Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Kirrel3 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of KIRREL3 mRNA | CTD | PMID:26496021 | Kirrel3 | Rat | 17beta-estradiol | increases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | Estradiol results in increased expression of KIRREL3 mRNA | CTD | PMID:39298647 | Kirrel3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KIRREL3 mRNA | CTD | PMID:32109520 | Kirrel3 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of KIRREL3 mRNA | CTD | PMID:32109520 | Kirrel3 | Rat | 2-palmitoylglycerol | increases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of KIRREL3 mRNA | CTD | PMID:37199045 | Kirrel3 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of KIRREL3 mRNA | CTD | PMID:25172293 | Kirrel3 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression more ... | CTD | PMID:28628672 | Kirrel3 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | Kirrel3 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of KIRREL3 exon | CTD | PMID:33297965 | Kirrel3 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | KIRREL3 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of KIRREL3 gene | CTD | PMID:31601247 | Kirrel3 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of KIRREL3 mRNA | CTD | PMID:24780913 | Kirrel3 | Rat | 8-Br-cAMP | increases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of KIRREL3 mRNA | CTD | PMID:22079614 | Kirrel3 | Rat | aflatoxin B1 | increases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of KIRREL3 mRNA | CTD | PMID:22100608 | Kirrel3 | Rat | aflatoxin B1 | increases methylation | ISO | KIRREL3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of KIRREL3 intron | CTD | PMID:30157460 | Kirrel3 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | KIRREL3 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of KIRREL3 exon; aflatoxin B2 results in decreased methylation more ... | CTD | PMID:30157460 | Kirrel3 | Rat | arsane | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Kirrel3 | Rat | arsenic atom | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Kirrel3 | Rat | atrazine | increases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | Atrazine results in increased expression of KIRREL3 mRNA | CTD | PMID:22378314 | Kirrel3 | Rat | benzo[a]pyrene | decreases methylation | ISO | KIRREL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of KIRREL3 3' UTR; Benzo(a)pyrene results in decreased methylation of more ... | CTD | PMID:27901495 | Kirrel3 | Rat | benzo[a]pyrene | affects methylation | ISO | KIRREL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of KIRREL3 exon; Benzo(a)pyrene affects the methylation of KIRREL3 intron | CTD | PMID:30157460 | Kirrel3 | Rat | benzo[a]pyrene | increases methylation | ISO | KIRREL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of KIRREL3 promoter | CTD | PMID:27901495 | Kirrel3 | Rat | benzo[e]pyrene | increases methylation | ISO | KIRREL3 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of KIRREL3 intron | CTD | PMID:30157460 | Kirrel3 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of KIRREL3 mRNA | CTD | PMID:31163220 | Kirrel3 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in decreased expression of KIRREL3 mRNA | CTD | PMID:33789034 | Kirrel3 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of KIRREL3 gene | CTD | PMID:28505145 | Kirrel3 | Rat | bisphenol A | decreases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of KIRREL3 mRNA | CTD | PMID:32156529 | Kirrel3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of KIRREL3 mRNA | CTD | PMID:34947998 | Kirrel3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of KIRREL3 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016 | Kirrel3 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of KIRREL3 mRNA | CTD | PMID:26496021 | Kirrel3 | Rat | bromobenzene | decreases expression | EXP | | 6480464 | bromobenzene results in decreased expression of KIRREL3 mRNA | CTD | PMID:32479839 | Kirrel3 | Rat | Butylbenzyl phthalate | increases methylation | ISO | Kirrel3 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of KIRREL3 intron | CTD | PMID:28392331 | Kirrel3 | Rat | cadmium atom | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KIRREL3 more ... | CTD | PMID:35301059 | Kirrel3 | Rat | cadmium atom | multiple interactions | ISO | Kirrel3 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KIRREL3 more ... | CTD | PMID:37325564 | Kirrel3 | Rat | cadmium dichloride | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KIRREL3 more ... | CTD | PMID:35301059 | Kirrel3 | Rat | cadmium dichloride | multiple interactions | ISO | Kirrel3 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KIRREL3 more ... | CTD | PMID:37325564 | Kirrel3 | Rat | carbamazepine | affects expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of KIRREL3 mRNA | CTD | PMID:25979313 | Kirrel3 | Rat | casticin | decreases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | casticin results in decreased expression of KIRREL3 mRNA | CTD | PMID:28444820 | Kirrel3 | Rat | CGP 52608 | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to KIRREL3 gene] | CTD | PMID:28238834 | Kirrel3 | Rat | chlorpyrifos | increases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of KIRREL3 mRNA | CTD | PMID:37019170 | Kirrel3 | Rat | chromium(6+) | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression more ... | CTD | PMID:38479592 | Kirrel3 | Rat | cisplatin | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of KIRREL3 mRNA | CTD | PMID:27392435 | Kirrel3 | Rat | cisplatin | decreases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of KIRREL3 mRNA | CTD | PMID:27392435|PMID:27594783 | Kirrel3 | Rat | cocaine | increases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | Cocaine results in increased expression of KIRREL3 mRNA | CTD | PMID:18355967 | Kirrel3 | Rat | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of KIRREL3 mRNA | CTD | PMID:26033743 | Kirrel3 | Rat | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of KIRREL3 mRNA | CTD | PMID:26033743 | Kirrel3 | Rat | crocidolite asbestos | increases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in increased expression of KIRREL3 mRNA | CTD | PMID:29279043 | Kirrel3 | Rat | dexamethasone | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression more ... | CTD | PMID:28628672 | Kirrel3 | Rat | dorsomorphin | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Kirrel3 | Rat | folic acid | decreases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of KIRREL3 mRNA | CTD | PMID:25629700 | Kirrel3 | Rat | indometacin | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression more ... | CTD | PMID:28628672 | Kirrel3 | Rat | lead diacetate | increases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | lead acetate results in increased expression of KIRREL3 mRNA | CTD | PMID:20542052 | Kirrel3 | Rat | lipopolysaccharide | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of KIRREL3 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... | CTD | PMID:35811015 | Kirrel3 | Rat | lipopolysaccharide | decreases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of KIRREL3 mRNA | CTD | PMID:35811015 | Kirrel3 | Rat | manganese atom | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Kirrel3 | Rat | manganese(0) | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Kirrel3 | Rat | manganese(II) chloride | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Kirrel3 | Rat | methapyrilene | increases methylation | ISO | KIRREL3 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of KIRREL3 intron | CTD | PMID:30157460 | Kirrel3 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of KIRREL3 gene | CTD | PMID:35440735 | Kirrel3 | Rat | monosodium L-glutamate | increases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | Sodium Glutamate results in increased expression of KIRREL3 mRNA | CTD | PMID:22078008 | Kirrel3 | Rat | nickel sulfate | decreases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of KIRREL3 mRNA | CTD | PMID:22714537 | Kirrel3 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of KIRREL3 mRNA | CTD | PMID:30723492 | Kirrel3 | Rat | perfluorooctane-1-sulfonic acid | affects expression | ISO | Kirrel3 (Mus musculus) | 6480464 | perfluorooctane sulfonic acid affects the expression of KIRREL3 mRNA | CTD | PMID:19429403 | Kirrel3 | Rat | perfluorooctanoic acid | affects expression | ISO | Kirrel3 (Mus musculus) | 6480464 | perfluorooctanoic acid affects the expression of KIRREL3 mRNA | CTD | PMID:19429403 | Kirrel3 | Rat | potassium bromate | decreases expression | EXP | | 6480464 | potassium bromate results in decreased expression of KIRREL3 mRNA | CTD | PMID:23588252 | Kirrel3 | Rat | propanal | increases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of KIRREL3 mRNA | CTD | PMID:26079696 | Kirrel3 | Rat | rifampicin | decreases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | Rifampin results in decreased expression of KIRREL3 mRNA | CTD | PMID:24552687 | Kirrel3 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of KIRREL3 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... | CTD | PMID:35811015 | Kirrel3 | Rat | SB 431542 | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Kirrel3 | Rat | silicon dioxide | increases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of KIRREL3 mRNA | CTD | PMID:25895662 | Kirrel3 | Rat | sodium arsenite | affects methylation | ISO | KIRREL3 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of KIRREL3 gene | CTD | PMID:28589171 | Kirrel3 | Rat | sodium arsenite | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Kirrel3 | Rat | sodium arsenite | increases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of KIRREL3 mRNA | CTD | PMID:29301061 | Kirrel3 | Rat | testosterone | decreases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | Testosterone results in decreased expression of KIRREL3 mRNA | CTD | PMID:19693291 | Kirrel3 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of KIRREL3 mRNA | CTD | PMID:34492290 | Kirrel3 | Rat | thiram | decreases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | Thiram results in decreased expression of KIRREL3 mRNA | CTD | PMID:38568856 | Kirrel3 | Rat | titanium dioxide | increases expression | ISO | Kirrel3 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of KIRREL3 mRNA | CTD | PMID:35295148 | Kirrel3 | Rat | titanium dioxide | decreases methylation | ISO | Kirrel3 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of KIRREL3 gene | CTD | PMID:35295148 | Kirrel3 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of KIRREL3 mRNA | CTD | PMID:33387578 | Kirrel3 | Rat | trichostatin A | increases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of KIRREL3 mRNA | CTD | PMID:24935251 | Kirrel3 | Rat | valproic acid | multiple interactions | ISO | KIRREL3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Kirrel3 | Rat | valproic acid | increases expression | ISO | KIRREL3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of KIRREL3 mRNA | CTD | PMID:23179753|PMID:24383497|PMID:26272509|PMID:27188386 | Kirrel3 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of KIRREL3 mRNA | CTD | PMID:19015723 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















