Crlf1 (cytokine receptor-like factor 1) - Rat Genome Database

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Gene: Crlf1 (cytokine receptor-like factor 1) Rattus norvegicus
Analyze
Symbol: Crlf1
Name: cytokine receptor-like factor 1
RGD ID: 1311371
Description: Predicted to enable cytokine binding activity and cytokine receptor activity. Predicted to contribute to ciliary neurotrophic factor receptor binding activity and cytokine activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; negative regulation of motor neuron apoptotic process; and ureteric bud development. Predicted to be part of CRLF-CLCF1 complex and receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in cold-induced sweating syndrome 1. Orthologous to human CRLF1 (cytokine receptor like factor 1); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC290655
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,958,695 - 18,970,026 (-)NCBIGRCr8
mRatBN7.21618,924,722 - 18,936,049 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,924,722 - 18,935,997 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,966,510 - 18,977,787 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,099,327 - 20,110,590 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,019,472 - 19,030,749 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,675,042 - 20,686,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,675,042 - 20,686,317 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,530,521 - 20,541,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,431,472 - 19,442,747 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,431,472 - 19,442,745 (-)NCBI
Celera1619,116,098 - 19,127,373 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Crlf1RatMultiple Abnormalities susceptibilityISOCRLF1 (Homo sapiens)1600970Cold-induced sweating syndrome-1 and OMIM:272430RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Crlf1Ratcold-induced sweating syndrome  ISOCRLF1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:17436251 more ...
Crlf1Ratcold-induced sweating syndrome 1  ISOCRLF1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:12509788 more ...
Crlf1Ratcone-rod dystrophy 12  ISOCRLF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Cone-rod dystrophy 12ClinVarPMID:25741868 and PMID:31497877
Crlf1Ratgenetic disease  ISOCRLF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:17436251 more ...
Crlf1RatMegalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1  ISOCRLF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1ClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Crlf1Ratcold-induced sweating syndrome  ISOCRLF1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Crlf1Ratcold-induced sweating syndrome 1  ISOCRLF1 (Homo sapiens)7240710 OMIM 

1 to 20 of 102 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Crlf1Rat1,2-dimethylhydrazine decreases expressionEXP 64804641 and 2-Dimethylhydrazine results in decreased expression of CRLF1 mRNACTDPMID:27840820
Crlf1Rat1,2-dimethylhydrazine increases expressionISOCrlf1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of CRLF1 mRNACTDPMID:22206623
Crlf1Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of CRLF1 mRNACTDPMID:30723492
Crlf1Rat17beta-estradiol multiple interactionsISOCRLF1 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of CRLF1 mRNA and [Progesterone co-treated with Estradiol] results in increased expression of CRLF1 mRNACTDPMID:17404688 and PMID:30165855
Crlf1Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOCrlf1 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Crlf1Rat2,2',5,5'-tetrachlorobiphenyl increases expressionISOCRLF1 (Homo sapiens)64804642 more ...CTDPMID:36804509
Crlf1Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOCrlf1 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Crlf1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOCRLF1 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of CRLF1 mRNACTDPMID:20106945 and PMID:21632981
Crlf1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of CRLF1 mRNACTDPMID:32109520
Crlf1Rat2,3,7,8-Tetrachlorodibenzofuran increases expressionEXP 64804642 more ...CTDPMID:32109520
Crlf1Rat2,4-dinitrobenzenesulfonic acid increases expressionISOCrlf1 (Mus musculus)64804642 and 4-dinitrobenzenesulfonic acid results in increased expression of CRLF1 mRNACTDPMID:30116771
Crlf1Rat3,3',4,4',5-pentachlorobiphenyl decreases expressionISOCRLF1 (Homo sapiens)64804643 more ...CTDPMID:23146750
Crlf1Rat3,3',4,4',5-pentachlorobiphenyl increases expressionEXP 64804643 more ...CTDPMID:32119087
Crlf1Rat4,4'-sulfonyldiphenol increases expressionISOCrlf1 (Mus musculus)6480464bisphenol S results in increased expression of CRLF1 mRNACTDPMID:30951980
Crlf1Rat4-hydroxyphenyl retinamide decreases expressionISOCrlf1 (Mus musculus)6480464Fenretinide results in decreased expression of CRLF1 mRNACTDPMID:28973697
Crlf1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of CRLF1 mRNACTDPMID:24780913
Crlf1Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of CRLF1 mRNACTDPMID:30047161
Crlf1Ratacrylamide affects expressionEXP 6480464Acrylamide affects the expression of CRLF1 mRNACTDPMID:28959563
Crlf1Ratacrylamide decreases expressionISOCRLF1 (Homo sapiens)6480464Acrylamide results in decreased expression of CRLF1 mRNACTDPMID:32763439
Crlf1Rataldehydo-D-glucose multiple interactionsISOCrlf1 (Mus musculus)6480464fucoxanthin inhibits the reaction [Glucose results in increased expression of CRLF1 mRNA]CTDPMID:33448797

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Biological Process
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Crlf1Ratbiological_process  ND 159840704/2007: no relevant rat dataRGD 
Crlf1Ratcell surface receptor signaling pathway via STAT involved_inISOCRLF1 (Homo sapiens)1624291 PMID:10966616RGDPMID:10966616
Crlf1Ratcell surface receptor signaling pathway via STAT involved_inIEAUniProtKB:O75462 and ensembl:ENSP000003761881600115GO_REF:0000107EnsemblGO_REF:0000107
Crlf1Ratcytokine-mediated signaling pathway involved_inIBAMGI:104993 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Crlf1Ratnegative regulation of motor neuron apoptotic process involved_inISOCrlf1 (Mus musculus)1624291 PMID:14523086RGDPMID:14523086
Crlf1Ratnegative regulation of motor neuron apoptotic process involved_inIEAUniProtKB:Q9JM58 and ensembl:ENSMUSP000000080321600115GO_REF:0000107EnsemblGO_REF:0000107
Crlf1Ratnegative regulation of neuron apoptotic process involved_inISOCRLF1 (Homo sapiens)1624291 PMID:10966616RGDPMID:10966616
Crlf1Ratnegative regulation of neuron apoptotic process involved_inIEAUniProtKB:O75462 and ensembl:ENSP000003761881600115GO_REF:0000107EnsemblGO_REF:0000107
Crlf1Ratnegative regulation of neuron apoptotic process involved_inIBAMGI:1340030 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Crlf1Ratpositive regulation of cell population proliferation involved_inISOCRLF1 (Homo sapiens)1624291 PMID:10966616RGDPMID:10966616
Crlf1Ratpositive regulation of cell population proliferation involved_inIEAUniProtKB:O75462 and ensembl:ENSP000003761881600115GO_REF:0000107EnsemblGO_REF:0000107
Crlf1Ratpositive regulation of cell population proliferation involved_inIBAMGI:107426 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Crlf1Ratureteric bud development involved_inISOCrlf1 (Mus musculus)1624291 PMID:16545622RGDPMID:16545622
Crlf1Ratureteric bud development involved_inIEAUniProtKB:Q9JM58 and ensembl:ENSMUSP000000080321600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 14 of 14 rows

Cellular Component

  
Object Symbol
Species
Term
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Evidence
With
Reference
Notes
Source
Original Reference(s)
Crlf1RatCRLF-CLCF1 complex part_ofISOCRLF1 (Homo sapiens)1624291 PMID:10966616RGDPMID:10966616
Crlf1RatCRLF-CLCF1 complex part_ofIEAUniProtKB:O75462 and ensembl:ENSP000003761881600115GO_REF:0000107EnsemblGO_REF:0000107
Crlf1RatCRLF-CLCF1 complex part_ofIBAPANTHER:PTN004596323 and UniProtKB:O754621600115GO_REF:0000033GO_CentralGO_REF:0000033
Crlf1Ratexternal side of plasma membrane is_active_inIBAMGI:104579 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Crlf1Ratreceptor complex part_ofIBAMGI:104579 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 9 of 9 rows

  
Object Symbol
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Term
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Evidence
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Reference
Notes
Source
Original Reference(s)
Crlf1Ratciliary neurotrophic factor receptor binding contributes_toISOCRLF1 (Homo sapiens)1624291 PMID:10966616RGDPMID:10966616
Crlf1Ratciliary neurotrophic factor receptor binding contributes_toIEAUniProtKB:O75462 and ensembl:ENSP000003761881600115GO_REF:0000107EnsemblGO_REF:0000107
Crlf1Ratcytokine activity contributes_toISOCRLF1 (Homo sapiens)1624291 PMID:10966616RGDPMID:10966616
Crlf1Ratcytokine activity contributes_toIEAUniProtKB:O75462 and ensembl:ENSP000003761881600115GO_REF:0000107EnsemblGO_REF:0000107
Crlf1Ratcytokine binding enablesISOCRLF1 (Homo sapiens)1624291UniProtKB:Q9UBD9 and PMID:15034937RGDPMID:15034937
Crlf1Ratcytokine binding enablesIBAMGI:105304 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Crlf1Ratcytokine binding enablesIEAUniProtKB:O75462 and ensembl:ENSP000003761881600115GO_REF:0000107EnsemblGO_REF:0000107
Crlf1Ratcytokine receptor activity enablesIBAMGI:104993 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Crlf1Ratprotein binding enablesISOCRLF1 (Homo sapiens)1624291UniProtKB:Q8NEV9 more ...RGDPMID:10966616 more ...
1 to 9 of 9 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Cold-induced sweating syndrome is caused by mutations in the CRLF1 gene. Knappskog PM, etal., Am J Hum Genet. 2003 Feb;72(2):375-83. Epub 2002 Dec 31.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:10966616   PMID:14523086   PMID:15034937   PMID:16545622   PMID:24006456  



Crlf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,958,695 - 18,970,026 (-)NCBIGRCr8
mRatBN7.21618,924,722 - 18,936,049 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,924,722 - 18,935,997 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,966,510 - 18,977,787 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,099,327 - 20,110,590 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,019,472 - 19,030,749 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,675,042 - 20,686,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,675,042 - 20,686,317 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,530,521 - 20,541,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,431,472 - 19,442,747 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,431,472 - 19,442,745 (-)NCBI
Celera1619,116,098 - 19,127,373 (-)NCBICelera
Cytogenetic Map16p14NCBI
CRLF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,593,237 - 18,606,799 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,572,220 - 18,607,741 (-)EnsemblGRCh38hg38GRCh38
GRCh371918,704,047 - 18,717,609 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,565,047 - 18,578,660 (-)NCBINCBI36Build 36hg18NCBI36
Build 341918,565,046 - 18,578,660NCBI
Celera1918,606,237 - 18,619,858 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,266,624 - 18,309,213 (-)NCBIHuRef
CHM1_11918,704,266 - 18,717,662 (-)NCBICHM1_1
T2T-CHM13v2.01918,728,303 - 18,741,874 (-)NCBIT2T-CHM13v2.0
Crlf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,945,798 - 70,956,728 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,945,808 - 70,956,731 (+)EnsemblGRCm39 Ensembl
GRCm38870,493,097 - 70,504,078 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,493,158 - 70,504,081 (+)EnsemblGRCm38mm10GRCm38
MGSCv37873,017,055 - 73,027,980 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,422,145 - 73,433,070 (+)NCBIMGSCv36mm8
Celera873,049,567 - 73,060,492 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Crlf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,998,260 - 3,003,283 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,998,258 - 3,003,553 (+)NCBIChiLan1.0ChiLan1.0
CRLF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,452,262 - 23,465,525 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,460,674 - 22,473,911 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,070,465 - 18,083,701 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,040,355 - 19,048,927 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,040,682 - 19,046,584 (-)Ensemblpanpan1.1panPan2
CRLF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,466,812 - 44,476,055 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,466,810 - 44,472,637 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,376,895 - 44,389,992 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,948,405 - 44,961,499 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,948,246 - 44,958,835 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,185,771 - 44,198,860 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,595,729 - 44,608,819 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,871,168 - 44,884,262 (+)NCBIUU_Cfam_GSD_1.0
Crlf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,147,220 - 203,153,304 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,693,881 - 2,702,131 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,693,881 - 2,702,443 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRLF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,222,367 - 59,233,720 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,222,551 - 59,233,723 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,069,084 - 59,075,048 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRLF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,061,289 - 17,074,930 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,061,621 - 17,074,794 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660742,261,781 - 2,275,479 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crlf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,752,779 - 1,762,244 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,752,773 - 1,762,272 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Crlf1
39 total Variants

Predicted Target Of
Summary Value
Count of predictions:39
Count of miRNA genes:35
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000060097
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 28 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat

1 to 10 of 28 rows
RH128982  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,924,775 - 18,924,931 (+)MAPPERmRatBN7.2
Rnor_6.01620,675,096 - 20,675,251NCBIRnor6.0
Rnor_5.01620,530,575 - 20,530,730UniSTSRnor5.0
RGSC_v3.41619,431,526 - 19,431,681UniSTSRGSC3.4
Celera1619,116,152 - 19,116,307UniSTS
RH 3.4 Map16214.42UniSTS
Cytogenetic Map16p14UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 47 113 63 62 31 24 31 6 187 94 93 45 60 31



Ensembl Acc Id: ENSRNOT00000060097   ⟹   ENSRNOP00000056846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,924,722 - 18,935,997 (-)Ensembl
Rnor_6.0 Ensembl1620,675,042 - 20,686,317 (-)Ensembl
RefSeq Acc Id: NM_001106074   ⟹   NP_001099544
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,695 - 18,969,970 (-)NCBI
mRatBN7.21618,924,722 - 18,935,997 (-)NCBI
Rnor_6.01620,675,042 - 20,686,317 (-)NCBI
Rnor_5.01620,530,521 - 20,541,831 (-)NCBI
RGSC_v3.41619,431,472 - 19,442,747 (-)RGD
Celera1619,116,098 - 19,127,373 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252872   ⟹   XP_006252934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,024 (-)NCBI
mRatBN7.21618,924,733 - 18,936,047 (-)NCBI
Rnor_6.01620,675,052 - 20,686,365 (-)NCBI
Rnor_5.01620,530,521 - 20,541,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252874   ⟹   XP_006252936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,024 (-)NCBI
mRatBN7.21618,924,733 - 18,936,048 (-)NCBI
Rnor_6.01620,675,052 - 20,686,365 (-)NCBI
Rnor_5.01620,530,521 - 20,541,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094330   ⟹   XP_038950258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,026 (-)NCBI
mRatBN7.21618,924,733 - 18,936,049 (-)NCBI
RefSeq Acc Id: XM_039094331   ⟹   XP_038950259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,025 (-)NCBI
mRatBN7.21618,924,733 - 18,936,048 (-)NCBI
RefSeq Acc Id: XM_039094332   ⟹   XP_038950260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,960,134 - 18,970,026 (-)NCBI
mRatBN7.21618,926,161 - 18,936,049 (-)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001099544 (Get FASTA)   NCBI Sequence Viewer  
  XP_006252934 (Get FASTA)   NCBI Sequence Viewer  
  XP_006252936 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950258 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950259 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950260 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL90689 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000056846
  ENSRNOP00000056846.3
  ENSRNOP00000108067
1 to 10 of 10 rows
RefSeq Acc Id: NP_001099544   ⟸   NM_001106074
- Peptide Label: precursor
- UniProtKB: A6KA48 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252934   ⟸   XM_006252872
- Peptide Label: isoform X3
- UniProtKB: D3ZIV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252936   ⟸   XM_006252874
- Peptide Label: isoform X4
- Sequence:
Ensembl Acc Id: ENSRNOP00000056846   ⟸   ENSRNOT00000060097
RefSeq Acc Id: XP_038950258   ⟸   XM_039094330
- Peptide Label: isoform X1
Fibronectin type-III

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIV9-F1-model_v2 AlphaFold D3ZIV9 1-425 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700031
Promoter ID:EPDNEW_R10553
Type:multiple initiation site
Name:Crlf1_1
Description:cytokine receptor-like factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,686,325 - 20,686,385EPDNEW


1 to 26 of 26 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-11782 BioCyc
Ensembl Genes ENSRNOG00000020030 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060097 ENTREZGENE
  ENSRNOT00000060097.3 UniProtKB/TrEMBL
  ENSRNOT00000152774 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Fibronectin_type3 UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Growth/epo_recpt_lig-bind UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Type-I_Cytokine_Rcpt UniProtKB/TrEMBL
KEGG Report rno:290655 UniProtKB/TrEMBL
NCBI Gene 290655 ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  CYTOKINE RECEPTOR-LIKE FACTOR 1 UniProtKB/TrEMBL
Pfam EpoR_lig-bind UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
PhenoGen Crlf1 PhenoGen
PROSITE FN3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020030 RatGTEx
SMART FN3 UniProtKB/TrEMBL
Superfamily-SCOP FN_III-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A6KA48 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIV9 ENTREZGENE, UniProtKB/TrEMBL
1 to 26 of 26 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Crlf1  cytokine receptor-like factor 1   Crlf1_predicted  cytokine receptor-like factor 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Crlf1_predicted  cytokine receptor-like factor 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED