Gene: Papln (papilin, proteoglycan-like sulfated glycoprotein) Rattus norvegicus
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Symbol:
Papln
Name:
papilin, proteoglycan-like sulfated glycoprotein
RGD ID:
1311176
Description:
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in extracellular matrix organization. Predicted to be located in basement membrane. Orthologous to human PAPLN (papilin, proteoglycan like sulfated glycoprotein); INTERACTS WITH 1-naphthyl isothiocyanate; atrazine; paracetamol.
Type:
protein-coding
RefSeq Status:
MODEL
Previously known as:
LOC314297; papilin
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
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Orthologs 1
Homo sapiens (human):
PAPLN (papilin, proteoglycan like sulfated glycoprotein)
HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):
Papln (papilin, proteoglycan-like sulfated glycoprotein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Papln (papilin, proteoglycan like sulfated glycoprotein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
PAPLN (papilin, proteoglycan like sulfated glycoprotein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
PAPLN (papilin, proteoglycan like sulfated glycoprotein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Papln (papilin, proteoglycan like sulfated glycoprotein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
PAPLN (papilin, proteoglycan like sulfated glycoprotein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
PAPLN (papilin, proteoglycan like sulfated glycoprotein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Papln (papilin, proteoglycan like sulfated glycoprotein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Papln (papilin, proteoglycan like sulfated glycoprotein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
CYP2B6 (cytochrome P450 family 2 subfamily B member 6)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
PAPLN (papilin, proteoglycan like sulfated glycoprotein)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
PAPLN (papilin, proteoglycan like sulfated glycoprotein)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Mus musculus (house mouse):
Papln (papilin, proteoglycan-like sulfated glycoprotein)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
paplna (papilin a, proteoglycan-like sulfated glycoprotein)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
paplna (papilin a, proteoglycan-like sulfated glycoprotein)
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
paplnb (papilin b, proteoglycan-like sulfated glycoprotein)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
mig-6
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
mig-6
Alliance
DIOPT (Ensembl Compara|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Ppn
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Ppn
Alliance
DIOPT (Ensembl Compara|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
papln
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
papln
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 6 109,129,268 - 109,163,300 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 6 109,129,261 - 109,161,483 (+) Ensembl GRCr8 mRatBN7.2 6 103,398,166 - 103,432,199 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 6 103,398,838 - 103,432,206 (+) Ensembl mRatBN7.2 Rnor_6.0 6 107,245,573 - 107,282,256 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 6 107,245,820 - 107,276,755 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 6 118,263,779 - 118,296,813 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 6 107,805,057 - 107,835,170 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 6 101,226,540 - 101,260,943 (+) NCBI Celera RGSC_v3.1 6 107,806,932 - 107,838,313 (+) NCBI Cytogenetic Map 6 q31 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Papln Rat (1->4)-beta-D-glucan multiple interactions ISO Papln (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PAPLN mRNA CTD PMID:36331819 Papln Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Papln (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Papln Rat 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of PAPLN mRNA CTD PMID:30723492 Papln Rat 17beta-estradiol increases expression ISO Papln (Mus musculus) 6480464 Estradiol results in increased expression of PAPLN mRNA CTD PMID:19484750 Papln Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Papln (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Papln Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Papln (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Papln Rat 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO Papln (Mus musculus) 6480464 2,3',4,4',5-pentachlorobiphenyl results in increased expression of PAPLN mRNA CTD PMID:31388691 Papln Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Papln (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Papln Rat 4,4'-sulfonyldiphenol decreases methylation ISO PAPLN (Homo sapiens) 6480464 bisphenol S results in decreased methylation of PAPLN gene CTD PMID:31601247 Papln Rat 5-aza-2'-deoxycytidine affects expression ISO PAPLN (Homo sapiens) 6480464 Decitabine affects the expression of PAPLN mRNA CTD PMID:23300844 Papln Rat acrylamide decreases expression ISO PAPLN (Homo sapiens) 6480464 Acrylamide results in decreased expression of PAPLN mRNA CTD PMID:32763439 Papln Rat aflatoxin B1 increases methylation ISO PAPLN (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of PAPLN intron CTD PMID:30157460 Papln Rat Aflatoxin B2 alpha decreases methylation ISO PAPLN (Homo sapiens) 6480464 aflatoxin B2 results in decreased methylation of PAPLN intron CTD PMID:30157460 Papln Rat all-trans-retinoic acid decreases expression ISO PAPLN (Homo sapiens) 6480464 Tretinoin results in decreased expression of PAPLN mRNA CTD PMID:21934132 Papln Rat aristolochic acid A decreases expression ISO PAPLN (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of PAPLN mRNA CTD PMID:33212167 Papln Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of PAPLN gene CTD PMID:35440735 Papln Rat benzo[a]pyrene decreases expression ISO Papln (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of PAPLN mRNA CTD PMID:22228805 Papln Rat benzo[a]pyrene decreases methylation ISO PAPLN (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of PAPLN 5' UTR; Benzo(a)pyrene results in decreased methylation of more ... CTD PMID:27901495 Papln Rat benzo[a]pyrene affects methylation ISO PAPLN (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PAPLN intron CTD PMID:30157460 Papln Rat benzo[e]pyrene increases methylation ISO PAPLN (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of PAPLN intron CTD PMID:30157460 Papln Rat bis(2-ethylhexyl) phthalate decreases expression ISO PAPLN (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of PAPLN mRNA CTD PMID:31163220 Papln Rat bis(2-ethylhexyl) phthalate increases expression ISO Papln (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of PAPLN mRNA CTD PMID:34319233 Papln Rat bisphenol A increases expression ISO Papln (Mus musculus) 6480464 bisphenol A results in increased expression of PAPLN mRNA CTD PMID:30245210|PMID:32156529 Papln Rat bisphenol A increases methylation ISO PAPLN (Homo sapiens) 6480464 bisphenol A results in increased methylation of PAPLN gene CTD PMID:31601247 Papln Rat bisphenol F affects expression ISO Papln (Mus musculus) 6480464 bisphenol F affects the expression of PAPLN mRNA CTD PMID:38685157 Papln Rat cadmium dichloride decreases expression ISO PAPLN (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of PAPLN mRNA CTD PMID:38568856 Papln Rat CGP 52608 multiple interactions ISO PAPLN (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PAPLN gene] CTD PMID:28238834 Papln Rat chlorpyrifos increases expression ISO Papln (Mus musculus) 6480464 Chlorpyrifos results in increased expression of PAPLN mRNA CTD PMID:37019170 Papln Rat cisplatin multiple interactions ISO PAPLN (Homo sapiens) 6480464 [Cisplatin co-treated with Paclitaxel] results in decreased expression of PAPLN mRNA CTD PMID:20705681 Papln Rat cisplatin affects expression ISO PAPLN (Homo sapiens) 6480464 Cisplatin affects the expression of PAPLN mRNA CTD PMID:23300844 Papln Rat copper(II) chloride decreases expression ISO PAPLN (Homo sapiens) 6480464 cupric chloride results in decreased expression of PAPLN mRNA CTD PMID:38568856 Papln Rat Dibutyl phosphate affects expression ISO PAPLN (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of PAPLN mRNA CTD PMID:37042841 Papln Rat dorsomorphin multiple interactions ISO PAPLN (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Papln Rat entinostat increases expression ISO PAPLN (Homo sapiens) 6480464 entinostat results in increased expression of PAPLN mRNA CTD PMID:26272509 Papln Rat ethanol increases expression ISO Papln (Mus musculus) 6480464 Ethanol results in increased expression of PAPLN mRNA CTD PMID:30319688 Papln Rat ethyl methanesulfonate increases expression ISO PAPLN (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of PAPLN mRNA CTD PMID:23649840 Papln Rat ethylbenzene multiple interactions ISO PAPLN (Homo sapiens) 6480464 [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of PAPLN mRNA; [Toluene more ... CTD PMID:26018793 Papln Rat folic acid increases expression ISO Papln (Mus musculus) 6480464 Folic Acid results in increased expression of PAPLN mRNA CTD PMID:25629700 Papln Rat formaldehyde increases expression ISO PAPLN (Homo sapiens) 6480464 Formaldehyde results in increased expression of PAPLN mRNA CTD PMID:23649840 Papln Rat mercury dibromide decreases expression ISO PAPLN (Homo sapiens) 6480464 mercuric bromide results in decreased expression of PAPLN mRNA CTD PMID:26272509 Papln Rat mercury dibromide multiple interactions ISO PAPLN (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Papln Rat methapyrilene increases methylation ISO PAPLN (Homo sapiens) 6480464 Methapyrilene results in increased methylation of PAPLN intron CTD PMID:30157460 Papln Rat methyl methanesulfonate increases expression ISO PAPLN (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of PAPLN mRNA CTD PMID:23649840 Papln Rat methylmercury chloride decreases expression ISO PAPLN (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of PAPLN mRNA CTD PMID:28001369 Papln Rat nickel atom decreases expression ISO PAPLN (Homo sapiens) 6480464 Nickel results in decreased expression of PAPLN mRNA CTD PMID:24768652|PMID:25583101 Papln Rat okadaic acid decreases expression ISO PAPLN (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of PAPLN mRNA CTD PMID:38832940 Papln Rat p-chloromercuribenzoic acid decreases expression ISO PAPLN (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in decreased expression of PAPLN mRNA CTD PMID:26272509 Papln Rat p-chloromercuribenzoic acid multiple interactions ISO PAPLN (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Papln Rat paclitaxel multiple interactions ISO PAPLN (Homo sapiens) 6480464 [Cisplatin co-treated with Paclitaxel] results in decreased expression of PAPLN mRNA CTD PMID:20705681 Papln Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of PAPLN mRNA CTD PMID:30723492 Papln Rat PCB138 multiple interactions ISO Papln (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Papln Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Papln (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PAPLN mRNA CTD PMID:36331819 Papln Rat phenylmercury acetate decreases expression ISO PAPLN (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of PAPLN mRNA CTD PMID:26272509 Papln Rat phenylmercury acetate multiple interactions ISO PAPLN (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Papln Rat pirinixic acid multiple interactions ISO Papln (Mus musculus) 6480464 [pirinixic acid co-treated with PPARA] results in increased expression of PAPLN mRNA CTD PMID:20813756 Papln Rat pirinixic acid increases expression ISO Papln (Mus musculus) 6480464 pirinixic acid results in increased expression of PAPLN mRNA CTD PMID:20813756 Papln Rat resveratrol multiple interactions ISO PAPLN (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of PAPLN mRNA CTD PMID:23557933 Papln Rat SB 431542 multiple interactions ISO PAPLN (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Papln Rat silicon dioxide increases expression ISO PAPLN (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of PAPLN mRNA CTD PMID:25895662 Papln Rat sodium arsenite increases expression ISO Papln (Mus musculus) 6480464 sodium arsenite results in increased expression of PAPLN mRNA CTD PMID:16014739 Papln Rat sodium arsenite decreases expression ISO Papln (Mus musculus) 6480464 sodium arsenite results in decreased expression of PAPLN mRNA CTD PMID:37682722 Papln Rat sodium arsenite decreases expression ISO PAPLN (Homo sapiens) 6480464 sodium arsenite results in decreased expression of PAPLN mRNA CTD PMID:38568856 Papln Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of PAPLN mRNA CTD PMID:34492290 Papln Rat toluene multiple interactions ISO PAPLN (Homo sapiens) 6480464 [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of PAPLN mRNA; [Toluene more ... CTD PMID:26018793 Papln Rat trichostatin A decreases expression ISO PAPLN (Homo sapiens) 6480464 trichostatin A results in decreased expression of PAPLN mRNA CTD PMID:24935251|PMID:26272509 Papln Rat trichostatin A multiple interactions ISO PAPLN (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Papln Rat triphenyl phosphate affects expression ISO PAPLN (Homo sapiens) 6480464 triphenyl phosphate affects the expression of PAPLN mRNA CTD PMID:37042841 Papln Rat valproic acid increases methylation ISO PAPLN (Homo sapiens) 6480464 Valproic Acid results in increased methylation of PAPLN gene CTD PMID:29154799 Papln Rat valproic acid affects expression ISO Papln (Mus musculus) 6480464 Valproic Acid affects the expression of PAPLN mRNA CTD PMID:17963808 Papln Rat valproic acid decreases expression ISO PAPLN (Homo sapiens) 6480464 Valproic Acid results in decreased expression of PAPLN mRNA CTD PMID:24383497|PMID:28001369|PMID:29154799