Myct1 (myc target 1) - Rat Genome Database

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Gene: Myct1 (myc target 1) Rattus norvegicus
Analyze
Symbol: Myct1
Name: myc target 1
RGD ID: 1311467
Description: Predicted to act upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in nuclear body. Predicted to be active in nucleoplasm. Orthologous to human MYCT1 (MYC target 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amitrole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC292264; myc target protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8144,423,478 - 44,434,751 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl144,423,544 - 44,436,992 (+)EnsemblGRCr8
mRatBN7.2142,018,137 - 42,029,410 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl142,018,137 - 42,029,410 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx142,552,281 - 42,563,568 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0148,539,477 - 48,550,764 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0142,627,778 - 42,639,064 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0142,121,572 - 42,132,131 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl142,121,636 - 42,131,547 (+)Ensemblrn6Rnor6.0
Rnor_5.0143,450,903 - 43,461,462 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4136,314,335 - 36,325,608 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera137,696,838 - 37,707,781 (+)NCBICelera
RGSC_v3.1136,317,334 - 36,327,965 (+)NCBI
Cytogenetic Map1q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
amitrole  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
clotrimazole  (EXP)
decabromodiphenyl ether  (EXP)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
diquat  (ISO)
dopamine  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fenoldopam  (EXP)
hydrogen cyanide  (ISO)
lithium chloride  (ISO)
mercury dibromide  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
panobinostat  (ISO)
phenylmercury acetate  (ISO)
potassium cyanide  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
prothioconazole  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triadimefon  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
yohimbine  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16365299  


Genomics

Comparative Map Data
Myct1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8144,423,478 - 44,434,751 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl144,423,544 - 44,436,992 (+)EnsemblGRCr8
mRatBN7.2142,018,137 - 42,029,410 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl142,018,137 - 42,029,410 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx142,552,281 - 42,563,568 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0148,539,477 - 48,550,764 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0142,627,778 - 42,639,064 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0142,121,572 - 42,132,131 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl142,121,636 - 42,131,547 (+)Ensemblrn6Rnor6.0
Rnor_5.0143,450,903 - 43,461,462 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4136,314,335 - 36,325,608 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera137,696,838 - 37,707,781 (+)NCBICelera
RGSC_v3.1136,317,334 - 36,327,965 (+)NCBI
Cytogenetic Map1q11NCBI
MYCT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386152,697,897 - 152,747,181 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6152,697,897 - 152,724,569 (+)Ensemblhg38GRCh38
GRCh376153,019,032 - 153,049,320 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366153,060,723 - 153,087,410 (+)NCBIBuild 36Build 36hg18NCBI36
Build 346153,111,151 - 153,135,872NCBI
Celera6153,752,735 - 153,779,422 (+)NCBICelera
Cytogenetic Map6q25.2NCBI
HuRef6150,582,149 - 150,608,836 (+)NCBIHuRef
CHM1_16153,282,995 - 153,309,668 (+)NCBICHM1_1
T2T-CHM13v2.06153,899,213 - 153,948,502 (+)NCBIT2T-CHM13v2.0
Myct1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39105,543,728 - 5,556,789 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl105,543,775 - 5,556,904 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38105,593,728 - 5,606,789 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl105,593,775 - 5,606,904 (+)Ensemblmm10GRCm38
MGSCv37104,739,752 - 4,752,813 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36104,740,985 - 4,752,760 (-)NCBIMGSCv36mm8
Celera105,530,674 - 5,543,682 (+)NCBICelera
Cytogenetic Map10A1NCBI
cM Map101.99NCBI
Myct1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554399,065,574 - 9,086,539 (-)Ensembl
ChiLan1.0NW_0049554399,065,983 - 9,086,491 (-)NCBIChiLan1.0ChiLan1.0
MYCT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25172,722,140 - 172,745,154 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16170,614,972 - 170,637,991 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06150,515,673 - 150,538,481 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16155,205,805 - 155,228,622 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6155,205,805 - 155,228,622 (+)EnsemblpanPan2panpan1.1
MYCT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1142,886,997 - 42,908,813 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl142,830,099 - 42,925,680 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha143,725,891 - 43,747,707 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0143,071,520 - 43,093,369 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl143,049,590 - 43,093,349 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1142,943,635 - 42,965,448 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0142,807,264 - 42,829,075 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0143,295,123 - 43,316,929 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Myct1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946138,119,917 - 138,148,617 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364895,371,934 - 5,400,229 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364895,371,910 - 5,400,610 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYCT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl113,651,399 - 13,667,284 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1113,651,397 - 13,667,210 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2115,946,514 - 15,970,725 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYCT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11380,167,974 - 80,192,976 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1380,168,447 - 80,193,110 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604052,499,529 - 52,523,359 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myct1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247855,543,855 - 5,570,774 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247855,543,867 - 5,570,727 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Myct1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12197,230,492 - 197,241,589 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Myct1
117 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:349
Count of miRNA genes:212
Interacting mature miRNAs:250
Transcripts:ENSRNOT00000025616
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat

Markers in Region
RH130503  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2142,028,642 - 42,028,796 (+)MAPPERmRatBN7.2
Rnor_6.0142,131,364 - 42,131,517NCBIRnor6.0
Rnor_5.0143,460,695 - 43,460,848UniSTSRnor5.0
RGSC_v3.4136,324,841 - 36,324,994UniSTSRGSC3.4
Celera137,707,014 - 37,707,167UniSTS
Cytogenetic Map1p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 67 135 91 90 59 89 59 6 349 189 11 109 78 91 31 4 4

Sequence


Ensembl Acc Id: ENSRNOT00000025616   ⟹   ENSRNOP00000025616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl144,423,544 - 44,436,992 (+)Ensembl
mRatBN7.2 Ensembl142,018,137 - 42,029,410 (+)Ensembl
Rnor_6.0 Ensembl142,121,636 - 42,131,547 (+)Ensembl
RefSeq Acc Id: NM_001106207   ⟹   NP_001099677
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8144,423,478 - 44,434,751 (+)NCBI
mRatBN7.2142,018,137 - 42,029,410 (+)NCBI
Rnor_6.0142,121,572 - 42,132,131 (+)NCBI
Rnor_5.0143,450,903 - 43,461,462 (+)NCBI
RGSC_v3.4136,314,335 - 36,325,608 (+)RGD
Celera137,696,838 - 37,707,781 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099677 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL92842 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025616
  ENSRNOP00000025616.5
RefSeq Acc Id: NP_001099677   ⟸   NM_001106207
- UniProtKB: D3ZUL5 (UniProtKB/TrEMBL),   A6KIN7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025616   ⟸   ENSRNOT00000025616

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZUL5-F1-model_v2 AlphaFold D3ZUL5 1-188 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689589
Promoter ID:EPDNEW_R114
Type:multiple initiation site
Name:Myct1_1
Description:myc target 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0142,121,624 - 42,121,684EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311467 AgrOrtholog
BioCyc Gene G2FUF-61703 BioCyc
Ensembl Genes ENSRNOG00000018858 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025616 ENTREZGENE
  ENSRNOT00000025616.9 UniProtKB/TrEMBL
InterPro Myc_target_1 UniProtKB/TrEMBL
KEGG Report rno:292264 UniProtKB/TrEMBL
NCBI Gene 292264 ENTREZGENE
PANTHER MYC TARGET PROTEIN 1 UniProtKB/TrEMBL
  PTHR14869 UniProtKB/TrEMBL
Pfam Myc_target_1 UniProtKB/TrEMBL
PhenoGen Myct1 PhenoGen
RatGTEx ENSRNOG00000018858 RatGTEx
UniProt A6KIN7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZUL5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Myct1  myc target 1   Myct1_predicted  myc target 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Myct1_predicted  myc target 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED