Myl9 (myosin light chain 9) - Rat Genome Database

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Gene: Myl9 (myosin light chain 9) Rattus norvegicus
Analyze
Symbol: Myl9
Name: myosin light chain 9
RGD ID: 1311235
Description: Predicted to enable myosin heavy chain binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in myofibril assembly and stress fiber assembly. Predicted to be located in Z disc. Predicted to be part of myosin II complex. Predicted to be active in myofibril and stress fiber. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy and megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human MYL9 (myosin light chain 9); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC296313; myosin regulatory light chain 2, smooth muscle isoform; myosin regulatory light chain 9; myosin regulatory light polypeptide 9; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83165,742,020 - 165,748,409 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3165,742,046 - 165,748,410 (+)EnsemblGRCr8
mRatBN7.23145,281,943 - 145,288,333 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3145,281,937 - 145,288,333 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3149,147,449 - 149,153,815 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03157,764,308 - 157,770,672 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03155,503,588 - 155,509,943 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03152,857,573 - 152,863,961 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3152,857,592 - 152,863,960 (+)Ensemblrn6Rnor6.0
Rnor_5.03158,832,628 - 158,839,014 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43147,190,252 - 147,193,865 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3144,001,709 - 144,005,322 (+)NCBICelera
RGSC_v3.13147,083,685 - 147,099,304 (+)NCBI
Cytogenetic Map3q42NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
Aescin  (EXP)
aflatoxin B1  (ISO)
alendronic acid  (EXP)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Arg-Gly-Asp  (ISO)
argipressin  (EXP)
aristolochic acid A  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
calmidazolium  (EXP)
calyculin A  (EXP)
captan  (ISO)
carbachol  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
cholic acid  (EXP)
choline  (ISO)
cisplatin  (EXP)
clofibrate  (ISO)
clotrimazole  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
curcumin  (ISO)
Cyanoginosin  (EXP)
cyclosporin A  (ISO)
D-mannitol  (EXP)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
desmopressin  (EXP)
dextran sulfate  (ISO)
dibenziodolium  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
Didecyldimethylammonium  (ISO)
diethyl malate  (ISO)
dioxygen  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
farnesol  (ISO)
fenamidone  (ISO)
folic acid  (ISO)
folpet  (ISO)
furan  (EXP)
geranylgeraniol  (ISO)
ginsenoside Re  (EXP)
glycodeoxycholic acid  (EXP)
graphene oxide  (ISO)
guanosine 5'-[gamma-thio]triphosphate  (EXP)
indoxyl sulfate  (ISO)
ionomycin  (EXP)
isobutanol  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (EXP,ISO)
maneb  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
microcystin-LR  (ISO)
ML-7  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nickel subsulfide  (EXP)
nifedipine  (EXP)
nitrates  (ISO)
Octicizer  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phlorizin  (EXP)
phorbol 12,13-dibutanoate  (EXP)
pioglitazone  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
quercitrin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (EXP)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
SKF-96365 hydrochloride  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triadimefon  (ISO)
triclosan  (ISO)
trifluoperazine  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
Y-27632  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell cortex  (IEA)
cytoplasm  (IBA)
cytoskeleton  (IEA)
myofibril  (IBA)
myosin complex  (IEA)
myosin II complex  (IBA,IEA,ISO)
stress fiber  (IBA,IEA,ISO)
Z disc  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. The E22K mutation of myosin RLC that causes familial hypertrophic cardiomyopathy increases calcium sensitivity of force and ATPase in transgenic mice. Szczesna-Cordary D, etal., J Cell Sci. 2005 Aug 15;118(Pt 16):3675-83. Epub 2005 Aug 2.
Additional References at PubMed
PMID:7733921   PMID:12477932   PMID:21126233   PMID:22003410   PMID:23382103   PMID:24825904   PMID:29476059   PMID:31505169   PMID:35352799  


Genomics

Comparative Map Data
Myl9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83165,742,020 - 165,748,409 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3165,742,046 - 165,748,410 (+)EnsemblGRCr8
mRatBN7.23145,281,943 - 145,288,333 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3145,281,937 - 145,288,333 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3149,147,449 - 149,153,815 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03157,764,308 - 157,770,672 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03155,503,588 - 155,509,943 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03152,857,573 - 152,863,961 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3152,857,592 - 152,863,960 (+)Ensemblrn6Rnor6.0
Rnor_5.03158,832,628 - 158,839,014 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43147,190,252 - 147,193,865 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3144,001,709 - 144,005,322 (+)NCBICelera
RGSC_v3.13147,083,685 - 147,099,304 (+)NCBI
Cytogenetic Map3q42NCBI
MYL9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382036,541,519 - 36,551,447 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2036,541,490 - 36,551,447 (+)Ensemblhg38GRCh38
GRCh372035,169,922 - 35,179,850 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362034,603,311 - 34,611,640 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342034,603,310 - 34,611,640NCBI
Celera2031,876,955 - 31,885,284 (+)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2031,906,489 - 31,914,828 (+)NCBIHuRef
CHM1_12035,071,604 - 35,079,943 (+)NCBICHM1_1
T2T-CHM13v2.02038,265,393 - 38,275,321 (+)NCBIT2T-CHM13v2.0
Myl9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392156,617,373 - 156,623,578 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2156,617,340 - 156,623,578 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382156,775,408 - 156,781,657 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2156,775,420 - 156,781,658 (+)Ensemblmm10GRCm38
MGSCv372156,601,200 - 156,607,393 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362156,466,480 - 156,473,099 (+)NCBIMGSCv36mm8
Celera2162,711,261 - 162,717,300 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map277.77NCBI
Myl9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542225,074,129 - 25,084,840 (-)Ensembl
ChiLan1.0NW_00495542225,078,011 - 25,084,853 (-)NCBIChiLan1.0ChiLan1.0
MYL9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22142,279,928 - 42,288,524 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12042,273,027 - 42,281,623 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02032,875,033 - 32,883,444 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12033,993,483 - 34,001,850 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2033,993,482 - 34,001,850 (+)EnsemblpanPan2panpan1.1
MYL9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12425,322,800 - 25,329,937 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2425,322,800 - 25,329,932 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2424,968,470 - 24,975,583 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02426,016,251 - 26,023,373 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2426,016,254 - 26,026,256 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12425,298,835 - 25,305,944 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02425,393,729 - 25,400,833 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02425,884,650 - 25,891,763 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Myl9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640174,264,092 - 174,271,149 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365614,475,021 - 4,485,463 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365614,478,400 - 4,485,457 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYL9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1739,788,199 - 39,795,293 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11739,788,165 - 39,795,240 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21745,264,926 - 45,272,001 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYL9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1257,397,836 - 57,405,856 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl257,397,874 - 57,406,630 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660873,890,131 - 3,898,141 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myl9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248422,975,987 - 2,982,953 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248422,975,992 - 2,982,956 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Myl9
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15136,118,109 - 136,124,527 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Myl9
37 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:200
Count of miRNA genes:130
Interacting mature miRNAs:153
Transcripts:ENSRNOT00000027445
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161799493176036425Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3141508991166376254Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3160357340167835660Rat

Markers in Region
RH140697  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23145,288,065 - 145,288,272 (+)MAPPERmRatBN7.2
Rnor_6.03152,863,694 - 152,863,900NCBIRnor6.0
Rnor_5.03158,832,689 - 158,832,895UniSTSRnor5.0
RGSC_v3.43147,193,600 - 147,193,806UniSTSRGSC3.4
Celera3144,005,057 - 144,005,263UniSTS
RH 3.4 Map31332.5UniSTS
Cytogenetic Map3q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 92 59 6 356 192 11 139 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001430178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC158548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S77900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000027445   ⟹   ENSRNOP00000027445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3165,742,046 - 165,748,410 (+)Ensembl
mRatBN7.2 Ensembl3145,281,937 - 145,288,333 (+)Ensembl
Rnor_6.0 Ensembl3152,857,592 - 152,863,960 (+)Ensembl
RefSeq Acc Id: NM_001100885   ⟹   NP_001094355
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83165,742,047 - 165,748,409 (+)NCBI
mRatBN7.23145,281,970 - 145,288,333 (+)NCBI
Rnor_6.03152,860,346 - 152,863,959 (+)NCBI
Rnor_5.03158,832,628 - 158,839,014 (-)NCBI
RGSC_v3.43147,190,252 - 147,193,865 (+)RGD
Celera3144,001,709 - 144,005,322 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235402   ⟹   XP_006235464
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83165,742,020 - 165,748,409 (+)NCBI
mRatBN7.23145,281,943 - 145,288,333 (+)NCBI
Rnor_6.03152,857,588 - 152,863,961 (+)NCBI
Rnor_5.03158,832,628 - 158,839,014 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001094355 (Get FASTA)   NCBI Sequence Viewer  
  NP_001417107 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235464 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB34127 (Get FASTA)   NCBI Sequence Viewer  
  AAI58549 (Get FASTA)   NCBI Sequence Viewer  
  EDL85838 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027445
GenBank Protein Q64122 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001094355   ⟸   NM_001100885
- UniProtKB: Q64122 (UniProtKB/Swiss-Prot),   B0BMS8 (UniProtKB/TrEMBL),   F7F3J1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235464   ⟸   XM_006235402
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000027445   ⟸   ENSRNOT00000027445
Protein Domains
EF-hand

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692603
Promoter ID:EPDNEW_R3127
Type:initiation region
Name:Myl9_1
Description:myosin light chain 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03152,857,638 - 152,857,698EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311235 AgrOrtholog
BioCyc Gene G2FUF-47084 BioCyc
Ensembl Genes ENSRNOG00000020246 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000027445 ENTREZGENE
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:9036351 IMAGE-MGC_LOAD
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  Myosin_RLC UniProtKB/Swiss-Prot
KEGG Report rno:296313 UniProtKB/Swiss-Prot
MGC_CLONE MGC:187199 IMAGE-MGC_LOAD
NCBI Gene 296313 ENTREZGENE
PANTHER MYOSIN REGULATORY LIGHT CHAIN 2 UniProtKB/Swiss-Prot
Pfam EF-hand_7 UniProtKB/Swiss-Prot
PhenoGen Myl9 PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020246 RatGTEx
SMART EFh UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt B0BMS8 ENTREZGENE, UniProtKB/TrEMBL
  F7F3J1 ENTREZGENE, UniProtKB/TrEMBL
  MYL9_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-10 Myl9  myosin light chain 9  Myl9  myosin, light chain 9, regulatory  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Myl9  myosin, light chain 9, regulatory  Myl9_predicted  myosin, light polypeptide 9, regulatory (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Myl9_predicted  myosin, light polypeptide 9, regulatory (predicted)      Symbol and Name status set to approved 70820 APPROVED