Krtap15-1 (keratin associated protein 15-1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Krtap15-1 (keratin associated protein 15-1) Rattus norvegicus
Analyze
Symbol: Krtap15-1
Name: keratin associated protein 15-1
RGD ID: 1311088
Description: Orthologous to human KRTAP15-1 (keratin associated protein 15-1); INTERACTS WITH alpha-Zearalanol; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: keratin associated protein 15; keratin-associated protein 15-1; Krtap15; LOC288297
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81141,616,561 - 41,617,385 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.21128,130,345 - 28,131,169 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1136,816,386 - 36,817,210 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01129,516,458 - 29,517,282 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01128,696,161 - 28,696,985 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01128,780,446 - 28,781,270 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1128,780,446 - 28,781,270 (+)Ensemblrn6Rnor6.0
Rnor_5.01132,399,617 - 32,400,441 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41128,652,675 - 28,653,499 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1127,845,791 - 27,846,615 (+)NCBICelera
RGSC_v3.11128,652,713 - 28,653,166 (+)NCBI
Cytogenetic Map11q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Comprehensive gene review and curation RGD comprehensive gene curation

Genomics

Comparative Map Data
Krtap15-1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81141,616,561 - 41,617,385 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.21128,130,345 - 28,131,169 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1136,816,386 - 36,817,210 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01129,516,458 - 29,517,282 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01128,696,161 - 28,696,985 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01128,780,446 - 28,781,270 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1128,780,446 - 28,781,270 (+)Ensemblrn6Rnor6.0
Rnor_5.01132,399,617 - 32,400,441 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41128,652,675 - 28,653,499 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1127,845,791 - 27,846,615 (+)NCBICelera
RGSC_v3.11128,652,713 - 28,653,166 (+)NCBI
Cytogenetic Map11q11NCBI
KRTAP15-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382130,440,275 - 30,440,869 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2130,440,275 - 30,440,869 (+)Ensemblhg38GRCh38
GRCh372131,812,593 - 31,813,187 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362130,734,517 - 30,734,969 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342130,734,516 - 30,734,969NCBI
Celera2116,995,793 - 16,996,245 (+)NCBICelera
Cytogenetic Map21q22.11NCBI
HuRef2117,221,592 - 17,222,044 (+)NCBIHuRef
CHM1_12131,374,351 - 31,374,803 (+)NCBICHM1_1
T2T-CHM13v2.02128,806,157 - 28,806,751 (+)NCBIT2T-CHM13v2.0
Krtap15-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391688,625,897 - 88,626,732 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1688,617,103 - 88,626,732 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381688,829,009 - 88,829,844 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1688,820,215 - 88,829,844 (+)Ensemblmm10GRCm38
MGSCv371688,829,254 - 88,830,089 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361688,717,868 - 88,718,703 (+)NCBIMGSCv36mm8
Celera1689,032,251 - 89,033,086 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1651.41NCBI
LOC112438081
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22226,587,203 - 26,587,786 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12121,442,854 - 21,443,420 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02116,836,813 - 16,837,379 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12130,221,442 - 30,221,855 (+)NCBIPanPan1.1PanPan1.1panPan2
KRTAP13-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13125,235,710 - 25,236,472 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3125,227,072 - 25,227,562 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
LOC120890445
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497125,783,650 - 25,784,469 (+)NCBIHiC_Itri_2
KRTAP15-1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660714,329,856 - 4,330,572 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Krtap15-1
4 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:53
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000072546
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11381815448818154Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat


Expression

RNA-SEQ Expression

appendage
ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 5 4 2 1 1 1 22 1 4 17 19 1

Sequence


Ensembl Acc Id: ENSRNOT00000072546   ⟹   ENSRNOP00000067144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1128,780,446 - 28,781,270 (+)Ensembl
RefSeq Acc Id: NM_001105896   ⟹   NP_001099366
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81141,616,561 - 41,617,385 (+)NCBI
mRatBN7.21128,130,345 - 28,131,169 (+)NCBI
Rnor_6.01128,780,446 - 28,781,270 (+)NCBI
Rnor_5.01132,399,617 - 32,400,441 (+)NCBI
RGSC_v3.41128,652,675 - 28,653,499 (+)RGD
Celera1127,845,791 - 27,846,615 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099366 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM10668 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001099366   ⟸   NM_001105896
- UniProtKB: A6JLA3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067144   ⟸   ENSRNOT00000072546

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RC38-F1-model_v2 AlphaFold M0RC38 1-150 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698034
Promoter ID:EPDNEW_R8558
Type:single initiation site
Name:Krtap15-1_1
Description:keratin associated protein 15-1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01128,780,432 - 28,780,492EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311088 AgrOrtholog
BioCyc Gene G2FUF-22010 BioCyc
Ensembl Genes ENSRNOG00000049399 Ensembl
InterPro KRTAP_PMG UniProtKB/TrEMBL
KEGG Report rno:288297 UniProtKB/TrEMBL
NCBI Gene 288297 ENTREZGENE
Pfam PMG UniProtKB/TrEMBL
PhenoGen Krtap15-1 PhenoGen
RatGTEx ENSRNOG00000049399 RatGTEx
UniProt A6JLA3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-09 Krtap15-1  keratin associated protein 15-1  Krtap15  keratin associated protein 15   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Krtap15  keratin associated protein 15   Krtap15_predicted  keratin associated protein 15 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Krtap15_predicted  keratin associated protein 15 (predicted)  Krtap15-1_predicted  keratin associated protein 15-1 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Krtap15-1_predicted  keratin associated protein 15-1 (predicted)      Symbol and Name status set to approved 70820 APPROVED