Aktip (AKT interacting protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Aktip (AKT interacting protein) Rattus norvegicus
Analyze
Symbol: Aktip
Name: AKT interacting protein
RGD ID: 1311170
Description: Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in several processes, including early endosome to late endosome transport; protein K63-linked ubiquitination; and protein localization to perinuclear region of cytoplasm. Predicted to be located in plasma membrane. Predicted to be part of FHF complex and HOPS complex. Predicted to be active in nucleus. Orthologous to human AKTIP (AKT interacting protein); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: AKT-interacting protein; Fts; fused toes; fused toes protein homolog; LOC291906; MGC109405
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81932,039,507 - 32,059,634 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1932,039,466 - 32,067,178 (+)EnsemblGRCr8
mRatBN7.21915,866,811 - 15,877,123 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1915,866,928 - 15,886,663 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1917,555,540 - 17,565,425 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01922,750,095 - 22,759,980 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01925,697,676 - 25,707,547 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01917,290,048 - 17,300,054 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1917,290,178 - 17,300,050 (+)Ensemblrn6Rnor6.0
Rnor_5.01928,354,053 - 28,373,178 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41917,035,220 - 17,045,096 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1915,772,238 - 15,782,114 (+)NCBICelera
RGSC_v3.11917,040,045 - 17,049,918 (+)NCBI
Cytogenetic Map19p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bisphenol A  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diazinon  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
ethanol  (ISO)
fenthion  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methidathion  (ISO)
methylmercury chloride  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA,ISO)
FHF complex  (IEA,ISO,ISS)
HOPS complex  (IEA,ISO)
nucleus  (IBA)
plasma membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14749367   PMID:18799622  


Genomics

Comparative Map Data
Aktip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81932,039,507 - 32,059,634 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1932,039,466 - 32,067,178 (+)EnsemblGRCr8
mRatBN7.21915,866,811 - 15,877,123 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1915,866,928 - 15,886,663 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1917,555,540 - 17,565,425 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01922,750,095 - 22,759,980 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01925,697,676 - 25,707,547 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01917,290,048 - 17,300,054 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1917,290,178 - 17,300,050 (+)Ensemblrn6Rnor6.0
Rnor_5.01928,354,053 - 28,373,178 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41917,035,220 - 17,045,096 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1915,772,238 - 15,782,114 (+)NCBICelera
RGSC_v3.11917,040,045 - 17,049,918 (+)NCBI
Cytogenetic Map19p11NCBI
AKTIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381653,491,040 - 53,504,412 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1653,490,502 - 53,504,411 (-)Ensemblhg38GRCh38
GRCh371653,524,952 - 53,537,121 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361652,082,693 - 52,094,671 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341652,083,103 - 52,094,652NCBI
Celera1638,040,003 - 38,051,981 (-)NCBICelera
Cytogenetic Map16q12.2NCBI
HuRef1639,412,663 - 39,424,641 (-)NCBIHuRef
CHM1_11654,932,327 - 54,944,305 (-)NCBICHM1_1
T2T-CHM13v2.01659,288,844 - 59,302,210 (-)NCBIT2T-CHM13v2.0
Aktip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39891,834,267 - 91,862,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl891,838,412 - 91,926,604 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38891,111,781 - 91,135,494 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl891,111,784 - 91,199,976 (-)Ensemblmm10GRCm38
MGSCv37893,647,398 - 93,659,395 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36894,013,604 - 94,025,601 (-)NCBIMGSCv36mm8
Celera895,438,579 - 95,450,369 (-)NCBICelera
Cytogenetic Map8C4NCBI
cM Map844.25NCBI
Aktip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543311,237,717 - 11,248,249 (-)Ensembl
ChiLan1.0NW_00495543311,237,717 - 11,248,638 (-)NCBIChiLan1.0ChiLan1.0
AKTIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21862,926,407 - 62,937,985 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11668,845,024 - 68,856,614 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01633,731,652 - 33,743,571 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11652,815,573 - 52,827,807 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1652,815,559 - 52,827,750 (-)EnsemblpanPan2panpan1.1
AKTIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1262,253,005 - 62,263,918 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl262,254,320 - 62,263,337 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha258,886,060 - 58,896,994 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0262,794,743 - 62,805,677 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl262,796,373 - 62,805,992 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1259,618,363 - 59,629,310 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0260,638,932 - 60,649,878 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0261,521,329 - 61,532,263 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Aktip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934953,438,840 - 53,449,200 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364756,139,875 - 6,150,130 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364756,139,875 - 6,150,132 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKTIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl631,747,606 - 31,758,279 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1631,706,253 - 31,757,878 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AKTIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1539,283,607 - 39,295,320 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl539,284,308 - 39,295,284 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604737,085,946 - 37,097,680 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aktip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247573,265,389 - 3,294,735 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247573,265,492 - 3,295,406 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Aktip
78 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:388
Count of miRNA genes:242
Interacting mature miRNAs:293
Transcripts:ENSRNOT00000060865
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat

Markers in Region
RH142012  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21915,876,718 - 15,876,928 (+)MAPPERmRatBN7.2
Rnor_6.01917,299,955 - 17,300,164NCBIRnor6.0
Rnor_5.01928,364,067 - 28,364,276UniSTSRnor5.0
RGSC_v3.41917,044,997 - 17,045,206UniSTSRGSC3.4
Celera1915,782,015 - 15,782,224UniSTS
Cytogenetic Map19p11UniSTS
AI501448  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21915,871,750 - 15,871,943 (+)MAPPERmRatBN7.2
Rnor_6.01917,294,987 - 17,295,179NCBIRnor6.0
Rnor_5.01928,359,099 - 28,359,291UniSTSRnor5.0
RGSC_v3.41917,040,029 - 17,040,221UniSTSRGSC3.4
Celera1915,777,047 - 15,777,239UniSTS
Cytogenetic Map19p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000060865   ⟹   ENSRNOP00000057588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1932,039,769 - 32,050,022 (+)Ensembl
mRatBN7.2 Ensembl1915,866,928 - 15,877,121 (+)Ensembl
Rnor_6.0 Ensembl1917,290,178 - 17,300,050 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108713   ⟹   ENSRNOP00000091269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1932,039,983 - 32,048,986 (+)Ensembl
mRatBN7.2 Ensembl1915,867,224 - 15,877,121 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109943   ⟹   ENSRNOP00000092612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1932,039,802 - 32,059,913 (+)Ensembl
mRatBN7.2 Ensembl1915,866,939 - 15,886,663 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113279   ⟹   ENSRNOP00000082936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1932,039,466 - 32,049,957 (+)Ensembl
mRatBN7.2 Ensembl1915,870,699 - 15,877,119 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121379   ⟹   ENSRNOP00000111489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1932,039,769 - 32,067,178 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000143979   ⟹   ENSRNOP00000105243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1932,039,765 - 32,053,865 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000173884   ⟹   ENSRNOP00000105473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1932,043,537 - 32,053,865 (+)Ensembl
RefSeq Acc Id: NM_001011926   ⟹   NP_001011926
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,780 - 32,049,656 (+)NCBI
mRatBN7.21915,866,941 - 15,876,818 (+)NCBI
Rnor_6.01917,290,178 - 17,300,054 (+)NCBI
Rnor_5.01928,354,053 - 28,373,178 (+)NCBI
RGSC_v3.41917,035,220 - 17,045,096 (+)RGD
Celera1915,772,238 - 15,782,114 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255182   ⟹   XP_006255244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,746 - 32,049,656 (+)NCBI
mRatBN7.21915,866,907 - 15,876,808 (+)NCBI
Rnor_6.01917,290,177 - 17,300,054 (+)NCBI
Rnor_5.01928,354,053 - 28,373,178 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601205   ⟹   XP_017456694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,507 - 32,049,656 (+)NCBI
mRatBN7.21915,866,811 - 15,876,808 (+)NCBI
Rnor_6.01917,290,048 - 17,300,054 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601206   ⟹   XP_017456695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,567 - 32,049,656 (+)NCBI
mRatBN7.21915,866,811 - 15,876,818 (+)NCBI
Rnor_6.01917,290,048 - 17,300,054 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097569   ⟹   XP_038953497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,042,422 - 32,049,656 (+)NCBI
mRatBN7.21915,866,941 - 15,876,818 (+)NCBI
RefSeq Acc Id: XM_063277863   ⟹   XP_063133933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,993 - 32,049,656 (+)NCBI
RefSeq Acc Id: XM_063277864   ⟹   XP_063133934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,991 - 32,049,656 (+)NCBI
RefSeq Acc Id: XM_063277865   ⟹   XP_063133935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,999 - 32,059,634 (+)NCBI
RefSeq Acc Id: NP_001011926   ⟸   NM_001011926
- UniProtKB: Q5FVH4 (UniProtKB/Swiss-Prot),   A6KD80 (UniProtKB/TrEMBL),   A0A8I6GA43 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255244   ⟸   XM_006255182
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AQ33 (UniProtKB/TrEMBL),   A0A8I6GA43 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456694   ⟸   XM_017601205
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GA43 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456695   ⟸   XM_017601206
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GA43 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000057588   ⟸   ENSRNOT00000060865
RefSeq Acc Id: XP_038953497   ⟸   XM_039097569
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000091269   ⟸   ENSRNOT00000108713
Ensembl Acc Id: ENSRNOP00000082936   ⟸   ENSRNOT00000113279
Ensembl Acc Id: ENSRNOP00000092612   ⟸   ENSRNOT00000109943
RefSeq Acc Id: XP_063133934   ⟸   XM_063277864
- Peptide Label: isoform X4
- UniProtKB: Q5FVH4 (UniProtKB/Swiss-Prot),   A6KD80 (UniProtKB/TrEMBL),   A0A8I6GA43 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133933   ⟸   XM_063277863
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AQ33 (UniProtKB/TrEMBL),   A0A8I6GA43 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133935   ⟸   XM_063277865
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AI00 (UniProtKB/TrEMBL),   A6KD77 (UniProtKB/TrEMBL),   A0A8I6GA43 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111489   ⟸   ENSRNOT00000121379
Ensembl Acc Id: ENSRNOP00000105243   ⟸   ENSRNOT00000143979
Ensembl Acc Id: ENSRNOP00000105473   ⟸   ENSRNOT00000173884
Protein Domains
UBC core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FVH4-F1-model_v2 AlphaFold Q5FVH4 1-292 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700973
Promoter ID:EPDNEW_R11496
Type:initiation region
Name:Aktip_1
Description:AKT interacting protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01917,290,169 - 17,290,229EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311170 AgrOrtholog
BioCyc Gene G2FUF-6360 BioCyc
Ensembl Genes ENSRNOG00000011956 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000108713 ENTREZGENE
  ENSRNOT00000109943 ENTREZGENE
  ENSRNOT00000113279 ENTREZGENE
  ENSRNOT00000143979 ENTREZGENE
Gene3D-CATH 3.10.110.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7318380 IMAGE-MGC_LOAD
InterPro Ub_conjugating_enzyme UniProtKB/Swiss-Prot
  UBQ-conjugat_E2 UniProtKB/Swiss-Prot
  UBQ-conjugating_enzyme/RWD UniProtKB/Swiss-Prot
KEGG Report rno:291906 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109405 IMAGE-MGC_LOAD
NCBI Gene 291906 ENTREZGENE
PANTHER UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/Swiss-Prot
Pfam UQ_con UniProtKB/Swiss-Prot
PhenoGen Aktip PhenoGen
PROSITE UBIQUITIN_CONJUGAT_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011956 RatGTEx
SMART UBCc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54495 UniProtKB/Swiss-Prot
UniProt A0A8I6AI00 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQ33 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GA43 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QUG0_RAT UniProtKB/TrEMBL
  A0ABK0LIF4_RAT UniProtKB/TrEMBL
  A0ABK0M3B9_RAT UniProtKB/TrEMBL
  A6KD77 ENTREZGENE, UniProtKB/TrEMBL
  A6KD80 ENTREZGENE, UniProtKB/TrEMBL
  AKTIP_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-20 Aktip  AKT interacting protein  Fts  fused toes  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Fts  fused toes  Fts_predicted  fused toes (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Fts_predicted  fused toes (predicted)      Symbol and Name status set to approved 70820 APPROVED