Ap3s1 (adaptor related protein complex 3 subunit sigma 1) - Rat Genome Database

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Gene: Ap3s1 (adaptor related protein complex 3 subunit sigma 1) Rattus norvegicus
Analyze
Symbol: Ap3s1
Name: adaptor related protein complex 3 subunit sigma 1
RGD ID: 1311115
Description: Predicted to be involved in anterograde synaptic vesicle transport and vesicle-mediated transport. Is active in synaptic vesicle. Orthologous to human AP3S1 (adaptor related protein complex 3 subunit sigma 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adaptor-related protein complex 3, sigma 1 subunit; AP-3 complex subunit sigma-1; LOC302290
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81841,649,321 - 41,718,221 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1841,648,796 - 41,767,641 (+)EnsemblGRCr8
mRatBN7.21839,462,728 - 39,531,622 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1839,462,765 - 39,531,622 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1841,495,983 - 41,564,832 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01842,198,228 - 42,267,061 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01839,991,330 - 40,060,182 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01840,732,472 - 40,798,064 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1840,732,480 - 40,797,761 (+)Ensemblrn6Rnor6.0
Rnor_5.01840,378,507 - 40,443,852 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41840,944,324 - 41,016,397 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1837,714,203 - 37,782,243 (+)NCBICelera
RGSC_v3.11840,981,868 - 41,053,916 (+)NCBI
Cytogenetic Map18q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Hidden proteome of synaptic vesicles in the mammalian brain. Taoufiq Z, etal., Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33586-33596. doi: 10.1073/pnas.2011870117. Epub 2020 Dec 21.
Additional References at PubMed
PMID:9118953   PMID:12477932   PMID:16837549   PMID:21998198  


Genomics

Comparative Map Data
Ap3s1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81841,649,321 - 41,718,221 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1841,648,796 - 41,767,641 (+)EnsemblGRCr8
mRatBN7.21839,462,728 - 39,531,622 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1839,462,765 - 39,531,622 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1841,495,983 - 41,564,832 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01842,198,228 - 42,267,061 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01839,991,330 - 40,060,182 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01840,732,472 - 40,798,064 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1840,732,480 - 40,797,761 (+)Ensemblrn6Rnor6.0
Rnor_5.01840,378,507 - 40,443,852 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41840,944,324 - 41,016,397 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1837,714,203 - 37,782,243 (+)NCBICelera
RGSC_v3.11840,981,868 - 41,053,916 (+)NCBI
Cytogenetic Map18q11NCBI
AP3S1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385115,841,935 - 115,914,081 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5115,841,422 - 115,914,086 (+)Ensemblhg38GRCh38
GRCh375115,177,632 - 115,249,778 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,205,518 - 115,277,677 (+)NCBIBuild 36Build 36hg18NCBI36
Build 345115,205,517 - 115,277,675NCBI
Celera5111,126,032 - 111,198,189 (+)NCBICelera
Cytogenetic Map5q22.3-q23.1NCBI
HuRef5110,358,321 - 110,430,486 (+)NCBIHuRef
CHM1_15114,610,262 - 114,682,389 (+)NCBICHM1_1
T2T-CHM13v2.05116,354,331 - 116,426,478 (+)NCBIT2T-CHM13v2.0
Ap3s1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391846,874,761 - 46,923,893 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1846,874,943 - 46,923,893 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381846,741,694 - 46,790,826 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1846,741,876 - 46,790,826 (+)Ensemblmm10GRCm38
MGSCv371846,901,571 - 46,950,480 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361846,867,258 - 46,915,950 (+)NCBIMGSCv36mm8
Celera1848,101,214 - 48,150,159 (+)NCBICelera
Cytogenetic Map18CNCBI
cM Map1824.77NCBI
Ap3s1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540835,621,062 - 35,680,683 (+)Ensembl
ChiLan1.0NW_00495540835,621,062 - 35,680,620 (+)NCBIChiLan1.0ChiLan1.0
AP3S1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24111,086,333 - 111,158,858 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15109,240,241 - 109,312,426 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05111,195,900 - 111,268,129 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15116,992,049 - 117,063,727 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5116,992,049 - 117,063,727 (+)EnsemblpanPan2panpan1.1
AP3S1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1115,543,140 - 5,611,322 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl115,543,222 - 5,610,930 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha115,693,755 - 5,761,939 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0115,534,942 - 5,603,128 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl115,534,909 - 5,603,128 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1115,490,133 - 5,558,288 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0115,561,315 - 5,629,497 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0115,813,527 - 5,881,722 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ap3s1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213128,306,979 - 128,387,501 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367421,007,973 - 1,088,394 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367421,007,684 - 1,088,272 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AP3S1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2119,965,539 - 120,039,947 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12119,965,539 - 120,039,948 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22124,908,907 - 124,942,828 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AP3S1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12319,087,684 - 19,158,201 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2319,087,698 - 19,150,979 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603459,250,651 - 59,321,438 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ap3s1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247335,979,734 - 6,045,721 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247335,979,644 - 6,045,777 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ap3s1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11540,252,086 - 40,310,935 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ap3s1
434 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:65
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000064116
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)182201556261600538Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)183857591983575919Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182682218671822186Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182682218671822186Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182682218671822186Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050563968306Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182682218671822186Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182682218671822186Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182682218671822186Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183199089176990891Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183161050585493247Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)183337915878379158Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)184046238385462383Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18448264849482648Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183199089176990891Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18154490981Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
11565454Kidm59Kidney mass QTL 590.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)18706572852065728Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)18430735449307354Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)183337915878379158Rat
2301409Cm70Cardiac mass QTL 700.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)18706572852065728Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)183337915878379158Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)183337915878379158Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182682218671822186Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183152278376522783Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)183337915878379158Rat
12904716Am21Aortic mass QTL 210.005aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)18706572852065728Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183337915878379158Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)183337915878379158Rat
12904714Cm131Cardiac mass QTL 1310.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)18706572852065728Rat
12904715Cm132Cardiac mass QTL 1320.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)18706572852065728Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183161050577371277Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183612162681121626Rat
6903345Bp349Blood pressure QTL 3493.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181522610142690662Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)183199089176990891Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18546045542690191Rat
6903349Bp351Blood pressure QTL 3513.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)182641582171415821Rat
6903351Bp352Blood pressure QTL 3523.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183164450879484311Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18144930869Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181206648257066482Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183199089176990891Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183161050572538878Rat

Markers in Region
D18Got124  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21839,494,895 - 39,495,097 (+)MAPPERmRatBN7.2
Rnor_6.01840,762,525 - 40,762,726NCBIRnor6.0
Rnor_5.01840,408,565 - 40,408,766UniSTSRnor5.0
RGSC_v3.41840,979,216 - 40,979,417UniSTSRGSC3.4
Celera1837,745,534 - 37,745,735UniSTS
Cytogenetic Map18q11UniSTS
RH138037  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21839,461,446 - 39,461,595 (+)MAPPERmRatBN7.2
Rnor_6.01840,731,149 - 40,731,297NCBIRnor6.0
Rnor_5.01840,377,176 - 40,377,324UniSTSRnor5.0
RGSC_v3.41840,942,993 - 40,943,141UniSTSRGSC3.4
Celera1837,712,872 - 37,713,020UniSTS
Cytogenetic Map18q11UniSTS
RH138166  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21839,527,854 - 39,528,031 (+)MAPPERmRatBN7.2
Rnor_6.01840,793,990 - 40,794,166NCBIRnor6.0
Rnor_5.01840,440,081 - 40,440,257UniSTSRnor5.0
RGSC_v3.41841,012,626 - 41,012,802UniSTSRGSC3.4
Celera1837,778,472 - 37,778,648UniSTS
Cytogenetic Map18q11UniSTS
PMC166143P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21929,820,357 - 29,820,454 (+)MAPPERmRatBN7.2
Rnor_6.01933,494,603 - 33,494,699NCBIRnor6.0
Rnor_5.01944,384,087 - 44,384,183UniSTSRnor5.0
RGSC_v3.41931,737,226 - 31,737,322UniSTSRGSC3.4
Celera1929,311,096 - 29,311,192UniSTS
Cytogenetic Map19q11UniSTS
Cytogenetic Map18q11UniSTS
WI-11812  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21839,531,373 - 39,531,516 (+)MAPPERmRatBN7.2
mRatBN7.21929,819,386 - 29,819,529 (+)MAPPERmRatBN7.2
Rnor_6.01933,493,632 - 33,493,774NCBIRnor6.0
Rnor_6.01840,797,509 - 40,797,651NCBIRnor6.0
Rnor_5.01944,383,116 - 44,383,258UniSTSRnor5.0
Rnor_5.01840,443,600 - 40,443,742UniSTSRnor5.0
RGSC_v3.41841,016,145 - 41,016,287UniSTSRGSC3.4
RGSC_v3.41931,736,255 - 31,736,397UniSTSRGSC3.4
Celera1929,310,125 - 29,310,267UniSTS
Celera1837,781,991 - 37,782,133UniSTS
Cytogenetic Map19q11UniSTS
Cytogenetic Map18q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000064116   ⟹   ENSRNOP00000063471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1841,649,366 - 41,718,218 (+)Ensembl
mRatBN7.2 Ensembl1839,462,773 - 39,531,622 (+)Ensembl
Rnor_6.0 Ensembl1840,732,480 - 40,797,761 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098846   ⟹   ENSRNOP00000087147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1841,649,366 - 41,718,218 (+)Ensembl
mRatBN7.2 Ensembl1839,462,796 - 39,531,310 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104306   ⟹   ENSRNOP00000090711
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1841,649,341 - 41,767,641 (+)Ensembl
mRatBN7.2 Ensembl1839,462,765 - 39,523,031 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104814   ⟹   ENSRNOP00000094412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1841,674,067 - 41,718,525 (+)Ensembl
mRatBN7.2 Ensembl1839,487,465 - 39,531,622 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112095   ⟹   ENSRNOP00000086040
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1841,649,361 - 41,718,525 (+)Ensembl
mRatBN7.2 Ensembl1839,487,339 - 39,531,622 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000139388   ⟹   ENSRNOP00000099768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1841,648,796 - 41,718,525 (+)Ensembl
RefSeq Acc Id: NM_001398640   ⟹   NP_001385569
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81841,649,373 - 41,718,221 (+)NCBI
mRatBN7.21839,462,779 - 39,531,622 (+)NCBI
RefSeq Acc Id: NM_001398641   ⟹   NP_001385570
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81841,649,373 - 41,718,221 (+)NCBI
mRatBN7.21839,462,779 - 39,531,622 (+)NCBI
RefSeq Acc Id: NM_001398642   ⟹   NP_001385571
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81841,649,373 - 41,718,221 (+)NCBI
mRatBN7.21839,462,779 - 39,531,622 (+)NCBI
RefSeq Acc Id: XM_063277281   ⟹   XP_063133351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81841,649,321 - 41,699,424 (+)NCBI
RefSeq Acc Id: XR_005496019
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81841,649,321 - 41,717,675 (+)NCBI
mRatBN7.21839,462,728 - 39,530,990 (+)NCBI
Ensembl Acc Id: ENSRNOP00000063471   ⟸   ENSRNOT00000064116
Ensembl Acc Id: ENSRNOP00000090711   ⟸   ENSRNOT00000104306
Ensembl Acc Id: ENSRNOP00000094412   ⟸   ENSRNOT00000104814
Ensembl Acc Id: ENSRNOP00000087147   ⟸   ENSRNOT00000098846
Ensembl Acc Id: ENSRNOP00000086040   ⟸   ENSRNOT00000112095
RefSeq Acc Id: NP_001385571   ⟸   NM_001398642
- Peptide Label: isoform 3
- UniProtKB: B2RZ62 (UniProtKB/TrEMBL),   A6IWX2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001385570   ⟸   NM_001398641
- Peptide Label: isoform 2
- UniProtKB: G3V9Y9 (UniProtKB/TrEMBL),   A0A8I6A1F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001385569   ⟸   NM_001398640
- Peptide Label: isoform 1
- UniProtKB: A6IWX1 (UniProtKB/TrEMBL),   A0A8I6A1F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133351   ⟸   XM_063277281
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000099768   ⟸   ENSRNOT00000139388
Protein Domains
AP complex mu/sigma subunit

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V9Y9-F1-model_v2 AlphaFold G3V9Y9 1-157 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700770
Promoter ID:EPDNEW_R11293
Type:initiation region
Name:Ap3s1_1
Description:adaptor-related protein complex 3, sigma 1 subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01840,732,493 - 40,732,553EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311115 AgrOrtholog
BioCyc Gene G2FUF-7620 BioCyc
Ensembl Genes ENSRNOG00000003829 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064116 ENTREZGENE
  ENSRNOT00000064116.3 UniProtKB/TrEMBL
  ENSRNOT00000098846 ENTREZGENE
  ENSRNOT00000098846.2 UniProtKB/TrEMBL
  ENSRNOT00000104306.2 UniProtKB/TrEMBL
  ENSRNOT00000104814.2 UniProtKB/TrEMBL
  ENSRNOT00000112095 ENTREZGENE
  ENSRNOT00000112095.2 UniProtKB/TrEMBL
  ENSRNOT00000139388.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.450.60 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8368273 IMAGE-MGC_LOAD
InterPro AP_complex_ssu UniProtKB/TrEMBL
  AP_mu_sigma_su UniProtKB/TrEMBL
  APS3 UniProtKB/TrEMBL
  Clathrin_sm-chain_CS UniProtKB/TrEMBL
  Longin-like UniProtKB/TrEMBL
MGC_CLONE MGC:189303 IMAGE-MGC_LOAD
NCBI Gene 302290 ENTREZGENE
PANTHER PTHR11753 UniProtKB/TrEMBL
Pfam Clat_adaptor_s UniProtKB/TrEMBL
PhenoGen Ap3s1 PhenoGen
PIRSF AP_complex_sigma UniProtKB/TrEMBL
PROSITE CLAT_ADAPTOR_S UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003829 RatGTEx
Superfamily-SCOP Longin_like UniProtKB/TrEMBL
UniProt A0A8I6A1F2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AA56_RAT UniProtKB/TrEMBL
  A0A8I6AKR4_RAT UniProtKB/TrEMBL
  A0ABK0LFZ5_RAT UniProtKB/TrEMBL
  A6IWX1 ENTREZGENE, UniProtKB/TrEMBL
  A6IWX2 ENTREZGENE, UniProtKB/TrEMBL
  B2RZ62 ENTREZGENE, UniProtKB/TrEMBL
  G3V9Y9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-03 Ap3s1  adaptor related protein complex 3 subunit sigma 1  Ap3s1  adaptor-related protein complex 3, sigma 1 subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ap3s1  adaptor-related protein complex 3, sigma 1 subunit   Ap3s1_predicted  adaptor-related protein complex 3, sigma 1 subunit (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ap3s1_predicted  adaptor-related protein complex 3, sigma 1 subunit (predicted)      Symbol and Name status set to approved 70820 APPROVED