Advanced Search (OLGA)

Gene: Robo3 (roundabout guidance receptor 3) Rattus norvegicus

Analyze

Symbol:

Robo3

Name:

roundabout guidance receptor 3

RGD ID:

1311018

Description:

Involved in positive regulation of axon guidance. Predicted to be located in axon. Orthologous to human ROBO3 (roundabout guidance receptor 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC315564; roundabout homolog 3; roundabout homolog 3 (Drosophila); roundabout, axon guidance receptor, homolog 3; roundabout, axon guidance receptor, homolog 3 (Drosophila)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ROBO3 (roundabout guidance receptor 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Robo3 (roundabout guidance receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Robo3 (roundabout guidance receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ROBO3 (roundabout guidance receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ROBO3 (roundabout guidance receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Robo3 (roundabout guidance receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ROBO3 (roundabout guidance receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ROBO3 (roundabout guidance receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Robo3 (roundabout guidance receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Robo3 (roundabout guidance receptor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	KAZALD1 (Kazal type serine peptidase inhibitor domain 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ROBO3 (roundabout guidance receptor 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Robo3 (roundabout guidance receptor 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	robo3 (roundabout, axon guidance receptor, homolog 3 (Drosophila))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PhylomeDB)
Danio rerio (zebrafish):	zgc:77784	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	sax-3	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	robo1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	robo1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	robo2	Alliance	DIOPT (Hieranoid\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	robo3	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector)
Drosophila melanogaster (fruit fly):	robo3	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	robo3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	robo3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	45,322,323 - 45,340,466 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	45,323,344 - 45,340,222 (-)	Ensembl				GRCr8
mRatBN7.2	8	37,133,542 - 37,151,674 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	37,133,916 - 37,151,315 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	41,150,815 - 41,167,744 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	39,433,875 - 39,450,802 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	37,296,780 - 37,313,715 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	8	45,390,445 - 45,407,384 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	8	47,560,807 - 47,577,743 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	8	46,103,376 - 46,120,315 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	8	37,434,815 - 37,451,738 (-)	NCBI		F344_StmMcwi
Rnor_6.0	8	39,892,792 - 39,923,735 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	39,892,792 - 39,907,478 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	39,893,678 - 39,911,529 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	38,668,913 - 38,683,439 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	37,304,456 - 37,318,986 (+)	NCBI		Celera
RGSC_v3.1	8	38,679,386 - 38,715,966 (-)	NCBI
Cytogenetic Map	8	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Brain Injuries (IEP)

conjugate gaze palsy (ISO)

Familial Horizontal Gaze Palsy with Progressive Scoliosis (ISO)

Familial Horizontal Gaze Palsy with Progressive Scoliosis, 1 (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP,ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Bufotalin (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cytarabine (ISO)

diiodine (ISO)

diquat (ISO)

dorsomorphin (ISO)

etoposide (ISO)

folic acid (ISO)

GSK-J4 (ISO)

ivermectin (ISO)

mercury dibromide (ISO)

methylmercury chloride (EXP,ISO)

Moniliformin (ISO)

N-methyl-4-phenylpyridinium (ISO)

phenylmercury acetate (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

potassium bromate (ISO)

resveratrol (ISO)

SB 431542 (ISO)

scopolamine (EXP)

sodium arsenite (ISO)

testosterone (EXP)

titanium dioxide (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

valproic acid (EXP)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon guidance (ISO)

axon midline choice point recognition (IEA,ISO)

cell differentiation (IEA)

chemotaxis (IEA)

commissural neuron axon guidance (IEA,ISO)

nervous system development (IEA)

neuron migration (ISO)

positive regulation of axon guidance (IMP)

Cellular Component

axon (IEA,ISO)

membrane (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Robo3.1A suppresses slit-mediated repulsion by triggering degradation of Robo2.	Li L, etal., J Neurosci Res. 2014 Jul;92(7):835-46. doi: 10.1002/jnr.23364.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Expression of netrin-1, slit-1 and slit-3 but not of slit-2 after cerebellar and spinal cord lesions.	Wehrle R, etal., Eur J Neurosci. 2005 Nov;22(9):2134-44.

Additional References at PubMed

PMID:15084255	PMID:15233918	PMID:18466743	PMID:18986510	PMID:19747951	PMID:19906978	PMID:30843071

Genomics

Comparative Map Data

Robo3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	45,322,323 - 45,340,466 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	45,323,344 - 45,340,222 (-)	Ensembl				GRCr8
mRatBN7.2	8	37,133,542 - 37,151,674 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	37,133,916 - 37,151,315 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	41,150,815 - 41,167,744 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	39,433,875 - 39,450,802 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	37,296,780 - 37,313,715 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	8	45,390,445 - 45,407,384 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	8	47,560,807 - 47,577,743 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	8	46,103,376 - 46,120,315 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	8	37,434,815 - 37,451,738 (-)	NCBI		F344_StmMcwi
Rnor_6.0	8	39,892,792 - 39,923,735 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	39,892,792 - 39,907,478 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	39,893,678 - 39,911,529 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	38,668,913 - 38,683,439 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	37,304,456 - 37,318,986 (+)	NCBI		Celera
RGSC_v3.1	8	38,679,386 - 38,715,966 (-)	NCBI
Cytogenetic Map	8	q22	NCBI

ROBO3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	124,865,432 - 124,881,471 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	124,865,432 - 124,881,471 (+)	Ensembl			hg38	GRCh38
GRCh37	11	124,735,328 - 124,751,367 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	124,240,492 - 124,256,572 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	11	121,895,484 - 121,911,549 (+)	NCBI		Celera
Cytogenetic Map	11	q24.2	NCBI
HuRef	11	120,677,663 - 120,693,728 (+)	NCBI		HuRef
CHM1_1	11	124,621,414 - 124,637,480 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	124,894,054 - 124,910,095 (+)	NCBI		T2T-CHM13v2.0

Robo3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	37,327,341 - 37,344,730 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	37,326,965 - 37,344,542 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	37,416,045 - 37,433,436 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	37,415,669 - 37,433,246 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	37,223,630 - 37,240,760 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	37,165,835 - 37,179,805 (-)	NCBI		MGSCv36	mm8
Celera	9	34,630,435 - 34,647,581 (-)	NCBI		Celera
Cytogenetic Map	9	A4	NCBI
cM Map	9	20.76	NCBI

Robo3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	25,937,624 - 25,953,189 (+)	Ensembl
ChiLan1.0	NW_004955412	25,937,624 - 25,953,458 (+)	NCBI	ChiLan1.0	ChiLan1.0

ROBO3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	125,560,773 - 125,576,739 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	126,665,737 - 126,681,637 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	119,692,232 - 119,708,309 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	123,607,268 - 123,623,356 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	123,607,268 - 123,623,356 (+)	Ensembl			panPan2	panpan1.1

ROBO3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	9,563,353 - 9,579,111 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	9,563,345 - 9,579,289 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	9,608,853 - 9,613,840 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	9,503,132 - 9,508,122 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	5	9,575,801 - 9,580,788 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	9,546,252 - 9,551,241 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	9,582,695 - 9,587,687 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Robo3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	107,057,543 - 107,074,263 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936743	1,305,341 - 1,320,702 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936743	1,305,108 - 1,321,819 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ROBO3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	52,065,499 - 52,081,625 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	52,065,043 - 52,081,764 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	57,580,550 - 57,597,135 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ROBO3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	116,004,129 - 116,024,691 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	116,008,742 - 116,024,474 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666043	10,093,762 - 10,106,598 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Robo3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624927	872,197 - 887,079 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624927	872,197 - 887,316 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Robo3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	33,597,691 - 33,614,297 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Robo3
82 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	583
Count of miRNA genes:	243
Interacting mature miRNAs:	280
Transcripts:	ENSRNOT00000064141
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39752803	84752803	Rat
1357398	Slep3	Serum leptin concentration QTL 3	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	17994105	50763951	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	39106258	91341052	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	16994642	61994642	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	39106258	91341052	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	39106363	103375781	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	15952279	60952279	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	12964165	57964165	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	39106258	84106258	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	12964165	57964165	Rat
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	10382540	55382540	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	39106363	103375781	Rat
61464	Niddm11	Non-insulin dependent diabetes mellitus QTL 11	3.1	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	44477926	89477926	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	16994642	61994642	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	10382540	55382540	Rat
61337	Bp22	Blood pressure QTL 22	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	51589833	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	39106258	103375958	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	12964165	57964165	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	10382540	55382540	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	39106258	91341052	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	35464071	107982864	Rat
2302278	Gluco36	Glucose level QTL 36	4.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	37760859	58991895	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	10382540	55382540	Rat
724514	Uae15	Urinary albumin excretion QTL 15	2.9		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	37760859	61459705	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	35464071	71842899	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	39106258	84106258	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	31543661	76543661	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	84106258	Rat
61358	Bp39	Blood pressure QTL 39	2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	44447837	89447837	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	35464071	107982864	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	17993862	62252873	Rat
1331744	Bp217	Blood pressure QTL 217	3.398		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	67378345	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	39106258	91341052	Rat
724540	Uae8	Urinary albumin excretion QTL 8	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	8	39106258	103375958	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	35464071	107982864	Rat
1359021	Bp271	Blood pressure QTL 271	1.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	34125902	55607752	Rat
2302367	Slep5	Serum leptin concentration QTL 5	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	17994105	50763951	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	44475043	89475043	Rat
70206	Alc20	Alcohol consumption QTL 20	2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	8	39106258	49610361	Rat

Markers in Region

D8Cebr1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	37,146,536 - 37,146,695 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	39,905,409 - 39,905,567	NCBI	Rnor6.0
Rnor_5.0	8	39,906,295 - 39,906,453	UniSTS	Rnor5.0
RGSC_v3.4	8	38,681,530 - 38,681,688	UniSTS	RGSC3.4
Celera	8	37,306,209 - 37,306,369	UniSTS
Cytogenetic Map	8	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
12	8	42	138	53	53	22	38	22	6	223	106	7	123	77	79	31	15	15

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001394075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595621	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265428	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000064141 ⟹ ENSRNOP00000060623

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	37,133,916 - 37,148,446 (-)	Ensembl
Rnor_6.0 Ensembl	8	39,892,792 - 39,907,478 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118811 ⟹ ENSRNOP00000094407

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	45,323,344 - 45,340,222 (-)	Ensembl
mRatBN7.2 Ensembl	8	37,133,916 - 37,151,315 (-)	Ensembl

RefSeq Acc Id:

NM_001394075 ⟹ NP_001381004

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	45,323,344 - 45,340,222 (-)	NCBI
mRatBN7.2	8	37,134,563 - 37,151,448 (-)	NCBI
Dahl_SR_JrHsd	8	45,390,445 - 45,407,384 (-)	NCBI
Lyon_Normotensive	8	47,560,807 - 47,577,743 (-)	NCBI
Lyon_Hypertensive	8	46,103,376 - 46,120,315 (-)	NCBI
F344_StmMcwi	8	37,434,815 - 37,451,738 (-)	NCBI

RefSeq Acc Id:

XM_017595621 ⟹ XP_017451110

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	45,323,645 - 45,340,466 (-)	NCBI
mRatBN7.2	8	37,134,854 - 37,151,665 (-)	NCBI
Rnor_6.0	8	39,893,439 - 39,923,735 (-)	NCBI

Sequence:

show sequence

ACGGGTGGTGAAATAGCATTCAGAGGTTGCTCCTAGGAAATGCTGAATATGTATGAACTATGCA
ATCAGGACCGAGGAGCTCCCAGGGGACTCTGGCACTGGAGGGTGGAGAGAAGAACCAGCGAAGG
AGGACAGCCCGCGCAGAGGCACGGCCGTACCCAGGCACGCCTGCAGGACAGCGGCATCGTGGCT
GCGGCAGCGCGCAAAGGCTGTGGAGGGGCTTACGGCTCCCGGCCCACGGGTTCCAGACCCAGGG
GCTGGGCTCCGAGGCCCCCACCCAAGACCCAGGCAGGCCGCATTATGCTGCGCTACCTGCTTAA
AACACTACTACAGATGAACTTGTTCGCGGACTCCCTGGCGGGAGACATCACCAACTCCAGCGAG
CTACTCTTCGGTTTCAACTCCTCGCTGGCAGCGCTCAACCCTAGCCTGCTTCCTCCTGGAGACC
CCTCTCTCAATGGGTCAAGAGTTGGACCCGAGGATGCCATGCCACGCATCGTGGAGCAGCCGCC
AGATCTGCTCGTTTCCAGGGGCGAGCCGGCCACTCTGCCCTGCCGTGCTGAAGGCCGGCCTCGA
CCCAACATCGAGTGGTACAAGAATGGGGCGCGCGTGGCCACTGCACGCGAGGATCCGCGGGCTC
ACCGCCTGCTGCTGCCCAGCGGCGCCCTCTTCTTTCCCCGCATCGTGCACGGGCGTCGCTCTCG
GCCTGACGAGGGTGTCTACACCTGTGTGGCTCGCAACTACCTGGGAGCAGCGGCTAGCAGAAAC
GCCTCTCTGGAAGTAGCTGTCCTCCGAGACGATTTCCGGCAATCTCCTGGGAACGTGGTGGTAG
CAGTGGGGGAGCCAGCAGTAATGGAATGCGTGCCCCCTAAGGGTCACCCAGAGCCTTTGGTGAC
CTGGAAGAAGGGCAATACAAAGCTTAAGGAAGAGGAGGGAAGGATCACCATACGTGGAGGAAAG
CTGATGATGTCACATACATTCAAGAGTGATGCTGGCATGTACATGTGTGTAGCCTCCAACATGG
CTGGAGAACGAGAGAGTGGGGCAGCTGAACTTGTGGTACTGGAGCGTCCCTCATTTCTGCGTAG
ACCAATAAACCAGGTTGTCCTGGCTGATGCCCCTGTGAATTTCCTGTGTGAGGTGCAGGGAGAT
CCCCAGCCCAATCTACGCTGGCGCAAGGATGATGGGGAGCTGCCCACTGGCAGGTATGAGATTC
GGAGTGACCACAGCCTTTGGATCGAGCAAGTGAGTGCTGAAGACGAGGGGACTTACACCTGTGT
GGCAGAAAACAGTGTGGGCCGAGCAGAGGCATCTGGCTCCCTCAGTGTTCACGTCCCACCACAG
TTTGTGACTAAGCCCCAGAACCAGACAGCAGCTCCTGGAGAAAACGTGTCTTTCCAATGTGAGA
CCAAAGGAAACCCACCACCTGCCATCTTCTGGCAGAAGGAAGGGAGTCAAGTCTTGCTTTTCCC
TAGTCAGTCACTCCAGCCCATGGGACGCCTCTTAGTCTCTCCAAGAGGCCAGCTCAACATCACT
GAAGTAAAGATCGGGGATGGTGGCTACTATGTGTGCCAGGCTGTCAGTGTGGCTGGTAGCATCC
TGGCTAAGGCCCTGTTAGAGATAAAAGGAGCCTCCATAGATGGACTACCTCCCATCATTCTCCA
GGGACCAGCCAATCAGACATTGGTACTTGGCTCTTCTGTGTGGCTGCCATGCAGAGTGATTGGA
AACCCTCAGCCCAATGTCCAATGGAAGAAGGATGAGACGTGGCTGCAGGGGGATAACTCACAGT
TCAACTTAATGGACAACGGCACACTATACATTGCCAGTGTACAGGAGATGGACATGGGTTTCTA
CAGCTGTGTGGCCAAGAGTTCCATAGGGGAGGCCACATGGAATAGCTGGCTTAGGAAGCGAGAA
CATTGGGGAGCATCACCAGGTCCAGCAACAGAACCCGGTAATCCTCCAGGCCCTCCCTCTCAGC
CAATAGTCACAGAGGTAACCACAAACAGCATTACCTTGACCTGGAAGCCCAATCCACAGTCTGG
GGCCAGAGCTACCTCCTATGTGATAGAGGCCTTCAGCCAAGCAGCTGGCAACACGTGGCGGACG
GTGGCAGATGGGGTACAGCTGGAAACGCACACCGTCAGCGGCCTGCAGCCCAATACCATCTACC
TATTCCTCGTGAGAGCTGTTGGAGCCTGGGGCCTCAGTGAACCCAGTCCTGTCTCTGAGCCTGT
TCAAACCCAGGACAGCAGCCTATCTAGGCCAGTGGAGGACCCGTGGAAAGGCCAGCAAGGACTG
GCTGAAGTGGCCGTGCGAATGCAGGAGCCCATAGTCCTTGGACCCAGAACTCTGCAGGTGTCCT
GGACTGTAGAGGGCCCTGGCCAGCTGGTTCAGGGATTCCGTGTGTCTTGGAGGATTGCAGGCCT
TGACCAGGGAAGCTGGACAGCGCTAGACGTACAGAGTCCACACAAGCAAAGTACTGTGCTAAGA
GGCCTCCCCCCAGGGTCCCAAATACAGATCAAGGTGCAAGTCCAAGGCCAGGAGGGGCTGGGGG
CTGAAAGCCCCTCTGTGACCCGGAGCATTCCTGAAGAGGCCCCCAGTGGCCCCCCTCAGGGAGT
GGCTGTGGCCTTGGGGGGTGATCGCAACAGCAGTATCACTGTATCCTGGGAGCCTCCACTTCCC
TCCCAGCAAAATGGGGTTATCACTGAATACCAGATCTGGTGCCTGGGTAATGAAAGCCGATTCC
ACCTCAATCGATCTGCAGCAGGCTGGGCACGCTCTGTGATGTTCCGGGGACTGCTACCGGGCCT
GCTCTATAGAGCCATAGTGGCAGCAGCTACCAGCGCTGGCGTGGGCGTGGCCAGTGCCCCAGTG
CTAGTGCAGCTGCCATTCCCTCCGGTTGCGGAGCCCGGGCCTGAGGTCAGCGAGGGGCTGGCGG
AACGGTTGTCTAGGGTGCTGCGGAAGCCTGCTTTCCTGGCTGGCAGCAGCGCGGCCTGTGGGGC
GCTGCTTCTCGGGCTCTGCGCCGCCCTCTATCGGCGCCAGAAGCAACGCAAAGAGCTCAGTCAT
TATACCGCCTCCTTTGCCTACACACCTGCAGTGTCCTTTCCACACTCAGAGGGCCTTTCTGGAT
CCAGTTCCAGGCCACCCATGGGCCTTGGCCCTGCTGCCTACCCATGGCTGGCAGACTCCTGGCC
CCACCCATCTCGAAGTCCCTCAGCTCAGGAACCCCGGGGGAGCTGCTGCCCCAGCAATCCTGAT
CCAGATGATAGATACTACAATGAGGCAGGAATCTCCCTGTACTTGGCTCAGACTGCACGGGGTG
CTAATGCCCCTGGCGAGGGTCCTGTCTACAGCACCATTGACCCAGTAGGGGAAGAGCTACAGAC
CTTCCACGGAGGGTTCCCTCAACATTCTTCTGGGGACCCAAGCACCTGGAGCCAGTATGCTCCC
CCCGAATGGAGCGAGGGGGACAGTGGAGCCAGGGGAGGCAAAGGGAAGCTTCTAGGCAAACCTG
TGCAGATGCCCTCTTTGAGCTGGCCAGAAGCCCTGCCGCCACCTCCCCCTTCCTGTGAATTGAG
CTGCCCAGAGGGGCCTGAGGAGGAGCTGAAGGGCAGTTCAGATCTGGAAGAGTGGTGCCCACCA
ATGCCTGAGAAAAAACACTTGATTGACTCACGTTCCAGTGGTGCGTGCATGGTGGCTCCAGCCC
GAGGGGAAACTCCCTCCCCTACCTCTTCTTACGGACAGCAGTCCACAGCCACTCTTACCCCCTC
ACCTCCTGACCCTCCCCAGCCCCCTAGCGACATCCCACATCTCCATCAGATGCCCAGGAGGGTG
CCCCTTGGACCAAGTTCTCCTCTCAGCGTATCCCAGCCTGCTCTGAGTAGCCATGATGGAAGGC
CTGTTGGCCTGGGTGCTGGCCCTATAGTCTCTTATCACCCTAGCCCCAGTCCTGTCCCTAGTAC
AGCCAGCAGTGCACCAGGGAGAACTCGCCAGGTAACTGGAGAGATGACTCCCCCACTCCATGGA
CACCGTGCCCGAATCCGGAAGAAAACCAAGGCTCTTCCACATAGAAGGGAACACAGTCCTGGGG
ACTTGCCCCCACCACCCTTGCCACCACCAGAGGAAGAGACGAGCTGGCCCTTGGGTCTGAGAGC
AGCAGGCAGCATGTCTTCCCTAGAGCGAGAGCACAGTGGGGAGAGGAGAGTGGCCCAGGCAGTG
CCTCTAGGGGCCCAACCTCCAGGGGCCCAACGTGGCCCCCACCCTGATGCTGCACTTCTGGGTT
GTGCTGCAGAAGAGGCCTGGCTTCCATACGGCAGACCAAGCTTCCTGAGCCATGGCCAGGGCAC
CAGCACCTGCTCTACCGCTGGTAGCAATTCTTCTAGGGGTTCCAACAGCTCTCGAGGTTCTCGG
GGCTCTCGGGGCCCTGGACGCAGCCGAAGCCGGAGCCAGAGTCAGAGCCAGAGGCCGGGACGGA
ATCGCCGACAGGAACCAAGATGACCCTTCCTGAAGCAACGAGCATATTGAAAGTGCCACAGGGC
AAGAATGGGGACCCCTTCCCTGGTCAGCATACATGAGTCACGAGGAGCAAGGATGGACCACCTT
TCCTCCCGGCAGTGATGCTCGTGACTCACTGAAGCACAAGGTCTCAACAGTTCTAGTTGCTATG
GGAACCGGAGGAGCAGCTCTTCCCTTTCCATCCCTTTATGACTGAGACATGTCTGTACAAAAGG
AGAAAAGAAAAAGCCTCTGCTCTGA

hide sequence

RefSeq Acc Id:

XM_063265426 ⟹ XP_063121496

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	45,322,323 - 45,340,465 (-)	NCBI

RefSeq Acc Id:

XM_063265427 ⟹ XP_063121497

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	45,323,655 - 45,335,130 (-)	NCBI

RefSeq Acc Id:

XM_063265428 ⟹ XP_063121498

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	45,323,655 - 45,331,987 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001381004	(Get FASTA)	NCBI Sequence Viewer
	XP_017451110	(Get FASTA)	NCBI Sequence Viewer
	XP_063121496	(Get FASTA)	NCBI Sequence Viewer
	XP_063121497	(Get FASTA)	NCBI Sequence Viewer
	XP_063121498	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL84064	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000094407
	ENSRNOP00000094407.1

RefSeq Acc Id:	XP_017451110 ⟸ XM_017595621
- Peptide Label:	isoform X2
- UniProtKB:	A6KRL2 (UniProtKB/TrEMBL), D3ZKA2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLNMYELCNQDRGAPRGLWHWRVERRTSEGGQPAQRHGRTQARLQDSGIVAAAARKGCGGAYGS RPTGSRPRGWAPRPPPKTQAGRIMLRYLLKTLLQMNLFADSLAGDITNSSELLFGFNSSLAALN PSLLPPGDPSLNGSRVGPEDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVA TAREDPRAHRLLLPSGALFFPRIVHGRRSRPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFR QSPGNVVVAVGEPAVMECVPPKGHPEPLVTWKKGNTKLKEEEGRITIRGGKLMMSHTFKSDAGM YMCVASNMAGERESGAAELVVLERPSFLRRPINQVVLADAPVNFLCEVQGDPQPNLRWRKDDGE LPTGRYEIRSDHSLWIEQVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQFVTKPQNQTAAPG ENVSFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPMGRLLVSPRGQLNITEVKIGDGGYYVCQ AVSVAGSILAKALLEIKGASIDGLPPIILQGPANQTLVLGSSVWLPCRVIGNPQPNVQWKKDET WLQGDNSQFNLMDNGTLYIASVQEMDMGFYSCVAKSSIGEATWNSWLRKREHWGASPGPATEPG NPPGPPSQPIVTEVTTNSITLTWKPNPQSGARATSYVIEAFSQAAGNTWRTVADGVQLETHTVS GLQPNTIYLFLVRAVGAWGLSEPSPVSEPVQTQDSSLSRPVEDPWKGQQGLAEVAVRMQEPIVL GPRTLQVSWTVEGPGQLVQGFRVSWRIAGLDQGSWTALDVQSPHKQSTVLRGLPPGSQIQIKVQ VQGQEGLGAESPSVTRSIPEEAPSGPPQGVAVALGGDRNSSITVSWEPPLPSQQNGVITEYQIW CLGNESRFHLNRSAAGWARSVMFRGLLPGLLYRAIVAAATSAGVGVASAPVLVQLPFPPVAEPG PEVSEGLAERLSRVLRKPAFLAGSSAACGALLLGLCAALYRRQKQRKELSHYTASFAYTPAVSF PHSEGLSGSSSRPPMGLGPAAYPWLADSWPHPSRSPSAQEPRGSCCPSNPDPDDRYYNEAGISL YLAQTARGANAPGEGPVYSTIDPVGEELQTFHGGFPQHSSGDPSTWSQYAPPEWSEGDSGARGG KGKLLGKPVQMPSLSWPEALPPPPPSCELSCPEGPEEELKGSSDLEEWCPPMPEKKHLIDSRSS GACMVAPARGETPSPTSSYGQQSTATLTPSPPDPPQPPSDIPHLHQMPRRVPLGPSSPLSVSQP ALSSHDGRPVGLGAGPIVSYHPSPSPVPSTASSAPGRTRQVTGEMTPPLHGHRARIRKKTKALP HRREHSPGDLPPPPLPPPEEETSWPLGLRAAGSMSSLEREHSGERRVAQAVPLGAQPPGAQRGP HPDAALLGCAAEEAWLPYGRPSFLSHGQGTSTCSTAGSNSSRGSNSSRGSRGSRGPGRSRSRSQ SQSQRPGRNRRQEPR hide sequence

Ensembl Acc Id:

ENSRNOP00000060623 ⟸ ENSRNOT00000064141

Ensembl Acc Id:

ENSRNOP00000094407 ⟸ ENSRNOT00000118811

RefSeq Acc Id:	NP_001381004 ⟸ NM_001394075
- UniProtKB:	A0A8I6AJI9 (UniProtKB/TrEMBL), A6KRL2 (UniProtKB/TrEMBL), D3ZKA2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121496 ⟸ XM_063265426
- Peptide Label:	isoform X1
- UniProtKB:	A6KRL2 (UniProtKB/TrEMBL), D3ZKA2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063121497 ⟸ XM_063265427
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063121498 ⟸ XM_063265428
- Peptide Label:	isoform X4

Protein Domains

Fibronectin type-III Ig-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZKA2-F1-model_v2	AlphaFold	D3ZKA2	1-1305	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311018	AgrOrtholog
BioCyc Gene	G2FUF-31085	BioCyc
Ensembl Genes	ENSRNOG00000030016	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000118811	ENTREZGENE
	ENSRNOT00000118811.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	FN3_sf	UniProtKB/TrEMBL
	FN_III	UniProtKB/TrEMBL
	Ig-like	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/TrEMBL
	Neural/epithelial_adhesion	UniProtKB/TrEMBL
NCBI Gene	315564	ENTREZGENE
PANTHER	CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN	UniProtKB/TrEMBL
	ROUNDABOUT HOMOLOG 3	UniProtKB/TrEMBL
Pfam	fn3	UniProtKB/TrEMBL
	I-set	UniProtKB/TrEMBL
	Ig_3	UniProtKB/TrEMBL
PhenoGen	Robo3	PhenoGen
PROSITE	FN3	UniProtKB/TrEMBL
	IG_LIKE	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000030016	RatGTEx
SMART	FN3	UniProtKB/TrEMBL
	IGc2	UniProtKB/TrEMBL
	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	FN_III-like	UniProtKB/TrEMBL
	SSF48726	UniProtKB/TrEMBL
UniProt	A0A8I6AJI9	ENTREZGENE, UniProtKB/TrEMBL
	A6KRL2	ENTREZGENE, UniProtKB/TrEMBL
	D3ZKA2	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-01	Robo3	roundabout guidance receptor 3	Robo3	roundabout, axon guidance receptor, homolog 3 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-03-01	Robo3	roundabout, axon guidance receptor, homolog 3 (Drosophila)	Robo3	roundabout homolog 3 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Robo3	roundabout homolog 3 (Drosophila)	Robo3_predicted	roundabout homolog 3 (Drosophila) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Robo3_predicted	roundabout homolog 3 (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM