Dcaf11 (DDB1 and CUL4 associated factor 11) - Rat Genome Database

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Pathways
Gene: Dcaf11 (DDB1 and CUL4 associated factor 11) Rattus norvegicus
Analyze
Symbol: Dcaf11
Name: DDB1 and CUL4 associated factor 11
RGD ID: 1311288
Description: Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within several processes, including exploration behavior; protein stabilization; and respiratory system process. Predicted to be located in nucleoplasm. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Orthologous to human DCAF11 (DDB1 and CUL4 associated factor 11); INTERACTS WITH (+)-schisandrin B; 3-chloropropane-1,2-diol; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DDB1- and CUL4-associated factor 11; LOC305895; MGC109419; MGC94719; WD repeat domain 23; WD repeat-containing protein 23; Wdr23
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,015,370 - 33,027,407 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1533,016,762 - 33,027,672 (+)EnsemblGRCr8
mRatBN7.21529,046,744 - 29,057,450 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,046,826 - 29,057,669 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1530,892,505 - 30,903,150 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,039,711 - 32,050,356 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,282,055 - 30,292,700 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,233,840 - 34,244,512 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,234,193 - 34,244,504 (+)Ensemblrn6Rnor6.0
Rnor_5.01538,124,048 - 38,134,707 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41533,691,576 - 33,701,328 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1528,622,724 - 28,633,369 (+)NCBICelera
RGSC_v3.11533,707,275 - 33,717,025 (+)NCBI
Cytogenetic Map15p13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amiodarone  (EXP)
aristolochic acid A  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP)
bortezomib  (ISO)
cadmium dichloride  (ISO)
caffeine  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
choline  (ISO)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diethylstilbestrol  (EXP)
diuron  (EXP)
fenthion  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
L-methionine  (ISO)
methapyrilene  (EXP,ISO)
methoxyacetic acid  (EXP)
methylmercury chloride  (EXP)
Monobutylphthalate  (EXP)
nefazodone  (EXP)
nitrates  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
silicon dioxide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16949367  


Genomics

Comparative Map Data
Dcaf11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,015,370 - 33,027,407 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1533,016,762 - 33,027,672 (+)EnsemblGRCr8
mRatBN7.21529,046,744 - 29,057,450 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,046,826 - 29,057,669 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1530,892,505 - 30,903,150 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,039,711 - 32,050,356 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,282,055 - 30,292,700 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,233,840 - 34,244,512 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,234,193 - 34,244,504 (+)Ensemblrn6Rnor6.0
Rnor_5.01538,124,048 - 38,134,707 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41533,691,576 - 33,701,328 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1528,622,724 - 28,633,369 (+)NCBICelera
RGSC_v3.11533,707,275 - 33,717,025 (+)NCBI
Cytogenetic Map15p13NCBI
DCAF11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,114,777 - 24,125,242 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,114,010 - 24,125,614 (+)Ensemblhg38GRCh38
GRCh371424,583,986 - 24,594,451 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,653,861 - 23,664,291 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341423,653,860 - 23,664,290NCBI
Celera144,448,376 - 4,458,921 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,699,126 - 4,709,671 (+)NCBIHuRef
CHM1_11424,582,565 - 24,593,110 (+)NCBICHM1_1
T2T-CHM13v2.01418,313,090 - 18,323,554 (+)NCBIT2T-CHM13v2.0
Dcaf11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,796,557 - 55,807,522 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,797,463 - 55,807,522 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381455,559,125 - 55,570,065 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,560,006 - 55,570,065 (+)Ensemblmm10GRCm38
MGSCv371456,178,869 - 56,188,902 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361454,514,103 - 54,524,136 (+)NCBIMGSCv36mm8
Celera1453,364,886 - 53,374,919 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Dcaf11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,272,184 - 36,279,872 (-)Ensembl
ChiLan1.0NW_00495540936,272,184 - 36,279,985 (-)NCBIChiLan1.0ChiLan1.0
DCAF11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,465,976 - 25,478,412 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,682,468 - 24,694,904 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,890,956 - 4,900,296 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11423,015,525 - 23,024,650 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,015,680 - 23,024,650 (+)EnsemblpanPan2panpan1.1
DCAF11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,115,756 - 4,124,329 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,116,912 - 4,123,596 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha84,037,424 - 4,045,984 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.084,226,332 - 4,234,902 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,226,712 - 4,234,912 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,916,964 - 3,925,526 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,978,716 - 3,987,276 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,240,837 - 4,249,445 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dcaf11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,966,258 - 35,974,161 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722414,831 - 422,694 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936722414,830 - 422,722 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCAF11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,168,992 - 75,180,953 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1775,169,701 - 75,181,137 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,442,389 - 80,452,269 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCAF11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,100,974 - 1,110,283 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,101,653 - 1,111,965 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603612,782,646 - 12,792,028 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcaf11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,407,596 - 8,415,295 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248208,407,597 - 8,415,301 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dcaf11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11269,440,807 - 69,451,239 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dcaf11
51 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:251
Count of miRNA genes:160
Interacting mature miRNAs:178
Transcripts:ENSRNOT00000059987
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat

Markers in Region
RH133568  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21529,057,430 - 29,057,635 (+)MAPPERmRatBN7.2
Rnor_6.01534,244,492 - 34,244,696NCBIRnor6.0
Rnor_5.01538,134,687 - 38,134,891UniSTSRnor5.0
RGSC_v3.41533,701,313 - 33,701,517UniSTSRGSC3.4
Celera1528,633,354 - 28,633,558UniSTS
RH 3.4 Map15260.81UniSTS
Cytogenetic Map15p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001009686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_073087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_073088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC081957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC091364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000059987   ⟹   ENSRNOP00000056736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1533,016,762 - 33,027,672 (+)Ensembl
mRatBN7.2 Ensembl1529,046,826 - 29,057,669 (+)Ensembl
Rnor_6.0 Ensembl1534,234,755 - 34,244,504 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077584   ⟹   ENSRNOP00000074435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1533,016,762 - 33,027,672 (+)Ensembl
mRatBN7.2 Ensembl1529,046,826 - 29,057,669 (+)Ensembl
Rnor_6.0 Ensembl1534,234,193 - 34,244,504 (+)Ensembl
RefSeq Acc Id: NM_001009686   ⟹   NP_001009686
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,017,655 - 33,027,407 (+)NCBI
mRatBN7.21529,047,695 - 29,057,446 (+)NCBI
Rnor_6.01534,234,755 - 34,244,507 (+)NCBI
Rnor_5.01538,124,048 - 38,134,707 (+)NCBI
RGSC_v3.41533,691,576 - 33,701,328 (+)RGD
Celera1528,623,617 - 28,633,369 (+)NCBI
Sequence:
RefSeq Acc Id: NR_073087
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,016,762 - 33,027,407 (+)NCBI
mRatBN7.21529,046,802 - 29,057,446 (+)NCBI
Rnor_6.01534,233,862 - 34,244,507 (+)NCBI
Rnor_5.01538,124,048 - 38,134,707 (+)NCBI
Celera1528,622,724 - 28,633,369 (+)NCBI
Sequence:
RefSeq Acc Id: NR_073088
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,016,762 - 33,027,407 (+)NCBI
mRatBN7.21529,046,802 - 29,057,446 (+)NCBI
Rnor_6.01534,233,862 - 34,244,507 (+)NCBI
Rnor_5.01538,124,048 - 38,134,707 (+)NCBI
Celera1528,622,724 - 28,633,369 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251971   ⟹   XP_006252033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,015,370 - 33,027,407 (+)NCBI
mRatBN7.21529,046,744 - 29,057,450 (+)NCBI
Rnor_6.01534,233,840 - 34,244,512 (+)NCBI
Rnor_5.01538,124,048 - 38,134,707 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599685   ⟹   XP_017455174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,015,370 - 33,027,407 (+)NCBI
mRatBN7.21529,046,744 - 29,057,450 (+)NCBI
Rnor_6.01534,233,840 - 34,244,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039093298   ⟹   XP_038949226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,015,370 - 33,027,407 (+)NCBI
mRatBN7.21529,046,744 - 29,057,450 (+)NCBI
RefSeq Acc Id: XM_039093299   ⟹   XP_038949227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,015,370 - 33,027,407 (+)NCBI
mRatBN7.21529,046,744 - 29,057,450 (+)NCBI
RefSeq Acc Id: XM_063274253   ⟹   XP_063130323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,015,370 - 33,027,407 (+)NCBI
RefSeq Acc Id: XM_063274254   ⟹   XP_063130324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,015,370 - 33,027,407 (+)NCBI
RefSeq Acc Id: XM_063274255   ⟹   XP_063130325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,015,370 - 33,027,407 (+)NCBI
RefSeq Acc Id: NP_001009686   ⟸   NM_001009686
- UniProtKB: Q5M9G8 (UniProtKB/Swiss-Prot),   A6KH09 (UniProtKB/TrEMBL),   A0A8L2QQZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252033   ⟸   XM_006251971
- Peptide Label: isoform X1
- UniProtKB: Q5M9G8 (UniProtKB/Swiss-Prot),   A6KH09 (UniProtKB/TrEMBL),   A0A8L2QQZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455174   ⟸   XM_017599685
- Peptide Label: isoform X1
- UniProtKB: Q5M9G8 (UniProtKB/Swiss-Prot),   A6KH09 (UniProtKB/TrEMBL),   A0A8L2QQZ0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000056736   ⟸   ENSRNOT00000059987
Ensembl Acc Id: ENSRNOP00000074435   ⟸   ENSRNOT00000077584
RefSeq Acc Id: XP_038949226   ⟸   XM_039093298
- Peptide Label: isoform X1
- UniProtKB: Q5M9G8 (UniProtKB/Swiss-Prot),   A6KH09 (UniProtKB/TrEMBL),   A0A8L2QQZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949227   ⟸   XM_039093299
- Peptide Label: isoform X1
- UniProtKB: Q5M9G8 (UniProtKB/Swiss-Prot),   A6KH09 (UniProtKB/TrEMBL),   A0A8L2QQZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130323   ⟸   XM_063274253
- Peptide Label: isoform X2
- UniProtKB: A6KH10 (UniProtKB/TrEMBL),   A0A8L2QQZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130324   ⟸   XM_063274254
- Peptide Label: isoform X2
- UniProtKB: A6KH10 (UniProtKB/TrEMBL),   A0A8L2QQZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130325   ⟸   XM_063274255
- Peptide Label: isoform X2
- UniProtKB: A6KH10 (UniProtKB/TrEMBL),   A0A8L2QQZ0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M9G8-F1-model_v2 AlphaFold Q5M9G8 1-549 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699670
Promoter ID:EPDNEW_R10193
Type:multiple initiation site
Name:Dcaf11_1
Description:DDB1 and CUL4 associated factor 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01534,234,791 - 34,234,851EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311288 AgrOrtholog
BioCyc Gene G2FUF-13716 BioCyc
Ensembl Genes ENSRNOG00000018825 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000077584 ENTREZGENE
  ENSRNOT00000077584.2 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7123958 IMAGE-MGC_LOAD
  IMAGE:7193336 IMAGE-MGC_LOAD
  IMAGE:7319156 IMAGE-MGC_LOAD
InterPro DCAF UniProtKB/Swiss-Prot
  DCAF11/LEC14B UniProtKB/Swiss-Prot
  G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:305895 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109419 IMAGE-MGC_LOAD
  MGC:94067 IMAGE-MGC_LOAD
  MGC:94719 IMAGE-MGC_LOAD
NCBI Gene 305895 ENTREZGENE
PANTHER DDB1- AND CUL4-ASSOCIATED FACTOR 11 UniProtKB/Swiss-Prot
  DDB1- AND CUL4-ASSOCIATED FACTOR 11 UniProtKB/Swiss-Prot
Pfam WD40 UniProtKB/Swiss-Prot
PhenoGen Dcaf11 PhenoGen
PIRSF WD_repeat_p23 UniProtKB/Swiss-Prot
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot
PROSITE WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018825 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A8L2QQZ0 ENTREZGENE, UniProtKB/TrEMBL
  A6KH09 ENTREZGENE, UniProtKB/TrEMBL
  A6KH10 ENTREZGENE, UniProtKB/TrEMBL
  DCA11_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Dcaf11  DDB1 and CUL4 associated factor 11  Wdr23  WD repeat domain 23  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Wdr23  WD repeat domain 23  Wdr23_predicted  WD repeat domain 23 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Wdr23_predicted  WD repeat domain 23 (predicted)      Symbol and Name status set to approved 70820 APPROVED