Dnai7 (dynein axonemal intermediate chain 7) - Rat Genome Database

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Pathways
Gene: Dnai7 (dynein axonemal intermediate chain 7) Rattus norvegicus
Analyze
Symbol: Dnai7
Name: dynein axonemal intermediate chain 7
RGD ID: 1311213
Description: Predicted to enable beta-tubulin binding activity and microtubule binding activity. Predicted to be located in cilium; cytoplasm; and microtubule cytoskeleton. Predicted to be part of axonemal dynein complex. Predicted to be active in axoneme and cytoplasmic microtubule. Orthologous to human DNAI7 (dynein axonemal intermediate chain 7); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cancer susceptibility 1; cancer susceptibility candidate 1; Casc1; Cfap94; cilia and flagella associated protein 94; dynein intermediate chain CFAP94, axonemal; Las1; LOC297720; lung adenoma susceptibility 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84179,874,338 - 179,910,716 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4179,873,522 - 179,910,780 (-)EnsemblGRCr8
mRatBN7.24178,143,499 - 178,179,871 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4178,143,500 - 178,179,980 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4184,444,178 - 184,480,647 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04180,228,678 - 180,265,147 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04178,849,095 - 178,885,568 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04179,440,984 - 179,476,965 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4179,440,953 - 179,477,070 (-)Ensemblrn6Rnor6.0
Rnor_5.04243,622,214 - 243,658,236 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44182,823,026 - 182,859,566 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4166,662,914 - 166,699,171 (-)NCBICelera
RGSC_v3.14183,068,145 - 183,104,849 (-)NCBI
Cytogenetic Map4q44NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. Liu P, etal., Nat Genet. 2006 Aug;38(8):888-95. Epub 2006 Jul 23.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Mechanisms promoting escape from mitotic stress-induced tumor cell death. Sinnott R, etal., Cancer Res. 2014 Jul 15;74(14):3857-69. doi: 10.1158/0008-5472.CAN-13-3398. Epub 2014 May 23.
7. Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice. Zhang Z, etal., Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12642-7. doi: 10.1073/pnas.2133947100.
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:17974961  


Genomics

Comparative Map Data
Dnai7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84179,874,338 - 179,910,716 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4179,873,522 - 179,910,780 (-)EnsemblGRCr8
mRatBN7.24178,143,499 - 178,179,871 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4178,143,500 - 178,179,980 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4184,444,178 - 184,480,647 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04180,228,678 - 180,265,147 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04178,849,095 - 178,885,568 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04179,440,984 - 179,476,965 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4179,440,953 - 179,477,070 (-)Ensemblrn6Rnor6.0
Rnor_5.04243,622,214 - 243,658,236 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44182,823,026 - 182,859,566 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4166,662,914 - 166,699,171 (-)NCBICelera
RGSC_v3.14183,068,145 - 183,104,849 (-)NCBI
Cytogenetic Map4q44NCBI
DNAI7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381225,107,047 - 25,195,160 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1225,108,289 - 25,195,163 (-)Ensemblhg38GRCh38
GRCh371225,261,223 - 25,348,094 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361225,152,490 - 25,239,361 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341225,152,489 - 25,239,361NCBI
Celera1230,408,204 - 30,495,049 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1225,031,916 - 25,118,815 (-)NCBIHuRef
CHM1_11225,226,353 - 25,313,239 (-)NCBICHM1_1
T2T-CHM13v2.01224,977,958 - 25,066,403 (-)NCBIT2T-CHM13v2.0
Dnai7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396145,120,556 - 145,156,866 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6145,120,560 - 145,156,731 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386145,174,833 - 145,211,017 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6145,174,834 - 145,211,005 (-)Ensemblmm10GRCm38
MGSCv376145,123,392 - 145,159,490 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366145,132,084 - 145,168,060 (-)NCBIMGSCv36mm8
Celera6148,249,078 - 148,285,257 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.37NCBI
Dnai7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541320,227,903 - 20,287,131 (-)Ensembl
ChiLan1.0NW_00495541320,227,807 - 20,287,211 (-)NCBIChiLan1.0ChiLan1.0
DNAI7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21071,620,868 - 71,707,847 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11271,617,264 - 71,704,233 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01261,117,886 - 61,204,888 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11263,733,801 - 63,819,991 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1263,733,785 - 63,819,991 (+)EnsemblpanPan2panpan1.1
DNAI7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12722,309,705 - 22,369,052 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2722,303,849 - 22,369,051 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2723,999,487 - 24,071,297 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02722,502,481 - 22,568,288 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2722,502,580 - 22,568,282 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12722,317,692 - 22,384,301 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02722,336,520 - 22,403,282 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02724,171,481 - 24,238,226 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dnai7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494584,200,357 - 84,274,388 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365482,123,360 - 2,202,032 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365482,123,248 - 2,197,245 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAI7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl548,555,688 - 48,651,365 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1548,555,637 - 48,651,370 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DNAI7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11124,871,767 - 24,953,586 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1124,875,416 - 24,953,375 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606910,173,735 - 10,255,300 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnai7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475213,855,426 - 13,936,764 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475213,855,328 - 13,932,210 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dnai7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v162,935,063 - 2,972,222 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dnai7
215 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:128
Count of miRNA genes:106
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000030680
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4176806581181925369Rat

Markers in Region
RH132020  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24178,143,532 - 178,143,724 (+)MAPPERmRatBN7.2
Rnor_6.04179,441,018 - 179,441,209NCBIRnor6.0
Rnor_5.04243,622,248 - 243,622,439UniSTSRnor5.0
RGSC_v3.44182,823,060 - 182,823,251UniSTSRGSC3.4
Celera4166,662,948 - 166,663,139UniSTS
RH 3.4 Map41066.7UniSTS
Cytogenetic Map4q44UniSTS
RH133694  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24178,165,429 - 178,165,620 (+)MAPPERmRatBN7.2
Rnor_6.04179,462,571 - 179,462,761NCBIRnor6.0
Rnor_5.04243,643,875 - 243,644,065UniSTSRnor5.0
RGSC_v3.44182,845,204 - 182,845,394UniSTSRGSC3.4
Celera4166,684,953 - 166,685,143UniSTS
RH 3.4 Map41066.9UniSTS
Cytogenetic Map4q44UniSTS
AA943468  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24178,180,185 - 178,180,307 (+)MAPPERmRatBN7.2
Rnor_6.04179,477,326 - 179,477,447NCBIRnor6.0
Rnor_5.04243,658,630 - 243,658,751UniSTSRnor5.0
RGSC_v3.44182,859,960 - 182,860,081UniSTSRGSC3.4
Celera4166,699,565 - 166,699,686UniSTS
RH 3.4 Map41077.3UniSTS
Cytogenetic Map4q44UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC160907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF546873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF562765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM388768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB695629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO386521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV108923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV722478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000030680   ⟹   ENSRNOP00000035058
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4179,874,339 - 179,910,780 (-)Ensembl
mRatBN7.2 Ensembl4178,143,500 - 178,179,980 (-)Ensembl
Rnor_6.0 Ensembl4179,440,953 - 179,477,070 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099666   ⟹   ENSRNOP00000090357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4179,873,522 - 179,910,780 (-)Ensembl
mRatBN7.2 Ensembl4178,143,500 - 178,173,415 (-)Ensembl
RefSeq Acc Id: NM_001106627   ⟹   NP_001100097
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,910,629 (-)NCBI
mRatBN7.24178,143,499 - 178,179,792 (-)NCBI
Rnor_6.04179,440,984 - 179,476,932 (-)NCBI
Rnor_5.04243,622,214 - 243,658,236 (-)NCBI
RGSC_v3.44182,823,026 - 182,859,566 (-)RGD
Celera4166,662,914 - 166,699,171 (-)RGD
Sequence:
RefSeq Acc Id: XM_039107466   ⟹   XP_038963394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,910,698 (-)NCBI
mRatBN7.24178,143,499 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107467   ⟹   XP_038963395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,910,698 (-)NCBI
mRatBN7.24178,143,499 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107468   ⟹   XP_038963396
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,899,691 (-)NCBI
mRatBN7.24178,143,499 - 178,168,849 (-)NCBI
RefSeq Acc Id: XM_039107469   ⟹   XP_038963397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,906,142 (-)NCBI
mRatBN7.24178,143,499 - 178,177,269 (-)NCBI
RefSeq Acc Id: XM_039107470   ⟹   XP_038963398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,910,716 (-)NCBI
mRatBN7.24178,143,499 - 178,179,871 (-)NCBI
RefSeq Acc Id: XM_039107472   ⟹   XP_038963400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,906,142 (-)NCBI
mRatBN7.24178,143,499 - 178,177,268 (-)NCBI
RefSeq Acc Id: XM_039107473   ⟹   XP_038963401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,910,710 (-)NCBI
mRatBN7.24178,143,499 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107474   ⟹   XP_038963402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,910,710 (-)NCBI
mRatBN7.24178,143,499 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107475   ⟹   XP_038963403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,910,698 (-)NCBI
mRatBN7.24178,150,479 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107476   ⟹   XP_038963404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,874,338 - 179,910,698 (-)NCBI
mRatBN7.24178,150,479 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107477   ⟹   XP_038963405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,880,406 - 179,910,698 (-)NCBI
mRatBN7.24178,149,567 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107478   ⟹   XP_038963406
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,886,444 - 179,910,698 (-)NCBI
mRatBN7.24178,160,198 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107479   ⟹   XP_038963407
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84179,884,526 - 179,910,698 (-)NCBI
mRatBN7.24178,153,688 - 178,179,865 (-)NCBI
RefSeq Acc Id: NP_001100097   ⟸   NM_001106627
- UniProtKB: B1H288 (UniProtKB/TrEMBL),   A0A8I6ACC4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035058   ⟸   ENSRNOT00000030680
RefSeq Acc Id: XP_038963398   ⟸   XM_039107470
- Peptide Label: isoform X5
- UniProtKB: A0A8I6ACC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963402   ⟸   XM_039107474
- Peptide Label: isoform X6
- UniProtKB: A0A8I6ACC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963401   ⟸   XM_039107473
- Peptide Label: isoform X4
- UniProtKB: A0A8I6ACC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963395   ⟸   XM_039107467
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ACC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963394   ⟸   XM_039107466
- Peptide Label: isoform X1
- UniProtKB: F7FKY0 (UniProtKB/TrEMBL),   A0A8I6ACC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963397   ⟸   XM_039107469
- Peptide Label: isoform X4
- UniProtKB: A0A8I6ACC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963400   ⟸   XM_039107472
- Peptide Label: isoform X6
- UniProtKB: A0A8I6ACC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963396   ⟸   XM_039107468
- Peptide Label: isoform X3
- UniProtKB: A0A8I6ACC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963405   ⟸   XM_039107477
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038963404   ⟸   XM_039107476
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038963403   ⟸   XM_039107475
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038963407   ⟸   XM_039107479
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038963406   ⟸   XM_039107478
- Peptide Label: isoform X10
Ensembl Acc Id: ENSRNOP00000090357   ⟸   ENSRNOT00000099666
Protein Domains
IC97/Casc1 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1H288-F1-model_v2 AlphaFold B1H288 1-730 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311213 AgrOrtholog
BioCyc Gene G2FUF-42459 BioCyc
Ensembl Genes ENSRNOG00000027630 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030680 ENTREZGENE
  ENSRNOT00000030680.7 UniProtKB/TrEMBL
  ENSRNOT00000099666.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7455489 IMAGE-MGC_LOAD
InterPro Casc1 UniProtKB/TrEMBL
  Casc1_N UniProtKB/TrEMBL
KEGG Report rno:297720 UniProtKB/TrEMBL
MGC_CLONE MGC:188640 IMAGE-MGC_LOAD
NCBI Gene 297720 ENTREZGENE
PANTHER DYNEIN AXONEMAL INTERMEDIATE CHAIN 7 UniProtKB/TrEMBL
  PTHR20929 UniProtKB/TrEMBL
Pfam Casc1_N UniProtKB/TrEMBL
PhenoGen Dnai7 PhenoGen
PRINTS CANCERSCCP1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000027630 RatGTEx
UniProt A0A8I6ACC4 ENTREZGENE, UniProtKB/TrEMBL
  B1H288 ENTREZGENE, UniProtKB/TrEMBL
  F7FKY0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-18 Dnai7  dynein axonemal intermediate chain 7  Cfap94  cilia and flagella associated protein 94  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2020-05-22 Cfap94  cilia and flagella associated protein 94  Casc1  cancer susceptibility 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-02-01 Casc1  cancer susceptibility 1  Casc1  cancer susceptibility candidate 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Casc1  cancer susceptibility candidate 1   Casc1_predicted  cancer susceptibility candidate 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Casc1_predicted  cancer susceptibility candidate 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED