Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PPIP5K1 mRNA | CTD | PMID:22206623 | 2-hydroxypropanoic acid | increases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PPIP5K1 mRNA | CTD | PMID:30851411 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of PPIP5K1 mRNA | CTD | PMID:26251327 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PPIP5K1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PPIP5K1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PPIP5K1 mRNA | CTD | PMID:36041667 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PPIP5K1 mRNA | CTD | PMID:24780913 | acrolein | multiple interactions | ISO | PPIP5K1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of PPIP5K1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of PPIP5K1 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PPIP5K1 mRNA | CTD | PMID:19770486 | alpha-pinene | multiple interactions | ISO | PPIP5K1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of PPIP5K1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of PPIP5K1 mRNA | CTD | PMID:32699268 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of PPIP5K1 gene | CTD | PMID:28931070 | benzo[a]pyrene | affects methylation | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PPIP5K1 5' UTR | CTD | PMID:27901495 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PPIP5K1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PPIP5K1 mRNA | CTD | PMID:38074096 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PPIP5K1 mRNA | CTD | PMID:36041667 | bisphenol A | increases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of PPIP5K1 mRNA | CTD | PMID:26063408 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PPIP5K1 mRNA | CTD | PMID:30816183 more ... | bisphenol F | multiple interactions | ISO | PPIP5K1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PPIP5K1 mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PPIP5K1 mRNA | CTD | PMID:36041667 | caffeine | decreases phosphorylation | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of PPIP5K1 protein | CTD | PMID:35688186 | calcitriol | increases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of PPIP5K1 mRNA | CTD | PMID:26485663 | carbon nanotube | decreases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of PPIP5K1 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | PPIP5K1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PPIP5K1 gene] | CTD | PMID:28238834 | chlordecone | decreases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | Chlordecone results in decreased expression of PPIP5K1 mRNA | CTD | PMID:33711761 | chlorpyrifos | increases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of PPIP5K1 mRNA | CTD | PMID:37019170 | chromium(6+) | affects expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of PPIP5K1 mRNA | CTD | PMID:28472532 | cyclosporin A | increases methylation | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Cyclosporine results in increased methylation of PPIP5K1 promoter | CTD | PMID:27989131 | cyclosporin A | decreases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of PPIP5K1 mRNA | CTD | PMID:19770486 | dexamethasone | multiple interactions | ISO | PPIP5K1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PPIP5K1 mRNA | CTD | PMID:28628672 | doxorubicin | decreases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PPIP5K1 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PPIP5K1 mRNA | CTD | PMID:29391264 | endosulfan | affects expression | EXP | | 6480464 | Endosulfan affects the expression of PPIP5K1 mRNA | CTD | PMID:31464424 | ethanol | multiple interactions | ISO | Ppip5k1 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of PPIP5K1 mRNA | CTD | PMID:30319688 | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PPIP5K1 mRNA | CTD | PMID:22129741 | indometacin | multiple interactions | ISO | PPIP5K1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PPIP5K1 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PPIP5K1 protein | CTD | PMID:32959892 | maneb | multiple interactions | ISO | Ppip5k1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of PPIP5K1 mRNA | CTD | PMID:36117858 | methylmercury chloride | decreases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of PPIP5K1 mRNA | CTD | PMID:28001369 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of PPIP5K1 mRNA | CTD | PMID:28801915 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PPIP5K1 mRNA | CTD | PMID:22129741 | ozone | multiple interactions | ISO | PPIP5K1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of PPIP5K1 mRNA more ... | CTD | PMID:32699268 | paraquat | multiple interactions | ISO | Ppip5k1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of PPIP5K1 mRNA | CTD | PMID:36117858 | rac-lactic acid | increases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PPIP5K1 mRNA | CTD | PMID:30851411 | sodium arsenite | decreases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PPIP5K1 mRNA | CTD | PMID:22714537 | sodium arsenite | increases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PPIP5K1 mRNA | CTD | PMID:29301061 | tert-butyl hydroperoxide | decreases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of PPIP5K1 mRNA | CTD | PMID:15336504 | testosterone | decreases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of PPIP5K1 mRNA | CTD | PMID:33359661 | tetrachloromethane | decreases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of PPIP5K1 mRNA | CTD | PMID:17484886 | titanium dioxide | increases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of PPIP5K1 mRNA | CTD | PMID:23409001 | triptonide | increases expression | ISO | Ppip5k1 (Mus musculus) | 6480464 | triptonide results in increased expression of PPIP5K1 mRNA | CTD | PMID:33045310 | valproic acid | increases expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PPIP5K1 mRNA | CTD | PMID:29154799 | valproic acid | affects expression | ISO | PPIP5K1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PPIP5K1 mRNA | CTD | PMID:25979313 | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of PPIP5K1 gene | CTD | PMID:31682807 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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