Cd22 (CD22 molecule) - Rat Genome Database

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Gene: Cd22 (CD22 molecule) Rattus norvegicus
Analyze
Symbol: Cd22
Name: CD22 molecule
RGD ID: 1311610
Description: Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Predicted to be involved in several processes, including negative regulation of immunoglobulin production; negative regulation of signal transduction; and regulation of B cell proliferation. Predicted to be located in cell surface and neuronal cell body membrane. Predicted to be active in early endosome; external side of plasma membrane; and recycling endosome. Human ortholog(s) of this gene implicated in diffuse large B-cell lymphoma. Orthologous to human CD22 (CD22 molecule); PARTICIPATES IN B cell receptor signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: B-cell receptor CD22; CD22 antigen; LOC308501
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,243,785 - 95,270,430 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl195,244,868 - 95,259,730 (-)EnsemblGRCr8
mRatBN7.2186,116,376 - 86,132,782 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,117,459 - 86,132,322 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx191,537,671 - 91,552,509 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,003,840 - 100,018,678 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,295,970 - 93,310,808 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,313,475 - 89,329,902 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,314,558 - 89,329,418 (-)Ensemblrn6Rnor6.0
Rnor_5.0190,468,925 - 90,484,920 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4185,923,707 - 85,938,567 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera180,486,049 - 80,501,174 (-)NCBICelera
RGSC_v3.1186,002,464 - 86,017,095 (-)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bryostatin  (ISO)
bryostatin 1  (ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
cisplatin  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
dexamethasone  (ISO)
dexamethasone phosphate  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
diquat  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
fonofos  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
kojic acid  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (EXP)
mercury dichloride  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nitrates  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
ozone  (EXP,ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sulforaphane  (ISO)
tamibarotene  (ISO)
terbufos  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trametinib  (ISO)
tributylstannane  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Anti-CD22 and anti-CD79B antibody drug conjugates are active in different molecular diffuse large B-cell lymphoma subtypes. Pfeifer M, etal., Leukemia. 2015 Jul;29(7):1578-86. doi: 10.1038/leu.2015.48. Epub 2015 Feb 24.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8418208   PMID:11606382   PMID:12115612   PMID:12477932   PMID:15095367   PMID:17562860   PMID:20200274   PMID:20458337   PMID:24169826   PMID:26017478  


Genomics

Comparative Map Data
Cd22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,243,785 - 95,270,430 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl195,244,868 - 95,259,730 (-)EnsemblGRCr8
mRatBN7.2186,116,376 - 86,132,782 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,117,459 - 86,132,322 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx191,537,671 - 91,552,509 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,003,840 - 100,018,678 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,295,970 - 93,310,808 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,313,475 - 89,329,902 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,314,558 - 89,329,418 (-)Ensemblrn6Rnor6.0
Rnor_5.0190,468,925 - 90,484,920 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4185,923,707 - 85,938,567 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera180,486,049 - 80,501,174 (-)NCBICelera
RGSC_v3.1186,002,464 - 86,017,095 (-)NCBI
Cytogenetic Map1q21NCBI
CD22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,329,187 - 35,347,361 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,319,261 - 35,347,361 (+)Ensemblhg38GRCh38
GRCh371935,820,090 - 35,838,264 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,511,919 - 40,530,104 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341940,511,951 - 40,530,102NCBI
Celera1932,533,518 - 32,551,714 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,328,559 - 32,346,758 (+)NCBIHuRef
CHM1_11935,821,684 - 35,839,873 (+)NCBICHM1_1
T2T-CHM13v2.01937,873,914 - 37,892,093 (+)NCBIT2T-CHM13v2.0
Cd22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,564,829 - 30,579,767 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,564,827 - 30,579,767 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38730,865,404 - 30,880,342 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,865,402 - 30,880,342 (-)Ensemblmm10GRCm38
MGSCv37731,650,423 - 31,665,361 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36730,574,589 - 30,589,027 (-)NCBIMGSCv36mm8
Celera725,448,881 - 25,463,851 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.26NCBI
Cd22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554684,612,044 - 4,625,882 (+)Ensembl
ChiLan1.0NW_0049554684,609,601 - 4,622,601 (+)NCBIChiLan1.0ChiLan1.0
CD22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,337,545 - 41,362,265 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,320,913 - 43,343,681 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,265,278 - 32,294,122 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11941,012,271 - 41,030,719 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1941,012,222 - 41,030,713 (+)EnsemblpanPan2panpan1.1
CD22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,261,730 - 117,285,775 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,261,740 - 117,284,818 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1116,664,704 - 116,687,971 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01117,861,459 - 117,884,944 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,861,538 - 117,902,800 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,424,429 - 117,447,695 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,050,263 - 117,073,530 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01118,105,745 - 118,129,031 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cd22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,673,663 - 10,685,813 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936570960,746 - 969,049 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936570960,592 - 971,688 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl644,820,689 - 44,834,389 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1644,820,593 - 44,834,392 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,344,666 - 40,351,564 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,251,220 - 30,285,084 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl630,270,229 - 30,282,859 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660738,052,288 - 8,074,899 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247948,211,094 - 8,221,866 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247948,211,232 - 8,224,020 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cd22
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12165,136,440 - 165,151,565 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cd22
70 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:104
Count of miRNA genes:75
Interacting mature miRNAs:96
Transcripts:ENSRNOT00000033155
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat

Markers in Region
AI178268  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2186,117,605 - 86,117,805 (+)MAPPERmRatBN7.2
Rnor_6.0189,314,703 - 89,314,902NCBIRnor6.0
Rnor_5.0190,470,153 - 90,470,352UniSTSRnor5.0
RGSC_v3.4185,923,852 - 85,924,051UniSTSRGSC3.4
Celera180,486,194 - 80,486,393UniSTS
RH 3.4 Map1844.4UniSTS
Cytogenetic Map1q21UniSTS
Cd22  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2186,117,561 - 86,117,687 (+)MAPPERmRatBN7.2
Rnor_6.0189,314,659 - 89,314,784NCBIRnor6.0
Rnor_5.0190,470,109 - 90,470,234UniSTSRnor5.0
RGSC_v3.4185,923,808 - 85,923,933UniSTSRGSC3.4
Celera180,486,150 - 80,486,275UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 65 152 91 90 59 92 59 6 351 190 11 128 78 92 31 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000033155   ⟹   ENSRNOP00000031661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,244,868 - 95,259,730 (-)Ensembl
mRatBN7.2 Ensembl186,117,459 - 86,132,322 (-)Ensembl
Rnor_6.0 Ensembl189,314,558 - 89,329,418 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078284   ⟹   ENSRNOP00000069821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl189,314,632 - 89,329,185 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000133006   ⟹   ENSRNOP00000106657
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,244,868 - 95,259,730 (-)Ensembl
RefSeq Acc Id: NM_001107503   ⟹   NP_001100973
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,244,868 - 95,259,730 (-)NCBI
mRatBN7.2186,117,459 - 86,132,322 (-)NCBI
Rnor_6.0189,314,558 - 89,329,418 (-)NCBI
Rnor_5.0190,468,925 - 90,484,920 (-)NCBI
RGSC_v3.4185,923,707 - 85,938,567 (-)RGD
Celera180,486,049 - 80,501,174 (-)RGD
Sequence:
RefSeq Acc Id: XM_006228828   ⟹   XP_006228890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,243,785 - 95,261,855 (-)NCBI
mRatBN7.2186,116,376 - 86,132,781 (-)NCBI
Rnor_6.0189,313,475 - 89,329,902 (-)NCBI
Rnor_5.0190,468,925 - 90,484,920 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008759153   ⟹   XP_008757375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,243,785 - 95,261,855 (-)NCBI
mRatBN7.2186,116,376 - 86,132,781 (-)NCBI
Rnor_6.0189,314,673 - 89,329,487 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008759154   ⟹   XP_008757376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,243,785 - 95,261,855 (-)NCBI
mRatBN7.2186,116,376 - 86,132,781 (-)NCBI
Rnor_6.0189,315,224 - 89,329,487 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039111593   ⟹   XP_038967521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,243,785 - 95,261,855 (-)NCBI
mRatBN7.2186,116,376 - 86,132,781 (-)NCBI
RefSeq Acc Id: XM_039111597   ⟹   XP_038967525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,248,585 - 95,261,857 (-)NCBI
mRatBN7.2186,121,176 - 86,132,782 (-)NCBI
RefSeq Acc Id: XM_063261594   ⟹   XP_063117664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,243,785 - 95,270,430 (-)NCBI
RefSeq Acc Id: XM_063261598   ⟹   XP_063117668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,245,516 - 95,261,856 (-)NCBI
RefSeq Acc Id: XR_005505432
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,243,785 - 95,261,855 (-)NCBI
mRatBN7.2186,116,376 - 86,132,781 (-)NCBI
RefSeq Acc Id: NP_001100973   ⟸   NM_001107503
- Peptide Label: precursor
- UniProtKB: D3ZD88 (UniProtKB/TrEMBL),   A6JA30 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228890   ⟸   XM_006228828
- Peptide Label: isoform X1
- UniProtKB: D3ZD88 (UniProtKB/TrEMBL),   A6JA30 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008757375   ⟸   XM_008759153
- Peptide Label: isoform X1
- UniProtKB: D3ZD88 (UniProtKB/TrEMBL),   A6JA30 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008757376   ⟸   XM_008759154
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000031661   ⟸   ENSRNOT00000033155
Ensembl Acc Id: ENSRNOP00000069821   ⟸   ENSRNOT00000078284
RefSeq Acc Id: XP_038967521   ⟸   XM_039111593
- Peptide Label: isoform X1
- UniProtKB: D3ZD88 (UniProtKB/TrEMBL),   A6JA30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967525   ⟸   XM_039111597
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063117664   ⟸   XM_063261594
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063117668   ⟸   XM_063261598
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000106657   ⟸   ENSRNOT00000133006
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZD88-F1-model_v2 AlphaFold D3ZD88 1-852 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689934
Promoter ID:EPDNEW_R458
Type:multiple initiation site
Name:Cd22_1
Description:CD22 molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0189,329,430 - 89,329,490EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311610 AgrOrtholog
BioCyc Gene G2FUF-60066 BioCyc
Ensembl Genes ENSRNOG00000024000 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000033155 ENTREZGENE
  ENSRNOT00000033155.7 UniProtKB/TrEMBL
  ENSRNOT00000133006 ENTREZGENE
  ENSRNOT00000133006.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_CD22 UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
KEGG Report rno:308501 UniProtKB/TrEMBL
NCBI Gene 308501 ENTREZGENE
PANTHER B-CELL RECEPTOR CD22 UniProtKB/TrEMBL
  B-CELL RECEPTOR CD22 UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  Ig_2 UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  Ig_CD22 UniProtKB/TrEMBL
PhenoGen Cd22 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024000 RatGTEx
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0ABK0LNY7_RAT UniProtKB/TrEMBL
  A6JA30 ENTREZGENE, UniProtKB/TrEMBL
  D3ZD88 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-06-27 Cd22  Cd22 molecule  Cd22  CD22 antigen   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-27 Cd22  CD22 molecule  Cd22  Cd22 molecule  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Cd22  CD22 antigen   Cd22_predicted  CD22 antigen (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cd22_predicted  CD22 antigen (predicted)      Symbol and Name status set to approved 70820 APPROVED