Cellular Component

cytoplasm (ISO)

Molecular Function

deubiquitinase activator activity (IBA,ISO)

protein binding (ISO)

ubiquitin-specific protease binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:23419067

Genomics

Comparative Map Data

Tifab
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	8,438,622 - 8,441,750 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	8,433,862 - 8,444,360 (+)	Ensembl				GRCr8
mRatBN7.2	17	8,433,406 - 8,436,541 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	8,431,635 - 8,436,592 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	8,449,150 - 8,452,171 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	9,982,163 - 9,985,180 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	8,445,541 - 8,448,562 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	9,234,948 - 9,239,266 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	9,236,249 - 9,239,265 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	11,393,749 - 11,400,318 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	14,409,442 - 14,412,459 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	8,517,840 - 8,520,857 (+)	NCBI		Celera
RGSC_v3.1	17	14,409,441 - 14,412,458 (+)	NCBI
Cytogenetic Map	17	p14	NCBI

TIFAB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	135,444,226 - 135,452,351 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	135,444,226 - 135,452,351 (-)	Ensembl			hg38	GRCh38
GRCh37	5	134,779,916 - 134,788,041 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	134,812,457 - 134,815,988 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	5	130,908,347 - 130,911,878 (-)	NCBI		Celera
Cytogenetic Map	5	q31.1	NCBI
HuRef	5	129,972,262 - 129,975,793 (-)	NCBI		HuRef
CHM1_1	5	134,217,201 - 134,220,732 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	135,971,397 - 135,979,522 (-)	NCBI		T2T-CHM13v2.0

Tifab
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	56,318,917 - 56,326,816 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	56,321,517 - 56,326,698 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	56,173,703 - 56,179,002 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	56,173,704 - 56,178,885 (-)	Ensembl			mm10	GRCm38
MGSCv37	13	56,275,064 - 56,280,246 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	56,183,333 - 56,188,423 (-)	NCBI		MGSCv36	mm8
Celera	13	57,228,509 - 57,233,670 (-)	NCBI		Celera
Cytogenetic Map	13	B1	NCBI
cM Map	13	30.06	NCBI

TIFAB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	130,732,121 - 130,741,427 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	128,871,681 - 128,880,987 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	130,836,697 - 130,846,050 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	136,982,454 - 136,985,986 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	136,983,040 - 136,983,525 (-)	Ensembl			panPan2	panpan1.1

TIFAB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	23,492,317 - 23,495,825 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	23,492,867 - 23,493,352 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	22,241,429 - 22,244,942 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	24,309,269 - 24,312,784 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	24,309,819 - 24,310,304 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	22,997,445 - 23,000,957 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	22,863,108 - 22,866,620 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	23,513,134 - 23,516,647 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tifab
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	123,595,278 - 123,596,398 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936597	2,620,661 - 2,621,302 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TIFAB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	137,672,407 - 137,678,612 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	137,675,245 - 137,678,880 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TIFAB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	38,228,904 - 38,232,892 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666034	39,683,902 - 39,686,777 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tifab
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624733	11,578,934 - 11,587,250 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tifab
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	14	81,898,205 - 81,899,672 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tifab
26 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	317
Count of miRNA genes:	182
Interacting mature miRNAs:	215
Transcripts:	ENSRNOT00000015878
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354613	Kidm14	Kidney mass QTL 14	6.2		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	17	1	36045694	Rat
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	43999106	Rat
2293664	Bmd28	Bone mineral density QTL 28	5.1	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	17	4360057	27233623	Rat
2324619	Coatc4	Coat color QTL 4		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)	17	1	21499218	Rat
1300123	Bp194	Blood pressure QTL 194	2.82		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	2120843	42054133	Rat
2303627	Vencon8	Ventilatory control QTL 8		0.001	respiration trait (VT:0001943)	tidal volume (CMO:0000222)	17	4733534	49733534	Rat
1581553	Pur14	Proteinuria QTL 14	5.3	0.0001	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	17	7985243	16523460	Rat
2302377	Scl61	Serum cholesterol level QTL 61	4.36		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	17	6221998	58177198	Rat
631207	Niddm41	Non-insulin dependent diabetes mellitus QTL 41			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	1	38037084	Rat
10401807	Kidm52	Kidney mass QTL 52			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	1	31706603	Rat
10054088	Scort28	Serum corticosterone level QTL 28	2.04	0.0102	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	4733534	49733534	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	43999106	Rat
2293648	Bmd31	Bone mineral density QTL 31	4.5	0.0001	femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	17	4360057	27233623	Rat
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	43999106	Rat
1641902	Colcr7	Colorectal carcinoma resistance QTL 7	3.35	0.0044	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	17	2120843	22087569	Rat
1549900	Iddm20	Insulin dependent diabetes mellitus QTL 20	3.7		pancreas integrity trait (VT:0010560)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	17	1	22181410	Rat
9590316	Scort21	Serum corticosterone level QTL 21	4.75	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	1	22877318	Rat

Markers in Region

RPLP1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	8,431,994 - 8,432,082 (+)	MAPPER	mRatBN7.2
mRatBN7.2	8	62,395,183 - 62,395,271 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	66,863,319 - 66,863,406	NCBI	Rnor6.0
Rnor_6.0	17	9,234,720 - 9,234,807	NCBI	Rnor6.0
Rnor_5.0	17	11,393,529 - 11,393,616	UniSTS	Rnor5.0
Rnor_5.0	8	66,595,700 - 66,595,787	UniSTS	Rnor5.0
RGSC_v3.4	8	66,047,396 - 66,047,483	UniSTS	RGSC3.4
RGSC_v3.4	17	14,407,913 - 14,408,000	UniSTS	RGSC3.4
Celera	17	8,516,311 - 8,516,398	UniSTS
Celera	8	61,814,968 - 61,815,055	UniSTS
Cytogenetic Map	17	p14	UniSTS
Cytogenetic Map	8	q24	UniSTS

RH131325

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	8,436,193 - 8,436,380 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	9,238,919 - 9,239,105	NCBI	Rnor6.0
Rnor_5.0	17	11,397,728 - 11,397,914	UniSTS	Rnor5.0
RGSC_v3.4	17	14,412,112 - 14,412,298	UniSTS	RGSC3.4
Celera	17	8,520,510 - 8,520,696	UniSTS
RH 3.4 Map	17	74.4	UniSTS
Cytogenetic Map	17	p14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	64	155	91	90	59	92	59	6	350	189	11	129	78	92	31	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001025029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008771443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC091188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474032	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000015878 ⟹ ENSRNOP00000015878

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	8,433,896 - 8,441,805 (+)	Ensembl
mRatBN7.2 Ensembl	17	8,431,635 - 8,436,592 (+)	Ensembl
Rnor_6.0 Ensembl	17	9,236,249 - 9,239,265 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107660 ⟹ ENSRNOP00000087435

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	8,437,420 - 8,444,360 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116729 ⟹ ENSRNOP00000083675

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	8,438,663 - 8,442,191 (+)	Ensembl
mRatBN7.2 Ensembl	17	8,433,406 - 8,436,544 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000128696 ⟹ ENSRNOP00000103745

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	8,437,590 - 8,442,191 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000141048 ⟹ ENSRNOP00000111504

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	8,433,862 - 8,441,884 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000145069 ⟹ ENSRNOP00000103985

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	8,433,879 - 8,441,805 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000167627 ⟹ ENSRNOP00000108983

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	8,434,112 - 8,441,805 (+)	Ensembl

RefSeq Acc Id:

NM_001025029 ⟹ NP_001020200

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	8,438,733 - 8,441,750 (+)	NCBI
mRatBN7.2	17	8,433,524 - 8,436,541 (+)	NCBI
Rnor_6.0	17	9,236,249 - 9,239,266 (+)	NCBI
Rnor_5.0	17	11,393,749 - 11,400,318 (+)	NCBI
RGSC_v3.4	17	14,409,442 - 14,412,459 (+)	RGD
Celera	17	8,517,840 - 8,520,857 (+)	RGD

Sequence:

show sequence

CCAGGCCCTGCCTGAGCCCATGGCTGCAGAGTTAGTGCCAGGCATACCCTGGCAGTAAGCTGGA
AGCACCATATCTTCTCCTTCAAGAGGGGTGCTCCCAAGGGCACCCTGTCTCCACAGCACCTGGA
CTGACACCCGGCGCAAAGAAGAGACTCTGCAAGAGTTTGTTCATTGCGTGCTTACCAGATACAA
GAAAGCCTGTCGTGTCTGTTCCTCTGTTCCTGTAAAGCAGGGGCAAACTGTCTCCAAATGGCCT
GAGGGCTATCAGGCCCCACCCTATAAGCTGGATCTATGGAGAGGCCCCTCACAGTCCTGCAGGT
GAGCCTGTACCACCCGACACAGGGCCCGGTCGCCTTTGCCAAAGTTCCGCTGCAGCTGCAACAC
GACGCCAGCCGGTTGCTGGTTGGGCGAGGGCAGGACACCCACCTCCAGCTGCAGCTGCCACAGT
TGTCCCGCCACCATTTGTGCCTGGAGCCCTACCTGGAGAAAGGCAGCAACCTGCTGGCCTTCTG
CCTCAAGGTGCTGACCCGCCAGAGCTGTGTGTGGGTCAACGGGTTGCCGCTGAGGTACCTGGAG
CAGGTTCCCCTGCACTCCGTCAACAGAATCTCCTTCTCTGGCATCCAGATGCTCATCCGCAAAG
AGGGGGGCGCCTCCCTTGAGGCCTTTGTCTGCTATTTCCATCTCAGCCCCTCGCCCCTGATTTA
CAGACCCAAGGCTCAGGAGACAGACGAATGAATGGGAAAACACTGTCAAGAAAGAGACTCCCCC
TGTTTTGGGGGGAGGCAACTCGTGATCTCCTGGGGTCTCTCCACGGCCCCTCCCCGTCTCTGTT
TCCCTGCCAAGCCCTGGAGAAGCAACAGAAGCAAAGCACCAGAGGAAGCCTCGAGACCCGGCAC
CCCACCAGCCCCGCTGCGGAGAGCAAGCCTTACAAAAGCGGGGTTTGAGATGGTTGAGTTACGT
CAGAGTTCACATGTAAAGCCTGCTGGCCGCCATGTTCACAGGGCACGGATTCGGTAAACTTGGA
GCGGCCCAGGGACGGAGAAGGGCCCTTCATGGCTCCAGGGAATGGGAACTTCATATACTTTTAG
AGGCCCTGAGGGGTTCTGGGAGCCCCTCCCAGCATTCTGCCCGCCCCCTCCCCATTTCCTCCCT
TGTCTGGCTAGGAGTTACTTTATGTCCCTCGTCTCCCATGCTGCCTAAGGGCAGGAGCATGGGG
TTGCGGCAGGAATGCAAGGACACGCAAGGAGGAATTACGTTTGTGGTAGCTCGGGGTTACCTTC
AGCTTTCAAATACCCACAGGCGCTCAGGGCTTAGGAGAGCCTGTGTTTAATAAACTAAAAGTAT
TTCATTAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006253578 ⟹ XP_006253640

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	8,438,622 - 8,441,750 (+)	NCBI
mRatBN7.2	17	8,433,406 - 8,436,541 (+)	NCBI
Rnor_6.0	17	9,234,948 - 9,239,266 (+)	NCBI
Rnor_5.0	17	11,393,749 - 11,400,318 (+)	NCBI

Sequence:

show sequence

TAAAAACCGCATCCATCCACGGAGGTAGTCAGGATTTCAGTACTGACTCTAGGGTACACAGGAA
AGACCCAGGAATAGCTGAGTCCAAGTTCCCCAATGCTCTCCAGAGCTCCCCTGAGCAAGAGCAG
CCTCTGAGGCAATTTGCTGGAGGACATCTTCCTGAAAGCAGGCAGCAGGAGAGCCTCTGGAATG
AGTGAGTCTCGCTTGGGGGGTTAGGGTTGGGAGCAATGTGTGATGGTCCCCTCTCTCATTCCAC
CCAACCAACTGCAGGCCAGGATTGGGCTATCCTCGTCTTACCTGCTTATATGTCCTCCTTATTC
TGCTGGTCTTTCTAAGCACATGCAAGCCTTCCTTGAAATTACTTTTCATTCCATTCTCTACGTA
TTAGCCTGATACCGAGGAGACAGTTTTATTCTCTTACCGATTCTGTGTGAAATCGGAGCGTGCA
TCCTTACCTCACTGTGTCTACCCTCAGTTTGTGTCTCTGCATCCTGGACAACAGGGAGGAATTT
GAAACTCTGTAACTATATGTAACCCTCCCACCTAGGCTGACTTTAATAATACGTGCATATGTGT
TTATATATTTTAAATATATAGAGAGGACACATATAATGAAGCCCATTTTAGAACGCCATCATTG
TCTCGTTGAGCTGGACGGGCAGGTCATTCTTCAGTGACAGGATCCTGAGGAACAAAAGGGCAGT
GGGGTCAGAAAATAAAGAAGGTAGGGAAGTTTGTGCTCTGGAGATCTTGTACAAGCTATGTCTT
GTTCCAAACAGGTTCATCCGGAAGTAGGGTATCTGATATGTCACTTTAAGGAGAGAAATGGGAC
AAAGTCAGCAGGTGGCCTTCTGCGTGCGCTGAATGAGGCCTATTCTCATGAGTGGCCACATCCT
CCTGTCCCTTCCCATGAGTGGCCATGCTCTCCCGTCCCCGTGTCTCATTCTCTTCTGTGATACC
CTAGATATTCTCTATTAGTATGGCTTCCTTGGCCAACCCCAGACCATTGGAAGGAACACCTCAT
AATCCAGGAGCTCTCTGGCCTCACAGGGGAAAAGAAGACCATCAATACTCTGTGGTCTCTGGGG
CTGAAATAGTAGAGGCTGGGAGTACCAAGACCCAGGAAGTCCTACCATCAAGAGGCCCCTCCTA
CAAGGACACCAGTTTCACAACTCAGGCAGTAGGTTCCACTTCTGCAAGAGAAAACGACACTTTG
ATTTCTCTCCTAGAGGAAAAAGGAGGAACGGCAGAGTTGACGCCTTCTCTGACACAGTCCATTC
TTGAAAAGCGGAAGAGCCCACCCAGGCCCTGCCTGAGCCCATGGCTGCAGAGTTAGTGCCAGGC
ATACCCTGGCAGTAAGACACTGAAGGACAAGTTCCTGGAGGAGCTGTGGGACCTCGTGTGCATT
TCCCGGAGCTCCTGAGGGTCTTCAGTGAGCCAGATTTTCCCTTCTGCCCACTGTCTCCACCAGC
ATTCACCTCTGCCCAGATGTTTAAGAAAGGCGAGCCCTCAACCCGGTGCTGAGCCCCTGAACCC
AGTGCCGGGCCCTCTGGAAACACCACCGATAAGACGCTGGCTGTTGTTACCTTCTGTGTCGCGC
TCAGGGACCTTTTATGTTGCTCTGTACCCCCATAGCTGGAAGCACCATATCTTCTCCTTCAAGA
GGGGTGCTCCCAAGGGCACCCTGTCTCCACAGCACCTGGACTGACACCCGGCGCAAAGAAGAGA
CTCTGCAAGAGTTTGTTCATTGCGTGCTTACCAGATACAAGAAAGCCTGTCGTGTCTGTTCCTC
TGTTCCTGTAAAGCAGGGGCAAACTGTCTCCAAATGGCCTGAGGGCTATCAGGCCCCACCCTAT
AAGCTGGATCTATGGAGAGGCCCCTCACAGTCCTGCAGGTGAGCCTGTACCACCCGACACAGGG
CCCGGTCGCCTTTGCCAAAGTTCCGCTGCAGCTGCAACACGACGCCAGCCGGTTGCTGGTTGGG
CGAGGGCAGGACACCCACCTCCAGCTGCAGCTGCCACAGTTGTCCCGCCACCATTTGTGCCTGG
AGCCCTACCTGGAGAAAGGCAGCAACCTGCTGGCCTTCTGCCTCAAGGTGCTGACCCGCCAGAG
CTGTGTGTGGGTCAACGGGTTGCCGCTGAGGTACCTGGAGCAGGTTCCCCTGCACTCCGTCAAC
AGAATCTCCTTCTCTGGCATCCAGATGCTCATCCGCAAAGAGGGGGGCGCCTCCCTTGAGGCCT
TTGTCTGCTATTTCCATCTCAGCCCCTCGCCCCTGATTTACAGACCCAAGGCTCAGGAGACAGA
CGAATGAATGGGAAAACACTGTCAAGAAAGAGACTCCCCCTGTTTTGGGGGGAGGCAACTCGTG
ATCTCCTGGGGTCTCTCCACGGCCCCTCCCCGTCTCTGTTTCCCTGCCAAGCCCTGGAGAAGCA
ACAGAAGCAAAGCACCAGAGGAAGCCTCGAGACCCGGCACCCCACCAGCCCCGCTGCGGAGAGC
AAGCCTTACAAAAGCGGGGTTTGAGATGGTTGAGTTACGTCAGAGTTCACATGTAAAGCCTGCT
GGCCGCCATGTTCACAGGGCACGGATTCGGTAAACTTGGAGCGGCCCAGGGACGGAGAAGGGCC
CTTCATGGCTCCAGGGAATGGGAACTTCATATACTTTTAGAGGCCCTGAGGGGTTCTGGGAGCC
CCTCCCAGCATTCTGCCCGCCCCCTCCCCATTTCCTCCCTTGTCTGGCTAGGAGTTACTTTATG
TCCCTCGTCTCCCATGCTGCCTAAGGGCAGGAGCATGGGGTTGCGGCAGGAATGCAAGGACACG
CAAGGAGGAATTACGTTTGTGGTAGCTCGGGGTTACCTTCAGCTTTCAAATACCCACAGGCGCT
CAGGGCTTAGGAGAGCCTGTGTTTAATAAACTAAAAGTATTTCATTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001020200	(Get FASTA)	NCBI Sequence Viewer
	XP_006253640	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH91188	(Get FASTA)	NCBI Sequence Viewer
	EDL93946	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000015878
	ENSRNOP00000015878.3
	ENSRNOP00000083675.1
	ENSRNOP00000087435
GenBank Protein	Q5BK67	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001020200 ⟸ NM_001025029
- UniProtKB:	Q5BK67 (UniProtKB/Swiss-Prot), A6KAN8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MERPLTVLQVSLYHPTQGPVAFAKVPLQLQHDASRLLVGRGQDTHLQLQLPQLSRHHLCLEPYL EKGSNLLAFCLKVLTRQSCVWVNGLPLRYLEQVPLHSVNRISFSGIQMLIRKEGGASLEAFVCY FHLSPSPLIYRPKAQETDE hide sequence

RefSeq Acc Id:	XP_006253640 ⟸ XM_006253578
- Peptide Label:	isoform X1
- UniProtKB:	Q5BK67 (UniProtKB/Swiss-Prot), A6KAN8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MERPLTVLQVSLYHPTQGPVAFAKVPLQLQHDASRLLVGRGQDTHLQLQLPQLSRHHLCLEPYL EKGSNLLAFCLKVLTRQSCVWVNGLPLRYLEQVPLHSVNRISFSGIQMLIRKEGGASLEAFVCY FHLSPSPLIYRPKAQETDE hide sequence

Ensembl Acc Id:

ENSRNOP00000015878 ⟸ ENSRNOT00000015878

Ensembl Acc Id:

ENSRNOP00000083675 ⟸ ENSRNOT00000116729

Ensembl Acc Id:

ENSRNOP00000103745 ⟸ ENSRNOT00000128696

Ensembl Acc Id:

ENSRNOP00000108983 ⟸ ENSRNOT00000167627

Ensembl Acc Id:

ENSRNOP00000111504 ⟸ ENSRNOT00000141048

Ensembl Acc Id:

ENSRNOP00000087435 ⟸ ENSRNOT00000107660

Ensembl Acc Id:

ENSRNOP00000103985 ⟸ ENSRNOT00000145069

Protein Domains

FHA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5BK67-F1-model_v2	AlphaFold	Q5BK67	1-147	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700294

Promoter ID:

EPDNEW_R10817

Type:

multiple initiation site

Name:

Tifab_1

Description:

TIFA inhibitor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	9,236,156 - 9,236,216	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311681	AgrOrtholog
BioCyc Gene	G2FUF-10245	BioCyc
Ensembl Genes	ENSRNOG00000011947	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000015878	ENTREZGENE
	ENSRNOT00000015878.5	UniProtKB/Swiss-Prot
	ENSRNOT00000107660	ENTREZGENE
	ENSRNOT00000116729.1	UniProtKB/Swiss-Prot
Gene3D-CATH	2.60.200.20	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7367314	IMAGE-MGC_LOAD
InterPro	FHA_dom	UniProtKB/Swiss-Prot
	SMAD_FHA_dom_sf	UniProtKB/Swiss-Prot
	TIFA	UniProtKB/Swiss-Prot
KEGG Report	rno:364674	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108845	IMAGE-MGC_LOAD
NCBI Gene	364674	ENTREZGENE
PANTHER	PTHR31266	UniProtKB/Swiss-Prot
	TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN B	UniProtKB/Swiss-Prot
Pfam	FHA	UniProtKB/Swiss-Prot
PhenoGen	Tifab	PhenoGen
RatGTEx	ENSRNOG00000011947	RatGTEx
Superfamily-SCOP	SSF49879	UniProtKB/Swiss-Prot
UniProt	A6KAN8	ENTREZGENE, UniProtKB/TrEMBL
	Q5BK67	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-08	Tifab	TIFA inhibitor	Tifab	TIFA inhibitor B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-02-03	Tifab	TIFA inhibitor B	Tifab	TRAF-interacting protein with forkhead-associated domain, family member B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-31	Tifab	TRAF-interacting protein with forkhead-associated domain, family member B	RGD1311681	similar to MGC37193 protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1311681	similar to MGC37193 protein	RGD1311681_predicted	similar to MGC37193 protein (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1311681_predicted	similar to MGC37193 protein (predicted)	LOC364674_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC364674_predicted	similar to MGC37193 protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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