Snorc (secondary ossification center associated regulator of chondrocyte maturation) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Snorc (secondary ossification center associated regulator of chondrocyte maturation) Rattus norvegicus
Analyze
Symbol: Snorc
Name: secondary ossification center associated regulator of chondrocyte maturation
RGD ID: 1311447
Description: Predicted to be involved in cartilage development. Predicted to be located in collagen-containing extracellular matrix. Orthologous to human SNORC (secondary ossification center associated regulator of chondrocyte maturation); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC363276; LOC363276; RGD1311447; uncharacterized protein C2orf82 homolog; uncharacterized protein LOC363276
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,574,943 - 95,593,394 (+)NCBIGRCr8
mRatBN7.2988,140,510 - 88,145,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,140,419 - 88,145,891 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx996,564,757 - 96,570,235 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,700,837 - 101,706,315 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09100,068,665 - 100,074,137 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,562,839 - 94,568,312 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,562,839 - 94,568,312 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,277,428 - 94,289,755 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,287,756 - 86,293,229 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1986,471,177 - 86,476,283 (+)NCBI
Celera985,550,052 - 85,555,522 (+)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21624478   PMID:28323137   PMID:32385306  


Genomics

Comparative Map Data
Snorc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,574,943 - 95,593,394 (+)NCBIGRCr8
mRatBN7.2988,140,510 - 88,145,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,140,419 - 88,145,891 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx996,564,757 - 96,570,235 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,700,837 - 101,706,315 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09100,068,665 - 100,074,137 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,562,839 - 94,568,312 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,562,839 - 94,568,312 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,277,428 - 94,289,755 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,287,756 - 86,293,229 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1986,471,177 - 86,476,283 (+)NCBI
Celera985,550,052 - 85,555,522 (+)NCBICelera
Cytogenetic Map9q35NCBI
SNORC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382232,866,451 - 232,878,700 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2232,857,270 - 232,878,708 (+)EnsemblGRCh38hg38GRCh38
GRCh372233,731,161 - 233,743,410 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,443,238 - 233,449,351 (+)NCBINCBI36Build 36hg18NCBI36
Celera2227,499,270 - 227,505,383 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2225,583,855 - 225,589,964 (+)NCBIHuRef
CHM1_12233,740,922 - 233,747,035 (+)NCBICHM1_1
T2T-CHM13v2.02233,353,135 - 233,365,383 (+)NCBIT2T-CHM13v2.0
Snorc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,397,734 - 87,403,204 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,397,993 - 87,403,204 (+)EnsemblGRCm39 Ensembl
GRCm38187,470,201 - 87,475,482 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,470,271 - 87,475,482 (+)EnsemblGRCm38mm10GRCm38
MGSCv37189,366,839 - 89,372,034 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36189,301,372 - 89,306,653 (+)NCBIMGSCv36mm8
Celera190,435,932 - 90,441,129 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map144.41NCBI
Snorc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554533,187,672 - 3,191,662 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554533,187,624 - 3,192,605 (-)NCBIChiLan1.0ChiLan1.0
SNORC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213135,474,611 - 135,484,280 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B135,489,583 - 135,499,243 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B120,100,778 - 120,110,444 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B239,017,916 - 239,027,304 (+)NCBIpanpan1.1PanPan1.1panPan2
SNORC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,453,804 - 44,472,159 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,466,852 - 44,470,935 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2544,946,062 - 44,968,021 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02544,724,351 - 44,731,525 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2544,723,832 - 44,731,461 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12544,634,688 - 44,656,607 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02544,480,719 - 44,502,706 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02544,635,988 - 44,657,916 (+)NCBIUU_Cfam_GSD_1.0
Snorc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303186,649,054 - 186,655,570 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365254,284,203 - 4,290,428 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365254,284,176 - 4,290,384 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNORC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,323,562 - 133,330,253 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115133,323,562 - 133,330,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215147,324,526 - 147,331,222 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SNORC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110118,901,596 - 118,908,465 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10118,902,349 - 118,908,530 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604080,599,859 - 80,600,910 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snorc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248435,552,042 - 5,556,262 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248435,551,945 - 5,556,269 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Snorc
22 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:68
Count of miRNA genes:57
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000022308
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)98636963192058970Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 13 8 4 7 4 49 13 32 9
Below cutoff 28 36 27 11 27 1 3 22 18 9 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000022308   ⟹   ENSRNOP00000022308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl988,140,419 - 88,145,891 (+)Ensembl
Rnor_6.0 Ensembl994,562,839 - 94,568,312 (+)Ensembl
RefSeq Acc Id: NM_001413910   ⟹   NP_001400839
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,588,377 - 95,593,394 (+)NCBI
mRatBN7.2988,140,510 - 88,145,527 (+)NCBI
RefSeq Acc Id: XM_006245417   ⟹   XP_006245479
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,574,943 - 95,593,394 (+)NCBI
mRatBN7.2988,140,514 - 88,145,527 (+)NCBI
Rnor_6.0994,562,982 - 94,567,947 (+)NCBI
Rnor_5.0994,277,428 - 94,289,755 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001400839 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245479 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AIY67794 (Get FASTA)   NCBI Sequence Viewer  
  EDL75639 (Get FASTA)   NCBI Sequence Viewer  
  EDL75640 (Get FASTA)   NCBI Sequence Viewer  
  EDL75641 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022308.4
Reference Protein Sequences
RefSeq Acc Id: XP_006245479   ⟸   XM_006245417
- Peptide Label: isoform X1
- UniProtKB: A6JWN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000022308   ⟸   ENSRNOT00000022308
RefSeq Acc Id: NP_001400839   ⟸   NM_001413910
- Peptide Label: precursor
- UniProtKB: A0A0A7ENV2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZLD3-F1-model_v2 AlphaFold D3ZLD3 1-129 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311447 AgrOrtholog
BioCyc Gene G2FUF-26841 BioCyc
Ensembl Genes ENSRNOG00000016606 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022308.6 UniProtKB/TrEMBL
InterPro SNORC UniProtKB/TrEMBL
KEGG Report rno:363276 UniProtKB/TrEMBL
NCBI Gene 363276 ENTREZGENE
PANTHER PROTEIN SNORC UniProtKB/TrEMBL
  PROTEIN SNORC UniProtKB/TrEMBL
Pfam DUF4690 UniProtKB/TrEMBL
PhenoGen Snorc PhenoGen
RatGTEx ENSRNOG00000016606 RatGTEx
UniProt A0A0A7ENV2 ENTREZGENE, UniProtKB/TrEMBL
  A6JWN2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZLD3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-12-22 Snorc  secondary ossification center associated regulator of chondrocyte maturation  RGD1311447  LOC363276  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1311447  LOC363276   RGD1311447_predicted  LOC363276 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1311447_predicted  LOC363276 (predicted)  LOC363276_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC363276_predicted  LOC363276 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL