Snorc (secondary ossification center associated regulator of chondrocyte maturation) - Rat Genome Database

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Gene: Snorc (secondary ossification center associated regulator of chondrocyte maturation) Rattus norvegicus
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Symbol: Snorc
Name: secondary ossification center associated regulator of chondrocyte maturation
RGD ID: 1311447
Description: Predicted to be involved in cartilage development. Predicted to be located in cell periphery. Orthologous to human SNORC (secondary ossification center associated regulator of chondrocyte maturation); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC363276; LOC363276; RGD1311447; uncharacterized protein C2orf82 homolog; uncharacterized protein LOC363276
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,574,943 - 95,593,394 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl995,591,796 - 95,593,394 (+)EnsemblGRCr8
mRatBN7.2988,140,510 - 88,145,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,140,419 - 88,145,891 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx996,564,757 - 96,570,235 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,700,837 - 101,706,315 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09100,068,665 - 100,074,137 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,562,839 - 94,568,312 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,562,839 - 94,568,312 (+)Ensemblrn6Rnor6.0
Rnor_5.0994,277,428 - 94,289,755 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4986,287,756 - 86,293,229 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera985,550,052 - 85,555,522 (+)NCBICelera
RGSC_v3.1986,471,177 - 86,476,283 (+)NCBI
Cytogenetic Map9q35NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21624478   PMID:28323137   PMID:32385306  


Genomics

Comparative Map Data
Snorc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,574,943 - 95,593,394 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl995,591,796 - 95,593,394 (+)EnsemblGRCr8
mRatBN7.2988,140,510 - 88,145,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,140,419 - 88,145,891 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx996,564,757 - 96,570,235 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,700,837 - 101,706,315 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09100,068,665 - 100,074,137 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,562,839 - 94,568,312 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,562,839 - 94,568,312 (+)Ensemblrn6Rnor6.0
Rnor_5.0994,277,428 - 94,289,755 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4986,287,756 - 86,293,229 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera985,550,052 - 85,555,522 (+)NCBICelera
RGSC_v3.1986,471,177 - 86,476,283 (+)NCBI
Cytogenetic Map9q35NCBI
SNORC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382232,866,451 - 232,878,700 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2232,857,270 - 232,878,708 (+)Ensemblhg38GRCh38
GRCh372233,731,161 - 233,743,410 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,443,238 - 233,449,351 (+)NCBIBuild 36Build 36hg18NCBI36
Celera2227,499,270 - 227,505,383 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2225,583,855 - 225,589,964 (+)NCBIHuRef
CHM1_12233,740,922 - 233,747,035 (+)NCBICHM1_1
T2T-CHM13v2.02233,353,135 - 233,365,383 (+)NCBIT2T-CHM13v2.0
Snorc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,397,734 - 87,403,204 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,397,993 - 87,403,204 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38187,470,201 - 87,475,482 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,470,271 - 87,475,482 (+)Ensemblmm10GRCm38
MGSCv37189,366,839 - 89,372,034 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36189,301,372 - 89,306,653 (+)NCBIMGSCv36mm8
Celera190,435,932 - 90,441,129 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map144.41NCBI
Snorc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554533,187,672 - 3,191,662 (-)Ensembl
ChiLan1.0NW_0049554533,187,624 - 3,192,605 (-)NCBIChiLan1.0ChiLan1.0
SNORC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213135,474,611 - 135,484,280 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B135,489,583 - 135,499,243 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B120,100,778 - 120,110,444 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B239,017,916 - 239,027,304 (+)NCBIPanPan1.1PanPan1.1panPan2
SNORC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,453,804 - 44,472,159 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,466,852 - 44,470,935 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2544,946,062 - 44,968,021 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02544,724,351 - 44,731,525 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2544,723,832 - 44,731,461 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12544,634,688 - 44,656,607 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02544,480,719 - 44,502,706 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02544,635,988 - 44,657,916 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Snorc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303186,649,054 - 186,655,570 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365254,284,203 - 4,290,428 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365254,284,176 - 4,290,384 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNORC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,323,562 - 133,330,253 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115133,323,562 - 133,330,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215147,324,526 - 147,331,222 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SNORC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110118,901,596 - 118,908,465 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10118,902,349 - 118,908,530 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604080,599,859 - 80,600,910 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snorc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248435,552,042 - 5,556,262 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248435,551,945 - 5,556,269 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Snorc
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14159,597,437 - 159,600,008 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Snorc
436 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:68
Count of miRNA genes:57
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000022308
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)986720043110356905Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)985262459109044727Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 4 60 153 73 75 44 87 44 6 301 174 11 135 66 92 31 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000022308   ⟹   ENSRNOP00000022308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl988,140,419 - 88,145,891 (+)Ensembl
Rnor_6.0 Ensembl994,562,839 - 94,568,312 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000135286   ⟹   ENSRNOP00000105105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl995,591,796 - 95,593,394 (+)Ensembl
RefSeq Acc Id: NM_001413910   ⟹   NP_001400839
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,588,377 - 95,593,394 (+)NCBI
mRatBN7.2988,140,510 - 88,145,527 (+)NCBI
RefSeq Acc Id: XM_006245417   ⟹   XP_006245479
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,574,943 - 95,593,394 (+)NCBI
mRatBN7.2988,140,514 - 88,145,527 (+)NCBI
Rnor_6.0994,562,982 - 94,567,947 (+)NCBI
Rnor_5.0994,277,428 - 94,289,755 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001400839 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245479 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AIY67794 (Get FASTA)   NCBI Sequence Viewer  
  EDL75639 (Get FASTA)   NCBI Sequence Viewer  
  EDL75640 (Get FASTA)   NCBI Sequence Viewer  
  EDL75641 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000105105
  ENSRNOP00000105105.1
RefSeq Acc Id: XP_006245479   ⟸   XM_006245417
- Peptide Label: isoform X1
- UniProtKB: A6JWN2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022308   ⟸   ENSRNOT00000022308
RefSeq Acc Id: NP_001400839   ⟸   NM_001413910
- Peptide Label: precursor
- UniProtKB: A0A0A7ENV2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105105   ⟸   ENSRNOT00000135286

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZLD3-F1-model_v2 AlphaFold D3ZLD3 1-129 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311447 AgrOrtholog
BioCyc Gene G2FUF-26841 BioCyc
Ensembl Genes ENSRNOG00000016606 Ensembl
  ENSRNOG00000084451 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000135286 ENTREZGENE
  ENSRNOT00000135286.1 UniProtKB/TrEMBL
InterPro SNORC UniProtKB/TrEMBL
NCBI Gene 363276 ENTREZGENE
PANTHER PROTEIN SNORC UniProtKB/TrEMBL
  PROTEIN SNORC UniProtKB/TrEMBL
Pfam DUF4690 UniProtKB/TrEMBL
PhenoGen Snorc PhenoGen
RatGTEx ENSRNOG00000016606 RatGTEx
  ENSRNOG00000084451 RatGTEx
UniProt A0A0A7ENV2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LSS7_RAT UniProtKB/TrEMBL
  A6JWN2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-12-22 Snorc  secondary ossification center associated regulator of chondrocyte maturation  RGD1311447  LOC363276  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1311447  LOC363276   RGD1311447_predicted  LOC363276 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1311447_predicted  LOC363276 (predicted)  LOC363276_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC363276_predicted  LOC363276 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL