Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ZFYVE21 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Zfyve21 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ZFYVE21 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | ISO | Zfyve21 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ZFYVE21 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ZFYVE21 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of ZFYVE21 mRNA | CTD | PMID:17555576 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ZFYVE21 mRNA | CTD | PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ZFYVE21 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Zfyve21 (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of ZFYVE21 mRNA | CTD | PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZFYVE21 mRNA | CTD | PMID:21570461 | 2,4,6-trinitrotoluene | affects expression | EXP | | 6480464 | Trinitrotoluene affects the expression of ZFYVE21 mRNA | CTD | PMID:21346803 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of ZFYVE21 mRNA | CTD | PMID:21346803 | 2-methylcholine | affects expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of ZFYVE21 mRNA | CTD | PMID:21179406 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ZFYVE21 mRNA | CTD | PMID:30047161 | aflatoxin B1 | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of ZFYVE21 mRNA | CTD | PMID:19770486 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of ZFYVE21 mRNA | CTD | PMID:30047161 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of ZFYVE21 mRNA | CTD | PMID:30779732 | antirheumatic drug | increases expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of ZFYVE21 mRNA | CTD | PMID:24449571 | benzo[a]pyrene | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ZFYVE21 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases methylation | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ZFYVE21 promoter | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | ZFYVE21 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of ZFYVE21 intron | CTD | PMID:30157460 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ZFYVE21 mRNA | CTD | PMID:25181051 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of ZFYVE21 gene | CTD | PMID:28505145 | bisphenol A | decreases methylation | ISO | Zfyve21 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of ZFYVE21 promoter | CTD | PMID:27312807 | carbon nanotube | affects expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Nanotubes and Carbon affects the expression of ZFYVE21 mRNA | CTD | PMID:25554681 | carbon nanotube | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of ZFYVE21 mRNA | CTD | PMID:25554681 | chlordecone | increases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Chlordecone results in increased expression of ZFYVE21 mRNA | CTD | PMID:33711761 | chlorpyrifos | increases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of ZFYVE21 mRNA | CTD | PMID:37019170 | copper(II) sulfate | decreases expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ZFYVE21 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ZFYVE21 mRNA | CTD | PMID:25562108 and PMID:27989131 | dibutyl phthalate | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of ZFYVE21 mRNA | CTD | PMID:21266533 | doxorubicin | increases expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of ZFYVE21 mRNA | CTD | PMID:29803840 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of ZFYVE21 mRNA | CTD | PMID:29391264 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of ZFYVE21 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Zfyve21 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ZFYVE21 mRNA | CTD | PMID:22206623 | folic acid | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of ZFYVE21 mRNA | CTD | PMID:25629700 | FR900359 | decreases phosphorylation | ISO | ZFYVE21 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of ZFYVE21 protein | CTD | PMID:37730182 | inulin | multiple interactions | ISO | Zfyve21 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ZFYVE21 mRNA | CTD | PMID:36331819 | leflunomide | decreases expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of ZFYVE21 mRNA | CTD | PMID:28988120 | menadione | affects expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of ZFYVE21 mRNA | CTD | PMID:20044591 | methapyrilene | increases methylation | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of ZFYVE21 intron | CTD | PMID:30157460 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of ZFYVE21 mRNA | CTD | PMID:30467583 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of ZFYVE21 mRNA | CTD | PMID:30047161 | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | multiple interactions | ISO | Zfyve21 (Mus musculus) | 6480464 | [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ZFYVE21 mRNA | CTD | PMID:25566086 | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of ZFYVE21 mRNA | CTD | PMID:24136188 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ZFYVE21 mRNA | CTD | PMID:25729387 | paracetamol | affects expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ZFYVE21 mRNA | CTD | PMID:17562736 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Zfyve21 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ZFYVE21 mRNA more ... | CTD | PMID:36331819 | pirinixic acid | multiple interactions | ISO | Zfyve21 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ZFYVE21 mRNA | CTD | PMID:19710929 | potassium dichromate | increases expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of ZFYVE21 protein | CTD | PMID:23718831 | propiconazole | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | propiconazole results in decreased expression of ZFYVE21 mRNA | CTD | PMID:21278054 | silicon dioxide | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of ZFYVE21 mRNA | CTD | PMID:19073995 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of ZFYVE21 mRNA | CTD | PMID:19281266 | succimer | multiple interactions | ISO | Zfyve21 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ZFYVE21 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ZFYVE21 mRNA | CTD | PMID:21641980 and PMID:26378955 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of ZFYVE21 mRNA | CTD | PMID:30047161 | tamoxifen | affects expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Tamoxifen affects the expression of ZFYVE21 mRNA | CTD | PMID:17555576 | temozolomide | increases expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of ZFYVE21 mRNA | CTD | PMID:31758290 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of ZFYVE21 mRNA | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of ZFYVE21 mRNA | CTD | PMID:31919559 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ZFYVE21 mRNA] | CTD | PMID:31150632 | tetraphene | increases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of ZFYVE21 mRNA | CTD | PMID:26377693 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of ZFYVE21 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of ZFYVE21 mRNA | CTD | PMID:23557971 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ZFYVE21 mRNA | CTD | PMID:25729387 | tungsten | increases expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Tungsten results in increased expression of ZFYVE21 mRNA | CTD | PMID:30912803 | tunicamycin | decreases expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of ZFYVE21 mRNA | CTD | PMID:29453283 | valproic acid | affects expression | ISO | Zfyve21 (Mus musculus) | 6480464 | Valproic Acid affects the expression of ZFYVE21 mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | ISO | ZFYVE21 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ZFYVE21 mRNA | CTD | PMID:29154799 | |