Mcm10 (minichromosome maintenance 10 replication initiation factor) - Rat Genome Database

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Gene: Mcm10 (minichromosome maintenance 10 replication initiation factor) Rattus norvegicus
Analyze
Symbol: Mcm10
Name: minichromosome maintenance 10 replication initiation factor
RGD ID: 1311330
Description: Predicted to enable DNA binding activity; enzyme binding activity; and identical protein binding activity. Predicted to be involved in DNA damage response and DNA replication initiation. Predicted to act upstream of or within cell population proliferation. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nuclear replication fork. Human ortholog(s) of this gene implicated in immunodeficiency 80. Orthologous to human MCM10 (minichromosome maintenance 10 replication initiation factor); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC307126; minichromosome maintenance complex component 10; minichromosome maintenance deficient 10; minichromosome maintenance deficient 10 (S. cerevisiae); protein MCM10 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,172,049 - 78,197,644 (+)NCBIGRCr8
mRatBN7.21773,263,788 - 73,288,346 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,266,095 - 73,287,364 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1776,769,674 - 76,793,022 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01780,594,516 - 80,617,865 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01774,645,092 - 74,668,328 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01777,224,218 - 77,245,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,224,112 - 77,246,478 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01778,890,310 - 78,911,578 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41784,354,481 - 84,375,749 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11784,365,143 - 84,386,073 (+)NCBI
Celera1772,705,757 - 72,728,402 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcm10RatCOVID-19  ISOMCM10 (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcm10Rathypoparathyroidism-deafness-renal disease syndrome  ISOMCM10 (Homo sapiens)8554872ClinVar Annotator: match by term: Hypoparathyroidism more ...ClinVarPMID:25741868
Mcm10Ratimmunodeficiency 80  ISOMCM10 (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency 80 with or without congenital cardiomyopathyClinVarPMID:25741868 more ...
Mcm10Ratprimary open angle glaucoma  ISOMCM10 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary open angle glaucomaClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcm10Rathepatocellular carcinoma  ISOMCM10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28284560
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcm10Ratimmunodeficiency 80  ISOMCM10 (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcm10Rat(1->4)-beta-D-glucan multiple interactionsISOMcm10 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of MCM10 mRNACTDPMID:36331819
Mcm10Rat(S)-colchicine decreases expressionISOMCM10 (Homo sapiens)6480464Colchicine results in decreased expression of MCM10 mRNACTDPMID:24211769
Mcm10Rat1,2-dichloroethane decreases expressionISOMcm10 (Mus musculus)6480464ethylene dichloride results in decreased expression of MCM10 mRNACTDPMID:28189721 and PMID:28960355
Mcm10Rat1,2-dimethylhydrazine multiple interactionsISOMcm10 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MCM10 mRNACTDPMID:22206623
Mcm10Rat17beta-estradiol increases expressionISOMCM10 (Homo sapiens)6480464Estradiol results in increased expression of MCM10 mRNACTDPMID:16474171 more ...
Mcm10Rat17beta-estradiol decreases expressionISOMcm10 (Mus musculus)6480464Estradiol results in decreased expression of MCM10 mRNACTDPMID:39298647
Mcm10Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of MCM10 mRNACTDPMID:32145629
Mcm10Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOMcm10 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Mcm10Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOMcm10 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Mcm10Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOMCM10 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of MCM10 mRNACTDPMID:21802500
Mcm10Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of MCM10 mRNACTDPMID:33387578
Mcm10Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of MCM10 mRNACTDPMID:32109520
Mcm10Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOMcm10 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of MCM10 mRNACTDPMID:21570461
Mcm10Rat2-methoxyethanol increases expressionEXP 6480464methyl cellosolve results in increased expression of MCM10 mRNACTDPMID:21061450
Mcm10Rat3-methylcholanthrene increases expressionISOMcm10 (Mus musculus)6480464Methylcholanthrene results in increased expression of MCM10 mRNACTDPMID:20713471
Mcm10Rat4,4'-sulfonyldiphenol increases expressionISOMcm10 (Mus musculus)6480464bisphenol S results in increased expression of MCM10 mRNACTDPMID:39298647
Mcm10Rat5-fluorouracil affects expressionISOMCM10 (Homo sapiens)6480464Fluorouracil affects the expression of MCM10 mRNACTDPMID:16584549
Mcm10Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of MCM10 mRNACTDPMID:24780913 and PMID:30047161
Mcm10Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of MCM10 mRNACTDPMID:31881176
Mcm10Ratacrylamide increases expressionISOMcm10 (Mus musculus)6480464Acrylamide results in increased expression of MCM10 mRNACTDPMID:30807115 and PMID:35032568

1 to 20 of 157 rows

Biological Process
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcm10Ratcell population proliferation acts_upstream_of_or_withinISOMcm10 (Mus musculus)1624291MGI:5296322 PMID:21693137RGDPMID:21693137
Mcm10Ratcell population proliferation acts_upstream_of_or_withinIEAUniProtKB:Q0VBD2 and ensembl:ENSMUSP000001000501600115GO_REF:0000107EnsemblGO_REF:0000107
Mcm10RatDNA damage response involved_inISOMCM10 (Homo sapiens)1624291 PMID:24726359RGDPMID:24726359
Mcm10RatDNA damage response involved_inIEAUniProtKB:Q7L590 and ensembl:ENSP000003679861600115GO_REF:0000107EnsemblGO_REF:0000107
Mcm10RatDNA replication involved_inIEAInterPro:IPR0154081600115GO_REF:0000002InterProGO_REF:0000002
Mcm10RatDNA replication involved_inIEAUniProtKB-KW:KW-02351600115GO_REF:0000043UniProtGO_REF:0000043
Mcm10RatDNA replication initiation involved_inISOMCM10 (Homo sapiens)1624291 PMID:32865517RGDPMID:32865517
Mcm10RatDNA replication initiation involved_inIEAUniProtKB:Q7L590 and ensembl:ENSP000003679861600115GO_REF:0000107EnsemblGO_REF:0000107
Mcm10RatDNA replication initiation involved_inIEAInterPro:IPR0401841600115GO_REF:0000002InterProGO_REF:0000002
Mcm10RatDNA replication initiation involved_inIBAPANTHER:PTN000335708 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 10 of 10 rows

Cellular Component
1 to 10 of 10 rows

  
Object Symbol
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Reference
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Original Reference(s)
Mcm10Ratnuclear replication fork is_active_inIBAPANTHER:PTN000335708 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mcm10Ratnucleolus located_inISOMCM10 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Mcm10Ratnucleolus located_inIEAUniProtKB:Q7L590 and ensembl:ENSP000003679861600115GO_REF:0000107EnsemblGO_REF:0000107
Mcm10Ratnucleoplasm located_inIEAUniProtKB:Q7L590 and ensembl:ENSP000003679861600115GO_REF:0000107EnsemblGO_REF:0000107
Mcm10Ratnucleoplasm located_inISOMCM10 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Mcm10Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Mcm10Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Mcm10Ratnucleus located_inIEAUniProtKB:Q7L590 and ensembl:ENSP000003679861600115GO_REF:0000107EnsemblGO_REF:0000107
Mcm10Ratnucleus located_inIEAInterPro:IPR0154081600115GO_REF:0000002InterProGO_REF:0000002
Mcm10Ratnucleus located_inISOMCM10 (Homo sapiens)1624291 PMID:11095689 and PMID:32865517RGDPMID:11095689 and PMID:32865517
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Molecular Function
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1 to 12 of 12 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11095689   PMID:17823614   PMID:21693137   PMID:24115439   PMID:24726359  



Mcm10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,172,049 - 78,197,644 (+)NCBIGRCr8
mRatBN7.21773,263,788 - 73,288,346 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,266,095 - 73,287,364 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1776,769,674 - 76,793,022 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01780,594,516 - 80,617,865 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01774,645,092 - 74,668,328 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01777,224,218 - 77,245,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,224,112 - 77,246,478 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01778,890,310 - 78,911,578 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41784,354,481 - 84,375,749 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11784,365,143 - 84,386,073 (+)NCBI
Celera1772,705,757 - 72,728,402 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
MCM10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381013,161,558 - 13,211,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1013,161,558 - 13,211,110 (+)EnsemblGRCh38hg38GRCh38
GRCh371013,203,558 - 13,253,110 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361013,243,587 - 13,293,110 (+)NCBINCBI36Build 36hg18NCBI36
Build 341013,243,586 - 13,293,108NCBI
Celera1013,130,372 - 13,179,899 (+)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1013,116,201 - 13,165,701 (+)NCBIHuRef
CHM1_11013,203,749 - 13,253,219 (+)NCBICHM1_1
T2T-CHM13v2.01013,176,180 - 13,225,648 (+)NCBIT2T-CHM13v2.0
Mcm10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3924,995,535 - 5,017,602 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl24,994,525 - 5,017,602 (-)EnsemblGRCm39 Ensembl
GRCm3824,990,724 - 5,012,791 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl24,989,714 - 5,012,791 (-)EnsemblGRCm38mm10GRCm38
MGSCv3724,911,770 - 4,933,837 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3624,908,020 - 4,930,007 (-)NCBIMGSCv36mm8
Celera24,946,062 - 4,967,571 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map23.12NCBI
Mcm10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554621,153,058 - 1,188,799 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554621,151,163 - 1,186,601 (+)NCBIChiLan1.0ChiLan1.0
MCM10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2825,686,152 - 25,735,481 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11025,691,576 - 25,740,040 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01013,165,811 - 13,215,024 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11013,138,824 - 13,187,992 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1013,138,824 - 13,187,991 (+)Ensemblpanpan1.1panPan2
MCM10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1223,288,249 - 23,344,060 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl223,292,253 - 23,344,719 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha220,246,666 - 20,355,349 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0223,674,961 - 23,712,688 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1220,784,656 - 20,841,490 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0221,627,386 - 21,684,217 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0222,294,562 - 22,400,674 (-)NCBIUU_Cfam_GSD_1.0
LOC101955652
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093442,821,945 - 2,867,389 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936862423,220 - 468,574 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCM10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1048,480,705 - 48,538,952 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11048,481,292 - 48,523,921 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MCM10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1913,200,018 - 13,252,830 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl913,204,246 - 13,253,367 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605118,729,838 - 18,781,807 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mcm10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248055,728,569 - 5,765,862 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248055,728,781 - 5,766,796 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Mcm10
149 total Variants

Predicted Target Of
Summary Value
Count of predictions:452
Count of miRNA genes:246
Interacting mature miRNAs:297
Transcripts:ENSRNOT00000024178
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 22 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)177061350286062352Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat

1 to 10 of 22 rows
RH132027  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,287,490 - 73,287,690 (+)MAPPERmRatBN7.2
Rnor_6.01777,245,613 - 77,245,812NCBIRnor6.0
Rnor_5.01778,911,705 - 78,911,904UniSTSRnor5.0
RGSC_v3.41784,375,876 - 84,376,075UniSTSRGSC3.4
Celera1772,728,529 - 72,728,728UniSTS
RH 3.4 Map17727.7UniSTS
Cytogenetic Map17q12.3UniSTS
RH132593  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,287,074 - 73,287,275 (+)MAPPERmRatBN7.2
Rnor_6.01777,245,197 - 77,245,397NCBIRnor6.0
Rnor_5.01778,911,289 - 78,911,489UniSTSRnor5.0
RGSC_v3.41784,375,460 - 84,375,660UniSTSRGSC3.4
Celera1772,728,113 - 72,728,313UniSTS
RH 3.4 Map17725.7UniSTS
Cytogenetic Map17q12.3UniSTS
BF397898  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,286,486 - 73,286,662 (+)MAPPERmRatBN7.2
Rnor_6.01777,244,609 - 77,244,784NCBIRnor6.0
Rnor_5.01778,910,701 - 78,910,876UniSTSRnor5.0
RGSC_v3.41784,374,872 - 84,375,047UniSTSRGSC3.4
Celera1772,727,525 - 72,727,700UniSTS
RH 3.4 Map17728.9UniSTS
Cytogenetic Map17q12.3UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000024178   ⟹   ENSRNOP00000024178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1773,266,095 - 73,287,364 (+)Ensembl
Rnor_6.0 Ensembl1777,224,112 - 77,246,478 (+)Ensembl
RefSeq Acc Id: NM_001107366   ⟹   NP_001100836
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,175,387 - 78,196,655 (+)NCBI
mRatBN7.21773,266,095 - 73,287,364 (+)NCBI
Rnor_6.01777,224,218 - 77,245,486 (+)NCBI
Rnor_5.01778,890,310 - 78,911,578 (+)NCBI
RGSC_v3.41784,354,481 - 84,375,749 (+)RGD
Celera1772,705,757 - 72,728,402 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095781   ⟹   XP_038951709
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,172,049 - 78,197,644 (+)NCBI
mRatBN7.21773,263,788 - 73,288,346 (+)NCBI
RefSeq Acc Id: XM_039095782   ⟹   XP_038951710
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,182,696 - 78,197,644 (+)NCBI
mRatBN7.21773,273,407 - 73,288,346 (+)NCBI
RefSeq Acc Id: XM_063276495   ⟹   XP_063132565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,179,159 - 78,197,644 (+)NCBI
Protein RefSeqs NP_001100836 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951709 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951710 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132565 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL78669 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024178
  ENSRNOP00000024178.5
  ENSRNOP00000103505
RefSeq Acc Id: NP_001100836   ⟸   NM_001107366
- UniProtKB: D3Z8C4 (UniProtKB/TrEMBL),   A6JLZ2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024178   ⟸   ENSRNOT00000024178
RefSeq Acc Id: XP_038951709   ⟸   XM_039095781
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951710   ⟸   XM_039095782
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063132565   ⟸   XM_063276495
- Peptide Label: isoform X2
Replication factor Mcm10 C-terminal

Name Modeler Protein Id AA Range Protein Structure
AF-D3Z8C4-F1-model_v2 AlphaFold D3Z8C4 1-889 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700572
Promoter ID:EPDNEW_R11096
Type:initiation region
Name:Mcm10_1
Description:minichromosome maintenance 10 replication initiation factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01777,224,203 - 77,224,263EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-8689 BioCyc
Ensembl Genes ENSRNOG00000017981 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024178 ENTREZGENE
  ENSRNOT00000024178.7 UniProtKB/TrEMBL
  ENSRNOT00000148655 ENTREZGENE
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
  Immunoglobulin FC, subunit C UniProtKB/TrEMBL
InterPro Mcm10 UniProtKB/TrEMBL
  Mcm10 UniProtKB/TrEMBL
  MCM10_OB UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Znf_Mcm10/DnaG UniProtKB/TrEMBL
KEGG Report rno:307126 UniProtKB/TrEMBL
NCBI Gene 307126 ENTREZGENE
PANTHER PROTEIN MCM10 HOMOLOG UniProtKB/TrEMBL
  PTHR13454 UniProtKB/TrEMBL
Pfam Mcm10 UniProtKB/TrEMBL
  MCM10_OB UniProtKB/TrEMBL
  zf-primase UniProtKB/TrEMBL
PhenoGen Mcm10 PhenoGen
RatGTEx ENSRNOG00000017981 RatGTEx
SMART Mcm10 UniProtKB/TrEMBL
UniProt A6JLZ2 ENTREZGENE, UniProtKB/TrEMBL
  D3Z8C4 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-09-16 Mcm10  minichromosome maintenance 10 replication initiation factor  Mcm10  minichromosome maintenance complex component 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-24 Mcm10  minichromosome maintenance complex component 10  Mcm10  minichromosome maintenance deficient 10 (S. cerevisiae)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Mcm10  minichromosome maintenance deficient 10 (S. cerevisiae)   Mcm10_predicted  minichromosome maintenance deficient 10 (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mcm10_predicted  minichromosome maintenance deficient 10 (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED