Mcm10 (minichromosome maintenance 10 replication initiation factor) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Mcm10 (minichromosome maintenance 10 replication initiation factor) Rattus norvegicus
Analyze
Symbol: Mcm10
Name: minichromosome maintenance 10 replication initiation factor
RGD ID: 1311330
Description: Predicted to enable DNA binding activity; enzyme binding activity; and identical protein binding activity. Predicted to be involved in DNA damage response and DNA replication initiation. Predicted to act upstream of or within cell population proliferation. Predicted to be located in nucleus. Predicted to be active in nuclear replication fork. Human ortholog(s) of this gene implicated in immunodeficiency 80. Orthologous to human MCM10 (minichromosome maintenance 10 replication initiation factor); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC307126; minichromosome maintenance complex component 10; minichromosome maintenance deficient 10; minichromosome maintenance deficient 10 (S. cerevisiae); protein MCM10 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,172,049 - 78,197,644 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1778,175,398 - 78,197,636 (+)EnsemblGRCr8
mRatBN7.21773,263,788 - 73,288,346 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,266,095 - 73,287,364 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1776,769,674 - 76,793,022 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01780,594,516 - 80,617,865 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01774,645,092 - 74,668,328 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01777,224,218 - 77,245,486 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,224,112 - 77,246,478 (+)Ensemblrn6Rnor6.0
Rnor_5.01778,890,310 - 78,911,578 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41784,354,481 - 84,375,749 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1772,705,757 - 72,728,402 (+)NCBICelera
RGSC_v3.11784,365,143 - 84,386,073 (+)NCBI
Cytogenetic Map17q12.3NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-colchicine  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2'-Methylenebis(4-methyl-6-tert-butylphenol)  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-methoxyethanol  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
adenine  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
arsenite(3-)  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
bazedoxifene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
buta-1,3-diene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diethyl maleate  (EXP)
dioxygen  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furan  (EXP)
genistein  (ISO)
glycidol  (EXP)
GSK-J4  (ISO)
GW 7647  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
Lasiocarpine  (ISO)
lidocaine  (EXP)
lucanthone  (ISO)
metformin  (EXP)
methamphetamine  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
mitomycin C  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (ISO)
phytoestrogen  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nuclear replication fork  (IBA)
nucleolus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11095689   PMID:17823614   PMID:21693137   PMID:24115439   PMID:24726359  


Genomics

Comparative Map Data
Mcm10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,172,049 - 78,197,644 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1778,175,398 - 78,197,636 (+)EnsemblGRCr8
mRatBN7.21773,263,788 - 73,288,346 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,266,095 - 73,287,364 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1776,769,674 - 76,793,022 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01780,594,516 - 80,617,865 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01774,645,092 - 74,668,328 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01777,224,218 - 77,245,486 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,224,112 - 77,246,478 (+)Ensemblrn6Rnor6.0
Rnor_5.01778,890,310 - 78,911,578 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41784,354,481 - 84,375,749 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1772,705,757 - 72,728,402 (+)NCBICelera
RGSC_v3.11784,365,143 - 84,386,073 (+)NCBI
Cytogenetic Map17q12.3NCBI
MCM10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381013,161,558 - 13,211,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1013,161,554 - 13,211,110 (+)Ensemblhg38GRCh38
GRCh371013,203,558 - 13,253,110 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361013,243,587 - 13,293,110 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341013,243,586 - 13,293,108NCBI
Celera1013,130,372 - 13,179,899 (+)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1013,116,201 - 13,165,701 (+)NCBIHuRef
CHM1_11013,203,749 - 13,253,219 (+)NCBICHM1_1
T2T-CHM13v2.01013,176,180 - 13,225,648 (+)NCBIT2T-CHM13v2.0
Mcm10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3924,995,535 - 5,017,602 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl24,994,525 - 5,017,602 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3824,990,724 - 5,012,791 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl24,989,714 - 5,012,791 (-)Ensemblmm10GRCm38
MGSCv3724,911,770 - 4,933,837 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3624,908,020 - 4,930,007 (-)NCBIMGSCv36mm8
Celera24,946,062 - 4,967,571 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map23.12NCBI
Mcm10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554621,153,058 - 1,188,799 (+)Ensembl
ChiLan1.0NW_0049554621,151,163 - 1,186,601 (+)NCBIChiLan1.0ChiLan1.0
MCM10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2825,686,152 - 25,735,481 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11025,691,576 - 25,740,040 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01013,165,811 - 13,215,024 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11013,138,824 - 13,187,992 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1013,138,824 - 13,187,991 (+)EnsemblpanPan2panpan1.1
MCM10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1223,288,249 - 23,344,060 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl223,292,253 - 23,344,719 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha220,246,666 - 20,355,349 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0223,674,961 - 23,712,688 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1220,784,656 - 20,841,490 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0221,627,386 - 21,684,217 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0222,294,562 - 22,400,674 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101955652
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093442,821,945 - 2,867,389 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936862423,220 - 468,574 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCM10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1048,480,705 - 48,538,952 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11048,481,292 - 48,523,921 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MCM10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1913,200,018 - 13,252,830 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl913,204,246 - 13,253,367 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605118,729,838 - 18,781,807 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mcm10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248055,728,569 - 5,765,862 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248055,728,781 - 5,766,796 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mcm10
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11411,339,765 - 11,362,719 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mcm10
158 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:452
Count of miRNA genes:246
Interacting mature miRNAs:297
Transcripts:ENSRNOT00000024178
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)177061350286062352Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176855004093515804Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176369714782818564Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)176456982086954580Rat

Markers in Region
RH132027  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,287,490 - 73,287,690 (+)MAPPERmRatBN7.2
Rnor_6.01777,245,613 - 77,245,812NCBIRnor6.0
Rnor_5.01778,911,705 - 78,911,904UniSTSRnor5.0
RGSC_v3.41784,375,876 - 84,376,075UniSTSRGSC3.4
Celera1772,728,529 - 72,728,728UniSTS
RH 3.4 Map17727.7UniSTS
Cytogenetic Map17q12.3UniSTS
RH132593  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,287,074 - 73,287,275 (+)MAPPERmRatBN7.2
Rnor_6.01777,245,197 - 77,245,397NCBIRnor6.0
Rnor_5.01778,911,289 - 78,911,489UniSTSRnor5.0
RGSC_v3.41784,375,460 - 84,375,660UniSTSRGSC3.4
Celera1772,728,113 - 72,728,313UniSTS
RH 3.4 Map17725.7UniSTS
Cytogenetic Map17q12.3UniSTS
BF397898  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,286,486 - 73,286,662 (+)MAPPERmRatBN7.2
Rnor_6.01777,244,609 - 77,244,784NCBIRnor6.0
Rnor_5.01778,910,701 - 78,910,876UniSTSRnor5.0
RGSC_v3.41784,374,872 - 84,375,047UniSTSRGSC3.4
Celera1772,727,525 - 72,727,700UniSTS
RH 3.4 Map17728.9UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 65 163 91 90 59 91 59 6 352 189 11 142 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000024178   ⟹   ENSRNOP00000024178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1778,175,398 - 78,197,636 (+)Ensembl
mRatBN7.2 Ensembl1773,266,095 - 73,287,364 (+)Ensembl
Rnor_6.0 Ensembl1777,224,112 - 77,246,478 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000148655   ⟹   ENSRNOP00000103505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1778,175,398 - 78,197,636 (+)Ensembl
RefSeq Acc Id: NM_001107366   ⟹   NP_001100836
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,175,387 - 78,196,655 (+)NCBI
mRatBN7.21773,266,095 - 73,287,364 (+)NCBI
Rnor_6.01777,224,218 - 77,245,486 (+)NCBI
Rnor_5.01778,890,310 - 78,911,578 (+)NCBI
RGSC_v3.41784,354,481 - 84,375,749 (+)RGD
Celera1772,705,757 - 72,728,402 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095781   ⟹   XP_038951709
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,172,049 - 78,197,644 (+)NCBI
mRatBN7.21773,263,788 - 73,288,346 (+)NCBI
RefSeq Acc Id: XM_039095782   ⟹   XP_038951710
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,182,696 - 78,197,644 (+)NCBI
mRatBN7.21773,273,407 - 73,288,346 (+)NCBI
RefSeq Acc Id: XM_063276495   ⟹   XP_063132565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,179,159 - 78,197,644 (+)NCBI
RefSeq Acc Id: NP_001100836   ⟸   NM_001107366
- UniProtKB: D3Z8C4 (UniProtKB/TrEMBL),   A6JLZ2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024178   ⟸   ENSRNOT00000024178
RefSeq Acc Id: XP_038951709   ⟸   XM_039095781
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951710   ⟸   XM_039095782
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063132565   ⟸   XM_063276495
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000103505   ⟸   ENSRNOT00000148655
Protein Domains
Replication factor Mcm10 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z8C4-F1-model_v2 AlphaFold D3Z8C4 1-889 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700572
Promoter ID:EPDNEW_R11096
Type:initiation region
Name:Mcm10_1
Description:minichromosome maintenance 10 replication initiation factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01777,224,203 - 77,224,263EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311330 AgrOrtholog
BioCyc Gene G2FUF-8689 BioCyc
Ensembl Genes ENSRNOG00000017981 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024178 ENTREZGENE
  ENSRNOT00000024178.8 UniProtKB/TrEMBL
  ENSRNOT00000148655 ENTREZGENE
  ENSRNOT00000148655.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
  Immunoglobulin FC, subunit C UniProtKB/TrEMBL
InterPro Mcm10 UniProtKB/TrEMBL
  Mcm10 UniProtKB/TrEMBL
  MCM10_OB UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Znf_Mcm10/DnaG UniProtKB/TrEMBL
  Znf_Mcm10_C UniProtKB/TrEMBL
KEGG Report rno:307126 UniProtKB/TrEMBL
NCBI Gene 307126 ENTREZGENE
PANTHER PROTEIN MCM10 HOMOLOG UniProtKB/TrEMBL
  PTHR13454 UniProtKB/TrEMBL
Pfam Mcm10 UniProtKB/TrEMBL
  MCM10_OB UniProtKB/TrEMBL
  zf-CCCH_Mcm10 UniProtKB/TrEMBL
  zf-primase UniProtKB/TrEMBL
PhenoGen Mcm10 PhenoGen
RatGTEx ENSRNOG00000017981 RatGTEx
SMART Mcm10 UniProtKB/TrEMBL
UniProt A0ABK0LSI9_RAT UniProtKB/TrEMBL
  A6JLZ2 ENTREZGENE, UniProtKB/TrEMBL
  D3Z8C4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-09-16 Mcm10  minichromosome maintenance 10 replication initiation factor  Mcm10  minichromosome maintenance complex component 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-24 Mcm10  minichromosome maintenance complex component 10  Mcm10  minichromosome maintenance deficient 10 (S. cerevisiae)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Mcm10  minichromosome maintenance deficient 10 (S. cerevisiae)   Mcm10_predicted  minichromosome maintenance deficient 10 (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mcm10_predicted  minichromosome maintenance deficient 10 (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED