Mmp19 (matrix metallopeptidase 19) - Rat Genome Database

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Gene: Mmp19 (matrix metallopeptidase 19) Rattus norvegicus
Analyze
Symbol: Mmp19
Name: matrix metallopeptidase 19
RGD ID: 1311376
Description: Predicted to enable metalloendopeptidase activity. Involved in female gonad development; response to cAMP; and response to hormone. Predicted to be located in extracellular matrix. Orthologous to human MMP19 (matrix metallopeptidase 19); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC304608; matrix metalloproteinase 19; matrix metalloproteinase-19; MMP-19
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,805,732 - 1,814,054 (+)NCBIGRCr8
mRatBN7.271,221,229 - 1,229,555 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl71,221,343 - 1,229,555 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,984,499 - 3,992,199 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,860,160 - 5,867,860 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.076,157,051 - 6,164,751 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.073,216,392 - 3,224,202 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl73,216,497 - 3,224,201 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,187,758 - 3,195,773 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.472,091,532 - 2,099,235 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.172,091,513 - 2,098,874 (+)NCBI
Celera71,092,107 - 1,099,811 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp19RatCOVID-19  ISOMMP19 (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Mmp19Ratobesity  ISOMmp19 (Mus musculus)1642022 RGD 
Mmp19Ratobesity  ISOMmp19 (Mus musculus)1642023mRNA:increased expression:adipose tissueRGD 
Mmp19Ratrelapsing-remitting multiple sclerosis  ISOMMP19 (Homo sapiens)1642025mRNA:increased expression:mononuclear cellRGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp19RatCavitary Optic Disc Anomalies  ISOMMP19 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10764862 more ...
Mmp19Ratinterstitial lung disease 2  ISOMMP19 (Homo sapiens)8554872ClinVar Annotator: match by term: Interstitial lung disease 2ClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp19RatCavitary Optic Disc Anomalies  ISOMMP19 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Mmp19RatSpontaneous Abortions  ISOMMP19 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18539642
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp19RatCavitary Optic Disc Anomalies  ISOMMP19 (Homo sapiens)7240710 OMIM 

1 to 20 of 93 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp19Rat1,1,1-trichloroethane decreases expressionISOMmp19 (Mus musculus)64804641 more ...CTDPMID:25270620
Mmp19Rat1,2-dimethylhydrazine multiple interactionsISOMmp19 (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of MMP19 mRNA]CTDPMID:22206623
Mmp19Rat1,2-dimethylhydrazine decreases expressionISOMmp19 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of MMP19 mRNACTDPMID:22206623
Mmp19Rat17beta-estradiol multiple interactionsISOMMP19 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of MMP19 mRNACTDPMID:30165855
Mmp19Rat17beta-estradiol decreases expressionISOMMP19 (Homo sapiens)6480464Estradiol results in decreased expression of MMP19 mRNACTDPMID:31614463
Mmp19Rat2,2',4,4'-Tetrabromodiphenyl ether increases expressionISOMMP19 (Homo sapiens)64804642 more ...CTDPMID:23146750
Mmp19Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOMMP19 (Homo sapiens)64804642 more ...CTDPMID:31675489
Mmp19Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOMmp19 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of MMP19 mRNACTDPMID:16962184
Mmp19Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of MMP19 mRNACTDPMID:33387578
Mmp19Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOMMP19 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of MMP19 mRNACTDPMID:22574217
Mmp19Rat2,4,6-tribromophenol increases expressionISOMMP19 (Homo sapiens)64804642 more ...CTDPMID:31675489
Mmp19Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of MMP19 mRNACTDPMID:21346803
Mmp19Rat3,3',5,5'-tetrabromobisphenol A increases expressionISOMmp19 (Mus musculus)6480464tetrabromobisphenol A results in increased expression of MMP19 mRNACTDPMID:25172293
Mmp19Rat3,3',5,5'-tetrabromobisphenol A increases expressionISOMMP19 (Homo sapiens)6480464tetrabromobisphenol A results in increased expression of MMP19 proteinCTDPMID:31675489
Mmp19Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOMMP19 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MMP19 mRNA more ...CTDPMID:28628672
Mmp19Rat4,4'-diaminodiphenylmethane increases expressionISOMmp19 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in increased expression of MMP19 mRNACTDPMID:18648102
Mmp19Rat4,4'-sulfonyldiphenol multiple interactionsISOMMP19 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] affects the expression of MMP19 mRNACTDPMID:28628672
Mmp19Rat4-hydroxyphenyl retinamide decreases expressionISOMmp19 (Mus musculus)6480464Fenretinide results in decreased expression of MMP19 mRNACTDPMID:28973697
Mmp19Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of MMP19 mRNACTDPMID:22504374
Mmp19Rataflatoxin B1 increases methylationISOMMP19 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of MMP19 geneCTDPMID:27153756

1 to 20 of 93 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp19Ratluteolysis  IEP 1642024 RGD 
Mmp19Ratovarian follicle development  IEP 1642024 RGD 
Mmp19Ratovulation from ovarian follicle  IEP 1642024 RGD 
Mmp19Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Mmp19Ratproteolysis involved_inIEAInterPro:IPR001818 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Mmp19Ratresponse to cAMP  IEP 1642024 RGD 
Mmp19Ratresponse to hormone  IEP 1642024 RGD 

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp19Ratextracellular matrix located_inIEAInterPro:IPR0018181600115GO_REF:0000002InterProGO_REF:0000002

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp19Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Mmp19Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Mmp19Ratmetalloendopeptidase activity enablesISOMMP19 (Homo sapiens)1624291 PMID:10809722RGDPMID:10809722
Mmp19Ratmetalloendopeptidase activity enablesIEAInterPro:IPR001818 and InterPro:IPR0211901600115GO_REF:0000002InterProGO_REF:0000002
Mmp19Ratmetallopeptidase activity enablesIEAUniProtKB-KW:KW-04821600115GO_REF:0000043UniProtGO_REF:0000043
Mmp19Ratmetallopeptidase activity enablesIEAInterPro:IPR006026 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Mmp19Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Mmp19Ratzinc ion binding enablesIEAInterPro:IPR001818 more ...1600115GO_REF:0000002InterProGO_REF:0000002


1 to 10 of 10 rows
#
Reference Title
Reference Citation
1. Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation. Chavey C, etal., J Biol Chem. 2003 Apr 4;278(14):11888-96. Epub 2003 Jan 15.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Regulation of matrix metalloproteinase-19 messenger RNA expression in the rat ovary. Jo M and Curry TE Jr, Biol Reprod. 2004 Dec;71(6):1796-806. Epub 2004 Jul 30.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Diet-induced obesity and reduced skin cancer susceptibility in matrix metalloproteinase 19-deficient mice. Pendas AM, etal., Mol Cell Biol. 2004 Jun;24(12):5304-13.
7. In vivo gene expression revealed by cDNA arrays: the pattern in relapsing-remitting multiple sclerosis patients compared with normal subjects. Ramanathan M, etal., J Neuroimmunol. 2001 Jun 1;116(2):213-9.
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
1 to 10 of 10 rows
PMID:10809722   PMID:24006456  



Mmp19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,805,732 - 1,814,054 (+)NCBIGRCr8
mRatBN7.271,221,229 - 1,229,555 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl71,221,343 - 1,229,555 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,984,499 - 3,992,199 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,860,160 - 5,867,860 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.076,157,051 - 6,164,751 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.073,216,392 - 3,224,202 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl73,216,497 - 3,224,201 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,187,758 - 3,195,773 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.472,091,532 - 2,099,235 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.172,091,513 - 2,098,874 (+)NCBI
Celera71,092,107 - 1,099,811 (+)NCBICelera
Cytogenetic Map7q11NCBI
MMP19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381255,835,433 - 55,842,936 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1255,835,433 - 55,842,966 (-)EnsemblGRCh38hg38GRCh38
GRCh371256,229,217 - 56,236,720 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,515,481 - 54,523,002 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map12q13.2NCBI
HuRef1253,267,597 - 53,276,011 (-)NCBIHuRef
CHM1_11256,195,994 - 56,203,543 (-)NCBICHM1_1
T2T-CHM13v2.01255,802,080 - 55,809,587 (-)NCBIT2T-CHM13v2.0
Mmp19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,626,779 - 128,636,696 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,626,779 - 128,636,693 (+)EnsemblGRCm39 Ensembl
GRCm3810128,790,910 - 128,800,827 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,790,910 - 128,800,824 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710128,227,966 - 128,237,880 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610128,193,922 - 128,202,417 (+)NCBIMGSCv36mm8
Celera10131,183,125 - 131,193,039 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.16NCBI
Mmp19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,473,279 - 3,479,620 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,473,279 - 3,479,620 (-)NCBIChiLan1.0ChiLan1.0
MMP19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,485,164 - 38,492,033 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,481,734 - 38,488,803 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01233,068,282 - 33,075,324 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11233,794,180 - 33,801,658 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,794,249 - 33,801,658 (+)Ensemblpanpan1.1panPan2
MMP19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110219,193 - 224,873 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10219,618 - 224,778 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10281,068 - 286,898 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010225,879 - 231,709 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10225,881 - 231,658 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110203,820 - 209,650 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010446,639 - 452,469 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010570,854 - 576,684 (-)NCBIUU_Cfam_GSD_1.0
Mmp19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,565,755 - 58,571,502 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646299,059 - 304,430 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646298,854 - 304,479 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,280,130 - 21,285,774 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,279,514 - 21,285,943 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2522,759,697 - 22,766,115 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MMP19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11151,786,076 - 51,794,325 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037194,199,991 - 194,207,487 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmp19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480212,175,989 - 12,181,578 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480212,176,406 - 12,182,128 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Mmp19
24 total Variants

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:35
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000008909
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 9 of 9 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat

1 to 9 of 9 rows
AI072476  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.271,229,339 - 1,229,553 (+)MAPPERmRatBN7.2
Rnor_6.073,224,462 - 3,224,675NCBIRnor6.0
Rnor_5.073,196,032 - 3,196,245UniSTSRnor5.0
RGSC_v3.472,099,496 - 2,099,709UniSTSRGSC3.4
Celera71,100,091 - 1,100,304UniSTS
Cytogenetic Map7q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000008909   ⟹   ENSRNOP00000008909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl71,221,343 - 1,229,555 (+)Ensembl
Rnor_6.0 Ensembl73,216,497 - 3,224,201 (+)Ensembl
RefSeq Acc Id: NM_001107159   ⟹   NP_001100629
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,805,875 - 1,813,578 (+)NCBI
mRatBN7.271,221,373 - 1,229,075 (+)NCBI
Rnor_6.073,216,497 - 3,224,200 (+)NCBI
Rnor_5.073,187,758 - 3,195,773 (+)NCBI
RGSC_v3.472,091,532 - 2,099,235 (+)RGD
Celera71,092,107 - 1,099,811 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240758   ⟹   XP_006240820
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,805,732 - 1,814,054 (+)NCBI
mRatBN7.271,221,229 - 1,229,555 (+)NCBI
Rnor_6.073,216,392 - 3,224,202 (+)NCBI
Rnor_5.073,187,758 - 3,195,773 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039078969   ⟹   XP_038934897
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,805,801 - 1,814,054 (+)NCBI
mRatBN7.271,221,297 - 1,229,555 (+)NCBI
Protein RefSeqs NP_001100629 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240820 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934897 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ACN90949 (Get FASTA)   NCBI Sequence Viewer  
  EDL84805 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000008909
  ENSRNOP00000008909.4
RefSeq Acc Id: NP_001100629   ⟸   NM_001107159
- Peptide Label: precursor
- UniProtKB: C0M4B0 (UniProtKB/TrEMBL),   A6KSI7 (UniProtKB/TrEMBL),   F7EUD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240820   ⟸   XM_006240758
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000008909   ⟸   ENSRNOT00000008909
RefSeq Acc Id: XP_038934897   ⟸   XM_039078969
- Peptide Label: isoform X2
Peptidase metallopeptidase

Name Modeler Protein Id AA Range Protein Structure
AF-C0M4B0-F1-model_v2 AlphaFold C0M4B0 1-517 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694951
Promoter ID:EPDNEW_R5476
Type:initiation region
Name:Mmp19_1
Description:matrix metallopeptidase 19
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.073,216,482 - 3,216,542EPDNEW


1 to 37 of 37 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-35332 BioCyc
Ensembl Genes ENSRNOG00000006778 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008909 ENTREZGENE
  ENSRNOT00000008909.8 UniProtKB/TrEMBL
Gene3D-CATH 2.110.10.10 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro Hemopexin-like_dom_sf UniProtKB/TrEMBL
  Hemopexin/matrixin UniProtKB/TrEMBL
  Hemopexin/matrixin_repeat UniProtKB/TrEMBL
  M10A_MMP UniProtKB/TrEMBL
  MetalloPept_cat_dom UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/TrEMBL
  Pept_M10A_matrix_cons-reg UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/TrEMBL
  Peptidoglycan-bd-like UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/TrEMBL
KEGG Report rno:304608 UniProtKB/TrEMBL
NCBI Gene 304608 ENTREZGENE
PANTHER MATRIX METALLOPROTEINASE UniProtKB/TrEMBL
  PTHR10201:SF166 UniProtKB/TrEMBL
Pfam Hemopexin UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/TrEMBL
  PG_binding_1 UniProtKB/TrEMBL
PhenoGen Mmp19 PhenoGen
PIRSF Peptidase_M10A_matrix UniProtKB/TrEMBL
PRINTS MATRIXIN UniProtKB/TrEMBL
PROSITE HEMOPEXIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006778 RatGTEx
SMART SM00120 UniProtKB/TrEMBL
  ZnMc UniProtKB/TrEMBL
Superfamily-SCOP Hemopexin UniProtKB/TrEMBL
  Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  PGBD_like UniProtKB/TrEMBL
UniProt A6KSI7 ENTREZGENE, UniProtKB/TrEMBL
  C0M4B0 ENTREZGENE
  F7EUD4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary C0M4B0 UniProtKB/TrEMBL
1 to 37 of 37 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Mmp19  matrix metallopeptidase 19  Mmp19_predicted  matrix metalloproteinase 19 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Mmp19_predicted  matrix metalloproteinase 19 (predicted)      Symbol and Name status set to approved 70820 APPROVED