Gene:	Itk ( Rattus norvegicus ) IL2-inducible T-cell kinase
Synonyms:	Itk_predicted; IL2-inducible T-cell kinase (predicted); LOC363577;
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: ITK     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Itk     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Itk Rat Celera Assembly 10 30206982 - 30266583     RGSC genome assembly v3.4 10 31457709 - 31518059     Cytogenetic 10 q21     genome assembly 3.1 10 31457025 - 31519124 Mus musculus Itk Mouse genome assembly build 36.1 11 46138652 - 46203017     Cytogenetic 11 11 B1.1 Homo sapiens ITK human genome assembly 5 156540484 - 156614687     Human genome assembly build 36.2 5 156540485 - 156614687     Cytogenetic 5 q31-q32   View comparative maps:      NCBI MapViewer
Genome
View:
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Annotation
Molecular Function	Gene Ontology protein binding (details...)
Cellular Component	Gene Ontology cytosol (details...)
External Links
Databases	DATABASE ID SOURCE SMART: TyrKc IPI SMART: BTK IPI SMART: SH2 IPI SMART: PH IPI SMART: SH3 IPI PROSITE: PROTEIN_KINASE_ATP IPI PROSITE: PH_DOMAIN IPI PROSITE: PROTEIN_KINASE_DOM IPI PROSITE: PROTEIN_KINASE_TYR IPI PROSITE: SH2 IPI PROSITE: SH3 IPI PROSITE: ZF_BTK IPI UNIPARC: UPI0000DA3541 IPI UNIPARC: UPI0000DC1A64 IPI KEGG Report: rno:363577 ENTREZGENE HomoloGene Group ID: 4051 ENTREZGENE Germonline: 1311618 Pfam: Pkinase_Tyr IPI Pfam: SH2 IPI Pfam: SH3_1 IPI Pfam: PH IPI Pfam: BTK IPI KEGG Pathway: 04660 ENTREZGENE KEGG Pathway: 04062 ENTREZGENE KEGG Pathway: 04670 ENTREZGENE InterPro: Protein_kinase_ATP_BS. IPI InterPro: Prot_kinase_cat_dom. IPI InterPro: PH_type. IPI InterPro: Kinase-like_dom. IPI InterPro: Pleckstrin_homology. IPI InterPro: SH3_domain. IPI InterPro: Tyr_prot_kinase. IPI InterPro: Tyr_kinase_non-rcpt_ITK/TSK. IPI InterPro: SH2. IPI InterPro: Znf_Btk_motif. IPI InterPro: Tyr_prot_kinase_subgr_cat_dom. IPI InterPro: Tyr_prot_kinase_cat_dom. IPI InterPro: Tyr_prot_kinase_AS. IPI IPI: IPI00781649 IPI IPI: IPI00367793 IPI Ensembl Protein: ENSRNOP00000056245 IPI Ensembl Protein: ENSRNOP00000009211 IPI Gene3D-CATH: PH_type IPI Gene3D-CATH: SH2 IPI Entrez Gene: Itk ENTREZGENE Ensembl Genes: ENSRNOG00000006860 IPI Superfamily-SCOP: Kinase_like IPI Superfamily-SCOP: SH3 IPI PANTHER: Tyr_prot_kinase IPI PANTHER: Tyr_kinase_non-rcpt_ITK/TSK IPI PRINTS: SH2DOMAIN. IPI PRINTS: TECBTKDOMAIN. IPI
Sequences	Nucleotide: NM_001108825 Get FASTA Search GEO Profiles Nucleotide: XM_001068881 Get FASTA Search GEO Profiles Nucleotide: XM_001068937 Get FASTA Search GEO Profiles Nucleotide: CH473948 Get FASTA Search GEO Profiles Nucleotide: XM_343880 Get FASTA Search GEO Profiles (View all 5 Nucleotide Accessions) Protein: XP_343881 Get FASTA Protein: XP_001068937 Get FASTA Protein: XP_001068881 Get FASTA Protein: NP_001102295 Get FASTA Protein: EDM04168 Get FASTA (View all 5 Protein Accessions)
Clusters	UniGene: 145244
References
Curated References	3 references in RGD related to Itk
Database Information
RGD ID	1311618
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 30-APR-08: Itk IL2-inducible T-cell kinase Itk_predicted IL2-inducible T-cell kinase (predicted) APPROVED 'predicted' is removed 2292626 12-JAN-05: Itk_predicted IL2-inducible T-cell kinase (predicted) APPROVED Symbol and Name status set to approved 70820